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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q2 2024

Institutional positions in 89bio, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
145
−3 vs. Q1 2024
Shares held
103.4M
+5.08M (+5.2%) vs. Q1 2024
Total value
$828.4M
−$315.1M (−27.6%) vs. Q1 2024
New holders
20
66 more added
Sold out
23
43 more reduced

2 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 145 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2024: $828.4M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q1 2024.

Institutions holding ETNB in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.14,175,398$113.5M1.50%+1,408,450+11.0%Added
Janus Henderson Group PLC13,276,110$106.3M0.06%+672,728+5.3%Added
Suvretta Capital Management, LLC8,031,845$64.3M2.63%+1,733,841+27.5%Added
BVF Inc7,568,479$60.6M1.70%+3,521,125+87.0%Added
RTW Investments, LP7,378,548$59.1M0.92%00.0%Unchanged
BlackRock Inc.7,015,575$56.2M0.00%+377,591+5.7%Added
Vanguard Group Inc4,804,953$38.5M0.00%+81,982+1.7%Added
Pictet Asset Management Holding SA3,602,585$28.9M0.03%−107,606−2.9%Reduced
State Street Corp3,244,503$26.0M0.00%−2,299,085−41.5%Reduced
Westfield Capital Management Co LP2,319,365$18.6M0.09%+155,218+7.2%Added
Deep Track Capital, LP2,294,011$18.4M0.55%+2,294,011New
Laurion Capital Management LP2,180,931$17.5M0.57%−518,539−19.2%Reduced
Citadel Advisors LLC2,109,082$16.9M0.02%+539,540+34.4%Added
Geode Capital Management, LLC1,914,614$15.3M0.00%+173,747+10.0%Added
Redmile Group, LLC1,745,656$14.0M0.85%−518,910−22.9%Reduced
MPM Oncology Impact Management LP1,121,736$8.99M1.40%+153,994+15.9%Added
Millennium Management LLC1,010,352$8.09M0.01%−76,845−7.1%Reduced
Frazier Life Sciences Management, L.P.1,000,000$8.01M0.37%00.0%Unchanged
Goldman Sachs Group Inc904,817$7.25M0.00%+159,869+21.5%Added
Candriam Luxembourg S.C.A.848,079$6.79M0.04%+538,079+173.6%Added
Franklin Resources Inc832,220$6.67M0.00%+4,563+0.6%Added
Alyeska Investment Group, L.P.800,000$6.41M0.04%+500,000+166.7%Added
Orchard Capital Managment, LLC739,208$5.92M1.79%−10,142−1.4%Reduced
University of Wisconsin Foundation724,132$5.80M6.53%+225,995+45.4%Added
Northern Trust Corp723,864$5.80M0.00%+9,333+1.3%Added
Erste Asset Management GmbH723,000$5.74M0.08%+50,000+7.4%Added
Superstring Capital Management LP680,403$5.45M6.87%−260,884−27.7%Reduced
Charles Schwab Investment Management Inc667,118$5.34M0.00%+37,885+6.0%Added
Alliancebernstein L.P.556,527$4.46M0.00%+325,520+140.9%Added
Two Sigma Investments, LP533,717$4.28M0.01%+287,617+116.9%Added
Sphera Funds Management Ltd.526,547$4.22M0.69%+10,665+2.1%Added
Standard Life Aberdeen plc470,387$3.77M0.01%00.0%Unchanged
ExodusPoint Capital Management, LP459,230$3.68M0.04%+442,245+2,603.7%Added
Integral Health Asset Management, LLC450,000$3.60M0.36%+150,000+50.0%Added
Adage Capital Partners GP, L.L.C.400,000$3.20M0.01%−50,000−11.1%Reduced
Jane Street Group, LLC397,799$3.19M0.00%+282,377+244.6%Added
Wellington Management Group LLP357,536$2.86M0.00%+49,612+16.1%Added
Bank of America Corp326,369$2.61M0.00%−82,270−20.1%Reduced
Susquehanna International Group, LLP309,416$2.48M0.00%+129,454+71.9%Added
Bank of New York Mellon Corp299,689$2.40M0.00%+50,943+20.5%Added
Morgan Stanley292,445$2.34M0.00%−520,177−64.0%Reduced
Nuveen Asset Management, LLC283,101$2.27M0.00%−267,493−48.6%Reduced
Renaissance Technologies LLC279,400$2.24M0.00%+279,400New
Caption Management, LLC255,200$2.04M0.22%+114,216+81.0%Added
