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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2024

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
260
−2 vs. Q3 2024
Shares held
126.7M
+8.67M (+7.3%) vs. Q3 2024
Total value
$4.04B
+$639.2M (+18.8%) vs. Q3 2024
New holders
61
98 more added
Sold out
63
72 more reduced

3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 260 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2024: $4.04B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2024.

Institutions holding APLS in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Xponance, Inc.14,072$449.0K0.00%+749+5.6%Added
Scientech Research LLC14,333$457.4K0.13%+14,333New
Vident Advisory, LLC14,564$464.7K0.01%+14,564New
ADAR1 Capital Management, LLC15,000$478.6K0.10%−2,252−13.1%Reduced
KLP Kapitalforvaltning AS15,800$504.2K0.00%+15,800New
Creative Planning16,214$517.4K0.00%+16,214New
Panagora Asset Management Inc16,701$532.9K0.00%−12,685−43.2%Reduced
E Fund Management Co., Ltd.17,162$547.6K0.03%+4,046+30.8%Added
Quest Partners LLC17,186$548.4K0.07%+16,976+8,083.8%Added
Allianz Asset Management GmbH18,800$599.9K0.00%+11,400+154.1%Added
Teachers Retirement System of the State of Kentucky18,912$603.0K0.01%00.0%Unchanged
Syon Capital LLC19,455$620.8K0.06%+19,455New
CIBC Private Wealth Group, LLC18,864$622.5K0.00%−546−2.8%Reduced
Tower Research Capital LLC (TRC)19,965$637.1K0.01%+14,654+275.9%Added
D. E. Shaw & Co., Inc.20,000$638.2K0.00%+20,000New
Zurcher Kantonalbank (Zurich Cantonalbank)20,348$649.3K0.00%+1,136+5.9%Added
Sippican Capital Advisors20,753$662.2K0.48%−9,560−31.5%Reduced
Duncan Williams Asset Management, LLC21,125$674.1K0.27%00.0%Unchanged
Arizona State Retirement System21,204$676.6K0.00%−1,512−6.7%Reduced
Eastern Bank21,500$686.1K0.01%+10,000+87.0%Added
Teacher Retirement System of Texas21,649$691.0K0.00%+1,864+9.4%Added
Gotham Asset Management, LLC24,299$775.4K0.01%+24,299New
First Trust Advisors LP25,645$818.3K0.00%+8,344+48.2%Added
Susquehanna International Group, LLP26,217$836.6K0.00%−145,575−84.7%Reduced
China Universal Asset Management Co., Ltd.26,376$841.7K0.08%+2,956+12.6%Added
Envestnet Asset Management Inc27,951$891.9K0.00%−127,713−82.0%Reduced
Hennion & Walsh Asset Management, Inc.29,740$949.0K0.04%+17,115+135.6%Added
Assenagon Asset Management S.A.29,993$957.1K0.00%−2,114,422−98.6%Reduced
Handelsbanken Fonder AB30,600$976.0K0.00%+3,000+10.9%Added
Prelude Capital Management, LLC31,255$997.3K0.08%+2,300+7.9%Added
Alliancebernstein L.P.31,340$1.00M0.00%−9,678−23.6%Reduced
Savant Capital, LLC31,525$1.01M0.01%+9,407+42.5%Added
Guggenheim Capital LLC32,607$1.04M0.01%−5,322−14.0%Reduced
Wealth Enhancement Advisory Services, LLC33,594$1.07M0.00%+19,641+140.8%Added
Janus Henderson Group PLC34,412$1.10M0.00%00.0%Unchanged
Canada Pension Plan Investment Board35,200$1.12M0.00%+35,200New
Readystate Asset Management LP35,561$1.13M0.05%+35,561New
Public Employees Retirement System of Ohio35,872$1.14M0.00%−2,054−5.4%Reduced
Mackenzie Financial Corp36,358$1.16M0.00%−9,127−20.1%Reduced
Police & Firemen's Retirement System of New Jersey37,544$1.20M0.01%+37,544New
TD Asset Management Inc38,692$1.23M0.00%−199,520−83.8%Reduced
Erste Asset Management GmbH42,000$1.37M0.02%00.0%Unchanged
EFG Asset Management (North America) Corp.43,157$1.38M0.19%+10,087+30.5%Added
Profund Advisors LLC44,319$1.41M0.05%+5,705+14.8%Added
CWM, LLC44,595$1.42M0.01%+20,873+88.0%Added
