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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Citadel Advisors LLC510,430$253.5M0.15%+171,132+50.4%Added
Life Cycle Investment Partners Ltd514,179$255.4M1.19%+73,770+16.8%Added
SG Americas Securities, LLC523,720$260.1M0.15%+466,738+819.1%Added
Edgewood Management LLC531,003$263.8M2.72%−374,126−41.3%Reduced
National Pension Service539,530$268.0M0.17%+7,461+1.4%Added
Pictet Asset Management Holding SA539,255$268.3M0.26%+201,686+59.7%Added
Marshall Wace, LLP543,897$270.2M0.23%+226,839+71.5%Added
Vanguard Global Advisers, LLC547,463$271.9M0.13%−8,270−1.5%Reduced
Manufacturers Life Insurance Company, The554,085$275.2M0.22%+842+0.2%Added
Raymond James Financial Inc556,876$276.6M0.08%+112,380+25.3%Added
Neuberger Berman Group LLC559,445$277.9M0.19%+7,923+1.4%Added
Bellevue Group AG578,634$287.4M6.05%−103,274−15.1%Reduced
American Century Companies Inc580,901$288.6M0.13%−232,384−28.6%Reduced
Sumitomo Mitsui Trust Holdings, Inc.611,907$304.0M0.17%−2,541−0.4%Reduced
AQR Capital Management LLC616,170$305.0M0.11%+445,139+260.3%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.647,193$321.5M0.18%+49,696+8.3%Added
HSBC Holdings PLC676,247$335.8M0.16%+20,804+3.2%Added
Citigroup Inc706,968$351.2M0.16%+24,161+3.5%Added
UBS Group AG712,259$353.8M0.06%+81,641+12.9%Added
Swiss National Bank717,440$356.4M0.19%−27,160−3.6%Reduced
Barclays PLC733,274$364.2M0.11%+70,011+10.6%Added
Arrowstreet Capital, Limited Partnership738,378$366.8M0.16%+99,428+15.6%Added
Wells Fargo & Company749,528$372.3M0.06%+4,533+0.6%Added
Assenagon Asset Management S.A.759,564$377.3M0.49%+222,316+41.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.897,893$446.0M0.45%+49,846+5.9%Added
Royal Bank of Canada980,259$486.9M0.08%−131,612−11.8%Reduced
Nuveen, LLC1,081,685$537.3M0.13%−2,810−0.3%Reduced
WCM Investment Management, LLC1,152,094$575.6M1.04%+30,753+2.7%Added
Dimensional Fund Advisors LP1,168,956$580.7M0.11%+179,614+18.2%Added
Jupiter Topco LLC1,259,997$625.8M0.26%+1,259,997New
Vanguard Fiduciary Trust Co1,425,390$708.0M0.16%−40,334−2.8%Reduced
FMR LLC1,457,158$723.8M0.03%−563,107−27.9%Reduced
Amundi1,546,509$768.2M0.18%+74,013+5.0%Added
Deutsche Bank AG1,579,110$784.4M0.23%+41,374+2.7%Added
Bank of New York Mellon Corp1,672,623$830.8M0.14%+86,196+5.4%Added
Price T Rowe Associates Inc1,728,421$858.6M0.09%−31,701−1.8%Reduced
Legal & General Group Plc1,870,015$928.9M0.19%−85,749−4.4%Reduced
Charles Schwab Investment Management Inc2,041,282$1.01B0.13%+120,411+6.3%Added
Victory Capital Management Inc2,173,152$1.08B0.61%+284,631+15.1%Added
Clearbridge Investments, LLC2,342,915$1.16B0.96%−358,060−13.3%Reduced
Goldman Sachs Group Inc2,481,761$1.23B0.13%+63,886+2.6%Added
Northern Trust Corp2,486,478$1.24B0.14%−77,786−3.0%Reduced
Ameriprise Financial Inc2,604,822$1.29B0.26%−28,659−1.1%Reduced
Alliancebernstein L.P.3,019,315$1.35B0.48%−891,471−22.8%Reduced
Norges Bank2,971,681$1.48B0.15%+2,971,681New
Jennison Associates LLC2,998,530$1.49B0.89%+258,471+9.4%Added
Bank of America Corp3,039,178$1.51B0.10%+160,995+5.6%Added
