| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Edris BadreddinChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $54.23 | −$1.08M | −10.5%169.7K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −49.0K | $54.24 | −$2.66M | −4.9%954.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 24, 2025 (view filing) | Feb 20 | 4 days | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.3K | $60.30 | −$1.77M | −2.8%1.03M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 24, 2025 (view filing) | Feb 20 | 4 days | Ashar BhaveshChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.02K | $61.19 | −$62.2K | −1.6%62.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 24, 2025 (view filing) | Feb 20 | 4 days | Lynch DanielDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −47.6K | $60.22 | −$2.87M | −36.5%82.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2025 (view filing) | Feb 14 | 5 days | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $59.92 | −$639.5K | −1.0%1.06M after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2025 (view filing) | Feb 14 | 5 days | Lynch DanielDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −400 | $60.00 | −$24.0K | −0.3%130.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Pichl DanielChief People Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.8K | $54.36 | −$1.62M | −37.0%50.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Lynch DanielDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −175.0K | $54.46 | −$9.53M | −57.2%130.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −48.0K | $53.30 | −$2.56M | −4.6%1.00M after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Hambleton JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.8K | $53.01 | −$730.2K | −77.1%4.09K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Edris BadreddinChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.0K | $53.13 | −$1.59M | −13.7%189.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 5, 2024 (view filing) | Dec 3 | 2 days | Edris BadreddinChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $41.96 | −$839.3K | −8.7%209.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 4, 2024 (view filing) | Dec 2 | 2 days | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −49.0K | $41.37 | −$2.03M | −4.6%1.01M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 4, 2024 (view filing) | Sep 3 | 1 day | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −49.0K | $40.57 | −$1.99M | −4.4%1.06M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 4, 2024 (view filing) | Sep 3 | 1 day | Edris BadreddinChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $40.65 | −$812.9K | −8.0%229.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2024 (view filing) | Jun 3 | 2 days | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −49.0K | $39.90 | −$1.96M | −4.2%1.11M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2024 (view filing) | Jun 3 | 2 days | Hambleton JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.65K | $40.03 | −$186.0K | −53.2%4.09K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2024 (view filing) | Jun 3 | 2 days | Edris BadreddinChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $40.07 | −$801.4K | −7.4%249.6K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 20, 2024 (view filing) | Feb 16 | 4 days | Pichl DanielChief People Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $50.10 | −$751.5K | −24.9%45.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 5, 2024 (view filing) | Feb 2-5 | 3 days | Ashar BhaveshChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.06K | $47.34 | −$381.4K | −12.2%58.2K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 5, 2024 (view filing) | Feb 2 | 3 days | Pichl DanielChief People Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −26.2K | $44.32 | −$1.16M | −36.7%45.2K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 21, 2023 (view filing) | Jul 19 | 2 days | Hambleton JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.42K | $29.31 | −$70.9K | −34.2%4.65K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 22, 2023 (view filing) | Jun 20 | 2 days | Hambleton JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.40K | $26.92 | −$64.6K | −25.4%7.07K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 20, 2023 (view filing) | Mar 16 | 4 days | Schwartz Jeffrey LawrenceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.75M | $28.50 | −$49.9M | −36.2%3.08M after | |
| Mar 16, 2023 (view filing) | Mar 15 | 1 day | Hambleton JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.11K | $31.50 | −$34.8K | −18.7%4.82K after | |
| Jan 27, 2023 (view filing) | Jan 26 | 1 day | Pichl DanielChief People Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −858 | $31.00 | −$26.6K | −2.4%35.2K after | |
| Sep 14, 2022 (view filing)4:24 PM ET | Sep 12 | 2 days | OrbiMed Advisors LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −153.9K | $31.96 | −$4.92M | −2.7%5.60M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 10, 2022 (view filing)4:22 PM ET | Aug 8-9 | 2 days | OrbiMed Advisors LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −274.6K | $38.11 | −$10.5M | −4.6%5.75M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 20, 2021 (view filing) | Oct 20 | Same day | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.1K | $58.67 | −$591.6K | −1.3%779.2K after | |
| Oct 19, 2021 (view filing) | Oct 18-19 | 1 day | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.4K | $58.65 | −$3.07M | −6.4%769.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 13, 2021 (view filing) | Oct 13 | Same day | Smith L. MaryChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $55.97 | −$559.7K | −5.6%167.5K after | |
| Aug 12, 2021 (view filing)8:38 PM ET | Aug 10 | 2 days | Schwartz Jeffrey Lawrence and 3 othersDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00M | $70.25 | −$70.3M | −17.1%4.83M after | |
| Jul 20, 2021 (view filing) | Jul 19-20 | 1 day | Islam SaqibChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −62.5K | $76.56 | −$4.79M | −7.1%821.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 14, 2021 (view filing) | Jul 13 | 1 day | Smith L. MaryChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $80.88 | −$808.8K | −5.6%167.5K after | |
| Jul 6, 2021 (view filing)4:42 PM ET | Jul 1 | 5 days | OrbiMed Advisors LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.0K | $85.01 | −$1.36M | −0.3%6.03M after | |
| Jul 1, 2021 (view filing) | Jul 1 | Same day | Edris BadreddinChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.0K | $85.35 | −$2.73M | −9.6%301.5K after | |
