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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
284
+32 vs. Q3 2023
Shares held
113.8M
−76.3K (−0.1%) vs. Q3 2023
Total value
$6.82B
+$2.48B (+57.1%) vs. Q3 2023
New holders
65
79 more added
Sold out
33
110 more reduced

4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 284 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2023: $6.82B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2023.

Institutions holding APLS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
ProShare Advisors LLC7,571$453.2K0.00%−121−1.6%Reduced
E Fund Management Co., Ltd.7,657$458.3K0.03%−3,341−30.4%Reduced
Maryland State Retirement & Pension System7,881$471.8K0.01%00.0%Unchanged
Great West Life Assurance Co8,030$478.0K0.00%+689+9.4%Added
Oppenheimer Asset Management Inc.8,030$480.7K0.01%−1,839−18.6%Reduced
Prelude Capital Management, LLC8,240$493.2K0.04%+8,240New
Snowden Capital Advisors LLC9,162$548.4K0.02%−288−3.0%Reduced
Public Employees Retirement Association of Colorado9,749$584.0K0.00%00.0%Unchanged
Raymond James Financial Services Advisors, Inc.9,840$589.0K0.00%−2,260−18.7%Reduced
Diametric Capital, LP9,913$593.4K0.36%+9,913New
Tudor Investment Corp Et Al9,962$596.3K0.01%−40,150−80.1%Reduced
Wynnefield Capital Inc10,000$598.6K0.23%00.0%Unchanged
Silverarc Capital Management, LLC10,000$598.6K0.18%+10,000New
MML Investors Services, LLC10,128$606.0K0.00%+1,759+21.0%Added
Cutler Group LP10,201$610.0K0.08%−26,921−72.5%Reduced
Level Four Advisory Services, LLC10,466$626.5K0.04%+10,466New
Weiss Asset Management LP10,677$639.1K0.05%+10,677New
KPP Advisory Services LLC11,196$670.2K0.59%+1,675+17.6%Added
Cambridge Trust Co11,500$688.4K0.03%00.0%Unchanged
HighTower Advisors, LLC11,609$695.0K0.00%+11,609New
Oppenheimer & Co Inc12,230$732.1K0.01%+391+3.3%Added
Hennion & Walsh Asset Management, Inc.12,302$736.4K0.04%−172−1.4%Reduced
Neuberger Berman Group LLC12,458$745.7K0.00%+12,458New
Millennium Management LLC12,527$749.9K0.00%−32,602−72.2%Reduced
Boothbay Fund Management, LLC12,656$757.6K0.03%+4,806+61.2%Added
Walleye Trading LLC12,831$768.1K0.01%−12,649−49.6%Reduced
Xponance, Inc.12,927$773.8K0.01%−939−6.8%Reduced
Allianz Asset Management GmbH13,600$814.1K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.13,710$820.7K0.16%+10,682+352.8%Added
Mariner, LLC13,901$832.1K0.00%+3,460+33.1%Added
Portman Square Capital LLP14,053$841.2K0.15%−32,079−69.5%Reduced
Nomura Holdings Inc14,695$879.6K0.01%+14,695New
Twinbeech Capital LP14,772$884.3K0.01%−135,457−90.2%Reduced
Y-Intercept (Hong Kong) Ltd15,008$898.4K0.08%+15,008New
Intech Investment Management LLC15,342$918.4K0.01%−5,965−28.0%Reduced
Raymond James & Associates15,387$921.1K0.00%−26,633−63.4%Reduced
Sippican Capital Advisors16,004$958.0K0.75%+170+1.1%Added
TIG Advisors, LLC17,093$1.02M0.15%+17,093New
Bayesian Capital Management, LP17,275$1.03M0.11%+17,275New
Assetmark, Inc17,344$1.04M0.00%+5,975+52.6%Added
CIBC Private Wealth Group, LLC17,910$1.07M0.00%00.0%Unchanged
Birchview Capital, LP18,000$1.08M0.84%00.0%Unchanged
Teacher Retirement System of Texas19,031$1.14M0.01%−4,068−17.6%Reduced
Jacobs Levy Equity Management, Inc19,154$1.15M0.01%−90,354−82.5%Reduced
Stifel Financial Corp19,916$1.19M0.00%−10,118−33.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)20,123$1.20M0.00%+6,102+43.5%Added
Amalgamated Bank20,457$1.23M0.01%−1,728−7.8%Reduced
