Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 244
- −4 vs. Q3 2022
- Shares held
- 100.5M
- +3.04M (+3.1%) vs. Q3 2022
- Total value
- $5.20B
- −$1.46B (−21.9%) vs. Q3 2022
- New holders
- 36
- 96 more added
- Sold out
- 40
- 83 more reduced
2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Regent Investment Management LLC | 21,309 | $1.10M | 0.30% | 00.0% | Unchanged |
| SG3 Management, LLC | 22,000 | $1.14M | 0.70% | −18,000−45.0% | Reduced |
| ProShare Advisors LLC | 22,637 | $1.17M | 0.00% | +1,569+7.4% | Added |
| Arizona State Retirement System | 24,801 | $1.28M | 0.01% | +1,643+7.1% | Added |
| Amundi | 25,838 | $1.29M | 0.00% | −4,570−15.0% | Reduced |
| EFG Asset Management (North America) Corp. | 25,377 | $1.31M | 0.29% | −1,955−7.2% | Reduced |
| Mirabella Financial Services LLP | 25,326 | $1.31M | 0.12% | +25,326 | New |
| Axiom Investors LLC | 25,348 | $1.31M | 0.03% | −6,627−20.7% | Reduced |
| Teacher Retirement System of Texas | 27,002 | $1.40M | 0.01% | −860−3.1% | Reduced |
| Mutual of America Capital Management LLC | 28,089 | $1.45M | 0.02% | +378+1.4% | Added |
| State Board of Administration of Florida Retirement System | 28,116 | $1.45M | 0.00% | +150+0.5% | Added |
| Clough Capital Partners L P | 28,609 | $1.48M | 0.15% | −14,000−32.9% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 30,846 | $1.59M | 0.01% | −6,208−16.8% | Reduced |
| Adage Capital Partners GP, L.L.C. | 31,000 | $1.60M | 0.00% | +31,000 | New |
| SG Americas Securities, LLC | 31,382 | $1.62M | 0.02% | +3,520+12.6% | Added |
| International Biotechnology Trust PLC | 31,700 | $1.64M | 0.51% | +31,700 | New |
| Susquehanna International Group, LLP | 31,732 | $1.64M | 0.00% | −26,128−45.2% | Reduced |
| Parallax Volatility Advisers, L.P. | 31,880 | $1.65M | 0.04% | −45,273−58.7% | Reduced |
| Algert Global LLC | 33,231 | $1.72M | 0.10% | 00.0% | Unchanged |
| Picton Mahoney Asset Management | 33,526 | $1.73M | 0.09% | +2,676+8.7% | Added |
| BNP Paribas Arbitrage, SA | 36,196 | $1.87M | 0.00% | −79,166−68.6% | Reduced |
| Erste Asset Management GmbH | 37,000 | $1.91M | 0.04% | 00.0% | Unchanged |
| HighVista Strategies LLC | 39,111 | $2.02M | 1.20% | −14,431−27.0% | Reduced |
| Baird Financial Group, Inc. | 39,477 | $2.04M | 0.01% | +7,533+23.6% | Added |
| Dimensional Fund Advisors LP | 41,007 | $2.12M | 0.00% | −41,587−50.4% | Reduced |
| American International Group, Inc. | 44,361 | $2.29M | 0.02% | −161−0.4% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 45,179 | $2.34M | 0.01% | +2,291+5.3% | Added |
| Guggenheim Capital LLC | 48,807 | $2.52M | 0.02% | +13,288+37.4% | Added |
| DekaBank Deutsche Girozentrale | 50,000 | $2.53M | 0.01% | 00.0% | Unchanged |
| MetLife Investment Management | 49,665 | $2.57M | 0.02% | 00.0% | Unchanged |
| Group One Trading, L.P. | 50,823 | $2.63M | 0.09% | +50,823 | New |
