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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q4 2022

Institutional positions in 89bio, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
106
+21 vs. Q3 2022
Shares held
46.3M
+7.45M (+19.2%) vs. Q3 2022
Total value
$589.5M
+$364.5M (+162.0%) vs. Q3 2022
New holders
39
34 more added
Sold out
18
19 more reduced

1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 106 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2022: $589.5M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q3 2022.

Institutions holding ETNB in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.8,955,410$114.0M2.31%+1,172,741+15.1%Added
Deep Track Capital, LP3,850,000$49.0M2.14%+1,214,000+46.1%Added
OrbiMed Advisors LLC3,658,869$46.6M0.89%00.0%Unchanged
Cormorant Asset Management, LP2,550,000$32.5M2.18%+2,550,000New
Adage Capital Partners GP, L.L.C.1,987,592$25.3M0.06%−262,408−11.7%Reduced
Holocene Advisors, LP1,900,532$24.2M0.15%+1,900,532New
Vanguard Group Inc1,578,295$20.1M0.00%−93,289−5.6%Reduced
Millennium Management LLC1,556,233$19.8M0.02%+706,686+83.2%Added
Marshall Wace, LLP1,487,311$18.9M0.05%+1,037,931+231.0%Added
Boxer Capital, LLC1,400,000$17.8M0.96%00.0%Unchanged
BlackRock Inc.1,069,581$13.6M0.00%+159,539+17.5%Added
Point72 Asset Management, L.P.1,024,614$13.0M0.05%+1,024,614New
Janus Henderson Group PLC1,019,379$13.0M0.01%+231,387+29.4%Added
Citadel Advisors LLC950,312$12.1M0.01%−184,110−16.2%Reduced
Two Sigma Advisers, LP819,400$10.4M0.03%+262,500+47.1%Added
Commodore Capital LP758,244$9.65M1.45%+758,244New
Two Sigma Investments, LP714,165$9.09M0.03%+224,641+45.9%Added
Goldman Sachs Group Inc659,924$8.40M0.00%+271,344+69.8%Added
Orchard Capital Managment, LLC551,879$7.03M2.35%00.0%Unchanged
Citigroup Inc538,679$6.86M0.01%+128,032+31.2%Added
Bank of America Corp513,064$6.53M0.00%−60,900−10.6%Reduced
Schonfeld Strategic Advisors LLC480,043$6.11M0.05%+130,183+37.2%Added
Walleye Capital LLC479,756$6.11M0.13%+45,635+10.5%Added
Ikarian Capital, LLC454,000$5.78M2.40%+254,000+127.0%Added
Barclays PLC409,145$5.21M0.00%+20,163+5.2%Added
Artal Group S.A.400,000$5.09M0.29%+400,000New
Octagon Capital Advisors LP380,000$4.84M0.75%+380,000New
Soleus Capital Management, L.P.379,000$4.82M0.69%+49,000+14.8%Added
Geode Capital Management, LLC343,856$4.38M0.00%+102,148+42.3%Added
Parkman Healthcare Partners LLC332,880$4.24M1.13%+107,880+47.9%Added
DAFNA Capital Management LLC324,173$4.13M1.16%−330,689−50.5%Reduced
Newtyn Management, LLC310,000$3.95M0.81%00.0%Unchanged
Cubist Systematic Strategies, LLC291,025$3.70M0.03%+248,208+579.7%Added
EAM Investors, LLC275,943$3.51M0.73%+85,225+44.7%Added
Susquehanna International Group, LLP231,250$2.94M0.01%+231,250New
Renaissance Technologies LLC215,167$2.74M0.00%−18,600−8.0%Reduced
Pekin Hardy Strauss, Inc.194,938$2.48M0.39%−132,398−40.4%Reduced
Royal Bank of Canada191,544$2.44M0.00%+60,358+46.0%Added
Laurion Capital Management LP187,100$2.38M0.07%00.0%Unchanged
Sphera Funds Management Ltd.180,600$2.30M0.72%−478,184−72.6%Reduced
JPMorgan Chase & Co143,929$1.83M0.00%−79,809−35.7%Reduced
Alliancebernstein L.P.130,877$1.67M0.00%+130,877New
EAM Global Investors LLC125,394$1.60M0.41%+125,394New
