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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q1 2023

Institutional positions in 89bio, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
147
+42 vs. Q4 2022
Shares held
71.0M
+24.7M (+53.5%) vs. Q4 2022
Total value
$1.08B
+$492.4M (+83.7%) vs. Q4 2022
New holders
61
48 more added
Sold out
19
29 more reduced

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 147 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2023: $1.08B
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q4 2022.

Institutions holding ETNB in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,416,948$173.9M3.94%+2,461,538+27.5%Added
Janus Henderson Group PLC3,746,038$57.1M0.04%+2,726,659+267.5%Added
Adage Capital Partners GP, L.L.C.3,175,000$48.4M0.11%+1,187,408+59.7%Added
State Street Corp3,070,374$46.8M0.00%+2,965,364+2,823.9%Added
Cormorant Asset Management, LP2,800,000$42.6M2.81%+250,000+9.8%Added
Vanguard Group Inc2,606,285$39.7M0.00%+1,027,990+65.1%Added
Federated Hermes, Inc.2,353,115$35.8M0.09%+2,353,115New
Suvretta Capital Management, LLC2,210,536$33.7M1.62%+2,210,536New
Boxer Capital, LLC2,100,000$32.0M1.57%+700,000+50.0%Added
Holocene Advisors, LP2,095,043$31.9M0.16%+194,511+10.2%Added
Citadel Advisors LLC1,904,355$29.0M0.03%+954,043+100.4%Added
BVF Inc1,846,154$28.1M1.03%+1,846,154New
Avidity Partners Management LP1,842,976$28.1M0.93%+1,842,976New
Deep Track Capital, LP1,800,000$27.4M1.17%−2,050,000−53.2%Reduced
Morgan Stanley1,612,839$24.6M0.00%+1,507,728+1,434.4%Added
Millennium Management LLC1,543,647$23.5M0.03%−12,586−0.8%Reduced
BlackRock Inc.1,249,572$19.0M0.00%+179,991+16.8%Added
Marshall Wace, LLP1,129,471$17.2M0.04%−357,840−24.1%Reduced
Point72 Asset Management, L.P.1,021,647$15.6M0.06%−2,967−0.3%Reduced
Pictet Asset Management SA976,551$14.9M0.02%+976,551New
Two Sigma Advisers, LP901,100$13.7M0.04%+81,700+10.0%Added
Redmile Group, LLC900,000$13.7M0.59%+900,000New
Two Sigma Investments, LP867,961$13.2M0.04%+153,796+21.5%Added
Westfield Capital Management Co LP755,210$11.5M0.08%+755,210New
Lord, Abbett & Co. LLC750,612$11.4M0.04%+750,612New
Franklin Resources Inc710,832$10.8M0.01%+710,832New
Susquehanna International Group, LLP644,101$9.81M0.02%+412,851+178.5%Added
Eventide Asset Management, LLC642,073$9.78M0.18%+642,073New
Voloridge Investment Management, LLC574,780$8.75M0.04%+521,740+983.7%Added
Orchard Capital Managment, LLC551,879$8.41M2.81%00.0%Unchanged
Bank of America Corp544,529$8.29M0.00%+31,465+6.1%Added
JPMorgan Chase & Co534,105$8.13M0.00%+390,176+271.1%Added
Geode Capital Management, LLC503,945$7.68M0.00%+160,089+46.6%Added
Artal Group S.A.500,000$7.62M0.45%+100,000+25.0%Added
Alkeon Capital Management LLC500,000$7.62M0.05%+500,000New
Soleus Capital Management, L.P.494,000$7.52M0.93%+115,000+30.3%Added
Goldman Sachs Group Inc468,191$7.13M0.00%−191,733−29.1%Reduced
Silverarc Capital Management, LLC438,215$6.67M3.00%+438,215New
Laurion Capital Management LP436,885$6.65M0.30%+249,785+133.5%Added
Octagon Capital Advisors LP400,000$6.09M0.88%+20,000+5.3%Added
Citigroup Inc383,588$5.84M0.01%−155,091−28.8%Reduced
Schonfeld Strategic Advisors LLC353,246$5.38M0.05%−126,797−26.4%Reduced
Alyeska Investment Group, L.P.333,485$5.08M0.04%+333,485New
Rafferty Asset Management, LLC319,498$4.87M0.03%+319,498New
