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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Little House Capital LLC9,134$4.54M1.02%+173+1.9%Added
Sigma Investment Counselors Inc9,089$4.51M0.22%−528−5.5%Reduced
Ashford Capital Management Inc9,078$4.51M0.48%00.0%Unchanged
Lombard Odier Asset Management (Switzerland) SA9,072$4.51M0.14%−240−2.6%Reduced
Tema ETFs LLC9,060$4.50M0.15%−580−6.0%Reduced
Traynor Capital Management, Inc.9,049$4.49M0.21%−2,757−23.4%Reduced
Univest Financial Corp9,049$4.49M0.22%+1,986+28.1%Added
Canal Capital Management, LLC9,045$4.49M0.55%+9,045New
Aware Super Pty Ltd as trustee of Aware Super9,038$4.49M0.06%+9,038New
EP Wealth Advisors, LLC9,027$4.48M0.02%+390+4.5%Added
Sivik Global Healthcare LLC10,000$4.46M3.39%00.0%Unchanged
Empirical Finance, LLC8,986$4.46M0.19%+292+3.4%Added
Machina Capital S.A.S.8,966$4.45M0.71%−688−7.1%Reduced
Perigon Wealth Management, LLC8,834$4.39M0.07%+2,380+36.9%Added
E. Ohman J:or Asset Management AB8,823$4.38M0.10%00.0%Unchanged
Brown Brothers Harriman & Co8,785$4.36M0.02%+2,947+50.5%Added
Sterling Capital Management LLC8,648$4.30M0.07%−4,690−35.2%Reduced
Sepio Capital, LP8,623$4.28M0.22%+329+4.0%Added
MASTERINVEST Kapitalanlage GmbH8,519$4.23M0.36%+226+2.7%Added
Bensler, LLC8,506$4.23M0.37%+250+3.0%Added
Notis-McConarty Edward8,423$4.18M1.81%+538+6.8%Added
RDA Financial Network8,419$4.18M0.91%+1,236+17.2%Added
Cumberland Partners Ltd8,368$4.16M0.27%−1,008−10.8%Reduced
Quantitative Investment Management, LLC8,342$4.14M0.45%+8,342New
Dempze Nancy E8,282$4.11M1.97%+472+6.0%Added
Y-Intercept (Hong Kong) Ltd8,281$4.11M0.08%−27,548−76.9%Reduced
Mission Wealth Management, LP8,170$4.06M0.05%+4,075+99.5%Added
Northwestern Mutual Investment Management Company, LLC8,137$4.04M0.05%+10+0.1%Added
Howard Capital Management Inc.8,113$4.03M0.05%+4,143+104.4%Added
Linden Thomas Advisory Services, LLC8,103$4.03M0.32%−20−0.2%Reduced
Envestnet Portfolio Solutions, Inc.8,064$4.01M0.02%−633−7.3%Reduced
Brighton Jones LLC8,048$4.00M0.07%+1,292+19.1%Added
Commerce Bank8,033$3.99M0.02%+498+6.6%Added
Cresset Asset Management, LLC7,926$3.94M0.01%+66+0.8%Added
Gabelli Funds LLC7,891$3.92M0.03%−29−0.4%Reduced
Vise Technologies, Inc.7,882$3.91M0.04%+2,623+49.9%Added
Baldwin Brothers Inc7,824$3.89M0.25%00.0%Unchanged
J.P. Marvel Investment Advisors, LLC7,810$3.88M0.45%−45−0.6%Reduced
Vestmark Advisory Solutions, Inc.7,762$3.86M0.04%+805+11.6%Added
BLI - Banque de Luxembourg Investments7,700$3.86M0.14%+2,200+40.0%Added
MUFG Securities Americas Inc.7,645$3.80M0.19%+617+8.8%Added
Brown Advisory Inc7,562$3.76M0.01%−91−1.2%Reduced
North Dakota State Investment Board7,547$3.75M0.15%+97+1.3%Added
EagleClaw Capital Managment, LLC7,535$3.74M0.50%+150+2.0%Added
Hedeker Wealth, LLC7,515$3.73M0.71%−111−1.5%Reduced
Graphene Investments SAS7,500$3.73M2.17%+900+13.6%Added
Aigen Investment Management, LP7,452$3.70M1.01%+3,214+75.8%Added
Camden Capital, LLC7,449$3.70M0.18%+1,520+25.6%Added
Summit Trail Advisors, LLC7,429$3.69M0.05%+182+2.5%Added
Johnson Investment Counsel Inc7,360$3.66M0.03%+17+0.2%Added
