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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
AE Wealth Management LLC3,924$1.75M0.01%+1,194+43.7%Added
MRP Capital Investments, LLC3,925$1.75M1.53%+3,921+98,025.0%Added
Choate Investment Advisors3,937$1.76M0.03%−39−1.0%Reduced
Alaethes Wealth LLC3,949$1.76M0.51%+162+4.3%Added
Howard Capital Management Inc.3,970$1.77M0.03%−5,304−57.2%Reduced
Lipe & Dalton3,996$1.78M0.93%00.0%Unchanged
Qube Research & Technologies Ltd3,998$1.79M0.00%+3,998New
Mitsubishi UFJ Asset Management (UK) Ltd.4,000$1.79M0.92%+4,000New
Jones Kertz & Associates, Inc.4,004$1.79M0.95%00.0%Unchanged
Woodstock Corp4,005$1.79M0.16%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.4,029$1.80M0.06%−783−16.3%Reduced
Tiaa-Cref Individual & Institutional Services, LLC4,062$1.81M0.01%+4,062New
JT Stratford LLC4,082$1.82M0.23%−12−0.3%Reduced
Mission Wealth Management, LP4,095$1.83M0.04%+39+1.0%Added
S&CO Inc4,103$1.83M0.11%00.0%Unchanged
Impax Asset Management Group plc4,134$1.85M0.01%−488−10.6%Reduced
McGuire Investment Group, LLC4,139$1.85M0.21%−314−7.1%Reduced
MWA Asset Management4,143$1.85M1.01%+927+28.8%Added
MBM Wealth Consultants, LLC4,150$1.85M0.43%+225+5.7%Added
Meiji Yasuda America Inc4,159$1.86M0.46%−57−1.4%Reduced
Trustmark National Bank Trust Department4,189$1.87M0.12%−574−12.1%Reduced
TCW Group Inc4,191$1.87M0.01%+203+5.1%Added
J. Safra Sarasin Holding AG4,195$1.87M0.03%+1,195+39.8%Added
ICICI Prudential Asset Management Co Ltd4,209$1.88M0.23%+138+3.4%Added
Resources Investment Advisors, LLC.4,212$1.88M0.02%−2,180−34.1%Reduced
Waldron Private Wealth LLC4,221$1.88M0.07%+37+0.9%Added
Aigen Investment Management, LP4,238$1.89M0.49%+3,344+374.0%Added
Leonteq Securities AG4,260$1.90M0.12%−766−15.2%Reduced
Everence Capital Management Inc4,274$1.91M0.12%00.0%Unchanged
BNP Paribas4,291$1.92M0.06%−2,848−39.9%Reduced
Oppenheimer & Co Inc4,308$1.92M0.02%+36+0.8%Added
Texas Yale Capital Corp.4,344$1.94M0.06%+75+1.8%Added
Harrell Investment Partners, LLC4,349$1.94M0.46%−28−0.6%Reduced
Decatur Capital Management, Inc.4,357$1.95M0.89%−69−1.6%Reduced
Private Harbour Investment Management & Counsel, LLC4,383$1.96M2.15%−53−1.2%Reduced
Ascent Group, LLC4,410$1.97M0.07%−1,085−19.7%Reduced
GKV Capital Management Co., Inc.4,417$1.97M0.74%+112+2.6%Added
Mather Group, LLC.4,438$1.98M0.02%+13+0.3%Added
Bangor Savings Bank4,450$1.99M0.16%−126−2.8%Reduced
Nations Financial Group Inc,4,490$2.00M0.10%+202+4.7%Added
Smartleaf Asset Management LLC4,540$2.01M0.07%+555+13.9%Added
Hamrick Investment Counsel, llc4,509$2.01M1.12%+1,526+51.2%Added
IMC-Chicago, LLC4,533$2.02M0.03%+4,533New
SageGuard Financial Group, LLC4,578$2.04M0.32%−3,525−43.5%Reduced
Cooper Financial Group4,599$2.05M0.21%−742−13.9%Reduced
Integrated Wealth Concepts LLC4,668$2.08M0.02%−53−1.1%Reduced
Jain Global LLC4,677$2.09M0.03%−20,301−81.3%Reduced
Oak Associates, Ltd4,677$2.09M0.14%00.0%Unchanged