Driehaus Capital Management LLC301,581$4.59M0.06%+301,581New
EAM Investors, LLC286,420$4.36M0.86%+10,477+3.8%Added
Caption Management, LLC260,638$3.97M0.85%+260,638New
Ameriprise Financial Inc251,984$3.84M0.00%+251,984New
Great Point Partners LLC250,000$3.81M0.75%+250,000New
Parkman Healthcare Partners LLC246,956$3.76M0.82%−85,924−25.8%Reduced
ExodusPoint Capital Management, LP227,089$3.46M0.04%+227,089New
Jane Street Group, LLC218,376$3.33M0.01%+117,135+115.7%Added
Newtyn Management, LLC200,000$3.05M0.60%−110,000−35.5%Reduced
Ghost Tree Capital, LLC200,000$3.05M1.15%+200,000New
Affinity Asset Advisors, LLC200,000$3.05M1.17%+200,000New
Royal Bank of Canada199,836$3.04M0.00%+8,292+4.3%Added
Picton Mahoney Asset Management197,441$3.01M0.15%+85,841+76.9%Added
Pekin Hardy Strauss, Inc.186,644$2.84M0.44%−8,294−4.3%Reduced
Hudson Bay Capital Management LP171,835$2.62M0.03%+171,835New
Simplex Trading, LLC157,700$2.40M0.11%+88,017+126.3%Added
Tri Locum Partners LP157,225$2.39M0.73%+157,225New
D. E. Shaw & Co., Inc.156,503$2.38M0.00%+156,503New
Barclays PLC152,876$2.33M0.00%−256,269−62.6%Reduced
Candriam Luxembourg S.C.A.160,000$2.24M0.02%+160,000New
Squarepoint Ops LLC142,662$2.17M0.02%+103,076+260.4%Added
UBS Group AG141,124$2.15M0.00%+131,005+1,294.6%Added
Resolute Capital Asset Partners LLC125,000$1.90M1.39%+125,000New
Raymond James Financial Services Advisors, Inc.108,966$1.66M0.00%+6,189+6.0%Added
Tekla Capital Management LLC105,898$1.61M0.06%+105,898New
Northern Trust Corp101,592$1.55M0.00%+37,266+57.9%Added
Velan Capital Investment Management LP98,500$1.50M1.33%+98,500New
Dimensional Fund Advisors LP89,534$1.36M0.00%+18,508+26.1%Added
Connor, Clark & Lunn Investment Management Ltd.89,339$1.36M0.01%+89,339New
State of Wisconsin Investment Board79,448$1.21M0.00%00.0%Unchanged
1492 Capital Management LLC78,440$1.19M0.74%−250.0%Reduced
Gilder Gagnon Howe & Co LLC76,003$1.16M0.02%+26,126+52.4%Added
Monashee Investment Management LLC75,000$1.14M0.32%+75,000New
Raymond James & Associates70,103$1.07M0.00%+30,150+75.5%Added
Pentwater Capital Management LP70,000$1.07M0.02%+70,000New
Qube Research & Technologies Ltd68,531$1.04M0.01%+11,855+20.9%Added
Bellevue Group AG67,000$1.02M0.01%+67,000New
Wellington Management Group LLP60,916$927.8K0.00%+60,916New
Profund Advisors LLC58,076$884.5K0.05%+58,076New
Victory Capital Management Inc56,960$867.5K0.00%+56,960New
Virtu Financial LLC56,618$862.0K0.09%+56,618New
UBS Oconnor LLC55,939$852.0K0.02%+55,939New
Wells Fargo & Company53,424$813.6K0.00%+53,202+23,964.9%Added
Invesco Ltd.49,916$760.2K0.00%−6,311−11.2%Reduced
Walleye Trading LLC48,951$745.5K0.03%−12,998−21.0%Reduced
Belvedere Trading LLC47,949$730.3K0.32%+33,945+242.4%Added
Bank of New York Mellon Corp45,277$689.6K0.00%+18,194+67.2%Added
Landscape Capital Management, L.L.C.43,295$659.4K0.09%+43,295New
Bridgeway Capital Management, LLC42,500$647.3K0.02%−49,800−54.0%Reduced
Jump Financial, LLC37,675$573.8K0.02%−1,107−2.9%Reduced
Algert Global LLC36,965$563.0K0.03%+36,965New
Alps Advisors Inc33,312$507.3K0.00%+1,729+5.5%Added
Verition Fund Management LLC32,665$497.5K0.01%+32,665New
Bailard, Inc.28,892$440.0K0.02%00.0%Unchanged
Stephens Inc26,374$401.7K0.01%−16,846−39.0%Reduced
LMR Partners LLP25,431$387.3K0.01%+8,639+51.4%Added