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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
South Dakota Investment Council6,760$3.36M0.06%+360+5.6%Added
Associated Banc-Corp6,791$3.37M0.08%−24−0.4%Reduced
North Star Asset Management Inc6,833$3.39M0.13%−26−0.4%Reduced
Commerzbank Aktiengesellschaft6,857$3.41M0.07%−424−5.8%Reduced
GAMMA Investing LLC6,918$3.44M0.13%+326+4.9%Added
Scotia Capital Inc.6,981$3.47M0.01%+2,120+43.6%Added
Catalyst Funds Management Pty Ltd7,001$3.48M0.20%+6,036+625.5%Added
Mirova7,071$3.51M0.13%−3,312−31.9%Reduced
Summit Global Investments7,182$3.57M0.19%+3,286+84.3%Added
Crestwood Advisors Group LLC7,184$3.57M0.05%−572−7.4%Reduced
First National Bank of Mount Dora, Trust Investment Services7,194$3.57M0.72%−17−0.2%Reduced
Legacy Capital Wealth Management, LLC7,333$3.64M1.69%+1,484+25.4%Added
Johnson Investment Counsel Inc7,360$3.66M0.03%+17+0.2%Added
Summit Trail Advisors, LLC7,429$3.69M0.05%+182+2.5%Added
Camden Capital, LLC7,449$3.70M0.18%+1,520+25.6%Added
Aigen Investment Management, LP7,452$3.70M1.01%+3,214+75.8%Added
Graphene Investments SAS7,500$3.73M2.17%+900+13.6%Added
Hedeker Wealth, LLC7,515$3.73M0.71%−111−1.5%Reduced
EagleClaw Capital Managment, LLC7,535$3.74M0.50%+150+2.0%Added
North Dakota State Investment Board7,547$3.75M0.15%+97+1.3%Added
Brown Advisory Inc7,562$3.76M0.01%−91−1.2%Reduced
MUFG Securities Americas Inc.7,645$3.80M0.19%+617+8.8%Added
BLI - Banque de Luxembourg Investments7,700$3.86M0.14%+2,200+40.0%Added
Vestmark Advisory Solutions, Inc.7,762$3.86M0.04%+805+11.6%Added
J.P. Marvel Investment Advisors, LLC7,810$3.88M0.45%−45−0.6%Reduced
Baldwin Brothers Inc7,824$3.89M0.25%00.0%Unchanged
Vise Technologies, Inc.7,882$3.91M0.04%+2,623+49.9%Added
Gabelli Funds LLC7,891$3.92M0.03%−29−0.4%Reduced
Cresset Asset Management, LLC7,926$3.94M0.01%+66+0.8%Added
Commerce Bank8,033$3.99M0.02%+498+6.6%Added
Brighton Jones LLC8,048$4.00M0.07%+1,292+19.1%Added
Envestnet Portfolio Solutions, Inc.8,064$4.01M0.02%−633−7.3%Reduced
Linden Thomas Advisory Services, LLC8,103$4.03M0.32%−20−0.2%Reduced
Howard Capital Management Inc.8,113$4.03M0.05%+4,143+104.4%Added
Northwestern Mutual Investment Management Company, LLC8,137$4.04M0.05%+10+0.1%Added
Mission Wealth Management, LP8,170$4.06M0.05%+4,075+99.5%Added
Y-Intercept (Hong Kong) Ltd8,281$4.11M0.08%−27,548−76.9%Reduced
Dempze Nancy E8,282$4.11M1.97%+472+6.0%Added
Quantitative Investment Management, LLC8,342$4.14M0.45%+8,342New
Cumberland Partners Ltd8,368$4.16M0.27%−1,008−10.8%Reduced
RDA Financial Network8,419$4.18M0.91%+1,236+17.2%Added
Notis-McConarty Edward8,423$4.18M1.81%+538+6.8%Added
Bensler, LLC8,506$4.23M0.37%+250+3.0%Added
MASTERINVEST Kapitalanlage GmbH8,519$4.23M0.36%+226+2.7%Added
Sepio Capital, LP8,623$4.28M0.22%+329+4.0%Added
Sterling Capital Management LLC8,648$4.30M0.07%−4,690−35.2%Reduced
Brown Brothers Harriman & Co8,785$4.36M0.02%+2,947+50.5%Added
E. Ohman J:or Asset Management AB8,823$4.38M0.10%00.0%Unchanged
Perigon Wealth Management, LLC8,834$4.39M0.07%+2,380+36.9%Added