Torrey Growth & Income Advisors4,710$2.09M0.88%−9−0.2%Reduced
Financiere des Professionnels - Fonds d,investissement inc.4,685$2.09M0.12%+4,060+649.6%Added
Greenleaf Trust4,753$2.12M0.02%+11+0.2%Added
De Burlo Group Inc4,755$2.12M0.48%−30−0.6%Reduced
Cito Capital Group, LLC4,756$2.12M0.65%00.0%Unchanged
Farther Finance Advisors, LLC4,752$2.13M0.02%+331+7.5%Added
GLOBALT Investments LLC4,773$2.13M0.08%+30+0.6%Added
Westerkirk Capital Inc.4,802$2.14M0.23%−269−5.3%Reduced
Burney Co4,810$2.15M0.07%−658−12.0%Reduced
Portside Wealth Group, LLC4,824$2.15M0.29%+510+11.8%Added
Phoenix Holdings Ltd.4,833$2.16M0.02%+1,300+36.8%Added
Wealthcare Advisory Partners LLC4,842$2.16M0.04%−417−7.9%Reduced
Ritholtz Wealth Management4,850$2.17M0.04%+438+9.9%Added
Scotia Capital Inc.4,861$2.17M0.01%−304−5.9%Reduced
BDF-Gestion4,862$2.17M0.29%+4,862New
AlphaCentric Advisors LLC4,931$2.20M2.20%+268+5.7%Added
Future Fund LLC4,957$2.21M0.78%+154+3.2%Added
Oarsman Capital, Inc.4,983$2.23M0.28%+193+4.0%Added
Knollwood Investment Advisory, LLC4,988$2.23M0.22%00.0%Unchanged
Meiji Yasuda Life Insurance Co5,005$2.23M0.08%00.0%Unchanged
Central Pacific Bank - Trust Division5,026$2.24M0.29%00.0%Unchanged
TFR Capital, LLC.5,037$2.25M0.69%+11+0.2%Added
Aaron Wealth Advisors5,042$2.25M0.13%+117+2.4%Added
Cinctive Capital Management LP5,049$2.25M0.15%+5,049New
Strategic Wealth Partners, Ltd.5,058$2.26M0.16%+498+10.9%Added
LGT Fund Management Co Ltd.5,063$2.26M0.10%+5,063New
Hager Investment Management Services, LLC5,089$2.27M1.25%+5+0.1%Added
Evergreen Capital Management LLC5,107$2.28M0.05%+306+6.4%Added
Te Ahumairangi Investment Management Ltd5,135$2.29M0.38%00.0%Unchanged
D.A. Davidson & Co.5,139$2.29M0.01%−112−2.1%Reduced
Advisory Services Network, LLC5,218$2.33M0.03%+209+4.2%Added
Ballentine Partners, LLC5,247$2.34M0.03%−43−0.8%Reduced
Baader Bank INC5,280$2.36M0.23%−8,324−61.2%Reduced
Vise Technologies, Inc.5,259$2.38M0.05%00.0%Unchanged
Wedbush Securities Inc5,417$2.42M0.07%−144−2.6%Reduced
BLI - Banque de Luxembourg Investments5,500$2.46M0.07%00.0%Unchanged
Parallel Advisors, LLC5,522$2.47M0.04%+333+6.4%Added
Fiduciary Alliance LLC5,583$2.47M0.15%+755+15.6%Added
Signaturefd, LLC5,526$2.47M0.04%+221+4.2%Added
Highview Capital Management LLC5,574$2.49M0.90%+165+3.1%Added
Campbell & CO Investment Adviser LLC5,580$2.49M0.14%−4,278−43.4%Reduced
GAM Holding AG5,580$2.49M0.22%−3,972−41.6%Reduced
Nemes Rush Group LLC5,605$2.50M0.24%−132−2.3%Reduced
Glenmede Trust Co NA5,608$2.50M0.01%+269+5.0%Added
Gibbs Wealth Management5,647$2.52M0.33%+4,412+357.2%Added
Havemeyer Place LP5,655$2.53M0.29%+3,598+174.9%Added
Mediolanum International Funds Ltd5,705$2.53M0.03%+218+4.0%Added
V-Square Quantitative Management LLC5,706$2.55M0.27%+82+1.5%Added
Quadrant Capital Group LLC5,716$2.55M0.08%+866+17.9%Added
Wimmer Associates 1, LLC5,733$2.56M1.25%+207+3.7%Added
Illumine Investment Management, LLC5,782$2.58M1.98%−38−0.7%Reduced
Financial Advisors Network, Inc.5,827$2.60M0.36%+5,827New