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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Connecticut Wealth Management, LLC2,653$1.18M0.05%+5+0.2%Added
Crossmark Global Holdings, Inc.2,704$1.21M0.02%−93−3.3%Reduced
Adviser Investments LLC2,711$1.21M0.01%+74+2.8%Added
IFP Advisors, Inc2,720$1.21M0.03%−362−11.7%Reduced
Centaurus Financial, Inc.2,721$1.22M0.06%−215−7.3%Reduced
Park Circle Co2,764$1.23M1.17%00.0%Unchanged
Sowell Financial Services LLC2,775$1.24M0.05%−39−1.4%Reduced
Belpointe Asset Management LLC2,776$1.24M0.05%−1,404−33.6%Reduced
Capital Investment Advisory Services, LLC2,783$1.24M0.09%−179−6.0%Reduced
Simplicity Wealth,LLC2,821$1.26M0.07%+403+16.7%Added
Dakota Wealth Management2,829$1.26M0.03%+206+7.9%Added
Boston Private Wealth LLC2,844$1.27M0.08%−217−7.1%Reduced
Trust Asset Management LLC2,856$1.28M0.09%00.0%Unchanged
AdvisorNet Financial, Inc2,864$1.28M0.07%+596+26.3%Added
Columbia Asset Management2,889$1.29M0.25%+646+28.8%Added
Bluebird Wealth Management LLC2,898$1.29M1.32%−8−0.3%Reduced
Pure Financial Advisors, Inc.2,906$1.30M0.02%−204−6.6%Reduced
Employees Retirement System of Texas2,918$1.30M0.01%00.0%Unchanged
WP Advisors, LLC2,945$1.32M0.34%−73−2.4%Reduced
Stephens Inc2,951$1.32M0.02%−143−4.6%Reduced
United Asset Strategies, Inc.2,965$1.32M0.11%−45−1.5%Reduced
Arrow Financial Corp2,994$1.34M0.13%−91−2.9%Reduced
Codex Capital Asset Management L.L.C.3,000$1.34M0.52%−4,320−59.0%Reduced
Ingalls & Snyder LLC3,012$1.34M0.05%−215−6.7%Reduced
Harel Insurance Investments & Financial Services Ltd.3,014$1.35M0.01%+578+23.7%Added
Lifeworks Advisors, LLC3,022$1.35M0.17%+99+3.4%Added
AustralianSuper Pty Ltd3,032$1.35M0.01%00.0%Unchanged
Ashton Thomas Securities, LLC3,048$1.36M0.17%+146+5.0%Added
Nelson, Van Denburg & Campbell Wealth Management Group, LLC3,054$1.36M0.04%−248−7.5%Reduced
Waterloo Capital, L.P.3,068$1.37M0.10%−861−21.9%Reduced
Paradigm Financial Partners, LLC3,081$1.38M0.25%−1,214−28.3%Reduced
Hartford Funds Management Co LLC3,101$1.39M0.12%+28+0.9%Added
Legacy Financial Advisors, Inc.3,144$1.40M0.20%+169+5.7%Added
Murphy & Mullick Capital Management Corp3,148$1.41M1.04%−38−1.2%Reduced
FRG Family Wealth Advisors LLC3,150$1.41M0.23%00.0%Unchanged
Berkshire Asset Management LLC3,152$1.41M0.06%−227−6.7%Reduced
Brevan Howard Capital Management LP3,152$1.41M0.01%+3,152New
MN Wealth Advisors, LLC3,157$1.41M0.69%+7+0.2%Added
Strategy Asset Managers LLC3,164$1.41M0.23%−27−0.8%Reduced
Baker Tilly Wealth Management, LLC3,188$1.42M0.35%+79+2.5%Added
Avestar Capital, LLC3,194$1.43M0.10%+399+14.3%Added
Cravens & Co Advisors, LLC3,204$1.43M0.93%+407+14.6%Added
Procyon Private Wealth Partners, LLC3,209$1.43M0.07%+3+0.1%Added
Kentucky Retirement Systems19,299$1.43M0.11%+3,152+19.5%Added
Institute for Wealth Management, LLC.3,215$1.44M0.15%00.0%Unchanged
Shepherd Street Advisors LLC3,218$1.44M1.42%+223+7.4%Added
DSG Capital Advisors, LLC3,225$1.44M0.23%−155−4.6%Reduced
DoubleLine ETF Adviser LP3,233$1.44M0.55%+3,233New
