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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Signature Estate & Investment Advisors LLC478$237.8K0.00%+478New
VisionPoint Advisory Group, LLC479$237.9K0.04%−285−37.3%Reduced
Legacy Wealth Advisors, LLC481$238.9K0.10%+481New
CVA Family Office, LLC482$239.4K0.02%+10+2.1%Added
Boston Trust Walden Corp485$240.9K0.00%00.0%Unchanged
Loudon Investment Management, LLC485$240.9K0.12%00.0%Unchanged
Guerra Pan Advisors, LLC485$240.9K0.13%00.0%Unchanged
Johnson Financial Group, LLC486$241.4K0.01%+486New
55 North Private Wealth, LLC487$241.9K0.05%+18+3.8%Added
Quadrant Private Wealth Management, LLC489$242.9K0.05%+489New
Arthur M. Cohen & Associates, LLC490$243.4K0.04%00.0%Unchanged
Trinity Legacy Partners, LLC503$244.5K0.05%+8+1.6%Added
Ewa, LLC492$244.6K0.04%+12+2.5%Added
Salem Investment Counselors Inc494$245.4K0.01%00.0%Unchanged
Banque Transatlantique SA507$245.8K0.01%+42+9.0%Added
Smithfield Trust Co503$247.0K0.01%00.0%Unchanged
Focus Financial Network, Inc.498$247.4K0.01%+5+1.0%Added
D.B. Root & Company, LLC499$247.9K0.05%−155−23.7%Reduced
Fielder Capital Group LLC499$247.9K0.05%−77−13.4%Reduced
Community Bank, N.A.500$248.4K0.03%−380−43.2%Reduced
Bramshill Investments, LLC500$248.4K0.02%00.0%Unchanged
Arlington Financial Advisors, LLC500$248.4K0.03%00.0%Unchanged
McHugh Group, LLC500$248.4K0.13%00.0%Unchanged
Royal Capital Wealth Management, LLC500$248.4K0.14%+500New
Brookstone Capital Management500$248.4K0.00%+3+0.6%Added
Heartwood Wealth Advisors LLC503$249.9K0.02%−8−1.6%Reduced
SLT Holdings LLC503$249.9K0.16%+20+4.1%Added
US Asset Management LLC504$250.4K0.19%00.0%Unchanged
Five Oceans Advisors506$251.3K0.08%−2−0.4%Reduced
BLB&B Advisors, LLC506$251.3K0.01%−14−2.7%Reduced
Axiom Investment Management LLC507$251.8K0.17%−126−19.9%Reduced
Tillman Hartley LLC508$252.3K0.06%00.0%Unchanged
Legacy Advisors, LLC508$252.3K0.02%+508New
Capula Management Ltd509$252.8K0.00%+262+106.1%Added
Central Bank & Trust Co510$253.3K0.04%+510New
Caerus Investment Advisors, LLC510$253.3K0.09%+510New
Interchange Capital Partners, LLC511$253.8K0.05%−408−44.4%Reduced
Mengis Capital Management, Inc.511$253.8K0.04%+11+2.2%Added
Csenge Advisory Group511$253.9K0.01%−90−15.0%Reduced
Equitable Trust Co512$254.3K0.01%−50−8.9%Reduced
Great Lakes Advisors, LLC513$254.8K0.00%+35+7.3%Added
Sound Income Strategies, LLC515$255.8K0.01%−14−2.6%Reduced
Vilga Financial Planning LLC515$255.8K0.19%00.0%Unchanged
Balentine LLC515$255.8K0.01%+515New
Fortitude Advisory Group L.L.C.517$256.8K0.10%+517New
First Foundation Advisors519$257.8K0.01%−1−0.2%Reduced
Holderness Investments Co519$257.8K0.04%+30+6.1%Added
Empower Advisory Group, LLC521$258.8K0.00%−25−4.6%Reduced
Strive Financial Group ,LLC525$260.8K0.11%+395+303.8%Added
