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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Varma Mutual Pension Insurance Co40,826$20.3M0.11%−2,800−6.4%Reduced
Public Sector Pension Investment Board41,334$20.5M0.05%+157+0.4%Added
Wealthfront Advisers LLC41,608$20.7M0.04%−4,787−10.3%Reduced
O'Shaughnessy Asset Management, LLC42,063$20.9M0.10%−19,804−32.0%Reduced
Acadian Asset Management LLC42,122$20.9M0.02%+16,254+62.8%Added
Federated Hermes, Inc.42,663$21.2M0.03%−29,159−40.6%Reduced
Martingale Asset Management L P42,729$21.2M0.50%−2,021−4.5%Reduced
JustInvest LLC43,151$21.4M0.18%+1,528+3.7%Added
New York Life Investment Management LLC43,218$21.5M0.15%+5,149+13.5%Added
Wealth Enhancement Advisory Services, LLC45,889$21.5M0.04%+5,221+12.8%Added
Zurich Insurance Group Ltd43,589$21.7M0.15%−1,029−2.3%Reduced
W.G. Shaheen & Associates DBA Whitney & Co44,714$22.2M1.62%+597+1.4%Added
Lido Advisors, LLC45,347$22.5M0.08%+1,836+4.2%Added
Ossiam45,879$22.8M0.30%+6,522+16.6%Added
Xponance, Inc.45,980$22.8M0.14%−24,734−35.0%Reduced
Pathstone Holdings, LLC45,952$22.9M0.07%+1,690+3.8%Added
C WorldWide Group Holding A/S46,057$22.9M0.55%00.0%Unchanged
Quadrature Capital Ltd46,945$23.3M0.20%+46,945New
Adams Diversified Equity Fund, Inc.47,300$23.5M0.72%+47,300New
Amalgamated Bank47,716$23.7M0.16%−5,553−10.4%Reduced
China Universal Asset Management Co., Ltd.48,265$24.0M1.43%+4,363+9.9%Added
Davidson Investment Advisors48,710$24.2M0.99%−2,512−4.9%Reduced
USS Investment Management Ltd48,893$24.3M0.10%+1,765+3.7%Added
HighTower Advisors, LLC49,020$24.3M0.02%−16,664−25.4%Reduced
Advisor Group Holdings, Inc.49,586$24.6M0.03%+5,614+12.8%Added
Empowered Funds, LLC50,197$24.9M0.13%+8,460+20.3%Added
Commonwealth Equity Services, LLC50,813$25.2M0.03%−4,159−7.6%Reduced
Pinebridge Investments LLC50,819$25.2M0.21%−4,281−7.8%Reduced
Citizens Financial Group Inc50,988$25.3M0.31%+1,164+2.3%Added
Hallmark Capital Management Inc51,329$25.5M1.47%+1,190+2.4%Added
Cullinan Associates Inc51,762$25.7M1.94%00.0%Unchanged
Retirement Systems of Alabama53,319$26.5M0.08%−619−1.1%Reduced
Beacon Investment Advisory Services, Inc.53,380$26.5M0.99%−2,724−4.9%Reduced
PensionDanmark Pensionsforsikringsaktieselskab54,094$26.9M0.22%+4,890+9.9%Added
Reynders McVeigh Capital Management, LLC54,499$27.1M1.20%−165−0.3%Reduced
Edgemoor Investment Advisors, Inc.55,020$27.3M1.86%−395−0.7%Reduced
Zacks Investment Management55,052$27.3M0.19%−30−0.1%Reduced
Hemenway Trust Co LLC55,995$27.8M1.94%+4,496+8.7%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys56,059$27.8M0.14%−3,108−5.3%Reduced
Atwood & Palmer Inc56,357$28.0M1.49%+604+1.1%Added
Nisa Investment Advisors, LLC56,455$28.0M0.09%−1,728−3.0%Reduced
Moody Lynn & Lieberson, LLC56,624$28.1M1.48%−1,016−1.8%Reduced
Hardman Johnston Global Advisors LLC57,683$28.7M1.01%−674−1.2%Reduced
IFM Investors Pty Ltd57,713$28.7M0.19%+6,643+13.0%Added
MetLife Investment Management58,072$28.8M0.13%−12,732−18.0%Reduced
Foster Dykema Cabot & Partners, LLC58,233$28.9M1.68%+441+0.8%Added
Natixis59,095$29.4M0.14%+10,903+22.6%Added
Tredje AP-fonden59,459$29.5M0.13%−14,340−19.4%Reduced
Trillium Asset Management, LLC60,105$29.9M0.92%−39,657−39.8%Reduced
Assetmark, Inc61,055$30.3M0.05%+1,101+1.8%Added