Founders Financial Securities LLC3,259$1.46M0.08%−405−11.1%Reduced
Edgestream Partners, L.P.3,263$1.46M0.05%−3,440−51.3%Reduced
We Are One Seven, LLC3,265$1.46M0.03%+930+39.8%Added
Independent Advisor Alliance3,267$1.46M0.02%−33−1.0%Reduced
Ifrah Financial Services, Inc.3,277$1.46M0.39%−120−3.5%Reduced
Sculati Wealth Management, LLC3,280$1.46M0.54%−80−2.4%Reduced
Kovack Advisors, Inc.3,286$1.47M0.08%−2,905−46.9%Reduced
Stratos Wealth Partners, LTD.3,299$1.47M0.02%00.0%Unchanged
Frank, Rimerman Advisors LLC3,317$1.48M0.10%+35+1.1%Added
AssuredPartners Investment Advisors, LLC3,456$1.50M0.16%+3,456New
Wedmont Private Capital3,383$1.50M0.05%+165+5.1%Added
Generali Investments, Management Co LLC3,366$1.50M0.35%+1,019+43.4%Added
Richard Bernstein Advisors LLC3,367$1.50M0.04%00.0%Unchanged
Roberts Glore & Co Inc3,406$1.52M0.42%−284−7.7%Reduced
Panagora Asset Management Inc3,408$1.52M0.01%−77−2.2%Reduced
Nilsine Partners, LLC3,576$1.52M0.12%−205−5.4%Reduced
Arrowpoint Investment Partners (Singapore) Pte. Ltd.3,412$1.52M2.22%+48+1.4%Added
Meeder Asset Management Inc3,424$1.53M0.09%+2,799+447.8%Added
Prudent Man Advisors, LLC3,427$1.53M0.46%+1,298+61.0%Added
Clearstead Advisors, LLC3,427$1.53M0.01%−100−2.8%Reduced
Triglav Skladi, D.O.O.3,450$1.54M0.11%00.0%Unchanged
Tealwood Asset Management Inc3,489$1.56M0.71%+27+0.8%Added
Valeo Financial Advisors, LLC3,500$1.56M0.04%−1,182−25.2%Reduced
IPG Investment Advisors LLC3,503$1.56M0.27%+3,503New
Equitable Holdings, Inc.3,464$1.56M0.01%+1,294+59.6%Added
Mutual Advisors, LLC3,509$1.57M0.03%+33+0.9%Added
Advisory Resource Group3,527$1.57M0.27%−92−2.5%Reduced
GLR Partners, LLC3,538$1.58M0.86%+3,538New
Dynamic Advisor Solutions LLC3,549$1.58M0.05%−119−3.2%Reduced
Midwest Professional Planners, LTD.3,549$1.58M0.37%+25+0.7%Added
Moors & Cabot, Inc.3,556$1.59M0.07%+77+2.2%Added
Syon Capital LLC3,563$1.59M0.08%+355+11.1%Added
Icon Wealth Advisors, LLC3,765$1.59M0.10%+22+0.6%Added
Sagespring Wealth Partners, LLC3,634$1.62M0.03%+47+1.3%Added
Arkadios Wealth Advisors3,684$1.65M0.03%−281−7.1%Reduced
3Chopt Investment Partners, LLC3,695$1.65M0.38%−491−11.7%Reduced
111 Capital3,740$1.67M0.41%+848+29.3%Added
Cambria Investment Management, L.P.3,755$1.68M0.09%−830−18.1%Reduced
Norden Group LLC3,757$1.68M0.16%+389+11.5%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP3,857$1.68M0.02%−121−3.0%Reduced
SFMG, LLC3,821$1.71M0.12%−341−8.2%Reduced
Snowden Capital Advisors LLC3,833$1.71M0.05%−85−2.2%Reduced
LGT Group Foundation3,840$1.71M0.02%−682−15.1%Reduced
Diadema Partners LP3,840$1.71M0.71%−6,160−61.6%Reduced
Savant Capital, LLC3,856$1.72M0.01%+449+13.2%Added
Mattson Financial Services, LLC3,861$1.72M0.41%−224−5.5%Reduced
Sound View Wealth Advisors Group, LLC3,863$1.72M0.12%−7−0.2%Reduced
Mattern Capital Management, LLC3,877$1.73M0.21%+188+5.1%Added
Capstone Investment Advisors, LLC3,895$1.74M0.01%+656+20.3%Added
Summit Global Investments3,896$1.74M0.10%−308−7.3%Reduced
Venturi Wealth Management, LLC3,897$1.74M0.08%−1,733−30.8%Reduced
Intrust Bank NA3,902$1.74M0.14%+429+12.4%Added