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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
LRI Investments, LLC385$171.9K0.02%+11+2.9%Added
Anchor Investment Management, LLC391$174.6K0.01%−104−21.0%Reduced
Manchester Capital Management LLC396$176.8K0.03%−9−2.2%Reduced
Private Wealth Asset Management, LLC401$179.1K0.02%−1−0.2%Reduced
Mitsubishi UFJ Morgan Stanley Securities Co., Ltd.413$184.4K0.45%−41−9.0%Reduced
Keating Financial Advisory Services, Inc.416$185.8K0.03%+49+13.4%Added
Ronald Blue Trust, Inc.425$189.6K0.00%−912−68.2%Reduced
International Assets Investment Management, LLC426$190.5K0.01%+16+3.9%Added
Rothschild Investment LLC437$195.1K0.01%+50+12.9%Added
Corient IA LLC440$196.5K0.18%−60−12.0%Reduced
Tradition Wealth Management, LLC449$200.5K0.01%+449New
Cornerstone Planning, LLC450$200.9K0.05%00.0%Unchanged
PFW Advisors LLC450$200.9K0.06%00.0%Unchanged
OneAscent Financial Services LLC453$202.3K0.01%+453New
Mainsail Asset Management, LLC456$203.6K0.09%+2+0.4%Added
Ledyard National Bank457$204.1K0.02%+4+0.9%Added
First American Trust, FSB458$204.8K0.01%−2,019−81.5%Reduced
Adirondack Trust Co459$204.9K0.07%−24−5.0%Reduced
Liberty Wealth Management LLC460$205.4K0.03%+1+0.2%Added
Impact Partnership Wealth, LLC461$205.9K0.03%−19−4.0%Reduced
Fortress Private Ledger, LLC463$206.7K0.06%+463New
Banque Transatlantique SA465$207.8K0.00%−74−13.7%Reduced
Xxi Wealth, LLC466$208.1K0.12%+466New
Marble Wealth, LLC467$208.3K0.04%−398−46.0%Reduced
55 North Private Wealth, LLC469$209.4K0.05%+469New
Sage Capital Management, LLC472$210.8K0.10%00.0%Unchanged
CVA Family Office, LLC472$210.8K0.02%+79+20.1%Added
KC Investment Advisors, LLC475$212.1K0.05%−77−13.9%Reduced
Pathway Wealth Management LLC475$212.1K0.20%00.0%Unchanged
Aviso Financial Inc.476$212.6K0.01%−2,576−84.4%Reduced
Heritage Investors Management Corp476$213.0K0.01%−10−2.1%Reduced
Great Lakes Advisors, LLC478$213.4K0.00%+7+1.5%Added
Ewa, LLC480$214.5K0.05%+480New
Sageworth Trust Co481$214.8K0.01%+481New
SLT Holdings LLC483$215.7K0.15%+483New
Epoch Investment Partners, Inc.485$216.6K0.00%00.0%Unchanged
Boston Trust Walden Corp485$216.6K0.00%00.0%Unchanged
Loudon Investment Management, LLC485$216.6K0.12%00.0%Unchanged
Guerra Pan Advisors, LLC485$216.6K0.13%+7+1.5%Added
M. Kulyk & Associates, LLC485$216.6K0.04%+485New
Paragon Private Wealth Management, LLC486$217.0K0.07%+36+8.0%Added
Clark Capital Management Group, Inc.487$217.5K0.00%−43−8.1%Reduced
Putney Financial Group LLC488$217.9K0.22%−7−1.4%Reduced
Winthrop Advisory Group LLC489$218.3K0.02%+489New
Holderness Investments Co489$218.4K0.04%+489New
Kathmere Capital Management, LLC489$218.4K0.01%+489New
Arthur M. Cohen & Associates, LLC490$219.2K0.04%−300−38.0%Reduced
Trinity Legacy Partners, LLC495$219.9K0.05%+15+3.1%Added
