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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q4 2024

Institutional positions in 89bio, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
156
+14 vs. Q3 2024
Shares held
121.3M
+17.2M (+16.5%) vs. Q3 2024
Total value
$948.7M
+$177.8M (+23.1%) vs. Q3 2024
New holders
33
73 more added
Sold out
19
35 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 156 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2024: $948.7M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q3 2024.

Institutions holding ETNB in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC16,514,056$129.2M0.07%+1,355,838+8.9%Added
Ra Capital Management, L.P.14,175,398$110.9M1.48%00.0%Unchanged
Suvretta Capital Management, LLC10,202,696$79.8M2.96%+2,211,052+27.7%Added
BlackRock, Inc.7,890,099$61.7M0.00%+340,797+4.5%Added
RTW Investments, LP7,478,061$58.5M0.88%+99,513+1.3%Added
Deep Track Capital, LP6,478,249$50.7M1.90%+3,711,737+134.2%Added
Vanguard Group Inc5,692,331$44.5M0.00%+686,054+13.7%Added
Citadel Advisors LLC4,729,852$37.0M0.03%+2,173,125+85.0%Added
BVF Inc4,333,885$33.9M1.15%−2,477,746−36.4%Reduced
Avoro Capital Advisors LLC4,100,000$32.1M0.45%+4,100,000New
Westfield Capital Management Co LP3,886,794$30.4M0.13%+880,756+29.3%Added
Pictet Asset Management Holding SA3,007,034$23.5M0.03%−239,574−7.4%Reduced
State Street Corp2,945,232$23.0M0.00%−306,455−9.4%Reduced
Geode Capital Management, LLC2,207,608$17.3M0.00%+132,638+6.4%Added
Redmile Group, LLC2,167,176$16.9M1.18%+597,326+38.0%Added
Candriam Luxembourg S.C.A.1,055,661$8.26M0.05%+207,582+24.5%Added
Alliancebernstein L.P.1,042,136$8.15M0.00%+455,074+77.5%Added
Balyasny Asset Management LLC1,019,449$7.97M0.02%+1,019,449New
Frazier Life Sciences Management, L.P.1,000,000$7.82M0.32%00.0%Unchanged
Integral Health Asset Management, LLC1,000,000$7.82M0.69%+500,000+100.0%Added
Alyeska Investment Group, L.P.925,397$7.24M0.03%+116,833+14.4%Added
University of Wisconsin Foundation917,357$7.17M5.21%+193,225+26.7%Added
Northern Trust Corp854,787$6.68M0.00%+60,075+7.6%Added
Charles Schwab Investment Management Inc810,826$6.34M0.00%+89,776+12.5%Added
Goldman Sachs Group Inc807,082$6.31M0.00%+73,585+10.0%Added
Laurion Capital Management LP780,273$6.10M0.38%−30,260−3.7%Reduced
Erste Asset Management GmbH763,000$5.95M0.07%00.0%Unchanged
Millennium Management LLC708,196$5.54M0.00%+326,215+85.4%Added
Barclays PLC639,974$5.00M0.00%+425,206+198.0%Added
Sphera Funds Management Ltd.556,532$4.35M0.80%+19,985+3.7%Added
Rock Springs Capital Management LP552,741$4.32M0.16%+552,741New
StemPoint Capital LP545,800$4.27M1.07%+545,800New
ADAR1 Capital Management, LLC515,138$4.03M0.83%+508,578+7,752.7%Added
Walleye Capital LLC432,846$3.38M0.03%−2,452−0.6%Reduced
Woodline Partners LP394,826$3.09M0.02%+341,479+640.1%Added
Raymond James Financial Inc377,370$2.95M0.00%+377,370New
Bank of America Corp358,574$2.80M0.00%+32,867+10.1%Added
BNP Paribas Arbitrage, SA351,331$2.75M0.00%+351,331New
Adage Capital Partners GP, L.L.C.350,000$2.74M0.00%−525,000−60.0%Reduced
Dimensional Fund Advisors LP342,229$2.68M0.00%+342,229New
Morgan Stanley341,951$2.67M0.00%−58,287−14.6%Reduced
Wellington Management Group LLP334,805$2.62M0.00%+15,760+4.9%Added
Standard Life Aberdeen plc329,338$2.58M0.00%−141,049−30.0%Reduced
Ally Bridge Group (NY) LLC317,833$2.49M2.13%+317,833New
JPMorgan Chase & Co308,459$2.41M0.00%+208,992+210.1%Added
