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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Brown Brothers Harriman & Co5,838$2.61M0.01%+1,320+29.2%Added
Legacy Capital Wealth Management, LLC5,849$2.61M1.53%+806+16.0%Added
Westview Management dba Westview Investment Advisors5,854$2.61M1.36%−430−6.8%Reduced
Virtus Investment Advisers, Inc.5,869$2.62M0.72%+4,358+288.4%Added
Harbour Capital Advisors, LLC5,994$2.62M0.50%+61+1.0%Added
Freedom Day Solutions, LLC5,915$2.64M0.71%−112−1.9%Reduced
Camden Capital, LLC5,929$2.65M0.17%−510−7.9%Reduced
Bokf, NA5,935$2.65M0.04%+68+1.2%Added
Plato Investment Management Ltd5,935$2.65M0.18%00.0%Unchanged
Hall Laurie J Trustee5,960$2.66M0.94%−70−1.2%Reduced
Cohen Klingenstein LLC6,000$2.68M0.09%00.0%Unchanged
Patriot Financial Group Insurance Agency, LLC6,124$2.73M0.15%+3,090+101.8%Added
RSM US Wealth Management LLC6,166$2.75M0.03%−842−12.0%Reduced
Griffin Asset Management, Inc.6,175$2.76M0.31%−20−0.3%Reduced
Meeder Advisory Services, Inc.6,197$2.77M0.12%+132+2.2%Added
Skopos Labs, Inc.6,245$2.79M0.09%+2,006+47.3%Added
Lighthouse Financial LLC6,277$2.80M1.69%+2,547+68.3%Added
Nwam LLC6,332$2.83M0.16%+1,294+25.7%Added
Sand Hill Global Advisors, LLC6,369$2.84M0.10%+1,193+23.0%Added
Kinneret Advisory, LLC6,397$2.86M0.27%−284−4.3%Reduced
South Dakota Investment Council6,400$2.86M0.05%00.0%Unchanged
Wahed Invest LLC6,415$2.86M0.37%−356−5.3%Reduced
Thompson Siegel & Walmsley LLC6,437$2.87M0.05%−261−3.9%Reduced
Perigon Wealth Management, LLC6,454$2.88M0.05%+410+6.8%Added
Condor Capital Management6,461$2.89M0.24%−26−0.4%Reduced
Boomfish Wealth Group, LLC6,463$2.89M1.54%+53+0.8%Added
Canada Post Corp Registered Pension Plan6,474$2.89M0.12%00.0%Unchanged
Freemont Management S.A.6,500$2.90M0.54%−700−9.7%Reduced
Coldstream Capital Management Inc6,537$2.92M0.04%+535+8.9%Added
Principal Securities, Inc.6,578$2.94M0.04%+259+4.1%Added
Channel Wealth LLC6,588$2.94M0.71%−18−0.3%Reduced
GAMMA Investing LLC6,592$2.94M0.14%+878+15.4%Added
Graphene Investments SAS6,600$2.95M1.98%−900−12.0%Reduced
Leavell Investment Management, Inc.6,660$2.97M0.12%+15+0.2%Added
Atomi Financial Group, Inc.6,666$2.98M0.09%+125+1.9%Added
B&L Asset Management LLC6,679$2.98M1.30%+442+7.1%Added
Vision Capital Management, Inc.6,699$2.99M0.38%+104+1.6%Added
Squarepoint Ops LLC6,752$3.02M0.01%−382,268−98.3%Reduced
Brighton Jones LLC6,756$3.02M0.07%+6,756New
Kentucky Retirement Systems Insurance Trust Fund6,768$3.02M0.21%00.0%Unchanged
Associated Banc-Corp6,815$3.04M0.08%−132−1.9%Reduced
North Star Asset Management Inc6,859$3.06M0.13%00.0%Unchanged
Securian Asset Management, Inc6,899$3.08M0.12%00.0%Unchanged
Montchanin Asset Management, LLC6,932$3.10M3.29%+6,932New
Vestmark Advisory Solutions, Inc.6,957$3.11M0.03%−865−11.1%Reduced
Central Trust Co6,963$3.11M0.06%−400−5.4%Reduced
Glenview Trust Co6,995$3.12M0.05%−10−0.1%Reduced
DCF Advisers, LLC7,000$3.13M1.18%+1,000+16.7%Added
MUFG Securities Americas Inc.7,028$3.14M0.20%+193+2.8%Added
