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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
TSFG, LLC107$48.0K0.01%+107New
Lodestone Wealth Management LLC108$48.2K0.02%00.0%Unchanged
MidFirst Bank110$49.1K0.00%−21−16.0%Reduced
Atlas Capital Advisors LLC110$49.1K0.01%00.0%Unchanged
GoalVest Advisory LLC110$49.1K0.01%+10+10.0%Added
Cornerstone Planning Group LLC116$49.2K0.01%−8−6.5%Reduced
Brown, Lisle/Cummings, Inc.115$51.4K0.01%+33+40.2%Added
MTM Investment Management, LLC117$52.2K0.02%00.0%Unchanged
Capital Analysts, LLC119$53.0K0.00%+3+2.6%Added
Salomon & Ludwin, LLC121$53.1K0.00%00.0%Unchanged
Kilter Group LLC120$53.6K0.02%+2+1.7%Added
Gables Capital Management Inc.121$54.0K0.02%00.0%Unchanged
Smallwood Wealth Investment Management, LLC121$54.0K0.03%00.0%Unchanged
JPL Wealth Management, LLC122$54.6K0.01%+122New
Core Alternative Capital123$54.9K0.02%00.0%Unchanged
Financial Avengers, Inc.125$55.8K0.03%00.0%Unchanged
Atlantic Edge Private Wealth Management, LLC125$55.8K0.01%00.0%Unchanged
Antipodes Partners Ltd127$56.7K0.00%00.0%Unchanged
Bell Investment Advisors, Inc129$57.6K0.01%−3−2.3%Reduced
Strive Financial Group ,LLC130$58.0K0.03%+17+15.0%Added
Triumph Capital Management131$58.5K0.01%+15+12.9%Added
Raleigh Capital Management Inc.137$61.2K0.02%+17+14.2%Added
Itau Unibanco Holding S.A.142$63.4K0.00%+4+2.9%Added
Purpose Unlimited Inc.143$63.8K0.00%−692−82.9%Reduced
Migdal Insurance & Financial Holdings Ltd.145$64.7K0.00%+145New
St Germain D J Co Inc148$66.1K0.00%−13−8.1%Reduced
Chelsea Counsel Co150$67.0K0.03%00.0%Unchanged
PFS Partners, LLC158$70.6K0.03%00.0%Unchanged
Boreal Capital Management LLC159$71.0K0.06%00.0%Unchanged
Truvestments Capital LLC160$71.4K0.01%−4−2.4%Reduced
City State Bank160$71.4K0.02%00.0%Unchanged
Golden State Equity Partners161$71.9K0.01%+161New
Atlantic Trust, LLC161$71.9K0.01%00.0%Unchanged
Cassaday & Co Wealth Management LLC162$72.3K0.00%+162New
Steigerwald, Gordon & Koch Inc.167$74.6K0.01%00.0%Unchanged
GHP Investment Advisors, Inc.168$75.2K0.00%+43+34.4%Added
Plante Moran Financial Advisors, LLC169$75.5K0.00%−5−2.9%Reduced
Farmers & Merchants Investments Inc170$75.9K0.00%00.0%Unchanged
1620 Investment Advisors, Inc.175$78.2K0.05%−3−1.7%Reduced
Westside Investment Management, Inc.179$78.6K0.01%00.0%Unchanged
Financial Network Wealth Advisors LLC178$79.5K0.08%+79+79.8%Added
Glen Eagle Advisors, LLC180$80.4K0.01%+176+4,400.0%Added
Rosenberg Matthew Hamilton184$82.2K0.02%00.0%Unchanged
REAP Financial Group, LLC184$82.2K0.02%+2+1.1%Added
Cornerstone Financial Management LLC184$82.2K0.08%+2+1.1%Added
GW&K Investment Management, LLC186$83.0K0.00%+35+23.2%Added
Ameriflex Group, Inc.187$83.5K0.04%+21+12.7%Added
Edmond de Rothschild Holding S.A.191$85.3K0.00%00.0%Unchanged
Valley National Advisers Inc194$86.0K0.01%+9+4.9%Added
