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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
187
+8 vs. Q3 2021
Shares held
81.0M
+11.5M (+16.6%) vs. Q3 2021
Total value
$3.83B
+$1.54B (+67.1%) vs. Q3 2021
New holders
44
73 more added
Sold out
36
53 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 187 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2021: $3.83B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding APLS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
State of New Jersey Common Pension Fund D63,934$3.02M0.01%+20,250+46.4%Added
New York State Common Retirement Fund65,814$3.11M0.00%+18,810+40.0%Added
Assenagon Asset Management S.A.67,282$3.18M0.01%+67,282New
Morgan Stanley67,659$3.20M0.00%−109,637−61.8%Reduced
Susquehanna International Group, LLP68,749$3.25M0.00%−40,661−37.2%Reduced
Legal & General Group Plc69,167$3.27M0.00%+11,268+19.5%Added
Private Advisor Group, LLC73,242$3.46M0.03%−72,626−49.8%Reduced
Rhumbline Advisers73,929$3.50M0.00%+4,534+6.5%Added
Voloridge Investment Management, LLC76,162$3.60M0.02%−272,546−78.2%Reduced
Alliancebernstein L.P.80,000$3.78M0.00%+800+1.0%Added
Granahan Investment Management Inc83,601$3.95M0.08%+83,601New
Verition Fund Management LLC84,493$4.00M0.05%+84,493New
Ensign Peak Advisors, Inc85,589$4.05M0.01%+82,647+2,809.2%Added
Polar Asset Management Partners Inc.86,600$4.09M0.05%+58,600+209.3%Added
State of Wisconsin Investment Board95,700$4.53M0.01%+5,700+6.3%Added
Neuberger Berman Group LLC101,123$4.68M0.00%+36,927+57.5%Added
Jane Street Group, LLC100,711$4.76M0.01%+84,768+531.7%Added
Lisanti Capital Growth, LLC103,425$4.89M0.71%+103,425New
California State Teachers Retirement System103,701$4.90M0.01%+19,084+22.6%Added
Voya Investment Management LLC103,876$4.91M0.01%+78,732+313.1%Added
Royal Bank of Canada105,190$4.97M0.00%+13,309+14.5%Added
Russell Investments Group, Ltd.107,951$5.10M0.01%−16,483−13.2%Reduced
UBS Group AG109,387$5.17M0.00%−87,495−44.4%Reduced
Walleye Capital LLC115,133$5.44M0.18%+115,133New
Schonfeld Strategic Advisors LLC118,558$5.61M0.05%+107,258+949.2%Added
Citigroup Inc119,688$5.66M0.01%+49,396+70.3%Added
Integral Health Asset Management, LLC120,000$5.67M1.58%−70,000−36.8%Reduced
Frontier Capital Management Co LLC123,490$5.84M0.05%−152,420−55.2%Reduced
Rafferty Asset Management, LLC125,910$5.95M0.03%+36,711+41.2%Added
Balyasny Asset Management LLC128,514$6.08M0.03%−54,633−29.8%Reduced
Privium Fund Management B.V.127,616$6.12M1.22%+127,616New
Clough Capital Partners L P131,749$6.23M0.42%−6,000−4.4%Reduced
Hennion & Walsh Asset Management, Inc.136,760$6.47M0.32%−45,445−24.9%Reduced
Teachers Retirement System of the State of Kentucky138,931$6.57M0.06%+7,741+5.9%Added
Asymmetry Capital Management, L.P.139,445$6.59M3.50%+139,445New
Barclays PLC145,248$6.87M0.00%+112,555+344.3%Added
TD Asset Management Inc161,045$7.61M0.01%+41,381+34.6%Added
Ameriprise Financial Inc166,688$7.88M0.00%−36,024−17.8%Reduced
Banque Pictet & Cie SA168,489$7.97M0.06%+151,606+898.0%Added
Swiss National Bank168,900$7.99M0.00%+35,500+26.6%Added
SG Americas Securities, LLC177,734$8.40M0.06%−6,280−3.4%Reduced
Prudential Financial Inc180,270$8.74M0.01%+8,875+5.2%Added
Bank of Montreal179,681$8.77M0.00%−73,847−29.1%Reduced
Tekla Capital Management LLC195,820$9.26M0.30%00.0%Unchanged
Caption Management, LLC220,000$10.4M0.65%+198,557+926.0%Added