Picton Mahoney Asset Management111,600$1.42M0.07%+2,000+1.8%Added
Morgan Stanley105,111$1.34M0.00%−27,254−20.6%Reduced
State Street Corp105,010$1.34M0.00%+42,100+66.9%Added
Raymond James Financial Services Advisors, Inc.102,777$1.31M0.00%−57,417−35.8%Reduced
Jane Street Group, LLC101,241$1.29M0.00%+81,441+411.3%Added
Bridgeway Capital Management, LLC92,300$1.17M0.03%00.0%Unchanged
Boothbay Fund Management, LLC88,535$1.13M0.04%+52,775+147.6%Added
State of Wisconsin Investment Board79,448$1.01M0.00%00.0%Unchanged
1492 Capital Management LLC78,465$998.9K0.65%+78,465New
Dimensional Fund Advisors LP71,026$904.0K0.00%00.0%Unchanged
Simplex Trading, LLC69,683$887.0K0.04%+69,683New
Alpha Paradigm Partners, LLC67,433$858.0K0.35%+67,433New
Northern Trust Corp64,326$818.9K0.00%−4,351−6.3%Reduced
Trexquant Investment LP62,034$789.7K0.02%+62,034New
Walleye Trading LLC61,949$788.6K0.02%+39,347+174.1%Added
Qube Research & Technologies Ltd56,676$721.5K0.00%+39,893+237.7%Added
Invesco Ltd.56,227$715.8K0.00%−54,841−49.4%Reduced
HRT Financial LP56,194$715.0K0.01%+56,194New
J. Goldman & Co LP54,060$688.2K0.05%+54,060New
Voloridge Investment Management, LLC53,040$675.2K0.00%+53,040New
Acadian Asset Management LLC51,861$660.0K0.00%−71,244−57.9%Reduced
Pura Vida Investments, LLC50,000$636.5K0.11%+50,000New
Gilder Gagnon Howe & Co LLC49,877$634.9K0.01%+49,877New
Gsa Capital Partners LLP47,653$607.0K0.08%+47,653New
Stephens Inc43,220$550.2K0.01%+43,220New
Raymond James & Associates39,953$508.6K0.00%−554−1.4%Reduced
Squarepoint Ops LLC39,586$503.9K0.00%+39,586New
Jump Financial, LLC38,782$493.7K0.03%+38,782New
Endurant Capital Management LP36,784$468.3K0.19%+36,784New
Bank of Montreal34,233$436.1K0.00%−5,700−14.3%Reduced
Alps Advisors Inc31,583$402.1K0.00%+31,583New
Bailard, Inc.28,892$367.8K0.01%00.0%Unchanged
Bank of New York Mellon Corp27,083$344.8K0.00%+10,580+64.1%Added
Dynamic Technology Lab Private Ltd22,362$285.0K0.03%+11,683+109.4%Added
683 Capital Management, LLC22,178$282.3K0.03%+22,178New
Balyasny Asset Management LLC22,159$282.1K0.00%+22,159New
Bayesian Capital Management, LP18,009$229.3K0.03%+3,400+23.3%Added
Man Group plc17,804$226.6K0.00%+17,804New
LMR Partners LLP16,792$213.8K0.00%+16,792New
Charles Schwab Investment Management Inc15,302$194.8K0.00%00.0%Unchanged
Belvedere Trading LLC14,004$178.3K0.10%+14,004New
Quantbot Technologies LP12,800$162.9K0.01%+6,900+116.9%Added
Tudor Investment Corp Et Al11,142$142.0K0.00%+11,142New
SG Americas Securities, LLC10,619$135.0K0.00%+10,619New
UBS Group AG10,119$128.8K0.00%−70,462−87.4%Reduced
Fox Run Management, L.L.C.10,053$128.0K0.05%+10,053New
Gladstone Institutional Advisory LLC10,000$127.3K0.01%+10,000New
Group One Trading, L.P.9,841$125.3K0.00%+9,441+2,360.3%Added
Deutsche Bank AG8,437$107.4K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,059$39.0K0.00%−8,393−73.3%Reduced
Dorsey Wright & Associates2,900$36.9K0.01%+2,900New
FMR LLC2,079$26.5K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,582$21.0K0.00%+400+33.8%Added
Bourgeon Capital Management LLC1,000$12.7K0.00%−1,500−60.0%Reduced
Rockefeller Capital Management L.P.1,000$12.0K0.00%00.0%Unchanged
Capital Advisors, Ltd. LLC798$10.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.473$6.02K0.00%+107+29.2%Added