| Sep 18, 20264:30 PM ET | Sep 16 – Sep 17, 2026 | Capper Joseph HDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +75K | $1.1839 | +$88.8K | 179.83K | +71.5% | SEC↗ |
| Sep 16, 20266:46 PM ET | Sep 14 – Sep 15, 2026 | Capper Joseph HDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +75K | $1.0459 | +$78.44K | 104.83K | +251.5% | SEC↗ |
| Aug 19, 20264:10 PM ET | Aug 17, 2026 | Getz Heather CChief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +12.5K | $0.6649 | +$8.31K | 532.5K | +2.4% | SEC↗ |
| Aug 17, 20264:32 PM ET | Aug 14, 2026 | Getz Heather CChief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +15K | $0.6978 | +$10.47K | 520K | +3.0% | SEC↗ |
| Nov 17, 20254:26 PM ET | Nov 17, 2025 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 others10% Owner, Other: See Remarks | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +3.6M | $1.11 | +$4M | 7.71M | +87.7% | SEC↗ |
| Oct 24, 2024 | Oct 24, 2024 | Cuca RobertoCOO and CFO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +64.44K | $2.25 | +$145K | 155.39K | +70.9% | SEC↗ |
| Oct 24, 2024 | Oct 24, 2024 | Talmo PaulChief Technology Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +22.22K | $2.25 | +$50K | 91.08K | +32.3% | SEC↗ |
| Oct 24, 2024 | Oct 24, 2024 | KOBLISH ANTONYChief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +88.89K | $2.25 | +$200K | 458.9K | +24.0% | SEC↗ |
| Oct 24, 2024 | Oct 24, 2024 | Firestone Gregory A.Chief Commercial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +6.67K | $2.25 | +$15K | 57.28K | +13.2% | SEC↗ |
| Jul 2, 20244:54 PM ET | Jun 28 – Jul 2, 2024 | ORBIMED ADVISORS LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −428.3K | $4.721 | −$2.02M | 2.41M | −15.1% | SEC↗ |
| Feb 16, 20244:10 PM ET | Apr 1, 2020 – Jul 14, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 others10% Owner, Other: See Remarks | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +326.06K | $9.3182 | +$3.04M | 3.61M | +9.9% | SEC↗ |
| Dec 7, 2023 | Dec 5, 2023 | Firestone Gregory A.Chief Business Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +2.6K | $5.65 | +$14.69K | 35.51K | +7.9% | SEC↗ |
| Nov 14, 2023 | Nov 14, 2023 | Cuca RobertoCOO and CFO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +10K | $4.49 | +$44.9K | 62.37K | +19.1% | SEC↗ |
| Nov 14, 2023 | Nov 14, 2023 | KOBLISH ANTONYChief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +11K | $4.54 | +$49.94K | 303.63K | +3.8% | SEC↗ |
| Apr 21, 20235:08 PM ET | Apr 19 – Apr 21, 2023 | ORBIMED ADVISORS LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −192K | $9.335 | −$1.79M | 2.84M | −6.3% | SEC↗ |
| Nov 4, 2022 | Nov 3, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +20.26K | $7.81 | +$158.25K | 124.81K | +19.4% | SEC↗ |
| Oct 11, 2022 | Oct 11, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +16K | $8.00 | +$128K | 123.55K | +14.9% | SEC↗ |
| Sep 26, 2022 | Sep 23, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +6.8K | $7.99 | +$54.36K | 122.55K | +5.9% | SEC↗ |
| Sep 19, 2022 | Sep 19, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +18K | $8.09 | +$145.62K | 122.25K | +17.3% | SEC↗ |
| Sep 16, 2022 | Sep 15 – Sep 16, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +6.53K | $8.0927 | +$52.85K | 121.25K | +5.7% | SEC↗ |
| Sep 15, 2022 | Aug 16, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +5.22K | $8.10 | +$42.29K | 120.22K | +4.5% | SEC↗ |
| Aug 19, 20224:07 PM ET | Aug 17, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +500K | $8.00 | +$4M | 4.11M | +13.9% | SEC↗ |
| Aug 16, 2022 | Aug 16, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +315K | $8.00 | +$2.52M | 120K | New position | SEC↗ |
| Aug 12, 2022AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. | Aug 1, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +4.98K | $7.96 | +$39.63K | 100.68K | +5.2% | SEC↗ |
