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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Asset One Wealth Management LLC689$300.8K0.03%+689New
Park Place Capital Corp675$301.4K0.06%+50+8.0%Added
Mesirow Financial Investment Management, Inc.678$302.8K0.00%+185+37.5%Added
Cidel Asset Management Inc679$303.2K0.02%+147+27.6%Added
Seven Mile Advisory681$304.1K0.22%−97−12.5%Reduced
TRUE Private Wealth Advisors681$304.4K0.03%+5+0.7%Added
Continuum Advisory, LLC685$305.9K0.03%−947−58.0%Reduced
Alpha Zero LLC685$305.9K0.15%−23−3.2%Reduced
Graham Capital Management, L.P.686$306.3K0.01%−507−42.5%Reduced
Venture Visionary Partners LLC688$307.2K0.01%−466−40.4%Reduced
Navigation Group, LLC696$310.8K0.07%+696New
Onefund, LLC699$312.6K0.20%−35−4.8%Reduced
Stock Yards Bank & Trust Co701$313.0K0.01%+10+1.4%Added
Cambient Family Office, LLC705$314.8K0.04%+123+21.1%Added
FourThought Financial Partners, LLC710$317.0K0.03%−38−5.1%Reduced
TRB Wealth Management, LLC711$317.5K0.05%+711New
Alpine Woods Capital Investors, LLC716$319.7K0.08%−686−48.9%Reduced
Wedgewood Investors Inc720$321.5K0.37%00.0%Unchanged
Strategic Blueprint, LLC721$322.0K0.02%+121+20.2%Added
Financial Symmetry Inc760$324.9K0.12%+5+0.7%Added
Castleark Management LLC730$326.0K0.01%00.0%Unchanged
Diversified Trust Co731$326.4K0.01%+70+10.6%Added
Sustainable Insight Capital Management, LLC731$326.4K0.11%+200+37.7%Added
Nicholas Hoffman & Company, LLC.732$326.9K0.01%00.0%Unchanged
Ignite Planners, LLC732$326.9K0.05%+65+9.7%Added
Parkside Financial Bank & Trust735$328.2K0.03%−267−26.6%Reduced
LaFleur & Godfrey LLC744$332.2K0.04%+262+54.4%Added
Essex Financial Services, Inc.748$334.0K0.02%−118−13.6%Reduced
ISAM Funds (UK) Ltd750$334.9K0.17%−2,471−76.7%Reduced
Baker Chad R750$334.9K0.06%00.0%Unchanged
Northstar Asset Management LLC750$334.9K0.08%00.0%Unchanged
Cura Wealth Advisors, LLC760$339.3K0.15%00.0%Unchanged
VisionPoint Advisory Group, LLC764$341.2K0.06%−38−4.7%Reduced
Income Insurance Ltd764$341.2K0.23%00.0%Unchanged
ICW Investment Advisors LLC765$341.7K0.12%+101+15.2%Added
denkapparat Operations GmbH766$342.1K0.14%00.0%Unchanged
Guardian Asset Advisors, LLC770$343.8K0.20%−115−13.0%Reduced
Trust Point Inc.772$344.7K0.03%+272+54.4%Added
AlphaGrep UK Ltd774$345.6K0.10%+14+1.8%Added
Nautilus Advisors LLC777$347.0K0.24%+67+9.4%Added
Daymark Wealth Partners, LLC777$347.0K0.01%+80+11.5%Added
Cercano Management LLC780$348.3K0.02%00.0%Unchanged
Basecamp Wealth Advisors LLC788$351.9K0.07%−1−0.1%Reduced
Newman Dignan & Sheerar, Inc.792$353.7K0.07%+13+1.7%Added
Arlington Capital Management, Inc.800$357.2K0.20%00.0%Unchanged
Custom Index Systems, LLC801$357.7K0.16%+251+45.6%Added
Legato Capital Management LLC808$360.8K0.03%−333−29.2%Reduced
Strategic Investment Advisors809$361.7K0.02%−702−46.5%Reduced
Eagle Wealth Advisors LLC812$362.6K0.33%+96+13.4%Added
Montag A & Associates Inc817$364.8K0.02%+20+2.5%Added
