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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 1 sale; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Fisher Asset Management, LLC31,158$13.9M0.00%+5,940+23.6%Added
Elo Mutual Pension Insurance Co31,378$14.0M0.23%−235−0.7%Reduced
Captrust Financial Advisors32,092$14.3M0.03%+18,288+132.5%Added
State of Alaska, Department of Revenue33,180$14.8M0.16%+265+0.8%Added
MML Investors Services, LLC33,419$14.9M0.04%−4,585−12.1%Reduced
Ilmarinen Mutual Pension Insurance Co33,800$15.1M0.12%−5,000−12.9%Reduced
Vestcor Inc34,019$15.2M0.42%−2,671−7.3%Reduced
McRae Capital Management Inc34,123$15.2M3.16%−1,435−4.0%Reduced
Allianz Asset Management GmbH34,339$15.3M0.02%−1,937−5.3%Reduced
British Columbia Investment Management Corp34,971$15.6M0.09%−10,525−23.1%Reduced
Fideuram - Intesa Sanpaolo Private Banking S.P.A.34,991$15.6M0.55%+3,710+11.9%Added
Galvin, Gaustad & Stein, LLC35,233$15.7M1.26%+924+2.7%Added
Bank of Nova Scotia35,361$15.8M0.03%−62,559−63.9%Reduced
Y-Intercept (Hong Kong) Ltd35,829$16.0M0.30%+35,829New
Caxton Associates LLP36,026$16.1M0.37%+36,026New
Shelton Capital Management36,379$16.2M0.36%−862−2.3%Reduced
Teachers Retirement System of the State of Kentucky36,725$16.4M0.13%−3,598−8.9%Reduced
Aristotle Atlantic Partners, LLC37,532$16.8M0.78%−859−2.2%Reduced
Bailard, Inc.37,862$16.9M0.39%+3,887+11.4%Added
New York Life Investment Management LLC38,069$17.0M0.14%+1,251+3.4%Added
Segall Bryant & Hamill, LLC38,073$17.0M0.24%−1,746−4.4%Reduced
Apollon Wealth Management, LLC38,595$17.2M0.28%+9,400+32.2%Added
Wealth Enhancement Advisory Services, LLC40,668$17.4M0.04%−40,578−49.9%Reduced
Police & Firemen's Retirement System of New Jersey39,061$17.4M0.15%−412−1.0%Reduced
Ossiam39,357$17.6M0.31%+21,763+123.7%Added
Flputnam Investment Management Co39,498$17.6M0.26%+2,707+7.4%Added
William Blair Investment Management, LLC39,547$17.7M0.06%−188−0.5%Reduced
Integral Health Asset Management, LLC40,000$17.9M0.95%+40,000New
Balyasny Asset Management LLC40,137$17.9M0.04%−73,351−64.6%Reduced
Macquarie Group Ltd40,236$18.0M0.11%−4,500−10.1%Reduced
Tweedy, Browne Co LLC40,387$18.0M1.43%+1,239+3.2%Added
Illinois Municipal Retirement Fund40,573$18.1M0.23%−6,213−13.3%Reduced
Banco Bilbao Vizcaya Argentaria, S.A.40,778$18.1M0.13%−53,059−56.5%Reduced
Public Sector Pension Investment Board41,177$18.4M0.06%+8,326+25.3%Added
Utah Retirement Systems41,265$18.4M0.19%−1,225−2.9%Reduced
JustInvest LLC41,623$18.6M0.18%+2,458+6.3%Added
Gradient Investments LLC41,736$18.6M0.29%−1,859−4.3%Reduced
Empowered Funds, LLC41,737$18.6M0.12%+26,931+181.9%Added
Motley Fool Wealth Management, LLC42,836$19.1M2.16%−16,701−28.1%Reduced
Rhenman & Partners Asset Management AB43,485$19.4M2.40%+9,230+26.9%Added
Lido Advisors, LLC43,511$19.4M0.08%−10,086−18.8%Reduced
Varma Mutual Pension Insurance Co43,626$19.5M0.11%+3,000+7.4%Added
China Universal Asset Management Co., Ltd.43,902$19.6M1.48%−4,145−8.6%Reduced
Advisor Group Holdings, Inc.43,972$19.6M0.03%+220+0.5%Added
W.G. Shaheen & Associates DBA Whitney & Co44,117$19.7M1.64%−47−0.1%Reduced
Pathstone Holdings, LLC44,262$19.8M0.08%−1,342−2.9%Reduced
Zurich Insurance Group Ltd44,618$19.9M0.16%−4,081−8.4%Reduced
Martingale Asset Management L P44,750$20.0M0.50%+1,529+3.5%Added
