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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Ashford Capital Management Inc9,078$4.05M0.50%+833+10.1%Added
Peloton Wealth Strategists9,140$4.08M1.65%+100+1.1%Added
Lombard Odier Asset Management (Switzerland) SA9,312$4.16M0.16%−2,380−20.4%Reduced
Group One Trading, L.P.9,357$4.18M0.14%+9,357New
Saudi Central Bank9,365$4.18M0.09%+9,365New
Cumberland Partners Ltd9,376$4.19M0.32%−231−2.4%Reduced
Tokio Marine Asset Management Co Ltd9,424$4.21M0.15%+100+1.1%Added
Vinva Investment Management Ltd9,531$4.22M0.05%−1,407−12.9%Reduced
Concurrent Investment Advisors, LLC9,484$4.23M0.05%−250−2.6%Reduced
Miracle Mile Advisors, LLC9,518$4.25M0.06%−316−3.2%Reduced
Level Four Advisory Services, LLC9,524$4.25M0.14%−29−0.3%Reduced
Sigma Investment Counselors Inc9,617$4.29M0.23%−404−4.0%Reduced
Tema ETFs LLC9,640$4.30M0.29%+28+0.3%Added
Parsons Capital Management Inc9,641$4.31M0.20%+150+1.6%Added
Machina Capital S.A.S.9,654$4.31M0.85%+4,590+90.6%Added
Kestra Private Wealth Services, LLC9,675$4.32M0.05%−763−7.3%Reduced
Howe & Rusling Inc9,721$4.34M0.28%+203+2.1%Added
NewEdge Wealth, LLC9,788$4.37M0.05%+1,386+16.5%Added
Sivik Global Healthcare LLC10,000$4.46M3.39%−3,770−27.4%Reduced
Fayez Sarofim & Co10,000$4.47M0.01%00.0%Unchanged
Oddo BHF Asset Management SAS10,151$4.53M0.18%−36,482−78.2%Reduced
HB Wealth Management, LLC10,287$4.59M0.03%+815+8.6%Added
Merit Financial Group, LLC10,335$4.62M0.03%+1,368+15.3%Added
AG2R la Mondiale Gestion D'Actifs10,381$4.64M0.21%+6+0.1%Added
Mirova10,383$4.64M0.19%+10,383New
Keybank National Association10,402$4.64M0.02%+272+2.7%Added
MUFG Securities EMEA plc10,413$4.65M0.07%+12+0.1%Added
Northwest Bancshares, Inc.10,418$4.65M0.93%−218−2.0%Reduced
Joseph Group Capital Management10,514$4.69M1.17%+25+0.2%Added
Morse Asset Management, Inc10,565$4.72M0.98%+142+1.4%Added
Generali Investments CEE, investicni spolecnost, a.s.10,599$4.73M0.25%+108+1.0%Added
E Fund Management Co., Ltd.10,816$4.83M0.14%+10,816New
CSM Advisors, LLC10,838$4.84M0.12%+10,838New
PKO Investment Management Joint-Stock Co11,000$4.91M0.41%−200−1.8%Reduced
Superstring Capital Management LP11,010$4.92M3.51%+11,010New
Benjamin Edwards Inc11,117$4.97M0.05%+24+0.2%Added
Privium Fund Management B.V.11,355$5.07M1.06%+2,000+21.4%Added
New Age Alpha Advisors, LLC11,418$5.10M0.24%−1,204−9.5%Reduced
Delaney Dennis R11,649$5.20M1.84%+4,680+67.2%Added
Metis Global Partners, LLC11,667$5.21M0.13%−999−7.9%Reduced
Siemens Fonds Invest GmbH11,678$5.21M0.30%+466+4.2%Added
New Mexico Educational Retirement Board11,700$5.22M0.16%00.0%Unchanged
Traynor Capital Management, Inc.11,806$5.23M0.31%+39+0.3%Added
Brinker Capital Investments, LLC11,862$5.30M0.05%−289−2.4%Reduced
Laird Norton Trust Company, LLC11,890$5.31M0.12%+133+1.1%Added
Park Avenue Securities LLC11,911$5.32M0.04%−1,896−13.7%Reduced
Northwest & Ethical Investments L.P.11,942$5.33M0.12%+838+7.5%Added
Andrew Hill Investment Advisors, Inc.11,955$5.34M4.76%−453−3.7%Reduced
Covenant Asset Management, LLC12,081$5.39M1.11%+192+1.6%Added
Greenwood Capital Associates LLC12,101$5.40M0.60%−221−1.8%Reduced
