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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
256
−59 vs. Q2 2023
Shares held
113.9M
+8.45M (+8.0%) vs. Q2 2023
Total value
$4.34B
−$5.27B (−54.8%) vs. Q2 2023
New holders
47
126 more added
Sold out
106
65 more reduced

2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 256 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ3 2023: $4.34B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2023.

Institutions holding APLS in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
XTX Topco Ltd12,796$486.8K0.08%+12,796New
Allianz Asset Management GmbH13,600$517.3K0.00%−9,000−39.8%Reduced
Xponance, Inc.13,866$527.5K0.01%−181−1.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)14,021$533.4K0.00%+1,310+10.3%Added
Citadel Advisors LLC14,747$561.0K0.00%−513,825−97.2%Reduced
Sippican Capital Advisors15,834$602.3K0.55%+6,930+77.8%Added
Handelsbanken Fonder AB17,200$654.0K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC17,910$681.3K0.00%−52,870−74.7%Reduced
Birchview Capital, LP18,000$684.7K0.58%+6,000+50.0%Added
Intech Investment Management LLC21,307$810.5K0.01%+21,307New
Amalgamated Bank22,185$844.0K0.01%+763+3.6%Added
Seven Eight Capital, LP22,188$844.0K0.10%+22,188New
Wolverine Trading, LLC22,374$851.1K0.01%+22,374New
Teacher Retirement System of Texas23,099$879.0K0.01%+1,203+5.5%Added
Arizona State Retirement System23,211$882.9K0.01%+541+2.4%Added
Virtu Financial LLC23,235$884.0K0.09%+23,235New
Steward Partners Investment Advisory, LLC24,550$933.9K0.01%+23,550+2,355.0%Added
Erste Asset Management GmbH24,000$952.1K0.02%−27,650−53.5%Reduced
Walleye Trading LLC25,480$969.3K0.02%+18,484+264.2%Added
Skandinaviska Enskilda Banken AB (publ)25,581$972.0K0.01%−3,860−13.1%Reduced
Dimensional Fund Advisors LP26,067$991.6K0.00%−105,720−80.2%Reduced
Engineers Gate Manager LP26,361$1.00M0.04%+22,846+650.0%Added
Principal Financial Group Inc26,983$1.03M0.00%−23,973−47.0%Reduced
Brinker Capital Investments, LLC27,396$1.04M0.01%+10,713+64.2%Added
Orion Portfolio Solutions, LLC27,396$1.04M0.01%+10,713+64.2%Added
Alliancebernstein L.P.29,472$1.12M0.00%−135−0.5%Reduced
Aquatic Capital Management LLC29,800$1.13M0.05%+29,800New
Stifel Financial Corp30,034$1.14M0.00%+12,016+66.7%Added
SEI Investments Co32,673$1.24M0.00%−32,662−50.0%Reduced
Frontier Capital Management Co LLC34,600$1.32M0.01%+34,600New
Profund Advisors LLC35,153$1.34M0.07%+18,766+114.5%Added
Russell Investments Group, Ltd.35,471$1.35M0.00%−102,056−74.2%Reduced
GTS Securities LLC36,794$1.40M0.03%+22,465+156.8%Added
Cutler Group LP37,122$1.41M0.23%+36,343+4,665.3%Added
Janus Henderson Group PLC37,991$1.44M0.00%−1,738,914−97.9%Reduced
D. E. Shaw & Co., Inc.39,473$1.50M0.00%−488,338−92.5%Reduced
Affinity Asset Advisors, LLC40,000$1.52M0.50%+30,000+300.0%Added
Public Employees Retirement System of Ohio40,622$1.54M0.01%−4,500−10.0%Reduced
Guggenheim Capital LLC41,105$1.56M0.01%+9,645+30.7%Added
Baird Financial Group, Inc.41,278$1.57M0.00%+2,144+5.5%Added
Mutual of America Capital Management LLC41,514$1.58M0.02%−2,470−5.6%Reduced
Raymond James & Associates42,020$1.60M0.00%−3,530−7.7%Reduced
Cubist Systematic Strategies, LLC42,921$1.63M0.02%+1,742+4.2%Added
Treasurer of the State of North Carolina43,800$1.67M0.01%+230+0.5%Added
General American Investors Co Inc45,000$1.71M0.15%+45,000New
Millennium Management LLC45,129$1.72M0.00%−873,682−95.1%Reduced
