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OrbiMed Advisors LLC

In the past year, 6 open-market purchase filings worth $85.9M and 6 sale filings worth $63.0M.

Current role at each company

Show 39 more companies

Open-market trades in the past year

Open-market purchases (P) and sales (S) filed in the last 365 days, not counting derivative securities or duplicate filings. Values leave out price outliers.

Bought
$85.9M
6 filings
Sold
$63.0M
6 filings
Net
+$22.9M
Bought minus sold
Companies
9
With open-market trades

Trades

Every Form 4 that lists OrbiMed Advisors LLC as a reporting owner, including filings made jointly with others, grouped by company. Each row adds up one type of transaction in one filing. Only open-market purchases (P) and sales (S) are shown by default.

ETRA Electra Therapeutics, Inc.

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 23, 2026 (view filing)5:29 PM ETSep 212 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.33M$15.00+$20.0M+313.8%1.76M after2 lots

BLSM BlossomHill Therapeutics, Inc.

Director1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 12, 2026 (view filing)4:43 PM ETAug 102 daysOrbiMed Advisors LLC and 1 otherDirectorPPurchase+625.0K$16.00+$10.0M+29.9%2.71M after

BRVE Braveheart Bio, Inc.

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 11, 2026 (view filing)5:27 PM ETAug 74 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.94M$18.00+$34.9MNew position273.3K after2 lots

SCTX Scribe Therapeutics, Inc.

Director1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 29, 2026 (view filing)6:47 PM ETJul 272 daysOrbiMed Advisors LLC and 1 otherDirectorPPurchase+1.00M$15.00+$15.0M+286.7%1.35M after

SION Sionna Therapeutics, Inc.

Director11 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Feb 10, 2025 (view filing)4:28 PM ETFeb 10Same dayOrbiMed Advisors LLC and 1 otherDirectorPPurchase+550.0K$18.00+$9.90M+17.4%3.70M afterDuplicate filing
Nov 26, 2025 (view filing)6:45 PM ETNov 24-262 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−108.1K$44.55−$4.81M−2.9%3.60M after3 lots10b5-1Duplicate filing
Dec 19, 2025 (view filing)7:29 PM ETDec 17-192 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−1.88K$44.49−$83.4K−0.1%3.60M after3 lots10b5-1Duplicate filing
Dec 29, 2025 (view filing)8:44 PM ETDec 245 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−33.4K$44.55−$1.49M−0.9%3.56M after10b5-1Duplicate filing
Feb 4, 2026 (view filing)7:39 PM ETFeb 2-32 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−31.0K$44.58−$1.38M−0.9%3.53M after2 lots10b5-1Duplicate filing
Apr 16, 2026 (view filing)7:03 PM ETApr 14-162 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−510.6K$44.94−$22.9M−14.5%3.02M after3 lots10b5-1Duplicate filing
Apr 21, 2026 (view filing)8:40 PM ETApr 17-184 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−55.3K$44.67−$2.47M−1.8%2.96M after2 lots10b5-1Duplicate filing
May 11, 2026 (view filing)6:58 PM ETMay 7-114 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−293.0K$45.62−$13.4M−9.9%2.67M after3 lots10b5-1Duplicate filing
May 29, 2026 (view filing)8:57 PM ETMay 272 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−101$44.49−$4.49K0.0%2.67M after10b5-1Duplicate filing
Jul 2, 2026 (view filing)4:42 PM ETJun 302 daysOrbiMed Advisors LLC and 1 otherDirectorSSale−115.8K$45.50−$5.27M−4.3%2.56M after10b5-1

See all 11 trades at SION

ELVN Enliven Therapeutics, Inc.