| Aug 12, 2022 | Aug 10, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +11.98K | $8.52 | +$102.06K | 105K | +12.9% | SEC↗ |
| Jul 22, 2022 | Jul 22, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +5.2K | $8.02 | +$41.7K | 100.2K | +5.5% | SEC↗ |
| Jul 21, 2022 | Jul 21, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +10.33K | $8.034 | +$83.02K | 100K | +11.5% | SEC↗ |
| Jul 20, 2022 | Jul 20, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +5.1K | $8.08 | +$41.21K | 99.17K | +5.4% | SEC↗ |
| Jul 13, 20227:55 PM ET | Jul 11 – Jul 13, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $8.0233 | +$120.35K | 3.61M | +0.4% | SEC↗ |
| Jul 8, 20225:58 PM ET | Jul 6 – Jul 8, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $7.9633 | +$119.45K | 3.59M | +0.4% | SEC↗ |
| Jul 5, 20227:37 PM ET | Jun 30 – Jul 5, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $7.2867 | +$109.3K | 3.58M | +0.4% | SEC↗ |
| Jul 5, 2022 | Jul 1, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +200 | $7.00 | +$1.4K | 98.57K | +0.2% | SEC↗ |
| Jun 30, 2022 | Jun 29 – Jun 30, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +3.57K | $7.00 | +$24.97K | 98.37K | +3.8% | SEC↗ |
| Jun 29, 20226:13 PM ET | Jun 27 – Jun 28, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $7.1367 | +$107.05K | 3.56M | +0.4% | SEC↗ |
| Jun 24, 20227:06 PM ET | Jun 22 – Jun 24, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $6.84 | +$102.6K | 3.55M | +0.4% | SEC↗ |
| Jun 24, 2022 | Jun 22, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +2.4K | $6.99 | +$16.78K | 97.8K | +2.5% | SEC↗ |
| Jun 22, 2022 | Jun 10 – Jun 22, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +52.4K | $6.50 | +$340.6K | 97.4K | +116.4% | SEC↗ |
| Jun 21, 20226:43 PM ET | Jun 16 – Jun 21, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $6.1433 | +$92.15K | 3.53M | +0.4% | SEC↗ |
| Jun 15, 20226:11 PM ET | Jun 13 – Jun 15, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $5.8567 | +$87.85K | 3.52M | +0.4% | SEC↗ |
| Jun 10, 20226:04 PM ET | Jun 8 – Jun 10, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $5.9833 | +$89.75K | 3.5M | +0.4% | SEC↗ |
| Jun 10, 2022 | Jun 10, 2022 | Opaleye Management Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +27.5K | $5.60 | +$154K | 95K | +40.7% | SEC↗ |
| Jun 7, 20226:16 PM ET | Jun 3 – Jun 7, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $6.1267 | +$91.9K | 3.49M | +0.4% | SEC↗ |
| Jun 7, 2022 | Jun 7, 2022 | Cuca RobertoCOO and CFO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +15K | $5.50 | +$82.5K | 34.89K | +75.4% | SEC↗ |
| Jun 2, 20227:24 PM ET | May 31 – Jun 2, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $6.9933 | +$104.9K | 3.47M | +0.4% | SEC↗ |
| May 27, 20226:45 PM ET | May 25 – May 27, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $7.1133 | +$106.7K | 3.46M | +0.4% | SEC↗ |
| May 24, 20226:41 PM ET | May 20 – May 24, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $8.17 | +$122.55K | 3.44M | +0.4% | SEC↗ |
| May 19, 20227:02 PM ET | May 17 – May 19, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $8.9633 | +$134.45K | 3.43M | +0.4% | SEC↗ |
| May 16, 20226:22 PM ET | May 12 – May 16, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $8.4333 | +$126.5K | 3.41M | +0.4% | SEC↗ |
| May 11, 20226:19 PM ET | May 9 – May 11, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +15K | $9.1567 | +$137.35K | 3.4M | +0.4% | SEC↗ |
| May 9, 20225:17 PM ET | May 5 – May 6, 2022 | EW HEALTHCARE PARTNERS FUND 2, L.P. and 3 othersOther: See footnote 2 | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, par value $0.001 per share | +10K | $9.585 | +$95.85K | 3.38M | +0.3% | SEC↗ |
