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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Montis Financial, LLC1,810$808.2K0.17%+87+5.0%Added
Guidance Capital, Inc1,907$809.3K0.18%+110+6.1%Added
Pensionmark Financial Group, LLC1,820$812.8K0.01%−152−7.7%Reduced
Savvy Advisors, Inc.1,821$813.1K0.02%+61+3.5%Added
TD Private Client Wealth LLC1,824$814.5K0.02%−19−1.0%Reduced
Alesco Advisors LLC1,825$814.9K0.02%+1,825New
TCG Advisory Services, LLC1,829$816.7K0.02%+423+30.1%Added
Farringdon Capital, Ltd.1,831$817.6K0.18%+1,831New
Calamos Wealth Management LLC1,834$819.0K0.03%+1,186+183.0%Added
Perpetual Ltd1,837$820.3K0.01%+201+12.3%Added
Baker Ellis Asset Management LLC1,852$827.0K0.10%−100−5.1%Reduced
Gryphon Financial Partners LLC1,856$828.8K0.09%−39−2.1%Reduced
One Wealth Capital Management, LLC1,936$832.8K0.36%+670+52.9%Added
Premier Path Wealth Partners, LLC1,870$835.1K0.11%+62+3.4%Added
Twin Capital Management Inc1,879$839.0K0.11%−40−2.1%Reduced
Livforsakringsbolaget Skandia, Omsesidigt1,880$839.3K0.03%00.0%Unchanged
Badgley Phelps Wealth Managers, LLC1,881$839.9K0.02%−6−0.3%Reduced
Quadcap Wealth Management, LLC1,891$844.4K0.10%+101+5.6%Added
Blue Chip Partners, Inc.1,895$846.2K0.06%+204+12.1%Added
Legacy Capital Wealth Partners, LLC1,901$848.9K0.17%+174+10.1%Added
Spire Wealth Management1,905$850.5K0.03%−50−2.6%Reduced
Change Path, LLC1,924$859.1K0.02%−166−7.9%Reduced
Annis Gardner Whiting Capital Advisors, LLC1,925$859.6K0.14%−39−2.0%Reduced
CX Institutional1,940$866.0K0.03%+2+0.1%Added
Woodward Diversified Capital, LLC1,974$870.9K0.40%+1,974New
Breakwater Capital Group1,962$876.1K0.12%−13−0.7%Reduced
Milestone Asset Management, LLC1,975$881.9K0.16%−1,164−37.1%Reduced
Howland Capital Management LLC1,975$881.9K0.03%+96+5.1%Added
Fortis Capital Advisors, LLC1,980$884.1K0.12%−124−5.9%Reduced
Formidable Asset Management, LLC1,970$885.2K0.14%+59+3.1%Added
Spears Abacus Advisors LLC1,983$885.5K0.02%+23+1.2%Added
Principal Street Partners, LLC1,987$887.3K0.14%+2+0.1%Added
Schmidt P J Investment Management Inc1,997$891.7K0.15%−56−2.7%Reduced
Mystic Asset Management, Inc.2,000$893.1K0.21%00.0%Unchanged
Bay Rivers Group2,000$893.1K0.37%+2,000New
Advisory Alpha, LLC2,001$893.5K0.02%−13−0.6%Reduced
Oak Ridge Investments LLC2,009$897.1K0.06%−931−31.7%Reduced
Mitchell & Pahl Private Wealth, LLC2,009$897.1K0.36%−40−2.0%Reduced
Argent Trust Co2,017$900.7K0.03%−126−5.9%Reduced
Allegheny Financial Group LTD2,018$901.1K0.12%+15+0.7%Added
Great Lakes Retirement, Inc.2,025$904.2K0.09%+116+6.1%Added
Mount Yale Investment Advisors, LLC2,029$906.0K0.02%−107−5.0%Reduced
Rehmann Capital Advisory Group2,039$910.5K0.05%+102+5.3%Added
Westco Advisory Services Inc2,049$915.0K0.59%−84−3.9%Reduced
HM Payson & Co2,052$916.3K0.01%−51−2.4%Reduced
GraniteShares Advisors LLC2,058$919.0K0.66%−506−19.7%Reduced
Ipswich Investment Management Co., Inc.2,063$921.2K0.22%+20+1.0%Added
Wealth Science Advisors LLC2,036$923.0K0.52%00.0%Unchanged
Duncker Streett & Co Inc2,091$933.7K0.18%−20−0.9%Reduced
