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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Sofinnova Investments, Inc.0$00.00%−164,594−100.0%Sold out
Worldquant Millennium Advisors LLC0$00.00%−108,002−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−98,360−100.0%Sold out
Tang Capital Management LLC0$00.00%−80,000−100.0%Sold out
ARK Investment Management LLCSuperinvestorARK Invest0$00.00%−26,100−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−18,054−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−17,416−100.0%Sold out
Prevail Innovative Wealth Advisors, LLC0$00.00%−15,613−100.0%Sold out
Walleye Trading LLC0$00.00%−13,339−100.0%Sold out
Cornerstone Advisors, LLC0$00.00%−10,700−100.0%Sold out
Winton Group Ltd0$00.00%−10,623−100.0%Sold out
DKRT Investments Corp.0$00.00%−10,000−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−9,000−100.0%Sold out
Davidson Capital Management Inc.0$00.00%−8,759−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−7,231−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−5,641−100.0%Sold out
Dymon Asia Capital (Singapore) Pte. Ltd.0$00.00%−4,200−100.0%Sold out
Quantitative Investment Management, LLC0$00.00%−3,657−100.0%Sold out
F&V Capital Management, LLC0$00.00%−3,645−100.0%Sold out
Grange Capital, LLC0$00.00%−3,279−100.0%Sold out
Forum Financial Management, LP0$00.00%−2,415−100.0%Sold out
Laurion Capital Management LP0$00.00%−2,200−100.0%Sold out
Applied Finance Capital Management, LLC0$00.00%−2,106−100.0%Sold out
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors0$00.00%−2,027−100.0%Sold out
Sage Mountain Advisors LLC0$00.00%−1,997−100.0%Sold out
IFG Advisory, LLC0$00.00%−1,941−100.0%Sold out
Kessler Investment Group, LLC0$00.00%−1,373−100.0%Sold out
Bannerstone Capital Management, LLC0$00.00%−1,342−100.0%Sold out
Quadrature Capital Ltd0$00.00%−1,303−100.0%Sold out
Davy Global Fund Management Ltd0$00.00%−1,191−100.0%Sold out
WBI Investments0$00.00%−1,114−100.0%Sold out
Cynosure Management, LLC0$00.00%−1,079−100.0%Sold out
Albion Financial Group0$00.00%−1,077−100.0%Sold out
Flow Traders U.S. LLC0$00.00%−1,029−100.0%Sold out
Strategic Family Wealth Counselors, L.L.C.0$00.00%−987−100.0%Sold out
Willner & Heller, LLC0$00.00%−893−100.0%Sold out
Gallacher Capital Management LLC0$00.00%−827−100.0%Sold out
Atalanta Sosnoff Capital, LLC0$00.00%−773−100.0%Sold out
One Charles Private Wealth Services, LLC0$00.00%−767−100.0%Sold out
Clear Street Markets LLC0$00.00%−763−100.0%Sold out
DRW Securities, LLC0$00.00%−746−100.0%Sold out
GK Wealth Management LLC0$00.00%−732−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−706−100.0%Sold out
Sivia Capital Partners, LLC0$00.00%−678−100.0%Sold out
Center For Asset Management LLC0$00.00%−677−100.0%Sold out
Mason & Associates Inc0$00.00%−665−100.0%Sold out
Quest Partners LLC0$00.00%−661−100.0%Sold out
Kestra Investment Management, LLC0$00.00%−658−100.0%Sold out
Sentry Investment Management LLC0$00.00%−640−100.0%Sold out
Signet Private Wealth LLC0$00.00%−589−100.0%Sold out
McAdam, LLC0$00.00%−569−100.0%Sold out
Axxcess Wealth Management, LLC0$00.00%−565−100.0%Sold out
Blackhawk Capital Partners LLC.0$00.00%−541−100.0%Sold out
Collaborative Wealth Managment Inc.0$00.00%−534−100.0%Sold out
Spirepoint Private Client, LLC0$00.00%−502−100.0%Sold out
WSFS Capital Management, LLC0$00.00%−494−100.0%Sold out
SeaCrest Wealth Management, LLC0$00.00%−459−100.0%Sold out
SevenBridge Financial Group, LLC0$00.00%−465−100.0%Sold out
Investment Advisory Group, LLC0$00.00%−489−100.0%Sold out
Commonwealth Financial Services, LLC0$00.00%−485−100.0%Sold out
Capstone Capital Management Ltd0$00.00%−484−100.0%Sold out
Bourgeon Capital Management LLC0$00.00%−483−100.0%Sold out
Jupiter Asset Management Ltd0$00.00%−480−100.0%Sold out
Fieldview Capital Management, LLC0$00.00%−473−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−463−100.0%Sold out
Hutchens & Kramer Investment Management Group, LLC0$00.00%−457−100.0%Sold out
Stratos Wealth Advisors, LLC0$00.00%−454−100.0%Sold out
PKS Advisory Services, LLC0$00.00%−453−100.0%Sold out
Englebert Financial Advisers, LLC0$00.00%−453−100.0%Sold out
Hansen & Associates Financial Group, Inc.0$00.00%−441−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−449−100.0%Sold out
Blalock Williams, LLC0$00.00%−444−100.0%Sold out
Reflection Asset Management0$00.00%−288−100.0%Sold out
Garton & Associates Financial Advisors LLC0$00.00%−278−100.0%Sold out
Kempen Capital Management N.V.0$00.00%−257−100.0%Sold out
QVR LLC0$00.00%−253−100.0%Sold out
Greenline Wealth Management LLC0$00.00%−176−100.0%Sold out
State of Wyoming0$00.00%−159−100.0%Sold out
Cape Investment Advisory, Inc.0$00.00%−115−100.0%Sold out
American National Bank0$00.00%−76−100.0%Sold out
Solstein Capital, LLC0$00.00%−67−100.0%Sold out
Eagle Bay Advisors LLC0$00.00%−65−100.0%Sold out
Howard Hughes Medical Institute0$00.00%−55−100.0%Sold out
Center for Financial Planning, Inc.0$00.00%−50−100.0%Sold out
Modus Advisors, LLC0$00.00%−32−100.0%Sold out
Innovative Advisory Group, LLC0$00.00%−30−100.0%Sold out
Legacy Bridge, LLC0$00.00%−24−100.0%Sold out
Wealth Watch Advisors, INC0$00.00%−24−100.0%Sold out
Quattro Advisors LLC0$00.00%−24−100.0%Sold out
Turning Point Benefit Group, Inc.0$00.00%−24−100.0%Sold out
Optiver Holding B.V.0$00.00%−21−100.0%Sold out
Missouri Trust & Investment Co0$00.00%−20−100.0%Sold out
Optima Capital LLC0$00.00%−20−100.0%Sold out
eCIO, Inc.0$00.00%−15−100.0%Sold out
Laurel Wealth Advisors LLC0$00.00%−10−100.0%Sold out
Sunrise Financial Services, LLC0$00.00%−10−100.0%Sold out
Tucker Asset Management LLC0$00.00%−9−100.0%Sold out
Winnow Wealth LLC0$00.00%−8−100.0%Sold out
Luken Investment Analytics, LLC0$00.00%−2−100.0%Sold out
Strategic Advocates LLC0$00.00%−1−100.0%Sold out