Pier Capital, LLC221,901$10.5M1.11%+65,870+42.2%Added
Nuveen Asset Management, LLC256,441$10.8M0.00%−9,803−3.7%Reduced
Driehaus Capital Management LLC262,897$12.4M0.13%−12,655−4.6%Reduced
Bank of America Corp274,906$13.0M0.00%−5,066−1.8%Reduced
Bank of New York Mellon Corp298,193$14.1M0.00%+28,709+10.7%Added
Jacobs Levy Equity Management, Inc310,594$14.7M0.10%−203,047−39.5%Reduced
Millennium Management LLC312,002$14.8M0.02%−93,380−23.0%Reduced
Tri Locum Partners LP318,269$15.0M6.03%+318,269New
Ghost Tree Capital, LLC325,000$15.4M5.88%+125,000+62.5%Added
Deutsche Bank AG338,753$16.0M0.01%+47,744+16.4%Added
Deerfield Management Company, L.P. (Series C)343,213$16.2M0.34%+343,213New
UBS Asset Management Americas Inc373,674$17.7M0.01%+169,684+83.2%Added
Lombard Odier Asset Management (Switzerland) SA423,676$20.0M1.28%+216,930+104.9%Added
Rhenman & Partners Asset Management AB430,000$20.6M1.37%−131,269−23.4%Reduced
Goldman Sachs Group Inc498,082$23.5M0.01%−525,088−51.3%Reduced
Acuta Capital Partners, LLC535,000$25.3M10.63%+459,500+608.6%Added
Fiduciary Trust Co564,841$26.7M0.44%−350.0%Reduced
Charles Schwab Investment Management Inc591,914$28.0M0.01%+73,103+14.1%Added
Cormorant Asset Management, LP625,000$29.6M1.76%−300,000−32.4%Reduced
Norges Bank640,167$30.3M0.01%+129,989+25.5%Added
Pictet Asset Management SA646,359$30.6M0.03%+646,359New
Bellevue Group AG650,591$30.8M0.32%+602,591+1,255.4%Added
Candriam Luxembourg S.C.A.694,425$32.8M0.21%+439,395+172.3%Added
Northern Trust Corp743,867$35.2M0.01%+81,181+12.3%Added
Citadel Advisors LLC953,731$45.1M0.05%−904,701−48.7%Reduced
Logos Global Management LP1,000,000$47.3M4.88%−450,000−31.0%Reduced
Macquarie Group Ltd1,291,783$61.1M0.05%+171,693+15.3%Added
Geode Capital Management, LLC1,352,829$64.0M0.01%+164,437+13.8%Added
Perceptive Advisors LLC1,451,700$68.6M1.06%+836,700+136.0%Added
Victory Capital Management Inc1,565,977$74.0M0.07%−204,830−11.6%Reduced
JPMorgan Chase & Co1,587,878$75.1M0.01%+54,736+3.6%Added
FMR LLC1,614,859$76.4M0.01%00.0%Unchanged
Jennison Associates LLC1,862,157$88.0M0.06%−216,688−10.4%Reduced
RTW Investments, LP1,990,404$94.1M1.37%+1,990,404New
Octagon Capital Advisors LP2,020,911$95.5M18.59%+425,000+26.6%Added
State Street Corp2,719,368$128.6M0.01%−106,827−3.8%Reduced
EcoR1 Capital, LLC4,033,882$190.7M6.11%+4,033,882New
Price T Rowe Associates Inc5,298,491$250.5M0.02%+491,414+10.2%Added
BlackRock Inc.5,865,712$277.3M0.01%+399,521+7.3%Added
Vanguard Group Inc7,917,099$374.3M0.01%+1,164,814+17.3%Added
Avoro Capital Advisors LLC8,555,555$404.5M6.89%+3,555,555+71.1%Added
Wellington Management Group LLP12,330,653$583.0M0.09%+1,159,081+10.4%Added
AJU IB Investment Co., Ltd.0$00.00%−624,962−100.0%Sold out
Franklin Resources Inc0$00.00%−610,339−100.0%Sold out
Arrowstreet Capital, Limited Partnership0$00.00%−418,539−100.0%Sold out
Two Sigma Investments, LP0$00.00%−362,204−100.0%Sold out
Ikarian Capital, LLC0$00.00%−347,545−100.0%Sold out
Natixis0$00.00%−216,500−100.0%Sold out
Jefferies Group LLC0$00.00%−165,038−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−150,703−100.0%Sold out
LMR Partners LLP0$00.00%−121,111−100.0%Sold out
Duality Advisers, LP0$00.00%−111,100−100.0%Sold out
Alps Advisors Inc0$00.00%−106,632−100.0%Sold out
Kingdon Capital Management, L.L.C.0$00.00%−100,000−100.0%Sold out
SG3 Management, LLC0$00.00%−100,000−100.0%Sold out