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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q2 2022

Institutional positions in 89bio, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
70
+2 vs. Q1 2022
Shares held
32.5M
+15.4M (+90.2%) vs. Q1 2022
Total value
$104.6M
+$40.2M (+62.5%) vs. Q1 2022
New holders
25
26 more added
Sold out
23
14 more reduced

1 institution that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 70 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2022: $104.6M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q1 2022.

Institutions holding ETNB in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,782,669$25.1M0.67%+2,816,900+56.7%Added
BVF Inc3,898,000$12.6M0.61%+3,898,000New
OrbiMed Advisors LLC3,658,869$11.8M0.23%00.0%Unchanged
Janus Henderson Group PLC1,690,140$5.45M0.00%+1,690,140New
Great Point Partners LLC1,400,000$4.51M1.16%+1,400,000New
Boxer Capital, LLC1,400,000$4.51M0.29%+1,400,000New
TCG Crossover Management, LLC1,133,196$3.65M1.55%+1,133,196New
Adage Capital Partners GP, L.L.C.1,100,000$3.54M0.01%+1,100,000New
Citadel Advisors LLC1,063,604$3.42M0.00%+650,485+157.5%Added
Vanguard Group Inc988,352$3.18M0.00%+582,933+143.8%Added
DAFNA Capital Management LLC766,774$2.47M0.67%+442,721+136.6%Added
BlackRock Inc.527,365$1.70M0.00%−394,865−42.8%Reduced
Deerfield Management Company, L.P. (Series C)506,100$1.63M0.03%+506,100New
Sphera Funds Management Ltd.450,000$1.45M0.28%+450,000New
Bank of America Corp440,314$1.42M0.00%+21,665+5.2%Added
Empery Asset Management, LP400,000$1.29M6.97%+400,000New
Pekin Hardy Strauss, Inc.319,455$1.03M0.16%−41,405−11.5%Reduced
Newtyn Management, LLC310,000$998.0K0.19%+310,000New
Renaissance Technologies LLC304,867$982.0K0.00%+41,467+15.7%Added
Alyeska Investment Group, L.P.300,000$966.0K0.01%+300,000New
Maven Securities LTD300,000$966.0K0.17%+300,000New
Walleye Capital LLC294,950$950.0K0.03%+294,950New
Schonfeld Strategic Advisors LLC243,974$787.0K0.01%+231,774+1,899.8%Added
Two Sigma Advisers, LP225,400$726.0K0.00%+52,000+30.0%Added
Citigroup Inc224,627$723.0K0.00%+223,764+25,928.6%Added
Pentwater Capital Management LP220,000$708.0K0.01%+205,000+1,366.7%Added
Laurion Capital Management LP187,100$602.0K0.03%+187,100New
Orchard Capital Managment, LLC168,493$592.0K0.18%+4,200+2.6%Added
Two Sigma Investments, LP156,914$505.0K0.00%−63,504−28.8%Reduced
Marshall Wace, LLP149,542$482.0K0.00%+149,542New
Millennium Management LLC149,122$480.0K0.00%+80,905+118.6%Added
State of Wisconsin Investment Board138,248$445.0K0.00%+17,977+14.9%Added
JPMorgan Chase & Co131,741$424.0K0.00%−118,011−47.3%Reduced
Invesco Ltd.123,356$397.0K0.00%+123,356New
CSS LLC109,278$352.0K0.02%+42,911+64.7%Added
Acadian Asset Management LLC105,424$340.0K0.00%+96,168+1,039.0%Added
Morgan Stanley98,359$317.0K0.00%+28,050+39.9%Added
D. E. Shaw & Co., Inc.94,036$303.0K0.00%+28,128+42.7%Added
Geode Capital Management, LLC91,045$293.0K0.00%−76,897−45.8%Reduced
UBS Group AG90,361$291.0K0.00%+64,096+244.0%Added