Cubist Systematic Strategies, LLC21,530$1.29M0.02%−21,391−49.8%Reduced
Jefferies Financial Group Inc.22,544$1.35M0.02%+18,236+423.3%Added
Brinker Capital Investments, LLC19,749$1.35M0.02%−7,647−27.9%Reduced
Orion Portfolio Solutions, LLC19,749$1.35M0.02%−7,647−27.9%Reduced
Profund Advisors LLC22,558$1.35M0.06%−12,595−35.8%Reduced
Handelsbanken Fonder AB22,600$1.35M0.01%+5,400+31.4%Added
Arizona State Retirement System23,040$1.38M0.01%−171−0.7%Reduced
Schroder Investment Management Group23,682$1.42M0.00%+23,682New
Principal Financial Group Inc23,863$1.43M0.00%−3,120−11.6%Reduced
SEI Investments Co25,333$1.52M0.00%−7,340−22.5%Reduced
Baird Financial Group, Inc.25,917$1.55M0.00%−15,361−37.2%Reduced
Steward Partners Investment Advisory, LLC29,800$1.78M0.02%+5,250+21.4%Added
Skandinaviska Enskilda Banken AB (publ)30,481$1.82M0.01%+4,900+19.2%Added
Alliancebernstein L.P.30,556$1.83M0.00%+1,084+3.7%Added
Axiom Investors LLC30,881$1.85M0.02%+23,850+339.2%Added
Mutual of America Capital Management LLC30,982$1.85M0.02%−10,532−25.4%Reduced
Guggenheim Capital LLC31,570$1.89M0.01%−9,535−23.2%Reduced
D. E. Shaw & Co., Inc.33,086$1.98M0.00%−6,387−16.2%Reduced
Ikarian Capital, LLC34,361$2.06M0.56%+34,361New
Dimensional Fund Advisors LP35,567$2.13M0.00%+9,500+36.4%Added
Janus Henderson Group PLC37,917$2.27M0.00%−74−0.2%Reduced
Parallax Volatility Advisers, L.P.39,392$2.36M0.06%+39,392New
Algert Global LLC40,929$2.45M0.10%−19,375−32.1%Reduced
Mackenzie Financial Corp41,485$2.48M0.00%+41,485New
Picton Mahoney Asset Management41,521$2.49M0.12%−27,556−39.9%Reduced
Granahan Investment Management Inc42,241$2.53M0.08%−33,879−44.5%Reduced
Public Employees Retirement System of Ohio42,322$2.53M0.01%+1,700+4.2%Added
Erste Asset Management GmbH42,000$2.64M0.04%+18,000+75.0%Added
Treasurer of the State of North Carolina44,820$2.68M0.01%+1,020+2.3%Added
Simplex Trading, LLC44,954$2.69M0.08%−31,911−41.5%Reduced
Lisanti Capital Growth, LLC46,305$2.77M0.65%−64,695−58.3%Reduced
SG Americas Securities, LLC48,901$2.93M0.03%−125,668−72.0%Reduced
Canada Pension Plan Investment Board49,900$2.99M0.00%−32,400−39.4%Reduced
Velan Capital Investment Management LP50,000$2.99M2.12%00.0%Unchanged
PDT Partners, LLC51,951$3.11M0.34%−13,575−20.7%Reduced
GTS Securities LLC52,047$3.12M0.07%+15,253+41.5%Added
State of New Jersey Common Pension Fund D53,064$3.18M0.01%−8,457−13.7%Reduced
DekaBank Deutsche Girozentrale55,000$3.43M0.01%00.0%Unchanged
Agf Management Ltd58,496$3.50M0.02%−12,228−17.3%Reduced
Allspring Global Investments Holdings, LLC59,275$3.55M0.01%−16,243−21.5%Reduced
Cowen and Company, LLC66,470$3.98M0.26%+66,470New
Nisa Investment Advisors, LLC67,350$4.03M0.03%−1,000−1.5%Reduced
State of Wisconsin Investment Board67,805$4.06M0.01%−14,967−18.1%Reduced
Affinity Asset Advisors, LLC75,000$4.49M0.90%+35,000+87.5%Added
HRT Financial LP75,912$4.54M0.03%+75,912New
Acuta Capital Partners, LLC76,100$4.56M2.56%−168,384−68.9%Reduced
Sawtooth Solutions, LLC78,246$4.68M0.13%−134−0.2%Reduced
Bleakley Financial Group, LLC78,246$4.68M0.15%−134−0.2%Reduced
Lazard Asset Management LLC82,511$4.94M0.01%−33,378−28.8%Reduced
Legal & General Group Plc83,471$5.00M0.00%+1,693+2.1%Added
State Board of Administration of Florida Retirement System84,178$5.04M0.01%+21,542+34.4%Added
Credit Suisse AG85,571$5.12M0.00%−1,442−1.7%Reduced
Envestnet Asset Management Inc86,428$5.17M0.00%+5,971+7.4%Added