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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q1 2024

Institutional positions in 89bio, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
150
−3 vs. Q4 2023
Shares held
98.4M
+4.22M (+4.5%) vs. Q4 2023
Total value
$1.14B
+$92.6M (+8.8%) vs. Q4 2023
New holders
22
69 more added
Sold out
25
52 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 150 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2024: $1.14B
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q4 2023.

Institutions holding ETNB in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.12,766,948$148.6M1.89%+1,350,000+11.8%Added
Janus Henderson Group PLC12,603,382$146.6M0.08%+3,688,241+41.4%Added
RTW Investments, LP7,378,548$85.9M1.27%+1,799,617+32.3%Added
BlackRock Inc.6,637,984$77.3M0.00%+1,183,788+21.7%Added
Suvretta Capital Management, LLC6,298,004$73.3M3.09%+1,409,570+28.8%Added
State Street Corp5,543,588$64.5M0.00%+144,230+2.7%Added
Vanguard Group Inc4,722,971$55.0M0.00%+415,386+9.6%Added
BVF Inc4,047,354$47.1M1.30%00.0%Unchanged
Pictet Asset Management Holding SA3,710,191$43.2M0.05%−847,489−18.6%Reduced
Holocene Advisors, LP3,450,689$40.2M0.15%−39,939−1.1%Reduced
Laurion Capital Management LP2,699,470$31.4M0.87%−4,732−0.2%Reduced
Redmile Group, LLC2,264,566$26.4M0.97%+295,164+15.0%Added
Westfield Capital Management Co LP2,164,147$25.2M0.13%+402,999+22.9%Added
Geode Capital Management, LLC1,740,867$20.3M0.00%+363,157+26.4%Added
Citadel Advisors LLC1,569,542$18.3M0.02%−608,797−27.9%Reduced
Millennium Management LLC1,087,197$12.7M0.01%+528,312+94.5%Added
Frazier Life Sciences Management, L.P.1,000,000$11.6M0.49%−1,000,000−50.0%Reduced
MPM Oncology Impact Management LP967,742$11.3M1.81%+967,742New
Superstring Capital Management LP941,287$11.0M7.24%−80,190−7.9%Reduced
Franklin Resources Inc827,657$9.63M0.00%−460.0%Reduced
Morgan Stanley812,622$9.46M0.00%−676,638−45.4%Reduced
Orchard Capital Managment, LLC749,350$8.72M2.56%+10,142+1.4%Added
Goldman Sachs Group Inc744,948$8.67M0.00%+113,836+18.0%Added
Northern Trust Corp714,531$8.32M0.00%+96,530+15.6%Added
Erste Asset Management GmbH673,000$7.80M0.11%+170,000+33.8%Added
Charles Schwab Investment Management Inc629,233$7.32M0.00%+129,880+26.0%Added
Eagle Asset Management Inc679,767$7.29M0.04%−22,328−3.2%Reduced
Nuveen Asset Management, LLC550,594$6.41M0.00%+308,205+127.2%Added
Sphera Funds Management Ltd.515,882$6.00M0.97%+107,208+26.2%Added
University of Wisconsin Foundation498,137$5.80M6.54%+371,621+293.7%Added
Standard Life Aberdeen plc470,387$5.48M0.01%+256,195+119.6%Added
Rafferty Asset Management, LLC461,952$5.38M0.02%+8,278+1.8%Added
Adage Capital Partners GP, L.L.C.450,000$5.24M0.01%−2,675,000−85.6%Reduced
Citigroup Inc418,259$4.87M0.01%+203,657+94.9%Added
Bank of America Corp408,639$4.76M0.00%+136,740+50.3%Added
Barclays PLC354,088$4.12M0.00%−189,464−34.9%Reduced
UBS Group AG320,732$3.73M0.00%+36,235+12.7%Added
Candriam Luxembourg S.C.A.310,000$3.61M0.02%+30,000+10.7%Added
Wellington Management Group LLP307,924$3.58M0.00%+68,897+28.8%Added
Alyeska Investment Group, L.P.300,000$3.49M0.02%−283,187−48.6%Reduced
Integral Health Asset Management, LLC300,000$3.49M0.34%+300,000New
Newtyn Management, LLC250,000$2.91M0.58%−22,500−8.3%Reduced
Bank of New York Mellon Corp248,746$2.90M0.00%+26,326+11.8%Added
Two Sigma Investments, LP246,100$2.86M0.01%+117,342+91.1%Added