Treasurer of the State of North Carolina45,915$1.47M0.01%+290+0.6%Added
Cerity Partners LLC46,667$1.48M0.00%+15,286+48.7%Added
T. Rowe Price Investment Management, Inc.47,713$1.52M0.00%−2,937,559−98.4%Reduced
New York State Common Retirement Fund48,837$1.56M0.00%−327,776−87.0%Reduced
Raymond James Financial Inc49,015$1.56M0.00%+49,015New
Man Group plc49,292$1.57M0.00%+32,550+194.4%Added
Landscape Capital Management, L.L.C.49,986$1.60M0.17%+23,086+85.8%Added
Affinity Asset Advisors, LLC50,000$1.60M0.25%+50,000New
Verition Fund Management LLC50,410$1.61M0.01%+50,410New
SG Americas Securities, LLC52,401$1.67M0.01%+28,932+123.3%Added
Manufacturers Life Insurance Company, The52,897$1.69M0.00%−8,324−13.6%Reduced
DekaBank Deutsche Girozentrale55,000$1.74M0.00%00.0%Unchanged
Baird Financial Group, Inc.54,665$1.74M0.00%+27,495+101.2%Added
The PNC Financial Services Group, Inc.58,153$1.86M0.00%−309−0.5%Reduced
J. Safra Sarasin Holding AG60,347$1.93M0.03%−13,230−18.0%Reduced
Fieldview Capital Management, LLC61,405$1.96M0.30%+61,405New
California State Teachers Retirement System70,688$2.26M0.00%−5,852−7.6%Reduced
Bleakley Financial Group, LLC73,505$2.35M0.07%−5,451−6.9%Reduced
Ensign Peak Advisors, Inc79,097$2.52M0.00%−1,900−2.3%Reduced
Rock Springs Capital Management LP80,000$2.55M0.10%00.0%Unchanged
State of Wisconsin Investment Board80,382$2.56M0.01%−657−0.8%Reduced
Bank of Montreal80,991$2.58M0.00%+41,635+105.8%Added
Marshall Wace, LLP85,495$2.73M0.00%+63,705+292.4%Added
Legal & General Group Plc86,771$2.77M0.00%−1,192−1.4%Reduced
Cinctive Capital Management LP86,991$2.78M0.15%+86,991New
State Board of Administration of Florida Retirement System91,818$2.93M0.01%00.0%Unchanged
Jane Street Group, LLC95,985$3.06M0.00%+76,705+397.8%Added
Banque Pictet & Cie SA97,299$3.10M0.03%+23,416+31.7%Added
KBC Group NV104,287$3.33M0.01%+101,655+3,862.3%Added
HighVista Strategies LLC108,714$3.47M1.29%+72,739+202.2%Added
Edgestream Partners, L.P.109,883$3.51M0.15%+10,482+10.5%Added
Citadel Advisors LLC112,423$3.59M0.00%−85,710−43.3%Reduced
Old West Investment Management, LLC113,623$3.63M1.47%+11,220+11.0%Added
Steward Partners Investment Advisory, LLC115,045$3.67M0.03%+2,250+2.0%Added
Exome Asset Management LLC119,467$3.81M2.87%+19,100+19.0%Added
Capital Fund Management S.A.121,433$3.87M0.04%−121,801−50.1%Reduced
Voya Investment Management LLC123,151$3.93M0.00%+35,185+40.0%Added
Rhumbline Advisers125,560$4.01M0.00%−295−0.2%Reduced
California Public Employees Retirement System126,659$4.04M0.00%−10,935−7.9%Reduced
Ieq Capital, LLC126,710$4.04M0.04%+118,404+1,425.5%Added
HSBC Holdings PLC127,828$4.08M0.00%+9,341+7.9%Added
Aquatic Capital Management LLC129,209$4.12M0.11%+126,809+5,283.7%Added
PDT Partners, LLC137,694$4.39M0.39%−7,825−5.4%Reduced
Swiss National Bank143,700$4.59M0.00%−10,400−6.7%Reduced
Granahan Investment Management Inc154,418$4.93M0.21%+3,840+2.6%Added
Barclays PLC159,565$5.09M0.00%−96,332−37.6%Reduced
Squarepoint Ops LLC166,962$5.33M0.01%+76,621+84.8%Added
Woodline Partners LP189,477$6.05M0.04%+913+0.5%Added
Cubist Systematic Strategies, LLC191,687$6.12M0.10%+191,687New
Citigroup Inc192,161$6.13M0.01%+179,999+1,480.0%Added
Point72 Europe (London) LLP192,694$6.15M0.36%+192,694New
Rhenman & Partners Asset Management AB195,591$6.24M0.64%−171,909−46.8%Reduced
Prudential Financial Inc198,060$6.32M0.01%−89,700−31.2%Reduced
Intrinsic Edge Capital Management LLC200,000$6.38M0.87%+200,000New
Macquarie Group Ltd201,067$6.42M0.01%+17,778+9.7%Added