Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 280
- +14 vs. Q3 2025
- Shares held
- 126.4M
- +4.65M (+3.8%) vs. Q3 2025
- Total value
- $3.17B
- +$415.1M (+15.0%) vs. Q3 2025
- New holders
- 61
- 89 more added
- Sold out
- 47
- 102 more reduced
7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Man Group plc | 144,271 | $3.62M | 0.01% | +77,069+114.7% | Added |
| Swiss National Bank | 149,500 | $3.76M | 0.00% | +3,300+2.3% | Added |
| Rock Springs Capital Management LP | 150,500 | $3.78M | 0.19% | +58,500+63.6% | Added |
| HighVista Strategies LLC | 150,776 | $3.79M | 0.98% | +5,047+3.5% | Added |
| JPMorgan Chase & Co | 157,754 | $3.96M | 0.00% | +104,238+194.8% | Added |
| Gotham Asset Management, LLC | 168,455 | $4.23M | 0.02% | +41,297+32.5% | Added |
| ExodusPoint Capital Management, LP | 171,156 | $4.30M | 0.05% | −23,602−12.1% | Reduced |
| Rafferty Asset Management, LLC | 171,456 | $4.31M | 0.01% | +3,104+1.8% | Added |
| Bank of Montreal | 176,571 | $4.44M | 0.00% | +16,265+10.1% | Added |
| UBS Asset Management Americas Inc | 178,888 | $4.49M | 0.00% | +11,424+6.8% | Added |
| Fiduciary Trust Co | 180,254 | $4.53M | 0.05% | −17,925−9.0% | Reduced |
| Dimensional Fund Advisors LP | 180,925 | $4.54M | 0.00% | +162,235+868.0% | Added |
| California Public Employees Retirement System | 186,328 | $4.68M | 0.00% | +40,140+27.5% | Added |
| Barclays PLC | 187,712 | $4.72M | 0.00% | −81,815−30.4% | Reduced |
| Goldman Sachs Group Inc | 189,205 | $4.75M | 0.00% | +64,832+52.1% | Added |
| Silvercrest Asset Management Group LLC | 190,759 | $4.79M | 0.03% | +233+0.1% | Added |
| Apis Capital Advisors, LLC | 192,000 | $4.82M | 0.84% | +192,000 | New |
| Squarepoint Ops LLC | 192,156 | $4.83M | 0.01% | +139,322+263.7% | Added |
| HRT Financial LP | 192,488 | $4.83M | 0.02% | −161,161−45.6% | Reduced |
| Jump Financial, LLC | 193,876 | $4.87M | 0.06% | −83,772−30.2% | Reduced |
| Trexquant Investment LP | 194,592 | $4.89M | 0.04% | −392,347−66.8% | Reduced |
| Integral Health Asset Management, LLC | 200,000 | $5.02M | 0.25% | −50,000−20.0% | Reduced |
| Acadian Asset Management LLC | 205,986 | $5.17M | 0.01% | +193,533+1,554.1% | Added |
| Tudor Investment Corp Et Al | 215,000 | $5.40M | 0.03% | +215,000 | New |
| Canada Pension Plan Investment Board | 222,200 | $5.58M | 0.00% | +5,200+2.4% | Added |
| Invesco Ltd. | 225,976 | $5.68M | 0.00% | +42,960+23.5% | Added |
| Janus Henderson Group PLC | 230,320 | $5.79M | 0.00% | +195,908+569.3% | Added |
| Sphera Funds Management Ltd. | 250,961 | $6.30M | 1.32% | +187,301+294.2% | Added |
| Caption Management, LLC | 254,563 | $6.39M | 0.28% | −50,437−16.5% | Reduced |
| Natixis | 257,268 | $6.46M | 0.03% | +205,029+392.5% | Added |
| Bank of New York Mellon Corp | 271,925 | $6.83M | 0.00% | +23,731+9.6% | Added |
| J. Goldman & Co LP | 285,992 | $7.18M | 0.28% | +2,839+1.0% | Added |
| Granite Investment Partners, LLC | 327,094 | $8.22M | 0.49% | +327,094 | New |
| 683 Capital Management, LLC | 330,000 | $8.29M | 0.69% | +42,000+14.6% | Added |
| Schroder Investment Management Group | 329,134 | $8.31M | 0.01% | +156,047+90.2% | Added |
| Rhenman & Partners Asset Management AB | 374,450 | $9.41M | 0.88% | +142,200+61.2% | Added |
| Pictet Asset Management Holding SA | 390,884 | $9.84M | 0.01% | +27,434+7.5% | Added |
| Ossiam | 431,779 | $10.8M | 0.22% | −124,174−22.3% | Reduced |
| D. E. Shaw & Co., Inc. | 449,676 | $11.3M | 0.01% | −7,115−1.6% | Reduced |
| Voloridge Investment Management, LLC | 461,186 | $11.6M | 0.04% | −531,083−53.5% | Reduced |
| First Trust Advisors LP | 495,947 | $12.5M | 0.01% | +495,947 | New |
| Susquehanna International Group, LLP | 533,909 | $13.4M | 0.02% | +220,025+70.1% | Added |
| Simplify Asset Management Inc. | 538,008 | $13.5M | 0.22% | +431,120+403.3% | Added |
| Woodline Partners LP | 542,981 | $13.6M | 0.05% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 557,591 | $14.0M | 0.01% | −414,883−42.7% | Reduced |
| Two Sigma Investments, LP | 562,361 | $14.1M | 0.02% | +310,293+123.1% | Added |
| SG Americas Securities, LLC | 567,046 | $14.2M | 0.02% | +149,654+35.9% | Added |