| First Trust Advisors LP | 52,780 | $2.73M | 0.00% | +27,551+109.2% | Added |
| Neuberger Berman Group LLC | 55,498 | $2.87M | 0.00% | +11,164+25.2% | Added |
| Lisanti Capital Growth, LLC | 55,695 | $2.88M | 0.39% | −141,595−71.8% | Reduced |
| Ameriprise Financial Inc | 57,640 | $2.98M | 0.00% | +1,099+1.9% | Added |
| State of New Jersey Common Pension Fund D | 57,903 | $2.99M | 0.01% | +3,069+5.6% | Added |
| Polar Asset Management Partners Inc. | 58,310 | $3.02M | 0.04% | −324,290−84.8% | Reduced |
| Nomura Holdings Inc | 59,465 | $3.07M | 0.03% | +3,295+5.9% | Added |
| The PNC Financial Services Group, Inc. | 60,955 | $3.15M | 0.00% | +3,009+5.2% | Added |
| Brookfield Asset Management Inc. | 66,226 | $3.42M | 0.01% | +5,996+10.0% | Added |
| Tekla Capital Management LLC | 66,426 | $3.43M | 0.13% | −199,650−75.0% | Reduced |
| Comerica Bank | 66,230 | $3.44M | 0.03% | +66,230 | New |
| Woodline Partners LP | 70,651 | $3.65M | 0.05% | +70,651 | New |
| Russell Investments Group, Ltd. | 71,875 | $3.72M | 0.01% | −16,265−18.5% | Reduced |
| Principal Financial Group Inc | 72,982 | $3.77M | 0.00% | +47,936+191.4% | Added |
| UBS Asset Management Americas Inc | 75,086 | $3.88M | 0.00% | +5,928+8.6% | Added |
| Pier Capital, LLC | 75,217 | $3.89M | 0.64% | +19,833+35.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 76,881 | $3.98M | 0.02% | +71,567+1,346.8% | Added |
| Credit Suisse AG | 76,908 | $3.98M | 0.00% | +380.0% | Added |
| Teachers Retirement System of the State of Kentucky | 78,486 | $4.06M | 0.04% | −25,316−24.4% | Reduced |
| Legal & General Group Plc | 80,394 | $4.16M | 0.00% | −248−0.3% | Reduced |
| Citigroup Inc | 82,100 | $4.25M | 0.01% | −15,732−16.1% | Reduced |
| Canada Pension Plan Investment Board | 82,300 | $4.26M | 0.01% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 82,830 | $4.27M | 0.00% | −10,254−11.0% | Reduced |
| DAFNA Capital Management LLC | 83,446 | $4.31M | 1.22% | +17,500+26.5% | Added |
| Lazard Asset Management LLC | 84,820 | $4.39M | 0.01% | +38,724+84.0% | Added |
| State of Wisconsin Investment Board | 88,158 | $4.56M | 0.01% | +6,968+8.6% | Added |
| Putnam Investments LLC | 97,560 | $5.04M | 0.01% | −8,243−7.8% | Reduced |
| Bank of Montreal | 100,931 | $5.22M | 0.00% | −28,408−22.0% | Reduced |
| Royal Bank of Canada | 103,316 | $5.34M | 0.00% | +29,097+39.2% | Added |
| New York State Common Retirement Fund | 104,420 | $5.40M | 0.01% | −45,534−30.4% | Reduced |
| Man Group plc | 105,784 | $5.47M | 0.02% | −37,601−26.2% | Reduced |
| Alliancebernstein L.P. | 111,100 | $5.74M | 0.00% | −41,824−27.3% | Reduced |
| California State Teachers Retirement System | 113,909 | $5.89M | 0.01% | +3,549+3.2% | Added |
| Allspring Global Investments Holdings, LLC | 126,793 | $6.56M | 0.01% | +2,122+1.7% | Added |