Univest Financial Corp7,063$3.15M0.18%+966+15.8%Added
RMR Wealth Builders7,110$3.17M0.25%+1,321+22.8%Added
RDA Financial Network7,183$3.21M0.80%+344+5.0%Added
First National Bank of Mount Dora, Trust Investment Services7,211$3.22M0.70%+999+16.1%Added
Summit Trail Advisors, LLC7,247$3.24M0.05%+2,190+43.3%Added
Commerzbank Aktiengesellschaft7,281$3.25M0.07%−810−10.0%Reduced
Zions Bancorporation, National Association7,301$3.26M0.21%−6,457−46.9%Reduced
Johnson Investment Counsel Inc7,343$3.28M0.03%−383−5.0%Reduced
Marex Group plc7,368$3.29M0.03%−74−1.0%Reduced
EagleClaw Capital Managment, LLC7,385$3.30M0.46%00.0%Unchanged
North Dakota State Investment Board7,450$3.33M0.14%−1,371−15.5%Reduced
Bamco Inc7,500$3.35M0.01%+2,300+44.2%Added
Commerce Bank7,535$3.36M0.02%+536+7.7%Added
Hedeker Wealth, LLC7,626$3.41M0.72%+2,961+63.5%Added
Virtu Financial LLC7,634$3.41M0.14%+6,141+411.3%Added
Brown Advisory Inc7,653$3.42M0.01%−121−1.6%Reduced
Sectoral Asset Management Inc7,007$3.46M2.86%−998−12.5%Reduced
Sumitomo Life Insurance Co7,755$3.46M0.08%−371−4.6%Reduced
Crestwood Advisors Group LLC7,756$3.46M0.06%−247−3.1%Reduced
Twin Tree Management, LP7,769$3.47M0.73%+7,769New
Dempze Nancy E7,810$3.49M1.92%+752+10.7%Added
Baldwin Brothers Inc7,824$3.49M0.25%00.0%Unchanged
J.P. Marvel Investment Advisors, LLC7,855$3.51M0.50%00.0%Unchanged
Cresset Asset Management, LLC7,860$3.51M0.02%+305+4.0%Added
Notis-McConarty Edward7,885$3.52M1.75%+31+0.4%Added
Stenger Family Office, LLC7,900$3.53M0.64%+577+7.9%Added
Gabelli Funds LLC7,920$3.54M0.02%−64−0.8%Reduced
Simplify Asset Management Inc.7,936$3.54M0.05%−9,556−54.6%Reduced
Emerald Investment Advisers, LLC8,012$3.58M0.32%+8,012New
Linden Thomas Advisory Services, LLC8,123$3.63M0.35%−282−3.4%Reduced
Northwestern Mutual Investment Management Company, LLC8,127$3.63M0.06%+20+0.2%Added
Elefante Mark B8,141$3.64M2.00%+1,126+16.1%Added
Bensler, LLC8,256$3.69M0.38%−490−5.6%Reduced
MASTERINVEST Kapitalanlage GmbH8,293$3.70M0.38%+2,749+49.6%Added
Sepio Capital, LP8,294$3.70M0.20%−571−6.4%Reduced
Strategic Advisors LLC8,294$3.70M0.62%−481−5.5%Reduced
Aureus Asset Management, LLC8,395$3.75M0.25%+2,253+36.7%Added
Private Advisor Group, LLC8,433$3.77M0.02%−261−3.0%Reduced
Bessemer Group Inc8,565$3.83M0.01%+973+12.8%Added
CWM, LLC8,609$3.84M0.01%+1,266+17.2%Added
EP Wealth Advisors, LLC8,637$3.86M0.02%−309−3.5%Reduced
Empirical Finance, LLC8,694$3.88M0.18%−17−0.2%Reduced
Envestnet Portfolio Solutions, Inc.8,697$3.88M0.02%−7,772−47.2%Reduced
Baird Financial Group, Inc.8,771$3.92M0.01%+2,260+34.7%Added
E. Ohman J:or Asset Management AB8,823$3.94M0.10%−200−2.2%Reduced
Northwestern Mutual Wealth Management Co8,856$3.95M0.00%+556+6.7%Added
Alphadyne Asset Management LP8,922$3.98M0.52%+8,922New
Banque Cantonale Vaudoise8,927$3.99M0.15%−2,149−19.4%Reduced
Meiji Yasuda Asset Management Co Ltd.8,940$3.99M0.20%−281−3.0%Reduced
Little House Capital LLC8,961$4.00M1.03%+22+0.2%Added
Mark Sheptoff Financial Planning, LLC9,546$4.05M2.14%−700−6.8%Reduced