Chicago Capital, LLC12,119$5.41M0.15%−26−0.2%Reduced
United Capital Financial Advisers, LLC12,226$5.46M0.03%+149+1.2%Added
Slow Capital, Inc.12,307$5.50M0.71%+963+8.5%Added
Ameritas Investment Partners, Inc.12,563$5.61M0.17%−2,618−17.2%Reduced
Kidder Stephen W12,716$5.68M1.67%+257+2.1%Added
Maryland State Retirement & Pension System12,846$5.74M0.12%00.0%Unchanged
Fisher Funds Management LTD12,898$5.76M0.17%00.0%Unchanged
Compagnie Lombard Odier SCmA13,081$5.84M0.07%+416+3.3%Added
Kayne Anderson Rudnick Investment Management LLC13,085$5.84M0.02%+1,440+12.4%Added
Princeton Global Asset Management LLC13,263$5.92M0.97%+104+0.8%Added
Sterling Capital Management LLC13,338$5.96M0.11%−4,204−24.0%Reduced
Bridgewater Associates, LP13,357$5.96M0.03%−14,131−51.4%Reduced
M&T Bank Corp13,660$6.10M0.02%−1,072−7.3%Reduced
Liontrust Investment Partners LLP13,691$6.11M0.10%−1,355−9.0%Reduced
TD Waterhouse Canada Inc.13,774$6.14M0.02%+8,043+140.3%Added
Engineers Gate Manager LP13,818$6.17M0.08%+9,154+196.3%Added
Exchange Traded Concepts, LLC13,875$6.20M0.05%+1,850+15.4%Added
Tower Research Capital LLC (TRC)13,904$6.21M0.16%+325+2.4%Added
Kestra Advisory Services, LLC13,950$6.23M0.02%−481−3.3%Reduced
Knuff & Co LLC13,981$6.24M1.88%−216−1.5%Reduced
Ci Investments Inc.14,000$6.25M0.03%−35,891−71.9%Reduced
Hamilton Capital Partners Inc.14,053$6.28M0.21%−167−1.2%Reduced
Dai-Ichi Life Insurance Company, Ltd14,165$6.33M0.18%−373−2.6%Reduced
Hartford Investment Management Co14,489$6.47M0.20%−173−1.2%Reduced
Atlantic Union Bankshares Corp14,494$6.47M0.12%+261+1.8%Added
Princeton Capital Management LLC14,531$6.49M1.77%+22+0.2%Added
First Horizon Corp14,535$6.49M0.27%+2,380+19.6%Added
Aptus Capital Advisors, LLC14,644$6.54M0.05%−1,798−10.9%Reduced
Sequoia Financial Advisors, LLC14,898$6.65M0.04%+1,302+9.6%Added
ADAR1 Capital Management, LLC15,075$6.73M0.40%+1,359+9.9%Added
Trexquant Investment LP15,171$6.77M0.05%−30,882−67.1%Reduced
Callan Family Office, LLC15,262$6.82M0.15%+822+5.7%Added
Generali Asset Management SPA SGR15,300$6.83M0.14%−3,238−17.5%Reduced
Mizuho Securities USA LLC15,355$6.86M0.16%−3,119−16.9%Reduced
Torray LLC15,386$6.87M1.01%−80−0.5%Reduced
Puzo Michael J15,414$6.88M2.00%+43+0.3%Added
Nia Impact Advisors, LLC15,490$6.92M3.08%−2,148−12.2%Reduced
XTX Topco Ltd15,632$6.98M0.12%+15,632New
Baldwin Investment Management, LLC15,662$6.99M0.82%+108+0.7%Added
Anderson Hoagland & Co15,734$7.03M0.60%00.0%Unchanged
Allworth Financial LP15,803$7.06M0.03%+1,767+12.6%Added
Cambridge Investment Research Advisors, Inc.15,955$7.12M0.02%+1,598+11.1%Added
Federation des caisses Desjardins du Quebec15,955$7.12M0.03%+2,939+22.6%Added
Vident Advisory, LLC16,063$7.17M0.06%+2,378+17.4%Added
NLB Skladi, upravljanje premozenja, d.o.o.16,303$7.28M0.35%+1,152+7.6%Added
Silvercrest Asset Management Group LLC16,358$7.30M0.05%+330+2.1%Added
Leuthold Group, LLC16,455$7.35M0.78%+48+0.3%Added
Fulcrum Capital LLC16,496$7.37M1.60%−120−0.7%Reduced
Blair William & Co16,541$7.39M0.02%+451+2.8%Added
Cullen/Frost Bankers, Inc.16,568$7.40M0.08%+15,978+2,708.1%Added