| Rhumbline Advisers | 130,601 | $6.75M | 0.01% | +7,412+6.0% | Added |
| UBS Group AG | 131,897 | $6.82M | 0.00% | +117,258+801.0% | Added |
| Eagle Asset Management Inc | 136,114 | $6.84M | 0.04% | −5,103−3.6% | Reduced |
| AXA S.A. | 145,704 | $7.53M | 0.03% | −784−0.5% | Reduced |
| Sessa Capital IM, L.P. | 149,000 | $7.70M | 0.47% | 00.0% | Unchanged |
| Sectoral Asset Management Inc | 152,340 | $7.88M | 1.52% | +28,350+22.9% | Added |
| Eversept Partners, LP | 154,796 | $8.00M | 0.76% | +154,796 | New |
| Banque Pictet & Cie SA | 158,925 | $8.22M | 0.09% | −10,046−5.9% | Reduced |
| Ensign Peak Advisors, Inc | 163,430 | $8.45M | 0.02% | +141,100+631.9% | Added |
| Rafferty Asset Management, LLC | 164,104 | $8.49M | 0.07% | +61,532+60.0% | Added |
| Voya Investment Management LLC | 165,306 | $8.55M | 0.01% | −7,375−4.3% | Reduced |
| Lombard Odier Asset Management (Switzerland) SA | 170,353 | $8.81M | 0.70% | +40,776+31.5% | Added |
| 683 Capital Management, LLC | 175,000 | $9.05M | 0.82% | +175,000 | New |
| Prudential Financial Inc | 177,381 | $9.17M | 0.02% | −3,993−2.2% | Reduced |
| Saturn V Capital Management LLC | 212,329 | $9.41M | 7.81% | +212,329 | New |
| Bleakley Financial Group, LLC | 182,438 | $9.43M | 0.34% | +182,438 | New |
| Granahan Investment Management Inc | 182,508 | $9.44M | 0.29% | +45,773+33.5% | Added |
| Renaissance Technologies LLC | 187,413 | $9.69M | 0.01% | −157,700−45.7% | Reduced |
| California Public Employees Retirement System | 191,964 | $9.93M | 0.01% | +22,282+13.1% | Added |
| Rhenman & Partners Asset Management AB | 200,000 | $10.3M | 1.08% | −20,000−9.1% | Reduced |
| Fred Alger Management, LLC | 206,263 | $10.7M | 0.06% | +71,961+53.6% | Added |
| Swiss National Bank | 212,200 | $11.0M | 0.01% | +10,100+5.0% | Added |
| Acuta Capital Partners, LLC | 217,500 | $11.2M | 6.92% | −336,500−60.7% | Reduced |
| Tri Locum Partners LP | 221,897 | $11.5M | 5.07% | +221,897 | New |
| Barclays PLC | 227,347 | $11.8M | 0.01% | +94,198+70.7% | Added |
| American Century Companies Inc | 230,824 | $11.9M | 0.01% | +215,553+1,411.5% | Added |
| Nicholas Investment Partners, LP | 248,283 | $12.8M | 1.12% | +53,770+27.6% | Added |
| Balyasny Asset Management LLC | 256,341 | $13.3M | 0.05% | +209,076+442.3% | Added |
| Deutsche Bank AG | 263,177 | $13.6M | 0.01% | −304,568−53.6% | Reduced |
| TD Asset Management Inc | 271,620 | $14.0M | 0.02% | −7,096−2.5% | Reduced |
| Candriam Luxembourg S.C.A. | 278,507 | $14.4M | 0.10% | −65,000−18.9% | Reduced |
| Driehaus Capital Management LLC | 293,545 | $15.2M | 0.23% | −564,586−65.8% | Reduced |
| Morgan Stanley | 299,883 | $15.5M | 0.00% | +76,607+34.3% | Added |
| Ghost Tree Capital, LLC | 300,000 | $15.5M | 6.62% | +25,000+9.1% | Added |
| Kynam Capital Management, LP | 300,000 | $15.5M | 2.38% | +300,000 | New |