Hudson Bay Capital Management LP45,000$20.1M0.12%−119,518−72.6%Reduced
Skandinaviska Enskilda Banken AB (publ)46,000$20.5M0.47%−128,466−73.6%Reduced
C WorldWide Group Holding A/S46,057$20.6M0.44%00.0%Unchanged
Wealthfront Advisers LLC46,395$20.7M0.05%+3,226+7.5%Added
USS Investment Management Ltd47,128$21.0M0.09%+1,735+3.8%Added
Natixis48,192$21.5M0.09%−12,026−20.0%Reduced
PensionDanmark Pensionsforsikringsaktieselskab49,204$22.0M0.21%−177−0.4%Reduced
Sanctuary Advisors, LLC49,360$22.0M0.12%−444−0.9%Reduced
BI Asset Management Fondsmaeglerselskab A/S49,531$22.1M0.23%+39,005+370.6%Added
Citizens Financial Group Inc49,824$22.2M0.31%+6,421+14.8%Added
Hallmark Capital Management Inc50,139$22.4M1.44%−812−1.6%Reduced
Caisse de Depot Et Placement du Quebec50,917$22.7M0.04%−62,851−55.2%Reduced
IFM Investors Pty Ltd51,070$22.8M0.19%+1,290+2.6%Added
Davidson Investment Advisors51,222$22.9M0.99%−13,005−20.2%Reduced
Hemenway Trust Co LLC51,499$23.0M1.85%+482+0.9%Added
Cullinan Associates Inc51,762$23.1M1.87%+450+0.9%Added
Rakuten Investment Management, Inc.52,690$23.4M0.05%+5,505+11.7%Added
Amalgamated Bank53,269$23.8M0.18%−1,851−3.4%Reduced
Retirement Systems of Alabama53,938$24.1M0.08%−38−0.1%Reduced
Rafferty Asset Management, LLC54,572$24.4M0.10%−13,510−19.8%Reduced
Reynders McVeigh Capital Management, LLC54,664$24.4M1.23%+759+1.4%Added
Commonwealth Equity Services, LLC54,972$24.5M0.03%+829+1.5%Added
Zacks Investment Management55,082$24.6M0.20%−1,544−2.7%Reduced
Pinebridge Investments LLC55,100$24.6M0.21%+52,199+1,799.3%Added
Edgemoor Investment Advisors, Inc.55,415$24.7M1.95%+576+1.1%Added
Smith Group Asset Management, LLC55,746$24.9M1.27%+3,695+7.1%Added
Atwood & Palmer Inc55,753$24.9M1.40%+361+0.7%Added
Beacon Investment Advisory Services, Inc.56,104$25.1M1.04%−17,989−24.3%Reduced
SG Americas Securities, LLC56,982$25.4M0.03%−58,917−50.8%Reduced
Moody Lynn & Lieberson, LLC57,640$25.7M1.44%+2,648+4.8%Added
Foster Dykema Cabot & Partners, LLC57,792$25.8M1.64%−552−0.9%Reduced
Nisa Investment Advisors, LLC58,183$26.0M0.10%+1,589+2.8%Added
Hardman Johnston Global Advisors LLC58,357$26.1M1.24%−5,449−8.5%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys59,167$26.4M0.13%+151+0.3%Added
Assetmark, Inc59,954$26.8M0.05%−30,529−33.7%Reduced
Ofi Invest Asset Management69,233$26.8M0.35%+109+0.2%Added
O'Shaughnessy Asset Management, LLC61,867$27.6M0.14%+14,622+30.9%Added
Trillium Asset Management, LLC99,762$28.1M0.93%+37,069+59.1%Added
Sumitomo Mitsui DS Asset Management Company, Ltd63,822$28.5M0.23%+1,061+1.7%Added
CIBC Bancorp USA Inc.63,952$28.6M0.04%+63,952New
GF Fund Management Co. Ltd.64,591$28.8M0.48%−820−1.3%Reduced
Los Angeles Capital Management LLC64,937$29.0M0.11%−228,364−77.9%Reduced
ING Groep NV65,425$29.2M0.18%−15,704−19.4%Reduced
HighTower Advisors, LLC65,684$29.3M0.03%+18,125+38.1%Added
Gateway Investment Advisers LLC67,121$30.0M0.33%+1,013+1.5%Added
Daiwa Securities Group Inc.67,539$30.2M0.09%−3,056−4.3%Reduced
Holocene Advisors, LP67,618$30.2M0.07%+66,140+4,475.0%Added
Abn Amro Investment Solutions68,216$30.5M0.40%+49,146+257.7%Added
State of Michigan Retirement System69,123$30.9M0.16%−100−0.1%Reduced
Czech National Bank69,176$30.9M0.20%+2,274+3.4%Added
Arizona State Retirement System69,515$31.0M0.18%−2,778−3.8%Reduced
Xponance, Inc.70,714$31.6M0.22%+4,941+7.5%Added