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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
255
−2 vs. Q4 2024
Shares held
128.0M
+1.77M (+1.4%) vs. Q4 2024
Total value
$2.80B
−$1.23B (−30.5%) vs. Q4 2024
New holders
50
90 more added
Sold out
52
76 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 255 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2025: $2.80B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding APLS in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Zurcher Kantonalbank (Zurich Cantonalbank)19,891$435.0K0.00%−457−2.2%Reduced
GWN Securities Inc.27,190$454.1K0.03%+27,190New
Duncan Williams Asset Management, LLC21,125$462.0K0.17%00.0%Unchanged
Eastern Bank21,500$470.2K0.01%00.0%Unchanged
Mercer Global Advisors Inc21,762$475.9K0.00%+9,129+72.3%Added
Colony Group, LLC21,883$478.6K0.00%+11,862+118.4%Added
Boothbay Fund Management, LLC22,997$502.9K0.02%+22,997New
Scientech Research LLC23,395$511.6K0.14%+9,062+63.2%Added
Marshall Wace, LLP23,574$515.6K0.00%−61,921−72.4%Reduced
Acadian Asset Management LLC23,976$522.0K0.00%+22,052+1,146.2%Added
Virginia Retirement Systems Et Al24,665$539.4K0.00%+24,665New
Manufacturers Life Insurance Company, The24,937$545.4K0.00%−27,960−52.9%Reduced
China Universal Asset Management Co., Ltd.25,176$550.6K0.05%−1,200−4.5%Reduced
HSBC Holdings PLC24,999$551.7K0.00%−102,829−80.4%Reduced
Graham Capital Management, L.P.28,136$615.3K0.02%+28,136New
Rhenman & Partners Asset Management AB28,250$617.8K0.07%−167,341−85.6%Reduced
Parallax Volatility Advisers, L.P.28,350$620.0K0.02%+28,350New
Bridgefront Capital, LLC29,070$635.8K0.18%+29,070New
Captrust Financial Advisors29,280$640.4K0.00%+16,651+131.8%Added
Ensign Peak Advisors, Inc29,397$642.9K0.00%−49,700−62.8%Reduced
Susquehanna International Group, LLP29,505$645.3K0.00%+3,288+12.5%Added
Y-Intercept (Hong Kong) Ltd29,577$646.8K0.04%+29,577New
Group One Trading, L.P.30,041$657.0K0.03%+30,041New
Voleon Capital Management LP30,191$660.3K0.05%+30,191New
Mirae Asset Global ETFs Holdings Ltd.29,559$666.6K0.00%+19,944+207.4%Added
Handelsbanken Fonder AB30,600$669.0K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio32,975$721.2K0.00%−2,897−8.1%Reduced
Merit Financial Group, LLC33,762$738.4K0.01%+25,806+324.4%Added
Gotham Asset Management, LLC34,285$749.8K0.01%+9,986+41.1%Added
Guggenheim Capital LLC35,348$773.1K0.01%+2,741+8.4%Added
Profund Advisors LLC35,657$779.8K0.03%−8,662−19.5%Reduced
Bayesian Capital Management, LP37,900$828.9K0.14%+37,900New
Janus Henderson Group PLC34,412$835.5K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey38,569$843.5K0.01%+1,025+2.7%Added
Russell Investments Group, Ltd.38,903$850.8K0.00%+32,796+537.0%Added
Landscape Capital Management, L.L.C.38,988$852.7K0.08%−10,998−22.0%Reduced
EFG Asset Management (North America) Corp.39,363$860.9K0.14%−3,794−8.8%Reduced
Mackenzie Financial Corp41,533$908.3K0.00%+5,175+14.2%Added
Engineers Gate Manager LP42,172$922.3K0.02%+42,172New
Pallas Capital Advisors LLC42,534$930.2K0.04%+29,165+218.2%Added
Envestnet Asset Management Inc43,717$956.1K0.00%+15,766+56.4%Added
Hennion & Walsh Asset Management, Inc.44,166$965.9K0.04%+14,426+48.5%Added
Alliancebernstein L.P.44,912$982.2K0.00%+13,572+43.3%Added
Erste Asset Management GmbH42,000$1.02M0.01%00.0%Unchanged
J. Safra Sarasin Holding AG47,096$1.03M0.02%−13,251−22.0%Reduced
T. Rowe Price Investment Management, Inc.47,713$1.04M0.00%00.0%Unchanged