Relyea Zuckerberg Hanson LLC827$369.3K0.04%+251+43.6%Added
Canandaigua National Corp827$369.3K0.03%+827New
Meridian Wealth Management, LLC828$369.7K0.01%+18+2.2%Added
Gateway Wealth Partners, LLC832$371.5K0.01%+832New
Defiance ETFs, LLC840$375.1K0.01%+840New
Douglass Winthrop Advisors, LLC841$375.5K0.01%00.0%Unchanged
YHB Investment Advisors, Inc.841$375.5K0.03%00.0%Unchanged
Wrapmanager Inc843$376.4K0.13%−313−27.1%Reduced
Prestige Wealth Management Group LLC847$378.2K0.07%−11−1.3%Reduced
HBK Sorce Advisory LLC882$379.0K0.01%+47+5.6%Added
Delta Financial Advisors LLC863$385.4K0.10%−9−1.0%Reduced
Westfield Capital Management Co LP864$385.8K0.00%−268−23.7%Reduced
FSM Wealth Advisors, LLC864$385.9K0.05%+41+5.0%Added
Prescott Group Capital Management, L.L.C.869$388.0K0.04%00.0%Unchanged
George Kaiser Family Foundation869$388.0K0.04%00.0%Unchanged
Chesley Taft & Associates LLC869$388.0K0.02%+87+11.1%Added
Alvarez & Marsal Private Wealth Partners, LLC869$388.0K0.05%+191+28.2%Added
Fragasso Group Inc.895$388.7K0.02%−353−28.3%Reduced
Pinnacle Wealth Management Advisory Group, LLC874$390.3K0.03%+94+12.1%Added
Bluedoor Private Wealth, LLC876$391.2K0.18%+59+7.2%Added
Richardson Financial Services Inc.877$391.6K0.25%−75−7.9%Reduced
Community Bank, N.A.880$392.9K0.05%−2,247−71.9%Reduced
Forza Wealth Management, LLC881$393.4K0.14%00.0%Unchanged
Oasis Advisors, LLC885$395.2K0.08%+885New
SmartHarvest Portfolios, LLC886$395.6K0.17%−256−22.4%Reduced
Harbour Investments, Inc.888$396.7K0.01%+395+80.1%Added
Independence Bank of Kentucky891$397.9K0.05%+15+1.7%Added
Wealthspire Advisors, LLC895$399.7K0.00%−930−51.0%Reduced
Buckingham Strategic Partners897$400.8K0.00%+897New
Jump Financial, LLC899$401.4K0.01%−2,863−76.1%Reduced
RMB Capital Management, LLC899$401.5K0.01%−92−9.3%Reduced
Great Valley Advisor Group, Inc.900$401.8K0.01%−7−0.8%Reduced
Freestone Capital Holdings, LLC900$401.9K0.01%+51+6.0%Added
Oxford Financial Group Ltd900$401.9K0.02%+900New
SK Wealth Management, LLC927$402.6K0.11%00.0%Unchanged
National Wealth Management Group, LLC902$402.8K0.15%−627−41.0%Reduced
Fulton Bank, N.A.905$404.1K0.01%−22−2.4%Reduced
E Fund Management (Hong Kong) Co., Ltd.907$405.0K0.18%+47+5.5%Added
Severin Investments, LLC908$405.5K0.35%+908New
Granite Bay Wealth Management, LLC910$406.6K0.09%+8+0.9%Added
Abundance Wealth Counselors913$407.7K0.06%+250+37.7%Added
AA Financial Advisors, LLC919$410.4K0.06%+73+8.6%Added
Everpar Advisors LLC919$410.4K0.14%+121+15.2%Added
Oversea-Chinese Banking CORP Ltd922$411.6K0.01%+922New
Ausdal Financial Partners, Inc.926$413.4K0.02%−12−1.3%Reduced
RiverFront Investment Group, LLC929$414.8K0.01%+30+3.3%Added
Diversify Advisory Services, LLC981$415.2K0.06%−6,146−86.2%Reduced
Montecito Bank & Trust930$415.3K0.07%−297−24.2%Reduced
Cabot Wealth Management Inc930$415.3K0.05%00.0%Unchanged
Collaborative Fund Advisors, LLC930$415.3K0.26%+930New