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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q1 2025

Institutional positions in 89bio, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
187
+32 vs. Q4 2024
Shares held
154.3M
+33.4M (+27.6%) vs. Q4 2024
Total value
$1.14B
+$192.6M (+20.3%) vs. Q4 2024
New holders
54
90 more added
Sold out
22
33 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 187 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2025: $1.14B
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q4 2024.

Institutions holding ETNB in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC20,462,905$165.3M0.09%+3,948,849+23.9%Added
Ra Capital Management, L.P.19,889,683$144.6M2.41%+5,714,285+40.3%Added
Suvretta Capital Management, LLC14,335,244$104.2M4.22%+4,132,548+40.5%Added
BlackRock, Inc.10,075,344$73.2M0.00%+2,185,245+27.7%Added
Deep Track Capital, LP9,316,333$67.7M2.19%+2,838,084+43.8%Added
Vanguard Group Inc7,163,609$52.1M0.00%+1,471,278+25.8%Added
Avoro Capital Advisors LLC6,350,000$46.2M0.72%+2,250,000+54.9%Added
Citadel Advisors LLC5,086,836$37.0M0.04%+356,984+7.5%Added
Pictet Asset Management Holding SA4,204,887$30.6M0.03%+1,197,853+39.8%Added
State Street Corp4,030,307$29.3M0.00%+1,085,075+36.8%Added
Westfield Capital Management Co LP3,894,741$28.3M0.14%+7,947+0.2%Added
Geode Capital Management, LLC2,897,974$21.1M0.00%+690,366+31.3%Added
Logos Global Management LP2,500,000$18.2M3.23%+2,500,000New
Polar Capital Holdings Plc2,500,000$18.2M0.11%+2,500,000New
RTW Investments, LP1,967,527$14.3M0.22%−5,510,534−73.7%Reduced
Redmile Group, LLC1,886,444$13.7M1.30%−280,732−13.0%Reduced
Beck Bode, LLC1,815,524$13.2M2.46%+1,815,524New
Emerald Advisers, LLC1,550,671$11.3M0.51%+1,550,671New
Silverarc Capital Management, LLC1,510,498$11.0M2.29%+1,413,987+1,465.1%Added
University of Wisconsin Foundation1,153,357$8.38M7.12%+236,000+25.7%Added
Northern Trust Corp1,085,464$7.89M0.00%+230,677+27.0%Added
Emerald Mutual Fund Advisers Trust1,082,973$7.87M0.56%+1,082,973New
Integral Health Asset Management, LLC1,050,000$7.63M0.85%+50,000+5.0%Added
Nuveen, LLC1,035,957$7.53M0.00%+1,035,957New
Goldman Sachs Group Inc995,449$7.24M0.00%+188,367+23.3%Added
Charles Schwab Investment Management Inc985,771$7.17M0.00%+174,945+21.6%Added
Erste Asset Management GmbH883,000$6.50M0.08%+120,000+15.7%Added
Alyeska Investment Group, L.P.852,227$6.20M0.02%−73,170−7.9%Reduced
Rock Springs Capital Management LP844,441$6.14M0.35%+291,700+52.8%Added
Candriam Luxembourg S.C.A.831,823$6.05M0.04%−223,838−21.2%Reduced
Barclays PLC826,860$6.01M0.00%+186,886+29.2%Added
ADAR1 Capital Management, LLC804,220$5.85M1.12%+289,082+56.1%Added
Bank of America Corp781,952$5.68M0.00%+423,378+118.1%Added
Lord, Abbett & Co. LLC733,404$5.33M0.02%+733,404New
Woodline Partners LP700,754$5.09M0.03%+305,928+77.5%Added
FMR LLC690,012$5.02M0.00%+597,845+648.7%Added
Readystate Asset Management LP685,169$4.98M0.25%+685,169New
Morgan Stanley629,229$4.57M0.00%+287,278+84.0%Added
Sphera Funds Management Ltd.618,343$4.50M1.11%+61,811+11.1%Added
Dimensional Fund Advisors LP587,986$4.28M0.00%+245,757+71.8%Added
Renaissance Technologies LLC504,300$3.67M0.01%+206,600+69.4%Added
Sio Capital Management, LLC500,000$3.63M1.10%+500,000New
Infinitum Asset Management, LLC500,000$3.63M1.16%+500,000New
Orchard Capital Managment, LLC464,358$3.38M2.31%+421,733+989.4%Added