10% Owner5 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 16, 2021 (view filing)4:27 PM ETJul 16Same dayOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.67M$6.00+$10.0MNew position1.67M after
Jul 23, 2021 (view filing)5:30 PM ETJul 167 daysOrbiMed Advisors LLC and 1 otherDirector, 10% OwnerPPurchase+1.67M$6.00+$10.0M+65.8%4.20M afterAmendedDuplicate filing
May 20, 2024 (view filing)5:00 PM ETMay 164 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerSSale−1.03M$22.14−$22.9M−11.9%7.66M after2 lotsDuplicate filing
Jun 17, 2026 (view filing)7:45 PM ETJun 152 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−281.4K$45.02−$12.7M−3.7%7.39M after2 lots
Jun 24, 2026 (view filing)7:19 PM ETJun 222 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−860.1K$45.36−$39.0M−11.6%6.56M after4 lots

STTK Shattuck Labs, Inc.

Director3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 2, 2025 (view filing)9:52 PM ETAug 258 daysLateOrbiMed Advisors LLC and 2 othersDirectorPPurchase+6.31M$0.8677+$5.47MNew position1.05M after2 lots
Sep 2, 2025 (view filing)9:52 PM ETAug 258 daysLateOrbiMed Advisors LLC and 2 othersDirectorPPurchase+30.6M–––3.07M afterDerivative4 lotsDuplicate filing
Jun 15, 2026 (view filing)6:12 PM ETJun 114 daysOrbiMed Advisors LLC and 2 othersDirectorPPurchase+1.25M–––5.30M afterDerivative2 lotsDuplicate filing

QTTB Q32 Bio Inc.

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 1, 2026 (view filing)9:13 PM ETMay 284 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.88M$8.00+$15.0MNew position625.0K after2 lotsDuplicate filing

TRAW Traws Pharma, Inc.

10% Owner3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jan 27, 2025 (view filing)7:03 PM ETDec 29, 202429 daysLateOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+192.7K–––96.3K afterDerivative2 lotsDuplicate filing
Apr 28, 2026 (view filing)9:41 PM ETApr 1612 daysLateOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+597.7K$1.67+$998.2K+98.7%1.20M after
Apr 28, 2026 (view filing)9:41 PM ETApr 1612 daysLateOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+2.99M–––1.79M afterDerivative3 lots

PRLD Prelude Therapeutics Inc

Director, 10% Owner2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
May 24, 2023 (view filing)5:09 PM ETMay 222 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+869.6K$5.75+$5.00M+9.4%10.1M afterDuplicate filing
Apr 23, 2026 (view filing)6:48 PM ETApr 212 daysOrbiMed Advisors LLC and 3 othersDirector, 10% OwnerPPurchase+2.82M$4.44+$12.5MNew position1.13M after2 lotsDuplicate filing

IMA ImageneBio, Inc.

Director2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 24, 2022 (view filing)5:39 PM ETJun 22-242 daysOrbiMed Advisors LLC and 2 othersDirectorPPurchase−252.2K$4.47−$1.13M−10.7%2.10M after4 lotsDuplicate filing
Apr 16, 2026 (view filing)7:23 PM ETApr 142 daysOrbiMed Advisors LLC and 2 othersDirectorPPurchase+721.3K–––384.7K afterDerivative2 lotsDuplicate filing

ACET Adicet Bio, Inc.

10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 29, 2023 (view filing)4:46 PM ETJun 272 daysOrbiMed Advisors LLC and 8 othersDirector, 10% OwnerPPurchase+875.0K$2.09+$1.83MNew position748.1K after4 lotsDuplicate filing
Jan 26, 2024 (view filing)7:14 PM ETJan 251 dayOrbiMed Advisors LLC and 7 othersDirector, 10% OwnerPPurchase+3.13M$2.40+$7.50MNew position1.26M after3 lotsDuplicate filing
Oct 10, 2025 (view filing)8:06 PM ETOct 82 daysOrbiMed Advisors LLC and 7 others10% OwnerPPurchase+5.00M$1.00+$5.00MNew position4.49M after2 lots
Apr 9, 2026 (view filing)5:38 PM ETApr 7-82 daysOrbiMed Advisors LLC and 7 others10% OwnerSSale−104.7K$6.45−$674.8K−100.0%0 after4 lots

PMVP PMV Pharmaceuticals, Inc.