Newtyn Management, LLC240,000$1.92M0.36%−10,000−4.0%Reduced
Two Sigma Advisers, LP216,800$1.74M0.00%+73,300+51.1%Added
Raymond James & Associates182,943$1.47M0.00%+47,670+35.2%Added
Comerica Bank176,067$1.41M0.01%+5,067+3.0%Added
Braidwell LP164,227$1.32M0.04%+164,227New
Trexquant Investment LP163,616$1.31M0.02%+109,346+201.5%Added
State of Wisconsin Investment Board154,522$1.24M0.00%+35,767+30.1%Added
Rafferty Asset Management, LLC143,528$1.15M0.00%−318,424−68.9%Reduced
Royal Bank of Canada140,883$1.13M0.00%+9,887+7.5%Added
Swiss National Bank140,500$1.13M0.00%−6,700−4.6%Reduced
UBS Asset Management Americas Inc139,374$1.12M0.00%+66,674+91.7%Added
Raymond James Financial Services Advisors, Inc.136,471$1.09M0.00%+19,166+16.3%Added
Rhumbline Advisers128,944$1.03M0.00%+27,334+26.9%Added
DekaBank Deutsche Girozentrale90,000$1.02M0.00%00.0%Unchanged
UBS Group AG126,056$1.01M0.00%−194,676−60.7%Reduced
Jefferies Financial Group Inc.115,000$921.1K0.02%+35,099+43.9%Added
Jump Financial, LLC98,597$789.8K0.02%+52,294+112.9%Added
Nomura Holdings Inc95,009$761.0K0.00%+36,046+61.1%Added
Silverarc Capital Management, LLC92,298$739.3K0.18%00.0%Unchanged
Harbor Capital Advisors, Inc.85,898$688.0K0.05%+61,641+254.1%Added
Alps Advisors Inc76,750$614.8K0.00%+10,803+16.4%Added
Legal & General Group Plc75,346$603.2K0.00%−1,126−1.5%Reduced
California State Teachers Retirement System70,573$565.3K0.00%−4,429−5.9%Reduced
Barclays PLC65,289$523.0K0.00%−288,799−81.6%Reduced
American Century Companies Inc63,864$511.6K0.00%+43,842+219.0%Added
Dynamic Technology Lab Private Ltd60,648$486.0K0.05%+47,647+366.5%Added
HRT Financial LP59,202$474.0K0.00%+59,202New
Steward Partners Investment Advisory, LLC56,585$453.2K0.00%+20,475+56.7%Added
JPMorgan Chase & Co56,083$449.2K0.00%−4,730−7.8%Reduced
Wells Fargo & Company55,679$446.0K0.00%−45,835−45.2%Reduced
Mirae Asset Global ETFs Holdings Ltd.46,079$366.6K0.00%+46,079New
Jacobs Levy Equity Management, Inc45,664$365.8K0.00%+45,664New
MetLife Investment Management44,775$358.6K0.00%+4,178+10.3%Added
Pennant Investors, LP44,500$356.4K0.10%00.0%Unchanged
Corebridge Financial, Inc.43,593$349.2K0.00%+43,593New
Deutsche Bank AG42,418$339.8K0.00%−5,979−12.4%Reduced
Group One Trading, L.P.41,232$330.3K0.01%+29,269+244.7%Added
Squarepoint Ops LLC40,862$327.3K0.00%+40,862New
Balyasny Asset Management LLC40,656$325.7K0.00%+15,334+60.6%Added
Schonfeld Strategic Advisors LLC40,488$324.3K0.00%−93,566−69.8%Reduced
Citigroup Inc35,667$285.7K0.00%−382,592−91.5%Reduced
Price T Rowe Associates Inc34,182$274.0K0.00%+2,961+9.5%Added
Bourgeon Capital Management LLC33,650$269.5K0.05%00.0%Unchanged
Invesco Ltd.33,341$267.1K0.00%−1,561−4.5%Reduced
Walleye Capital LLC32,674$261.7K0.00%+32,674New
Gilliland Jeter Wealth Management LLC32,376$259.3K0.09%−550−1.7%Reduced
XTX Topco Ltd31,978$256.1K0.02%+31,978New
Manufacturers Life Insurance Company, The31,355$251.2K0.00%+3,557+12.8%Added
Engineers Gate Manager LP30,743$246.3K0.01%+19,907+183.7%Added
Algert Global LLC30,587$245.0K0.01%+7,203+30.8%Added
Eagle Asset Management Inc28,658$222.4K0.00%−651,109−95.8%Reduced
Fox Run Management, L.L.C.27,604$221.1K0.04%+15,402+126.2%Added
Voya Investment Management LLC27,336$219.0K0.00%+2,462+9.9%Added
Profund Advisors LLC27,100$217.1K0.01%−44,640−62.2%Reduced
New York State Common Retirement Fund26,167$209.6K0.00%−2,809−9.7%Reduced
SG Americas Securities, LLC25,292$203.0K0.00%+25,292New