Millennium Management LLC452,454$3.29M0.00%−255,742−36.1%Reduced
Panagora Asset Management Inc429,392$3.12M0.02%+314,000+272.1%Added
Assenagon Asset Management S.A.428,895$3.12M0.01%+186,293+76.8%Added
Raymond James Financial Inc382,291$2.78M0.00%+4,921+1.3%Added
Vivo Capital, LLC376,804$2.74M0.36%+376,804New
Exome Asset Management LLC353,882$2.57M2.30%+128,559+57.1%Added
Balyasny Asset Management LLC336,649$2.45M0.01%−682,800−67.0%Reduced
Apis Capital Advisors, LLC315,000$2.29M1.11%+315,000New
Harbor Capital Advisors, Inc.314,772$2.29M0.10%+62,874+25.0%Added
Bank of New York Mellon Corp309,916$2.25M0.00%+61,760+24.9%Added
Eversept Partners, LP303,731$2.21M0.25%+303,731New
Laurion Capital Management LP292,467$2.13M0.16%−487,806−62.5%Reduced
UBS Asset Management Americas Inc268,798$1.95M0.00%+90,107+50.4%Added
Susquehanna Fundamental Investments, LLC266,466$1.94M0.03%+205,474+336.9%Added
Comerica Bank258,123$1.88M0.01%+1,540+0.6%Added
Hudson Bay Capital Management LP250,200$1.82M0.01%+250,200New
Wellington Management Group LLP250,193$1.82M0.00%−84,612−25.3%Reduced
Diadema Partners LP231,436$1.68M1.34%+231,436New
Royce & Associates LP226,050$1.64M0.02%+226,050New
F/M Investments LLC214,837$1.56M0.06%+214,837New
Citigroup Inc207,130$1.51M0.00%+94,789+84.4%Added
Swiss National Bank205,500$1.49M0.00%+43,900+27.2%Added
UBS Group AG203,207$1.48M0.00%+90,022+79.5%Added
Newtyn Management, LLC200,000$1.45M0.23%−40,000−16.7%Reduced
Two Sigma Investments, LP188,449$1.37M0.00%−49,072−20.7%Reduced
Algert Global LLC186,991$1.36M0.03%+1,584+0.9%Added
American Century Companies Inc185,295$1.35M0.00%+71,726+63.2%Added
Jefferies Financial Group Inc.181,000$1.32M0.02%+31,604+21.2%Added
Caption Management, LLC180,600$1.31M0.06%−85,762−32.2%Reduced
Qube Research & Technologies Ltd176,834$1.29M0.00%+176,834New
Affinity Asset Advisors, LLC175,000$1.27M0.20%+175,000New
Ghisallo Capital Management LLC175,000$1.27M0.11%+175,000New
Susquehanna International Group, LLP168,110$1.22M0.00%+103,931+161.9%Added
Alliancebernstein L.P.153,826$1.12M0.00%−888,310−85.2%Reduced
Rhumbline Advisers152,138$1.11M0.00%+22,158+17.0%Added
J. Goldman & Co LP142,565$1.04M0.04%+142,565New
Hennion & Walsh Asset Management, Inc.140,306$1.02M0.05%+45,812+48.5%Added
DekaBank Deutsche Girozentrale90,000$1.02M0.00%00.0%Unchanged
Rafferty Asset Management, LLC137,247$997.8K0.00%+48,502+54.7%Added
Voya Investment Management LLC132,791$965.4K0.00%+107,151+417.9%Added
State of Wisconsin Investment Board118,705$863.0K0.00%−44,468−27.3%Reduced
Invesco Ltd.115,751$841.5K0.00%+79,515+219.4%Added
Superstring Capital Management LP109,156$793.6K0.95%−23,826−17.9%Reduced
Legal & General Group Plc106,725$775.5K0.00%+30,837+40.6%Added
California State Teachers Retirement System103,977$755.9K0.00%+27,056+35.2%Added
Deutsche Bank AG101,666$739.1K0.00%+23,607+30.2%Added
Ikarian Capital, LLC100,000$727.0K0.24%+100,000New
Trexquant Investment LP99,183$721.1K0.01%+99,183New
Jacobs Levy Equity Management, Inc98,848$718.6K0.00%+98,848New
Prelude Capital Management, LLC98,087$713.1K0.07%+29,086+42.2%Added
B Group, Inc.95,623$695.2K0.60%+95,623New
Atom Investors LP93,167$677.3K0.08%+93,167New
Jain Global LLC88,482$643.3K0.01%+88,482New
AQR Capital Management LLC80,199$583.0K0.00%+80,199New
JPMorgan Chase & Co75,096$545.9K0.00%−233,363−75.7%Reduced
Wells Fargo & Company74,567$542.1K0.00%+24,229+48.1%Added