New York State Common Retirement Fund48,837$1.07M0.00%00.0%Unchanged
Treasurer of the State of North Carolina49,005$1.07M0.00%+3,090+6.7%Added
Raymond James Financial Inc51,978$1.14M0.00%+2,963+6.0%Added
Bayforest Capital Ltd52,338$1.14M0.50%+42,499+431.9%Added
Tudor Investment Corp Et Al52,980$1.16M0.01%+52,980New
Cerity Partners LLC54,444$1.19M0.00%+7,777+16.7%Added
Baird Financial Group, Inc.55,529$1.21M0.00%+864+1.6%Added
Quest Partners LLC56,104$1.23M0.13%+38,918+226.5%Added
The PNC Financial Services Group, Inc.58,391$1.28M0.00%+238+0.4%Added
DekaBank Deutsche Girozentrale55,000$1.29M0.00%00.0%Unchanged
California State Teachers Retirement System59,778$1.31M0.00%−10,910−15.4%Reduced
Wealth Enhancement Advisory Services, LLC70,159$1.53M0.00%+36,565+108.8%Added
Bleakley Financial Group, LLC73,137$1.60M0.05%−368−0.5%Reduced
Assenagon Asset Management S.A.74,325$1.63M0.00%+44,332+147.8%Added
Ikarian Capital, LLC75,000$1.64M0.53%+71,406+1,986.8%Added
Legal & General Group Plc79,070$1.73M0.00%−7,701−8.9%Reduced
Rock Springs Capital Management LP80,000$1.75M0.10%00.0%Unchanged
State of Wisconsin Investment Board84,615$1.85M0.00%+4,233+5.3%Added
Price T Rowe Associates Inc90,700$1.98M0.00%−267,878−74.7%Reduced
State Board of Administration of Florida Retirement System91,818$2.01M0.00%00.0%Unchanged
CWM, LLC98,258$2.15M0.01%+53,663+120.3%Added
HighVista Strategies LLC108,714$2.38M0.92%00.0%Unchanged
Verition Fund Management LLC110,510$2.42M0.01%+60,100+119.2%Added
Steward Partners Investment Advisory, LLC122,175$2.67M0.02%+7,130+6.2%Added
Rhumbline Advisers124,454$2.72M0.00%−1,106−0.9%Reduced
Voya Investment Management LLC125,401$2.74M0.00%+2,250+1.8%Added
California Public Employees Retirement System126,706$2.77M0.00%+470.0%Added
Old West Investment Management, LLC128,192$2.80M1.01%+14,569+12.8%Added
Connor, Clark & Lunn Investment Management Ltd.131,895$2.88M0.01%+118,417+878.6%Added
Swiss National Bank132,600$2.90M0.00%−11,100−7.7%Reduced
Alyeska Investment Group, L.P.150,000$3.28M0.01%+150,000New
Bank of Montreal158,573$3.47M0.00%+77,582+95.8%Added
Candriam Luxembourg S.C.A.159,054$3.48M0.02%−380,548−70.5%Reduced
Toronto Dominion Bank162,190$3.55M0.01%−834,863−83.7%Reduced
Granahan Investment Management Inc175,696$3.84M0.19%+21,278+13.8%Added
Rafferty Asset Management, LLC180,134$3.94M0.02%−61,340−25.4%Reduced
Sphera Funds Management Ltd.181,346$3.97M0.98%−24,905−12.1%Reduced
Schonfeld Strategic Advisors LLC181,400$3.97M0.03%+181,400New
ING Groep NV184,200$4.03M0.03%+184,200New
Barclays PLC191,237$4.18M0.00%+31,672+19.8%Added
Two Sigma Advisers, LP191,800$4.19M0.01%+191,800New
PDT Partners, LLC195,165$4.27M0.30%+57,471+41.7%Added
First Trust Advisors LP199,209$4.36M0.00%+173,564+676.8%Added
Fiduciary Trust Co203,336$4.45M0.06%−26,465−11.5%Reduced
Macquarie Group Ltd204,803$4.48M0.01%+3,736+1.9%Added
Victory Capital Management Inc215,152$4.71M0.00%−347,117−61.7%Reduced
Aquatic Capital Management LLC215,876$4.72M0.12%+86,667+67.1%Added
Prudential Financial Inc217,880$4.77M0.01%+19,820+10.0%Added
Woodline Partners LP218,850$4.79M0.03%+29,373+15.5%Added
UBS Asset Management Americas Inc222,634$4.87M0.00%+9,747+4.6%Added
Citadel Advisors LLC224,096$4.90M0.00%+111,673+99.3%Added
Edgestream Partners, L.P.241,287$5.28M0.18%+131,404+119.6%Added
ExodusPoint Capital Management, LP250,414$5.48M0.07%+250,414New
Voloridge Investment Management, LLC253,790$5.55M0.02%−92,095−26.6%Reduced