Alliancebernstein L.P.231,007$2.69M0.00%−67,982−22.7%Reduced
Susquehanna International Group, LLP179,962$2.09M0.00%+13,752+8.3%Added
Parkman Healthcare Partners LLC179,899$2.09M0.26%−39,549−18.0%Reduced
Comerica Bank171,000$1.99M0.01%+15,070+9.7%Added
Swiss National Bank147,200$1.71M0.00%+4,400+3.1%Added
Two Sigma Advisers, LP143,500$1.67M0.00%−23,800−14.2%Reduced
Caption Management, LLC140,984$1.64M0.18%−119,016−45.8%Reduced
Raymond James & Associates135,273$1.57M0.00%+26,870+24.8%Added
Schonfeld Strategic Advisors LLC134,054$1.56M0.01%+56,296+72.4%Added
Royal Bank of Canada130,996$1.53M0.00%−117,935−47.4%Reduced
State of Wisconsin Investment Board118,755$1.38M0.00%−3,108−2.6%Reduced
Raymond James Financial Services Advisors, Inc.117,305$1.37M0.00%+13,019+12.5%Added
Jane Street Group, LLC115,422$1.34M0.00%+26,125+29.3%Added
Capstone Investment Advisors, LLC103,767$1.21M0.02%+103,767New
Rhumbline Advisers101,610$1.18M0.00%+17,521+20.8%Added
Wells Fargo & Company101,514$1.18M0.00%+15,659+18.2%Added
Natixis99,000$1.15M0.01%+99,000New
Silverarc Capital Management, LLC92,298$1.07M0.30%−66,421−41.8%Reduced
DekaBank Deutsche Girozentrale90,000$1.02M0.00%00.0%Unchanged
Jefferies Financial Group Inc.79,901$930.0K0.02%+15,785+24.6%Added
1492 Capital Management LLC79,168$921.5K0.51%−50−0.1%Reduced
Legal & General Group Plc76,472$890.1K0.00%+2,903+3.9%Added
California State Teachers Retirement System75,002$873.0K0.00%−147−0.2%Reduced
UBS Asset Management Americas Inc72,700$846.2K0.00%+13,600+23.0%Added
Profund Advisors LLC71,740$835.1K0.03%−1,401−1.9%Reduced
Alps Advisors Inc65,947$767.6K0.01%+13,491+25.7%Added
JPMorgan Chase & Co60,813$707.9K0.00%−138,119−69.4%Reduced
Credit Suisse AG60,103$699.6K0.00%+3,268+5.7%Added
Nomura Holdings Inc58,963$686.3K0.01%−23,037−28.1%Reduced
D. E. Shaw & Co., Inc.55,493$645.9K0.00%+41,536+297.6%Added
Trexquant Investment LP54,270$631.7K0.01%+54,270New
Deutsche Bank AG48,397$563.3K0.00%−330,443−87.2%Reduced
Tudor Investment Corp Et Al47,630$554.4K0.01%+47,630New
Jump Financial, LLC46,303$539.0K0.01%+46,303New
Pennant Investors, LP44,500$518.0K0.14%00.0%Unchanged
MetLife Investment Management40,597$472.5K0.00%+7,978+24.5%Added
American International Group, Inc.38,968$453.6K0.00%+7,140+22.4%Added
Steward Partners Investment Advisory, LLC36,110$420.3K0.00%+36,110New
UBS Oconnor LLC35,962$418.6K0.01%−43,113−54.5%Reduced
Invesco Ltd.34,902$406.3K0.00%−66,316−65.5%Reduced
Bourgeon Capital Management LLC33,650$391.7K0.08%−1,650−4.7%Reduced
Gilliland Jeter Wealth Management LLC32,926$383.3K0.13%+13,926+73.3%Added
Price T Rowe Associates Inc31,221$364.0K0.00%+7,000+28.9%Added
Corton Capital Inc.29,452$342.8K0.13%−6,027−17.0%Reduced
Sherbrooke Park Advisers LLC29,002$337.6K0.07%+29,002New
New York State Common Retirement Fund28,976$337.3K0.00%+2,935+11.3%Added
Manufacturers Life Insurance Company, The27,798$323.6K0.00%−5,593−16.8%Reduced
Entropy Technologies, LP27,154$316.1K0.03%−6,353−19.0%Reduced
Parkwood LLC26,701$311.0K0.03%−17,505−39.6%Reduced
Balyasny Asset Management LLC25,322$294.7K0.00%+25,322New
Voya Investment Management LLC24,874$289.5K0.00%−469−1.9%Reduced
Harbor Capital Advisors, Inc.24,257$282.0K0.04%+19,498+409.7%Added
Algert Global LLC23,384$272.2K0.01%−23,440−50.1%Reduced
E Fund Management Co., Ltd.21,830$254.1K0.02%−2,533−10.4%Reduced
ProShare Advisors LLC20,737$241.4K0.00%+5,319+34.5%Added
Arizona State Retirement System20,492$238.5K0.00%+235+1.2%Added