Machina Capital S.A.S.8,966$4.45M0.71%−688−7.1%Reduced
Empirical Finance, LLC8,986$4.46M0.19%+292+3.4%Added
Sivik Global Healthcare LLC10,000$4.46M3.39%00.0%Unchanged
EP Wealth Advisors, LLC9,027$4.48M0.02%+390+4.5%Added
Aware Super Pty Ltd as trustee of Aware Super9,038$4.49M0.06%+9,038New
Canal Capital Management, LLC9,045$4.49M0.55%+9,045New
Univest Financial Corp9,049$4.49M0.22%+1,986+28.1%Added
Traynor Capital Management, Inc.9,049$4.49M0.21%−2,757−23.4%Reduced
Tema ETFs LLC9,060$4.50M0.15%−580−6.0%Reduced
Lombard Odier Asset Management (Switzerland) SA9,072$4.51M0.14%−240−2.6%Reduced
Ashford Capital Management Inc9,078$4.51M0.48%00.0%Unchanged
Sigma Investment Counselors Inc9,089$4.51M0.22%−528−5.5%Reduced
Little House Capital LLC9,134$4.54M1.02%+173+1.9%Added
Ofi Invest Asset Management10,449$4.54M0.05%−58,784−84.9%Reduced
Peloton Wealth Strategists9,280$4.61M1.70%+140+1.5%Added
Elefante Mark B9,285$4.61M1.99%+1,144+14.1%Added
Mark Sheptoff Financial Planning, LLC9,295$4.62M2.45%−251−2.6%Reduced
Privium Fund Management B.V.9,400$4.67M0.86%−1,955−17.2%Reduced
Caption Management, LLC9,400$4.67M0.16%+9,200+4,600.0%Added
Jain Global LLC9,529$4.73M0.06%+4,852+103.7%Added
Northwestern Mutual Wealth Management Co9,613$4.78M0.00%+757+8.5%Added
Parsons Capital Management Inc9,779$4.86M0.22%+138+1.4%Added
Tokio Marine Asset Management Co Ltd9,895$4.92M0.15%+471+5.0%Added
Keybank National Association9,934$4.93M0.02%−468−4.5%Reduced
LMR Partners LLP9,962$4.95M0.04%−9,891−49.8%Reduced
Fayez Sarofim & Co10,000$4.97M0.01%00.0%Unchanged
Banque Cantonale Vaudoise10,020$4.98M0.19%+1,093+12.2%Added
Level Four Advisory Services, LLC10,034$4.98M0.14%+510+5.4%Added
Nwam LLC10,129$5.03M0.25%+3,797+60.0%Added
Concurrent Investment Advisors, LLC10,145$5.04M0.04%+661+7.0%Added
Oddo BHF Asset Management SAS10,151$5.04M0.23%00.0%Unchanged
Park Avenue Securities LLC10,198$5.07M0.03%−1,713−14.4%Reduced
Miracle Mile Advisors, LLC10,324$5.13M0.06%+806+8.5%Added
GAM Holding AG10,376$5.15M0.39%+4,796+85.9%Added
Bessemer Group Inc10,408$5.17M0.01%+1,843+21.5%Added
Simplify Asset Management Inc.10,456$5.19M0.07%+2,520+31.8%Added
Morse Asset Management, Inc10,526$5.23M0.87%−39−0.4%Reduced
Kestra Private Wealth Services, LLC10,539$5.24M0.06%+864+8.9%Added
Generali Investments CEE, investicni spolecnost, a.s.10,599$5.26M0.25%00.0%Unchanged
Northwest Bancshares, Inc.10,706$5.32M0.96%+288+2.8%Added
Joseph Group Capital Management10,756$5.34M1.12%+242+2.3%Added
Bridgewater Associates, LP10,865$5.40M0.02%−2,492−18.7%Reduced
New Age Alpha Advisors, LLC10,927$5.43M0.23%−491−4.3%Reduced
Metis Global Partners, LLC10,929$5.43M0.12%−738−6.3%Reduced
Benjamin Edwards Inc11,025$5.48M0.05%−92−0.8%Reduced
PKO Investment Management Joint-Stock Co11,050$5.49M0.40%+50+0.5%Added
HB Wealth Management, LLC11,065$5.50M0.03%+778+7.6%Added
Jones Hill Capital LP11,123$5.53M1.17%−97,480−89.8%Reduced
First Horizon Corp11,201$5.56M0.21%−3,334−22.9%Reduced
Jane Street Group, LLC11,231$5.58M0.00%−111,715−90.9%Reduced
NewEdge Wealth, LLC11,305$5.62M0.06%+1,517+15.5%Added