Legacy Capital Wealth Management, LLC7,333$3.64M1.69%+1,484+25.4%Added
First National Bank of Mount Dora, Trust Investment Services7,194$3.57M0.72%−17−0.2%Reduced
Crestwood Advisors Group LLC7,184$3.57M0.05%−572−7.4%Reduced
Summit Global Investments7,182$3.57M0.19%+3,286+84.3%Added
Mirova7,071$3.51M0.13%−3,312−31.9%Reduced
Catalyst Funds Management Pty Ltd7,001$3.48M0.20%+6,036+625.5%Added
Scotia Capital Inc.6,981$3.47M0.01%+2,120+43.6%Added
GAMMA Investing LLC6,918$3.44M0.13%+326+4.9%Added
Commerzbank Aktiengesellschaft6,857$3.41M0.07%−424−5.8%Reduced
North Star Asset Management Inc6,833$3.39M0.13%−26−0.4%Reduced
Associated Banc-Corp6,791$3.37M0.08%−24−0.4%Reduced
South Dakota Investment Council6,760$3.36M0.06%+360+5.6%Added
Glenview Trust Co6,751$3.35M0.05%−244−3.5%Reduced
Northwest & Ethical Investments L.P.6,664$3.31M0.08%−5,278−44.2%Reduced
Kentucky Retirement Systems Insurance Trust Fund6,649$3.30M0.20%−119−1.8%Reduced
Central Trust Co6,641$3.30M0.06%−322−4.6%Reduced
Vision Capital Management, Inc.6,630$3.29M0.38%−69−1.0%Reduced
Securian Asset Management, Inc6,767$3.29M0.12%−132−1.9%Reduced
Bokf, NA6,560$3.26M0.04%+625+10.5%Added
Sumitomo Life Insurance Co6,558$3.26M0.05%−1,197−15.4%Reduced
Lighthouse Financial LLC6,515$3.24M1.68%+238+3.8%Added
RSM US Wealth Management LLC6,474$3.22M0.04%+308+5.0%Added
Canada Post Corp Registered Pension Plan6,474$3.22M0.11%00.0%Unchanged
Meeder Advisory Services, Inc.6,415$3.19M0.12%+218+3.5%Added
Thompson Siegel & Walmsley LLC6,408$3.18M0.06%−29−0.5%Reduced
Kinneret Advisory, LLC6,397$3.18M0.26%00.0%Unchanged
Aster Capital Management (DIFC) Ltd6,302$3.13M0.67%+6,302New
B&L Asset Management LLC6,249$3.10M1.07%−430−6.4%Reduced
Montchanin Asset Management, LLC6,232$3.10M3.16%−700−10.1%Reduced
Boothbay Fund Management, LLC6,174$3.07M0.06%+4,854+367.7%Added
Coldstream Capital Management Inc6,151$3.06M0.04%−386−5.9%Reduced
Griffin Asset Management, Inc.6,142$3.05M0.32%−33−0.5%Reduced
Financial Advisors Network, Inc.6,125$3.04M0.37%+298+5.1%Added
CSM Advisors, LLC6,133$3.04M0.06%−4,705−43.4%Reduced
Atomi Financial Group, Inc.6,108$3.03M0.08%−558−8.4%Reduced
Wahed Invest LLC6,050$3.01M0.31%−365−5.7%Reduced
Plato Investment Management Ltd6,083$3.00M0.17%+148+2.5%Added
Bamco Inc6,000$2.98M0.00%−1,500−20.0%Reduced
Cohen Klingenstein LLC6,000$2.98M0.09%00.0%Unchanged
Phoenix Holdings Ltd.5,993$2.98M0.02%+1,160+24.0%Added
Hall Laurie J Trustee5,990$2.98M0.93%+30+0.5%Added
Principal Securities, Inc.5,982$2.97M0.04%−596−9.1%Reduced
Westview Management dba Westview Investment Advisors5,981$2.97M1.45%+127+2.2%Added
Freedom Day Solutions, LLC5,934$2.95M0.65%+19+0.3%Added
Integrated Wealth Concepts LLC5,917$2.94M0.02%+1,249+26.8%Added
Harbour Capital Advisors, LLC6,051$2.94M0.53%+57+1.0%Added
Sand Hill Global Advisors, LLC5,885$2.92M0.09%−484−7.6%Reduced
Mediolanum International Funds Ltd5,776$2.89M0.02%+71+1.2%Added
Wimmer Associates 1, LLC5,796$2.88M1.30%+63+1.1%Added
Livforsakringsbolaget Skandia, Omsesidigt5,780$2.87M0.10%+3,900+207.4%Added