Planning Alternatives Ltd527$261.8K0.03%−48−8.3%Reduced
Kathmere Capital Management, LLC529$262.8K0.01%+40+8.2%Added
Vanguard Capital Wealth Advisors530$263.3K0.18%00.0%Unchanged
Hanson & Doremus Investment Management534$265.0K0.03%−20−3.6%Reduced
Morris Financial Concepts, Inc.536$266.2K0.08%+6+1.1%Added
Washington Trust Co537$266.7K0.01%00.0%Unchanged
Coastline Trust Co537$266.7K0.02%00.0%Unchanged
M. Kulyk & Associates, LLC537$266.7K0.04%+52+10.7%Added
United Advisor Group, LLC539$267.7K0.03%−6−1.1%Reduced
Brian Low Financial Group, LLC542$269.2K0.16%+6+1.1%Added
McAdam, LLC543$269.5K0.01%+543New
Mainsail Asset Management, LLC556$270.0K0.11%+100+21.9%Added
OneAscent Family Office, LLC544$270.2K0.14%+544New
SHP Wealth Management544$270.3K0.02%+20+3.8%Added
Range Advisory, LLC546$271.1K0.03%+546New
Klingman & Associates, LLC547$271.7K0.01%+18+3.4%Added
180 Wealth Advisors, LLC548$272.1K0.03%−27−4.7%Reduced
Private Trust Co NA548$272.2K0.02%+15+2.8%Added
KPP Advisory Services LLC549$272.7K0.03%−42−7.1%Reduced
QTR Family Wealth, LLC550$273.2K0.10%+550New
Green Alpha Advisors, LLC552$274.2K0.18%+6+1.1%Added
TBH Global Asset Management, LLC554$275.2K0.05%−15−2.6%Reduced
Nvest Financial, LLC554$275.2K0.09%00.0%Unchanged
Cary Street Partner Investment Advisory LLC555$275.7K0.06%−13−2.3%Reduced
Prestige Wealth Management Group LLC556$276.2K0.05%−291−34.4%Reduced
Armis Advisers, LLC522$276.4K0.03%+27+5.5%Added
Drucker Wealth 3.0, LLC556$276.6K0.04%+42+8.2%Added
Cladis Investment Advisory, LLC559$277.7K0.13%+17+3.1%Added
Keating Financial Advisory Services, Inc.559$277.7K0.04%+143+34.4%Added
Beacon Financial Advisory LLC562$279.2K0.05%−7−1.2%Reduced
Riverwater Partners LLC563$279.7K0.08%+38+7.2%Added
Crewe Advisors LLC563$279.7K0.02%+63+12.6%Added
Fi3 FINANCIAL ADVISORS, LLC6,625$280.5K0.08%+6,625New
Monetary Management Group Inc565$280.7K0.06%00.0%Unchanged
Walkner Condon Financial Advisors LLC573$284.6K0.03%−5−0.9%Reduced
Whittier Trust Co of Nevada Inc546$285.1K0.01%−23−4.0%Reduced
Berman McAleer LLC574$285.2K0.03%+17+3.1%Added
Meyer Handelman Co575$285.6K0.01%00.0%Unchanged
Bartlett & Co. Wealth Management LLC575$285.6K0.00%+5+0.9%Added
Joel Isaacson & Co., LLC575$285.6K0.01%+69+13.6%Added
Foster Group, Inc.575$285.6K0.01%+81+16.4%Added
Peregrine Asset Advisers, Inc.583$289.6K0.06%+1+0.2%Added
Jupiter Asset Management Ltd583$289.6K0.00%+583New
Cim, LLC584$290.1K0.04%−45−7.2%Reduced
Kelly Lawrence W & Associates Inc585$290.6K0.06%00.0%Unchanged
Fairfield, Bush & Co.586$291.1K0.14%−25−4.1%Reduced
Icapital Wealth LLC591$293.6K0.16%00.0%Unchanged
Copper Harbor Investment Advisors, LLC592$294.1K0.06%+592New
Impact Partnership Wealth, LLC592$294.1K0.03%+131+28.4%Added
Winthrop Advisory Group LLC594$294.9K0.02%+105+21.5%Added
Parcion Private Wealth LLC596$296.1K0.02%+596New