Focus Financial Network, Inc.493$220.1K0.01%−31−5.9%Reduced
Salem Investment Counselors Inc494$220.6K0.01%00.0%Unchanged
Onyx Bridge Wealth Group LLC494$220.6K0.02%+3+0.6%Added
Foster Group, Inc.494$220.6K0.01%+494New
HMS Capital Management, LLC497$221.9K0.09%00.0%Unchanged
Brookstone Capital Management497$222.0K0.00%−38−7.1%Reduced
Capital Asset Advisory Services LLC507$222.7K0.01%−58−10.3%Reduced
Parsonex Advisory Services, Inc.499$222.8K0.22%−532−51.6%Reduced
Altfest L J & Co Inc500$223.3K0.02%−1,324−72.6%Reduced
Crewe Advisors LLC500$223.3K0.02%−4−0.8%Reduced
Mengis Capital Management, Inc.500$223.3K0.04%00.0%Unchanged
Arlington Financial Advisors, LLC500$223.3K0.03%00.0%Unchanged
McHugh Group, LLC500$223.3K0.13%00.0%Unchanged
Bramshill Investments, LLC500$223.3K0.02%+500New
GM Advisory Group, Inc.502$224.2K0.01%−25−4.7%Reduced
Armis Advisers, LLC495$224.2K0.02%+495New
US Asset Management LLC504$225.1K0.19%+1+0.2%Added
Miller Capital Partners, Inc.505$225.5K0.11%00.0%Unchanged
Joel Isaacson & Co., LLC506$225.9K0.01%+14+2.8%Added
Smithfield Trust Co503$226.0K0.01%00.0%Unchanged
Ethos Financial Group, LLC507$226.4K0.02%−4−0.8%Reduced
Tillman Hartley LLC508$226.8K0.06%−32−5.9%Reduced
Five Oceans Advisors508$226.8K0.08%+1+0.2%Added
Beaumont Financial Advisors, LLC510$227.7K0.02%+24+4.9%Added
Heartwood Wealth Advisors LLC511$228.2K0.02%00.0%Unchanged
Voleon Capital Management LP513$229.1K0.00%+513New
CoreCap Advisors, LLC514$229.5K0.01%−6−1.2%Reduced
Drucker Wealth 3.0, LLC514$229.6K0.04%+20+4.0%Added
Vilga Financial Planning LLC515$230.0K0.21%00.0%Unchanged
New World Advisors LLC515$230.0K0.04%+515New
Pursuit Wealth Strategies, LLC517$230.9K0.32%−17−3.2%Reduced
Victory Financial Group, LLC517$230.9K0.03%+1+0.2%Added
Virtue Capital Management, LLC521$230.9K0.04%−8−1.5%Reduced
BKD Wealth Advisors, LLC518$231.3K0.00%+16+3.2%Added
First Foundation Advisors520$232.2K0.01%+5+1.0%Added
Inscription Capital, LLC520$232.2K0.02%+47+9.9%Added
BLB&B Advisors, LLC520$232.2K0.01%−8−1.5%Reduced
Pictet & Cie (Europe) SA522$233.1K0.00%+40+8.3%Added
EntryPoint Capital, LLC523$233.5K0.07%−543−50.9%Reduced
SHP Wealth Management524$234.0K0.02%+38+7.8%Added
Riverwater Partners LLC525$234.4K0.08%+525New
Patton Fund Management, Inc.526$234.9K0.04%+526New
Signature Wealth Management Group527$235.3K0.09%−3,797−87.8%Reduced
Klingman & Associates, LLC529$236.2K0.01%+64+13.8%Added
Sound Income Strategies, LLC529$236.6K0.01%+9+1.7%Added
Vanguard Capital Wealth Advisors530$236.7K0.22%00.0%Unchanged
Morris Financial Concepts, Inc.530$236.7K0.08%+23+4.5%Added
New Republic Capital, LLC532$237.7K0.08%−293−35.5%Reduced
Private Trust Co NA533$238.0K0.02%−7−1.3%Reduced
Brian Low Financial Group, LLC536$239.3K0.16%+13+2.5%Added
Washington Trust Co537$239.8K0.01%−197−26.8%Reduced
Coastline Trust Co537$239.8K0.02%−60−10.1%Reduced