| Ameriprise Financial Inc | 589,597 | $14.8M | 0.00% | −128,106−17.8% | Reduced |
| Point72 Asset Management, L.P. | 597,672 | $15.0M | 0.02% | +380,601+175.3% | Added |
| Citigroup Inc | 622,158 | $15.6M | 0.01% | +177,186+39.8% | Added |
| Renaissance Technologies LLC | 633,058 | $15.9M | 0.02% | −89,837−12.4% | Reduced |
| Charles Schwab Investment Management Inc | 644,445 | $16.2M | 0.00% | −2,637−0.4% | Reduced |
| Citadel Advisors LLC | 648,229 | $16.3M | 0.01% | +61,777+10.5% | Added |
| Nuveen, LLC | 681,819 | $17.1M | 0.00% | +16,771+2.5% | Added |
| Northern Trust Corp | 696,521 | $17.5M | 0.00% | +147,273+26.8% | Added |
| Los Angeles Capital Management LLC | 951,716 | $19.7M | 0.07% | +330,926+53.3% | Added |
| Kynam Capital Management, LP | 908,607 | $22.8M | 1.49% | +100,000+12.4% | Added |
| Millennium Management LLC | 946,459 | $23.8M | 0.02% | −397,267−29.6% | Reduced |
| Bank of America Corp | 956,773 | $24.0M | 0.00% | −520,752−35.2% | Reduced |
| Marshall Wace, LLP | 990,848 | $24.9M | 0.02% | +594,113+149.8% | Added |
| Bank of Nova Scotia | 1,070,141 | $26.9M | 0.04% | −386,084−26.5% | Reduced |
| Hudson Bay Capital Management LP | 1,179,828 | $29.6M | 0.17% | +761,328+181.9% | Added |
| Norges Bank | 1,198,444 | $30.1M | 0.00% | +1,198,444 | New |
| Deutsche Bank AG | 1,385,263 | $34.8M | 0.01% | −119,194−7.9% | Reduced |
| Jennison Associates LLC | 1,504,299 | $37.8M | 0.02% | −2,843,756−65.4% | Reduced |
| Geode Capital Management, LLC | 2,025,669 | $50.9M | 0.00% | −47,244−2.3% | Reduced |
| AQR Capital Management LLC | 2,276,687 | $57.2M | 0.03% | −2,210,667−49.3% | Reduced |
| OrbiMed Advisors LLC | 2,429,868 | $61.0M | 1.25% | +106,500+4.6% | Added |
| Siren, L.L.C. | 2,578,396 | $64.8M | 1.93% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 3,706,510 | $93.1M | 0.43% | +1,056,280+39.9% | Added |
| Suvretta Capital Management, LLC | 4,139,426 | $104.0M | 2.59% | +1,261,426+43.8% | Added |
| UBS Group AG | 4,186,222 | $105.2M | 0.02% | +756,317+22.1% | Added |
| State Street Corp | 4,613,446 | $115.9M | 0.00% | +575,802+14.3% | Added |
| BlackRock, Inc. | 6,260,113 | $157.3M | 0.00% | −8,352−0.1% | Reduced |
| RTW Investments, LP | 7,666,764 | $192.6M | 1.93% | +7,666,764 | New |
| Deep Track Capital, LP | 7,750,000 | $194.7M | 4.44% | −250,382−3.1% | Reduced |
| Morgan Stanley | 9,173,004 | $230.4M | 0.01% | −470,244−4.9% | Reduced |
| Vanguard Group Inc | 10,674,865 | $268.2M | 0.00% | +687,471+6.9% | Added |
| Avoro Capital Advisors LLC | 12,222,222 | $307.0M | 3.02% | 00.0% | Unchanged |
| Wellington Management Group LLP | 12,721,352 | $319.6M | 0.06% | +3,430,392+36.9% | Added |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −3,447,156−100.0% | Sold out |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −903,500−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −241,977−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −130,828−100.0% | Sold out |
| Worldquant Millennium Advisors LLC | 0 | $0 | 0.00% | −111,979−100.0% | Sold out |
| Bleakley Financial Group, LLC | 0 | $0 | 0.00% | −79,305−100.0% | Sold out |
| Landscape Capital Management, L.L.C. | 0 | $0 | 0.00% | −75,000−100.0% | Sold out |
| J. Safra Sarasin Holding AG | 0 | $0 | 0.00% | −70,500−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −66,336−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −65,156−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −53,540−100.0% | Sold out |
| Highland Capital Management, LLC | 0 | $0 | 0.00% | −50,133−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −47,282−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −43,239−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −34,182−100.0% | Sold out |
| Voleon Capital Management LP | 0 | $0 | 0.00% | −32,221−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −31,446−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −27,223−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −25,500−100.0% | Sold out |
| PharVision Advisers, LLC | 0 | $0 | 0.00% | −22,291−100.0% | Sold out |