Portman Square Capital LLP46,132$1.75M0.24%+46,132New
Velan Capital Investment Management LP50,000$1.90M1.55%+50,000New
Tudor Investment Corp Et Al50,112$1.91M0.03%+42,714+577.4%Added
HSBC Holdings PLC50,544$1.96M0.00%+50,544New
Voloridge Investment Management, LLC54,263$2.06M0.01%−89,139−62.2%Reduced
Manufacturers Life Insurance Company, The54,265$2.06M0.00%−115,408−68.0%Reduced
DekaBank Deutsche Girozentrale55,000$2.15M0.00%+55,000New
LMR Partners LLP57,129$2.17M0.05%+38,693+209.9%Added
Algert Global LLC60,304$2.29M0.11%+32,505+116.9%Added
State of New Jersey Common Pension Fund D61,521$2.34M0.01%+10,328+20.2%Added
State Board of Administration of Florida Retirement System62,636$2.38M0.01%+150+0.2%Added
PDT Partners, LLC65,526$2.49M0.31%+40,416+161.0%Added
Nisa Investment Advisors, LLC68,350$2.60M0.02%+55,759+442.8%Added
Picton Mahoney Asset Management69,077$2.63M0.12%+26,350+61.7%Added
Agf Management Ltd70,724$2.69M0.02%+30,262+74.8%Added
Allspring Global Investments Holdings, LLC75,518$2.87M0.01%−53,137−41.3%Reduced
Granahan Investment Management Inc76,120$2.90M0.10%−37,655−33.1%Reduced
Simplex Trading, LLC76,865$2.92M0.11%+854+1.1%Added
Sawtooth Solutions, LLC78,380$2.98M0.10%−307−0.4%Reduced
Bleakley Financial Group, LLC78,380$2.98M0.11%−307−0.4%Reduced
Thrivent Financial for Lutherans79,461$3.02M0.01%+79,461New
Envestnet Asset Management Inc80,457$3.06M0.00%+59,152+277.6%Added
Legal & General Group Plc81,778$3.11M0.00%−2,373−2.8%Reduced
Voya Investment Management LLC82,167$3.13M0.00%−139,247−62.9%Reduced
Canada Pension Plan Investment Board82,300$3.13M0.00%00.0%Unchanged
State of Wisconsin Investment Board82,772$3.15M0.01%+5,952+7.7%Added
Credit Suisse AG87,013$3.31M0.00%−6,870−7.3%Reduced
California State Teachers Retirement System94,269$3.59M0.01%−10,218−9.8%Reduced
Comerica Bank96,179$3.66M0.02%+96,179New
Banque Pictet & Cie SA102,242$3.89M0.05%−4,893−4.6%Reduced
Jacobs Levy Equity Management, Inc109,508$4.17M0.02%+109,508New
Lisanti Capital Growth, LLC111,000$4.22M0.67%+65,505+144.0%Added
Lazard Asset Management LLC115,889$4.41M0.01%+104,805+945.6%Added
Citigroup Inc116,896$4.45M0.01%+36,911+46.1%Added
Royal Bank of Canada118,664$4.51M0.00%−21,821−15.5%Reduced
The PNC Financial Services Group, Inc.119,740$4.55M0.00%−2,611−2.1%Reduced
Eversept Partners, LP122,643$4.67M0.52%+66,194+117.3%Added
Rhumbline Advisers132,294$5.03M0.01%−579−0.4%Reduced
Walleye Capital LLC133,983$5.10M0.07%+76,074+131.4%Added
UBS Asset Management Americas Inc145,946$5.55M0.00%+46,142+46.2%Added
Twinbeech Capital LP150,229$5.71M0.11%+150,229New
Wells Fargo & Company155,707$5.92M0.00%+63,512+68.9%Added
Marshall Wace, LLP169,294$6.44M0.01%−173,058−50.5%Reduced
SG Americas Securities, LLC174,569$6.64M0.09%+73,458+72.7%Added
Swiss National Bank179,200$6.82M0.01%+3,500+2.0%Added
Driehaus Capital Management LLC181,324$6.90M0.09%−166,052−47.8%Reduced
Ally Bridge Group (NY) LLC181,805$6.92M8.12%+181,805New
California Public Employees Retirement System183,844$6.99M0.01%+1,656+0.9%Added
Ensign Peak Advisors, Inc185,566$7.06M0.02%+154,686+500.9%Added
Farallon Capital Management, L.L.C.194,053$7.38M0.04%+154,000+384.5%Added
Rafferty Asset Management, LLC214,161$8.15M0.05%+121,893+132.1%Added
Rhenman & Partners Asset Management AB215,000$8.18M0.88%+25,000+13.2%Added
Group One Trading, L.P.226,684$8.62M0.34%+207,866+1,104.6%Added
BNP Paribas Arbitrage, SA236,355$8.99M0.02%+177,694+302.9%Added