MCF Advisors LLC197$88.0K0.00%−57−22.4%Reduced
Moisand Fitzgerald Tamayo, LLC200$89.3K0.01%00.0%Unchanged
Caption Management, LLC200$89.3K0.00%+200New
RWM Asset Management, LLC200$89.3K0.01%+200New
Vestor Capital, LLC202$90.0K0.01%+56+38.4%Added
Crews Bank & Trust212$94.7K0.01%00.0%Unchanged
Whipplewood Advisors, LLC217$96.9K0.05%+210+3,000.0%Added
Golden State Wealth Management, LLC227$101.4K0.01%−23−9.2%Reduced
Rossby Financial, LCC228$102.0K0.02%−28−10.9%Reduced
Cache Advisors, LLC231$103.2K0.01%+231New
Sankala Group LLC233$103.7K0.08%00.0%Unchanged
Asset Dedication, LLC237$105.8K0.01%−57−19.4%Reduced
Colonial Trust Advisors237$105.8K0.01%+64+37.0%Added
Ares Financial Consulting, LLC240$107.3K0.08%+167+228.8%Added
Trust Co of Toledo NA245$109.4K0.01%+1+0.4%Added
NBC Securities, Inc.247$110.3K0.01%+1+0.4%Added
Capula Management Ltd247$110.3K0.00%+247New
Oakworth Capital, Inc.249$111.2K0.01%+135+118.4%Added
WPG Advisers, LLC252$112.5K0.08%+7+2.9%Added
Acumen Wealth Advisors, LLC254$113.4K0.03%+1+0.4%Added
Owl Creek Wealth Partners LLC256$114.3K0.04%+256New
MV Capital Management, Inc.257$114.8K0.01%+68+36.0%Added
Munich Reinsurance Co Stock Corp in Munich260$116.1K0.00%+260New
Global Trust Asset Management, LLC272$121.5K0.05%−158−36.7%Reduced
Hilltop National Bank272$121.5K0.03%00.0%Unchanged
Roble, Belko & Company, Inc279$125.0K0.02%00.0%Unchanged
Twin Peaks Wealth Advisors, LLC280$125.0K0.03%+280New
Ritter Daniher Financial Advisory LLC282$125.9K0.02%00.0%Unchanged
Tripletail Wealth Management, LLC290$127.2K0.17%00.0%Unchanged
Key Financial Inc290$129.5K0.02%00.0%Unchanged
Vanguard National Trust Co294$131.3K0.01%+294New
McMillan Office, Inc.300$134.0K0.02%00.0%Unchanged
Covestor Ltd303$136.0K0.09%−181−37.4%Reduced
Root Financial Partners, LLC305$136.2K0.01%+36+13.4%Added
Toth Financial Advisory Corp306$136.6K0.02%+76+33.0%Added
TFC Financial Management307$137.1K0.02%00.0%Unchanged
Wealth Enhancement Trust Services, Inc.308$137.5K0.02%−52−14.4%Reduced
Goodman Advisory Group, LLC311$138.9K0.04%−68−17.9%Reduced
Clean Yield Group322$143.8K0.04%00.0%Unchanged
Highline Wealth Partners LLC322$143.8K0.04%+297+1,188.0%Added
Addison Advisors LLC328$146.5K0.03%+2+0.6%Added
Johnson Financial Group, Inc.338$150.9K0.01%−29−7.9%Reduced
Deseret Mutual Benefit Administrators342$152.7K0.05%−54−13.6%Reduced
Signature Equity Partners, LLC347$154.9K0.08%+303+688.6%Added
Paradigm Asset Management Co LLC350$156.3K0.04%00.0%Unchanged
Bard Associates Inc350$156.3K0.04%00.0%Unchanged
Eastern Bank362$161.6K0.00%+40+12.4%Added
Wall Street Financial Group, Inc.365$163.0K0.10%−96−20.8%Reduced
Bryn Mawr Trust Co372$166.1K0.00%−257−40.9%Reduced
Timothy G. Youngquist 2020 Irrevocable Trust376$167.9K0.08%+376New
Washington Trust Advisors, Inc.377$168.3K0.01%−106−21.9%Reduced