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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q1 2022

Institutional positions in 89bio, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
+19 vs. Q4 2021
Shares held
17.1M
−237.3K (−1.4%) vs. Q4 2021
Total value
$64.3M
−$161.8M (−71.5%) vs. Q4 2021
New holders
23
24 more added
Sold out
4
18 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 69 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2022: $64.3M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q4 2021.

Institutions holding ETNB in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.4,965,769$18.7M0.41%00.0%Unchanged
OrbiMed Advisors LLC3,658,869$13.8M0.22%−70,573−1.9%Reduced
Wellington Management Group LLP1,782,053$6.72M0.00%−368,422−17.1%Reduced
BlackRock Inc.922,230$3.48M0.00%+70,489+8.3%Added
FMR LLC712,210$2.68M0.00%+74,684+11.7%Added
Franklin Resources Inc419,560$1.58M0.00%−384,860−47.8%Reduced
Bank of America Corp418,649$1.58M0.00%+312,587+294.7%Added
Citadel Advisors LLC413,119$1.56M0.00%+142,715+52.8%Added
Vanguard Group Inc405,419$1.53M0.00%−110,725−21.5%Reduced
Pekin Hardy Strauss, Inc.360,860$1.36M0.19%+178,005+97.3%Added
DAFNA Capital Management LLC324,053$1.22M0.32%+179,400+124.0%Added
Renaissance Technologies LLC263,400$993.0K0.00%+263,400New
JPMorgan Chase & Co249,752$941.0K0.00%+63,280+33.9%Added
Two Sigma Investments, LP220,418$831.0K0.00%+162,763+282.3%Added
Two Sigma Advisers, LP173,400$654.0K0.00%+104,700+152.4%Added
Geode Capital Management, LLC167,942$633.0K0.00%+2,941+1.8%Added
Orchard Capital Managment, LLC164,293$619.0K0.18%+14,100+9.4%Added
State Street Corp148,630$560.0K0.00%+1,806+1.2%Added
State of Wisconsin Investment Board120,271$453.0K0.00%+71,700+147.6%Added
Northern Trust Corp98,567$371.0K0.00%−3,823−3.7%Reduced
Gsa Capital Partners LLP92,815$350.0K0.05%+47,619+105.4%Added
Morgan Stanley70,309$264.0K0.00%+31,353+80.5%Added
Goldman Sachs Group Inc70,036$264.0K0.00%+59,791+583.6%Added
Millennium Management LLC68,217$257.0K0.00%+68,217New
CSS LLC66,367$250.0K0.01%+36,322+120.9%Added
D. E. Shaw & Co., Inc.65,908$248.0K0.00%+65,908New
Bridgeway Capital Management, LLC60,300$227.0K0.00%+60,300New
XTX Topco Ltd47,147$178.0K0.08%+47,147New
Nuveen Asset Management, LLC38,906$149.0K0.00%−17,234−30.7%Reduced
Royal Bank of Canada35,116$132.0K0.00%−109−0.3%Reduced
Glenmede Trust Co NA32,338$121.0K0.00%+14,409+80.4%Added
Public Employees Retirement Association of Colorado32,154$121.0K0.00%+32,154New
Bourgeon Capital Management LLC30,950$117.0K0.03%+10,600+52.1%Added
Bank of New York Mellon Corp30,632$116.0K0.00%−799−2.5%Reduced
Trexquant Investment LP26,433$100.0K0.00%+13,025+97.1%Added
UBS Group AG26,265$99.0K0.00%+18,989+261.0%Added
PDT Partners, LLC23,373$88.0K0.01%+23,373New
Barclays PLC21,544$81.0K0.00%+21,544New
Alps Advisors Inc21,026$79.0K0.00%−2,443−10.4%Reduced
Charles Schwab Investment Management Inc20,663$78.0K0.00%−4,146−16.7%Reduced
Cubist Systematic Strategies, LLC18,932$71.0K0.00%+18,932New
Susquehanna International Group, LLP18,366$69.0K0.00%+18,366New
Jump Financial, LLC16,700$63.0K0.00%+16,700New
Occudo Quantitative Strategies LP16,433$62.0K0.01%+16,433New
Pentwater Capital Management LP15,000$57.0K0.00%−85,000−85.0%Reduced
Deutsche Bank AG13,700$52.0K0.00%−640−4.5%Reduced
Alliancebernstein L.P.12,700$48.0K0.00%−1,300−9.3%Reduced
Schonfeld Strategic Advisors LLC12,200$46.0K0.00%+12,200New
Mirabella Financial Services LLP11,400$43.0K0.00%+11,400New
Rhumbline Advisers11,173$42.0K0.00%+11,173New
Penn Mutual Asset Management, LLC10,292$39.0K0.05%+10,292New
Acadian Asset Management LLC9,256$34.0K0.00%+9,256New
New York State Common Retirement Fund8,186$31.0K0.00%+5+0.1%Added
American International Group, Inc.4,899$18.0K0.00%−346−6.6%Reduced
California State Teachers Retirement System4,327$16.0K0.00%−923−17.6%Reduced
Tower Research Capital LLC (TRC)3,747$14.0K0.00%+927+32.9%Added
Prospera Financial Services Inc1,460$6.00K0.00%+1,460New
Amalgamated Bank1,226$5.00K0.00%+1,226New
Federated Hermes, Inc.1,326$5.00K0.00%+1,314+10,950.0%Added
Amalgamated Financial Corp.1,226$5.00K0.00%+1,226New
Point72 Hong Kong Ltd1,142$4.00K0.00%+1,142New
Citigroup Inc863$3.00K0.00%−2,283−72.6%Reduced
Aquatic Capital Management LLC900$3.00K0.00%−1,700−65.4%Reduced
Legal & General Group Plc820$3.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.1,000$3.00K0.00%+1,000New
Ameritas Investment Partners, Inc.560$2.00K0.00%00.0%Unchanged
Wells Fargo & Company141$1.00K0.00%−3,511−96.1%Reduced
Toronto Dominion Bank1$00.00%00.0%Unchanged
Simplex Trading, LLC145$00.00%+145New
Eventide Asset Management, LLC0$00.00%−716,670−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−488,197−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−152,098−100.0%Sold out
Altium Capital Management LP0$00.00%−148,000−100.0%Sold out