Pflug Koory, LLC2,092$934.2K0.43%−11−0.5%Reduced
Evercore Wealth Management, LLC2,098$936.8K0.01%−8−0.4%Reduced
Generali Investments Towarzystwo Funduszy Inwestycyjnych2,100$937.7K0.48%00.0%Unchanged
Nikko Asset Management Americas, Inc.2,115$944.3K0.01%−4,199−66.5%Reduced
Fifth Third Wealth Advisors LLC2,129$950.7K0.03%+415+24.2%Added
PFG Investments, LLC2,134$952.9K0.04%−9−0.4%Reduced
Presilium Private Wealth, LLC2,137$954.3K0.17%+10+0.5%Added
Brown Financial Advisors2,141$956.0K0.36%−227−9.6%Reduced
Journey Strategic Wealth LLC2,143$956.9K0.02%+702+48.7%Added
Centiva Capital, LP2,147$958.7K0.04%+2,147New
Fidelis Capital Partners, LLC2,155$962.3K0.07%00.0%Unchanged
ZWJ Investment Counsel Inc2,156$962.7K0.03%−831−27.8%Reduced
Impact Capital Partners LLC2,163$965.9K0.29%−63−2.8%Reduced
Waterfront Wealth Inc.2,169$968.5K0.18%+88+4.2%Added
Legacy Capital Group California, Inc.2,180$973.5K0.37%−322−12.9%Reduced
PCM Encore, LLC2,195$980.1K0.20%+128+6.2%Added
Kornitzer Capital Management Inc2,210$986.9K0.02%−35−1.6%Reduced
MAI Capital Management2,218$990.4K0.01%−346−13.5%Reduced
Headinvest, LLC2,262$1.01M0.21%−45−2.0%Reduced
Alps Advisors Inc2,268$1.01M0.00%−230−9.2%Reduced
VestGen Advisors, LLC2,272$1.02M0.03%+245+12.1%Added
National Asset Management, Inc.2,317$1.03M0.07%−1,138−32.9%Reduced
Davis Investment Partners, LLC2,316$1.03M0.37%−240−9.4%Reduced
Dorsey & Whitney Trust CO LLC2,320$1.04M0.06%+47+2.1%Added
Prime Capital Investment Advisors, LLC2,334$1.04M0.01%−75−3.1%Reduced
Prospera Financial Services Inc2,360$1.05M0.02%+75+3.3%Added
OpenArc Corporate Advisory, LLC2,395$1.07M0.02%+550+29.8%Added
Rare Wolf Capital LLC2,425$1.08M0.70%+410+20.3%Added
Fred Alger Management, LLC2,433$1.09M0.00%00.0%Unchanged
Cigna Investments Inc2,434$1.09M0.17%−48−1.9%Reduced
Everhart Financial Group, Inc.2,455$1.10M0.09%+204+9.1%Added
PeakShares LLC2,458$1.10M1.01%+214+9.5%Added
Koa Wealth Management, LLC2,468$1.10M0.80%−115−4.5%Reduced
Souders Financial Advisors2,497$1.12M0.13%+491+24.5%Added
Oxford Asset Management LLP2,499$1.12M0.45%+977+64.2%Added
Strid Group, LLC2,500$1.12M0.14%00.0%Unchanged
Nippon Life Global Investors Americas, Inc.2,500$1.12M0.05%+250+11.1%Added
Westport Asset Management Inc2,500$1.12M0.49%00.0%Unchanged
Transcend Wealth Collective, LLC2,503$1.12M0.09%+490+24.3%Added
Westbourne Investments, Inc.2,506$1.12M0.53%00.0%Unchanged
Moody National Bank Trust Division2,517$1.12M0.11%+41+1.7%Added
Westpac Banking Corp2,529$1.13M0.08%−76−2.9%Reduced
Journey Retirement Planning & Investment Management LLC2,555$1.14M1.00%−7,337−74.2%Reduced
Ashton Thomas Private Wealth, LLC2,556$1.14M0.03%+53+2.1%Added
Philip James Wealth Mangement, LLC2,570$1.15M0.13%−58−2.2%Reduced
SWS Partners2,573$1.15M0.28%+42+1.7%Added
Regal Investment Advisors LLC2,583$1.15M0.07%+43+1.7%Added
Malaga Cove Capital, LLC2,591$1.16M0.42%+119+4.8%Added
Qtron Investments LLC2,602$1.16M0.16%00.0%Unchanged
AlphaCore Capital LLC2,626$1.17M0.03%−2,254−46.2%Reduced
Grove Bank & Trust2,647$1.18M0.13%+563+27.0%Added