Renaissance Technologies LLC297,700$2.33M0.00%−14,324−4.6%Reduced
Nuveen Asset Management, LLC286,492$2.24M0.00%−3,420−1.2%Reduced
Caption Management, LLC266,362$2.08M0.09%+11,162+4.4%Added
Comerica Bank256,583$2.01M0.01%+30,603+13.5%Added
Harbor Capital Advisors, Inc.251,898$1.97M0.09%+23,968+10.5%Added
Bank of New York Mellon Corp248,156$1.94M0.00%+9,314+3.9%Added
Assenagon Asset Management S.A.242,602$1.90M0.00%+242,602New
Newtyn Management, LLC240,000$1.88M0.33%00.0%Unchanged
Two Sigma Investments, LP237,521$1.86M0.00%−131,167−35.6%Reduced
Exome Asset Management LLC225,323$1.76M1.33%−75,277−25.0%Reduced
Algert Global LLC185,407$1.45M0.03%+123,190+198.0%Added
UBS Asset Management Americas Inc178,691$1.40M0.00%+37,693+26.7%Added
State of Wisconsin Investment Board163,173$1.28M0.00%+22,928+16.3%Added
Swiss National Bank161,600$1.26M0.00%+21,100+15.0%Added
Jane Street Group, LLC151,997$1.19M0.00%+13,269+9.6%Added
Jefferies Financial Group Inc.149,396$1.17M0.01%+49,396+49.4%Added
Superstring Capital Management LP132,982$1.04M0.91%−462,221−77.7%Reduced
Rhumbline Advisers129,980$1.02M0.00%+4,125+3.3%Added
DekaBank Deutsche Girozentrale90,000$965.0K0.00%00.0%Unchanged
Panagora Asset Management Inc115,392$902.4K0.00%+115,392New
American Century Companies Inc113,569$888.1K0.00%+31,564+38.5%Added
UBS Group AG113,185$885.1K0.00%−128,319−53.1%Reduced
Royal Bank of Canada113,050$883.0K0.00%−11,430−9.2%Reduced
Citigroup Inc112,341$878.5K0.00%+47,314+72.8%Added
Two Sigma Advisers, LP112,100$876.6K0.00%−51,100−31.3%Reduced
Silverarc Capital Management, LLC96,511$754.7K0.17%+4,213+4.6%Added
Hennion & Walsh Asset Management, Inc.94,494$738.9K0.03%+94,494New
FMR LLC92,167$720.7K0.00%+18,781+25.6%Added
Rafferty Asset Management, LLC88,745$694.0K0.00%−38,636−30.3%Reduced
Group One Trading, L.P.82,219$643.0K0.02%+68,732+509.6%Added
PDT Partners, LLC80,918$632.8K0.06%−88,327−52.2%Reduced
Deutsche Bank AG78,059$610.4K0.00%+25,353+48.1%Added
California State Teachers Retirement System76,921$601.5K0.00%+8,570+12.5%Added
Legal & General Group Plc75,888$593.4K0.00%00.0%Unchanged
Prelude Capital Management, LLC69,001$539.6K0.05%−26,499−27.7%Reduced
Susquehanna International Group, LLP64,179$501.9K0.00%−275,892−81.1%Reduced
Susquehanna Fundamental Investments, LLC60,992$477.0K0.01%+60,992New
CWM Advisors, LLC51,717$404.4K0.05%−4,395−7.8%Reduced
Mirae Asset Global ETFs Holdings Ltd.51,154$399.9K0.00%+1,169+2.3%Added
Wells Fargo & Company50,338$393.6K0.00%+11,203+28.6%Added
MetLife Investment Management50,265$393.1K0.00%+5,033+11.1%Added
BIT Capital GmbH47,469$371.2K0.03%+47,469New
Price T Rowe Associates Inc47,292$370.0K0.00%+4,976+11.8%Added
Orchard Capital Managment, LLC42,625$333.3K0.13%+751+1.8%Added
Corebridge Financial, Inc.41,622$325.5K0.00%−3,141−7.0%Reduced
Gilliland Jeter Wealth Management LLC39,439$308.4K0.10%−6,720−14.6%Reduced
Intech Investment Management LLC38,619$302.0K0.00%+17,053+79.1%Added
SG Americas Securities, LLC36,325$284.0K0.00%+5,612+18.3%Added
Invesco Ltd.36,236$283.4K0.00%+3,893+12.0%Added
Persistent Asset Partners Ltd26,842$257.7K0.22%+26,842New
Manufacturers Life Insurance Company, The30,531$238.8K0.00%−94−0.3%Reduced
Pale Fire Capital SE30,439$238.0K0.06%+30,439New
Bourgeon Capital Management LLC30,254$236.6K0.04%−2,806−8.5%Reduced
ProShare Advisors LLC29,149$227.9K0.00%+7,070+32.0%Added
Ameriprise Financial Inc28,230$220.8K0.00%+14,641+107.7%Added