Goldman Sachs Group Inc86,061$277.0K0.00%+16,025+22.9%Added
Hudson Bay Capital Management LP77,126$248.0K0.00%+77,126New
Bridgeway Capital Management, LLC60,300$194.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP55,519$179.0K0.00%+37,153+202.3%Added
Ergoteles LLC47,600$153.0K0.00%+47,600New
Deutsche Bank AG47,375$152.0K0.00%+33,675+245.8%Added
Northern Trust Corp34,676$112.0K0.00%−63,891−64.8%Reduced
Glenmede Trust Co NA32,338$104.0K0.00%00.0%Unchanged
Bourgeon Capital Management LLC31,950$103.0K0.03%+1,000+3.2%Added
State Street Corp30,810$99.0K0.00%−117,820−79.3%Reduced
Bailard, Inc.29,692$96.0K0.00%+29,692New
Occudo Quantitative Strategies LP26,667$86.0K0.01%+10,234+62.3%Added
Cubist Systematic Strategies, LLC25,342$82.0K0.00%+6,410+33.9%Added
Barclays PLC24,464$79.0K0.00%+2,920+13.6%Added
Virtu Financial LLC20,222$65.0K0.01%+20,222New
Simplex Trading, LLC20,057$64.0K0.00%+19,912+13,732.4%Added
Raymond James & Associates19,507$63.0K0.00%+19,507New
PDT Partners, LLC10,274$33.0K0.00%−13,099−56.0%Reduced
Penn Mutual Asset Management, LLC10,292$33.0K0.04%00.0%Unchanged
Squarepoint Ops LLC10,348$33.0K0.00%+10,348New
Royal Bank of Canada4,510$15.0K0.00%−30,606−87.2%Reduced
FMR LLC2,079$7.00K0.00%−710,131−99.7%Reduced
Tower Research Capital LLC (TRC)2,313$7.00K0.00%−1,434−38.3%Reduced
Federated Hermes, Inc.981$3.00K0.00%−345−26.0%Reduced
Rockefeller Capital Management L.P.1,000$3.00K0.00%00.0%Unchanged
Capital Advisors, Ltd. LLC798$3.00K0.00%+798New
Advisor Group Holdings, Inc.282$1.00K0.00%+282New
New York State Common Retirement Fund86$00.00%−8,100−98.9%Reduced
Wells Fargo & Company57$00.00%−84−59.6%Reduced
Credit Suisse AG5$00.00%+5New
Wellington Management Group LLP0$00.00%−1,782,053−100.0%Sold out
Franklin Resources Inc0$00.00%−419,560−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−92,815−100.0%Sold out
XTX Topco Ltd0$00.00%−47,147−100.0%Sold out
Nuveen Asset Management, LLC0$00.00%−38,906−100.0%Sold out
Public Employees Retirement Association of Colorado0$00.00%−32,154−100.0%Sold out
Bank of New York Mellon Corp0$00.00%−30,632−100.0%Sold out
Trexquant Investment LP0$00.00%−26,433−100.0%Sold out
Alps Advisors Inc0$00.00%−21,026−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−20,663−100.0%Sold out
Jump Financial, LLC0$00.00%−16,700−100.0%Sold out
Alliancebernstein L.P.0$00.00%−12,700−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−11,400−100.0%Sold out
Rhumbline Advisers0$00.00%−11,173−100.0%Sold out
American International Group, Inc.0$00.00%−4,899−100.0%Sold out
California State Teachers Retirement System0$00.00%−4,327−100.0%Sold out
Prospera Financial Services Inc0$00.00%−1,460−100.0%Sold out
Amalgamated Bank0$00.00%−1,226−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−1,142−100.0%Sold out
Legal & General Group Plc0$00.00%−820−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−900−100.0%Sold out
Ameritas Investment Partners, Inc.0$00.00%−560−100.0%Sold out
Toronto Dominion Bank0$00.00%−1−100.0%Sold out
Amalgamated Financial Corp.––––Not filed