10% Owner5 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Mar 31, 2022 (view filing)5:30 PM ETMar 29-312 daysOrbiMed Advisors LLC and 3 others10% OwnerSSale−474.5K$21.63−$10.3M−100.0%0 after3 lots
May 31, 2022 (view filing)4:36 PM ETMay 265 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−26.3K$15.93−$418.2K−23.0%87.8K after
Nov 24, 2023 (view filing)4:38 PM ETNov 222 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−87.8K$2.23−$195.8K−100.0%0 after
Sep 12, 2025 (view filing)5:09 PM ETSep 102 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−500.0K$1.80−$900.0K−7.7%5.98M after
Oct 27, 2025 (view filing)5:19 PM ETOct 234 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−1.00M$1.52−$1.52M−16.7%4.98M after

CRVS Corvus Pharmaceuticals, Inc.

Director, 10% Owner3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 22, 2021 (view filing)5:27 PM ETSep 202 daysOrbiMed Advisors LLC and 1 otherDirector, 10% OwnerSSaleCommon Stock, $0.0001 par value−1.11M$6.09−$6.76M−13.8%6.94M afterDuplicate filing
May 8, 2024 (view filing)8:28 PM ETMay 62 daysOrbiMed Advisors LLC and 1 otherDirector, 10% OwnerPPurchase+2.84M$1.73+$2.50M–1.40M afterDerivative2 lots
Jul 1, 2025 (view filing)9:23 PM ETJun 274 daysOrbiMed Advisors LLC and 1 otherDirector, 10% OwnerSSale−1.18M$4.16−$4.89M−14.1%7.17M after

PASG Passage BIO, Inc.

10% Owner15 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jan 13, 2022 (view filing)7:37 PM ETJan 11-132 daysOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+150.0K$5.61+$841.1K+2.5%6.10M after3 lots
Jan 20, 2022 (view filing)6:03 PM ETJan 14-196 daysLateOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+168.3K$5.38+$905.2K+2.8%6.27M after3 lots
May 5, 2022 (view filing)5:11 PM ETJan 20105 daysOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+50.8K$5.00+$254.0K+0.8%6.32M afterAmended
May 5, 2022 (view filing)5:23 PM ETMay 3-42 daysOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+525.0K$1.94+$1.02M+8.3%6.84M after2 lots
Jun 29, 2023 (view filing)4:42 PM ETJun 27-282 daysOrbiMed Advisors LLC and 1 other10% OwnerPPurchase+1.19M$0.84+$1.00M+17.4%8.03M after2 lots
Sep 18, 2024 (view filing)6:38 PM ETSep 16-182 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−200.1K$0.7332−$146.7K−2.5%7.83M after3 lots
Sep 23, 2024 (view filing)4:51 PM ETSep 194 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−39.3K$0.71−$27.9K−0.5%7.79M after
Dec 6, 2024 (view filing)7:07 PM ETDec 4-62 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−97.1K$0.7965−$77.3K−1.2%7.70M after2 lots
Dec 11, 2024 (view filing)5:32 PM ETDec 9-112 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−62.3K$0.8348−$52.0K−0.8%7.64M after3 lots
Dec 26, 2024 (view filing)4:34 PM ETDec 206 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−230.3K$0.60−$138.2K−3.0%7.40M after

See all 15 trades at PASG

NPCE NeuroPace Inc

10% Owner7 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Oct 4, 2023 (view filing)5:36 PM ETOct 2-32 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−8.31K$9.07−$75.4K−0.2%4.00M after2 lots
Apr 15, 2024 (view filing)5:25 PM ETApr 11-124 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−485.0K$14.49−$7.03M−12.1%3.52M after2 lots
Apr 18, 2024 (view filing)5:10 PM ETApr 16-182 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−17.0K$14.02−$238.2K−0.5%3.50M after3 lots
Apr 23, 2024 (view filing)6:38 PM ETApr 19-234 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−64.7K$14.12−$913.1K−1.8%3.44M after3 lots
Apr 26, 2024 (view filing)5:01 PM ETApr 242 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−1.78K$14.06−$25.0K−0.1%3.44M after
May 3, 2024 (view filing)5:16 PM ETMay 1-32 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−29.2K$14.02−$409.4K−0.9%3.41M after3 lots
May 16, 2025 (view filing)5:26 PM ETMay 142 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−168.1K$15.85−$2.67M−4.9%3.24M after2 lots

XTNT Xtant Medical Holdings, Inc.