UBS Asset Management Americas Inc3,086,683$1.53B0.28%+29,287+1.0%Added
Morgan Stanley3,242,139$1.61B0.09%+53,258+1.7%Added
Wellington Management Group LLP3,247,658$1.61B0.28%+35,069+1.1%Added
Franklin Resources Inc3,347,253$1.66B0.36%+2,796,121+507.3%Added
Loomis Sayles & Co L P3,920,953$1.95B2.45%−82,868−2.1%Reduced
Capital International Investors4,695,144$2.33B0.48%−430,933−8.4%Reduced
Vanguard Portfolio Management LLC4,878,987$2.42B0.11%−266,622−5.2%Reduced
Geode Capital Management, LLC6,017,848$2.98B0.16%−121,773−2.0%Reduced
JPMorgan Chase & Co6,517,600$3.26B0.19%−515,556−7.3%Reduced
Invesco Ltd.8,043,052$4.00B0.32%+150,441+1.9%Added
State Street Corp11,871,459$5.90B0.17%+141,320+1.2%Added
Vanguard Capital Management LLC16,580,713$8.24B0.18%+67,903+0.4%Added
Capital Research Global Investors19,490,637$9.68B1.35%−1,635,327−7.7%Reduced
BlackRock, Inc.24,109,373$12.0B0.18%+139,856+0.6%Added
Capital World Investors26,115,014$13.0B1.53%+746,890+2.9%Added
Coppell Advisory Solutions LLC436––+436New
Smith Group Asset Management, LLC0$00.00%−55,746−100.0%Sold out
Gradient Investments LLC0$00.00%−41,736−100.0%Sold out
Caxton Associates LLP0$00.00%−36,026−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−22,403−100.0%Sold out
XTX Topco Ltd0$00.00%−15,632−100.0%Sold out
Trexquant Investment LP0$00.00%−15,171−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−15,075−100.0%Sold out
Superstring Capital Management LP0$00.00%−11,010−100.0%Sold out
Group One Trading, L.P.0$00.00%−9,357−100.0%Sold out
Emerald Investment Advisers, LLC0$00.00%−8,012−100.0%Sold out
Twin Tree Management, LP0$00.00%−7,769−100.0%Sold out
Virtu Financial LLC0$00.00%−7,634−100.0%Sold out
Freemont Management S.A.0$00.00%−6,500−100.0%Sold out
Havemeyer Place LP0$00.00%−5,655−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−5,580−100.0%Sold out
Fiduciary Alliance LLC0$00.00%−5,583−100.0%Sold out
IMC-Chicago, LLC0$00.00%−4,533−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−3,998−100.0%Sold out
Mattson Financial Services, LLC0$00.00%−3,861−100.0%Sold out
Diadema Partners LP0$00.00%−3,840−100.0%Sold out
GLR Partners, LLC0$00.00%−3,538−100.0%Sold out
Arrowpoint Investment Partners (Singapore) Pte. Ltd.0$00.00%−3,412−100.0%Sold out
SWS Partners0$00.00%−2,573−100.0%Sold out
Oxford Asset Management LLP0$00.00%−2,499−100.0%Sold out
PeakShares LLC0$00.00%−2,458−100.0%Sold out
Centiva Capital, LP0$00.00%−2,147−100.0%Sold out
Brown Financial Advisors0$00.00%−2,141−100.0%Sold out
Oak Ridge Investments LLC0$00.00%−2,009−100.0%Sold out
Farringdon Capital, Ltd.0$00.00%−1,831−100.0%Sold out
Polymer Capital Management (US) LLC0$00.00%−1,669−100.0%Sold out
Magnetar Financial LLC0$00.00%−1,672−100.0%Sold out
Stevens Capital Management LP0$00.00%−1,588−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−1,570−100.0%Sold out
Lecap Asset Management Ltd0$00.00%−1,507−100.0%Sold out
Evoke Wealth, LLC0$00.00%−1,485−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,401−100.0%Sold out
BankChampaign, National Association0$00.00%−1,374−100.0%Sold out