Rakuten Investment Management, Inc.61,183$30.6M0.09%+8,493+16.1%Added
GF Fund Management Co. Ltd.62,678$31.1M0.37%−1,913−3.0%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd63,330$31.5M0.22%−492−0.8%Reduced
Apollon Wealth Management, LLC63,910$31.7M0.39%+25,315+65.6%Added
Rafferty Asset Management, LLC65,798$32.7M0.07%+11,226+20.6%Added
STRS Ohio66,679$33.1M0.12%−7,484−10.1%Reduced
Gateway Investment Advisers LLC67,289$33.4M0.33%+168+0.3%Added
State of Michigan Retirement System67,823$33.7M0.15%−1,300−1.9%Reduced
The PNC Financial Services Group, Inc.69,358$34.5M0.02%−2,584−3.6%Reduced
Arizona State Retirement System70,580$35.1M0.18%+1,065+1.5%Added
Capital Fund Management S.A.71,088$35.3M0.25%−51,846−42.2%Reduced
Daiwa Securities Group Inc.71,534$35.5M0.08%+3,995+5.9%Added
Czech National Bank72,243$35.9M0.20%+3,067+4.4%Added
Pacer Advisors, Inc.72,465$36.0M0.09%−16,398−18.5%Reduced
Mn Services Vermogensbeheer B.V.74,100$36.8M0.28%+74,100New
Calamos Advisors LLC75,388$37.4M0.14%−2,498−3.2%Reduced
Nissay Asset Management Corp75,743$37.6M0.16%+4,280+6.0%Added
Erste Asset Management GmbH76,558$38.2M0.30%−15,400−16.7%Reduced
Cetera Investment Advisers78,107$38.8M0.04%+5,474+7.5%Added
Lansforsakringar Fondforvaltning AB (publ)79,627$39.6M0.18%−4,219−5.0%Reduced
Vontobel Holding Ltd.81,525$40.5M0.14%−1,855−2.2%Reduced
Fifth Third Bancorp81,898$40.7M0.07%−6,601−7.5%Reduced
State of New Jersey Common Pension Fund D82,245$40.9M0.14%−4,465−5.1%Reduced
Eurizon Capital SGR S.p.A.82,582$41.0M0.11%+1,073+1.3%Added
Resona Asset Management Co.,Ltd.84,092$41.8M0.20%−6,220−6.9%Reduced
Abn Amro Investment Solutions84,631$42.0M0.36%+16,415+24.1%Added
Toronto Dominion Bank85,391$42.4M0.07%+6,919+8.8%Added
Janney Montgomery Scott LLC85,735$42.6M0.08%+1,411+1.7%Added
Susquehanna Portfolio Strategies, LLC90,928$45.2M0.72%+61,739+211.5%Added
Swiss Life Asset Management Ltd91,614$45.5M0.19%+9,040+10.9%Added
State of Tennessee, Treasury Department93,032$46.2M0.14%+11,364+13.9%Added
Lazard Asset Management LLC93,287$46.3M0.07%−119,844−56.2%Reduced
PFA Pension, Forsikringsaktieselskab93,959$46.7M0.12%−41,037−30.4%Reduced
Virginia Retirement Systems Et Al94,060$46.7M0.28%00.0%Unchanged
Kovitz Investment Group Partners, LLC95,246$47.3M1.05%+4,361+4.8%Added
Toroso Investments, LLC95,685$47.5M0.12%+3,604+3.9%Added
Capital International Ltd97,334$48.3M1.58%+1,460+1.5%Added
Raiffeisen Bank International AG97,170$48.6M0.57%−4,265−4.2%Reduced
Public Employees Retirement System of Ohio98,068$48.7M0.14%−4,917−4.8%Reduced
Country Trust Bank100,360$49.9M0.87%−4,715−4.5%Reduced
Mackenzie Financial Corp102,928$51.1M0.05%+6,219+6.4%Added
Intermede Investment Partners Ltd101,619$51.5M2.17%−4,751−4.5%Reduced
CI Private Wealth, LLC103,755$51.5M0.07%+17,263+20.0%Added
CIBC Asset Management Inc104,292$51.8M0.11%−2,601−2.4%Reduced
KLP Kapitalforvaltning AS104,741$52.0M0.17%+9,360+9.8%Added
Truist Financial Corp106,967$53.1M0.06%−7,482−6.5%Reduced
Storebrand Asset Management AS107,628$53.5M0.13%+5,061+4.9%Added
Banco Santander, S.A.108,075$53.7M0.33%+8,687+8.7%Added
DnB Asset Management AS108,106$53.7M0.15%+795+0.7%Added
Treasurer of the State of North Carolina108,303$53.8M0.14%−360−0.3%Reduced