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 14, 2025 (view filing)7:14 PM ETApr 104 daysOrbiMed Advisors LLC and 1 other10% OwnerSSale−73.1M$0.42−$30.7M−100.0%0 after2 lots

CMPX Compass Therapeutics, Inc.

Director, 10% Owner5 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Nov 8, 2021 (view filing)9:06 PM ETNov 44 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+5.36M$3.50+$18.8MNew position3.57M after2 lotsDuplicate filing
May 10, 2022 (view filing)6:21 PM ETMay 6-104 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+125.4K$1.57+$197.3K+0.9%14.6M after3 lotsDuplicate filing
May 13, 2022 (view filing)5:45 PM ETMay 11-132 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+192.5K$2.18+$420.5K+1.3%14.8M after3 lotsDuplicate filing
Nov 10, 2022 (view filing)4:44 PM ETNov 82 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+402.0K$3.21+$1.29M+2.7%15.2M afterDuplicate filing
Apr 11, 2025 (view filing)7:24 PM ETApr 92 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerSSale−3.57M$1.59−$5.68M−100.0%0 afterDuplicate filing

EWTX Edgewise Therapeutics, Inc.

Director, 10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
May 20, 2022 (view filing)4:38 PM ETMay 182 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+138.0K$7.21+$995.0K+1.0%13.5M afterDuplicate filing
Sep 16, 2022 (view filing)4:31 PM ETSep 16Same dayOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+484.5K$10.32+$5.00M+3.6%14.0M afterDuplicate filing
Jan 25, 2024 (view filing)4:28 PM ETJan 232 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+454.5K$11.00+$5.00M+3.3%14.4M afterDuplicate filing
Apr 4, 2025 (view filing)7:33 PM ETApr 31 dayOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+496.8K$20.13+$10.0MNew position443.8K after2 lotsDuplicate filing

IRON Disc Medicine, Inc.

Director8 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Feb 17, 2023 (view filing)4:43 PM ETFeb 152 daysOrbiMed Advisors LLC and 3 othersDirector, 10% OwnerPPurchase+108.7K$23.00+$2.50M+57.1%299.2K after3 lotsDuplicate filing
Dec 14, 2023 (view filing)5:44 PM ETDec 12-142 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−134.2K$58.88−$7.90M−15.6%727.8K after8 lotsDuplicate filing
Dec 15, 2023 (view filing)6:04 PM ETDec 141 dayOrbiMed Advisors LLC and 3 othersDirectorSSale−433.2K$56.75−$24.6M−65.9%224.4K after3 lotsDuplicate filing
Dec 20, 2023 (view filing)6:28 PM ETDec 182 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−1.72K$59.24−$102.1K−100.0%0 afterDuplicate filing
Jun 20, 2024 (view filing)5:19 PM ETJun 173 daysOrbiMed Advisors LLC and 3 othersDirectorPPurchase+83.3K$36.00+$3.00M+54.8%235.4K after3 lotsDuplicate filing
Mar 12, 2025 (view filing)9:34 PM ETMar 10-122 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−312.4K$54.31−$17.0M−61.7%194.2K after15 lotsDuplicate filing
Mar 21, 2025 (view filing)8:00 PM ETMar 19-212 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−52.4K$54.02−$2.83M−21.9%187.3K after9 lotsDuplicate filing
Mar 26, 2025 (view filing)7:00 PM ETMar 242 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−5.74K$54.11−$310.5K−3.0%186.5K after3 lotsDuplicate filing

22 more companies have matching trades: