Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Fort Sheridan Advisors LLC | 2,002 | $907.6K | 0.12% | 00.0% | Unchanged |
| Allegheny Financial Group LTD | 2,003 | $908.1K | 0.13% | −6−0.3% | Reduced |
| Souders Financial Advisors | 2,006 | $909.4K | 0.10% | +242+13.7% | Added |
| Transcend Wealth Collective, LLC | 2,013 | $912.7K | 0.07% | −559−21.7% | Reduced |
| Advisory Alpha, LLC | 2,014 | $913.1K | 0.02% | +162+8.7% | Added |
| Rare Wolf Capital LLC | 2,015 | $913.5K | 0.57% | +2,015 | New |
| VestGen Advisors, LLC | 2,027 | $919.0K | 0.04% | −519−20.4% | Reduced |
| Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors | 2,027 | $919.0K | 0.11% | +697+52.4% | Added |
| Wealth Science Advisors LLC | 2,036 | $923.0K | 0.53% | +2,036 | New |
| Whittier Trust Co | 1,975 | $925.1K | 0.01% | +449+29.4% | Added |
| Ipswich Investment Management Co., Inc. | 2,043 | $926.2K | 0.21% | −40−1.9% | Reduced |
| Mitchell & Pahl Private Wealth, LLC | 2,049 | $928.9K | 0.39% | −95−4.4% | Reduced |
| Schmidt P J Investment Management Inc | 2,053 | $930.7K | 0.15% | −15−0.7% | Reduced |
| Havemeyer Place LP | 2,057 | $932.6K | 0.18% | +2,057 | New |
| First Manhattan Co | 2,059 | $933.5K | 0.00% | +479+30.3% | Added |
| PCM Encore, LLC | 2,067 | $937.0K | 0.20% | +2,067 | New |
| Grove Bank & Trust | 2,084 | $944.8K | 0.11% | +1,645+374.7% | Added |
| Change Path, LLC | 2,090 | $947.5K | 0.02% | −220−9.5% | Reduced |
| Generali Investments Towarzystwo Funduszy Inwestycyjnych | 2,100 | $952.1K | 0.46% | 00.0% | Unchanged |
| HM Payson & Co | 2,103 | $953.3K | 0.01% | −30−1.4% | Reduced |
| Pflug Koory, LLC | 2,103 | $953.4K | 0.44% | −34−1.6% | Reduced |
| Fortis Capital Advisors, LLC | 2,104 | $953.9K | 0.14% | +27+1.3% | Added |
| Evercore Wealth Management, LLC | 2,106 | $954.8K | 0.01% | 00.0% | Unchanged |
| Applied Finance Capital Management, LLC | 2,106 | $954.8K | 0.07% | +2,106 | New |
| Duncker Streett & Co Inc | 2,111 | $957.0K | 0.17% | −244−10.4% | Reduced |
| Presilium Private Wealth, LLC | 2,127 | $964.3K | 0.18% | +3+0.1% | Added |
| Prudent Man Advisors, LLC | 2,129 | $965.2K | 0.35% | +578+37.3% | Added |
| Westco Advisory Services Inc | 2,133 | $967.0K | 0.59% | +2,133 | New |
| Mount Yale Investment Advisors, LLC | 2,136 | $968.4K | 0.05% | +451+26.8% | Added |
| PFG Investments, LLC | 2,143 | $971.5K | 0.05% | +25+1.2% | Added |
| Argent Trust Co | 2,143 | $971.6K | 0.03% | −40−1.8% | Reduced |
| Fidelis Capital Partners, LLC | 2,155 | $977.0K | 0.07% | +136+6.7% | Added |
| Westport Asset Management Inc | 2,500 | $979.1K | 0.41% | 00.0% | Unchanged |
| Equitable Holdings, Inc. | 2,170 | $983.8K | 0.01% | −390−15.2% | Reduced |
| Waterfront Wealth Inc. | 2,081 | $985.1K | 0.19% | −10.0% | Reduced |
| Integrated Advisors Network LLC | 2,174 | $985.8K | 0.04% | −677−23.7% | Reduced |
| StoneX Group Inc. | 2,197 | $996.0K | 0.04% | +1,642+295.9% | Added |
| Laurion Capital Management LP | 2,200 | $997.4K | 0.07% | +2,200 | New |
| Impact Capital Partners LLC | 2,226 | $1.01M | 0.30% | +75+3.5% | Added |
| Columbia Asset Management | 2,243 | $1.02M | 0.18% | +1,690+305.6% | Added |
| PeakShares LLC | 2,244 | $1.02M | 0.99% | +2,244 | New |
| Kornitzer Capital Management Inc | 2,245 | $1.02M | 0.02% | −230−9.3% | Reduced |
| Nippon Life Global Investors Americas, Inc. | 2,250 | $1.02M | 0.04% | −580−20.5% | Reduced |
| Everhart Financial Group, Inc. | 2,251 | $1.02M | 0.09% | +163+7.8% | Added |
| AdvisorNet Financial, Inc | 2,268 | $1.03M | 0.05% | +69+3.1% | Added |
| Dorsey & Whitney Trust CO LLC | 2,273 | $1.03M | 0.05% | −80−3.4% | Reduced |
| Prospera Financial Services Inc | 2,285 | $1.04M | 0.02% | +52+2.3% | Added |
| Headinvest, LLC | 2,307 | $1.05M | 0.21% | −23−1.0% | Reduced |
| West Family Investments, Inc. | 2,328 | $1.06M | 0.25% | +5+0.2% | Added |
| We Are One Seven, LLC | 2,335 | $1.06M | 0.02% | +185+8.6% | Added |
| Alliance Wealth Advisors, LLC | 2,344 | $1.06M | 0.23% | −554−19.1% | Reduced |
| Generali Investments, Management Co LLC | 2,347 | $1.06M | 0.21% | +550+30.6% | Added |
| Brown Financial Advisors | 2,368 | $1.07M | 0.39% | +39+1.7% | Added |
| Prime Capital Investment Advisors, LLC | 2,409 | $1.09M | 0.01% | −349−12.7% | Reduced |
| Forum Financial Management, LP | 2,415 | $1.10M | 0.01% | −10.0% | Reduced |
| Simplicity Wealth,LLC | 2,418 | $1.10M | 0.07% | +405+20.1% | Added |
| Fred Alger Management, LLC | 2,433 | $1.10M | 0.00% | −603−19.9% | Reduced |
| Harel Insurance Investments & Financial Services Ltd. | 2,436 | $1.10M | 0.01% | +379+18.4% | Added |
| Malaga Cove Capital, LLC | 2,472 | $1.12M | 0.39% | −162−6.2% | Reduced |
| Moody National Bank Trust Division | 2,476 | $1.12M | 0.11% | −1,173−32.1% | Reduced |
| First American Trust, FSB | 2,477 | $1.12M | 0.08% | −484−16.3% | Reduced |
| Cigna Investments Inc | 2,482 | $1.13M | 0.16% | −39−1.5% | Reduced |
| Alps Advisors Inc | 2,498 | $1.13M | 0.01% | +99+4.1% | Added |
| Strid Group, LLC | 2,500 | $1.13M | 0.14% | 00.0% | Unchanged |
| Legacy Capital Group California, Inc. | 2,502 | $1.13M | 0.27% | +62+2.5% | Added |
| Ashton Thomas Private Wealth, LLC | 2,503 | $1.13M | 0.03% | +89+3.7% | Added |
| Westbourne Investments, Inc. | 2,506 | $1.14M | 0.53% | 00.0% | Unchanged |
| SWS Partners | 2,531 | $1.15M | 0.28% | +13+0.5% | Added |
| Regal Investment Advisors LLC | 2,540 | $1.15M | 0.07% | +97+4.0% | Added |
| Davis Investment Partners, LLC | 2,556 | $1.16M | 0.40% | +27+1.1% | Added |
| GraniteShares Advisors LLC | 2,564 | $1.16M | 0.71% | +42+1.7% | Added |
| MAI Capital Management | 2,564 | $1.16M | 0.01% | +718+38.9% | Added |
| Koa Wealth Management, LLC | 2,583 | $1.17M | 0.80% | −11−0.4% | Reduced |
| Qtron Investments LLC | 2,602 | $1.18M | 0.15% | +728+38.8% | Added |
| Westpac Banking Corp | 2,605 | $1.18M | 0.07% | +131+5.3% | Added |
| GTS Securities LLC | 2,622 | $1.19M | 0.04% | −3,112−54.3% | Reduced |
| Dakota Wealth Management | 2,623 | $1.19M | 0.02% | +43+1.7% | Added |
| Philip James Wealth Mangement, LLC | 2,628 | $1.19M | 0.14% | −1,431−35.3% | Reduced |
| Adviser Investments LLC | 2,637 | $1.20M | 0.01% | +747+39.5% | Added |
| Connecticut Wealth Management, LLC | 2,648 | $1.20M | 0.05% | 00.0% | Unchanged |
| Persistent Asset Partners Ltd | 2,666 | $1.21M | 0.58% | +2,666 | New |
| AE Wealth Management LLC | 2,730 | $1.24M | 0.01% | +958+54.1% | Added |
| Park Circle Co | 2,764 | $1.25M | 1.13% | 00.0% | Unchanged |
| Avestar Capital, LLC | 2,795 | $1.27M | 0.09% | −1,077−27.8% | Reduced |
| Crossmark Global Holdings, Inc. | 2,797 | $1.27M | 0.02% | −3,346−54.5% | Reduced |
| Cravens & Co Advisors, LLC | 2,797 | $1.27M | 0.83% | −480−14.6% | Reduced |
| Sowell Financial Services LLC | 2,814 | $1.28M | 0.05% | −1,198−29.9% | Reduced |
| Trust Asset Management LLC | 2,856 | $1.29M | 0.09% | −106−3.6% | Reduced |
| 111 Capital | 2,892 | $1.31M | 0.29% | −1,471−33.7% | Reduced |
| Pinebridge Investments LLC | 2,901 | $1.32M | 0.01% | +2,901 | New |
| Ashton Thomas Securities, LLC | 2,902 | $1.32M | 0.25% | −79−2.7% | Reduced |
| Bluebird Wealth Management LLC | 2,906 | $1.32M | 1.23% | +2,906 | New |
| Employees Retirement System of Texas | 2,918 | $1.32M | 0.01% | +2,918 | New |
| Lifeworks Advisors, LLC | 2,923 | $1.33M | 0.17% | +9+0.3% | Added |
| Centaurus Financial, Inc. | 2,936 | $1.33M | 0.06% | −91−3.0% | Reduced |
| Oak Ridge Investments LLC | 2,940 | $1.33M | 0.08% | +1,126+62.1% | Added |
| Capital Investment Advisory Services, LLC | 2,962 | $1.34M | 0.09% | −186−5.9% | Reduced |
| Legacy Financial Advisors, Inc. | 2,975 | $1.35M | 0.19% | +49+1.7% | Added |
| Hamrick Investment Counsel, llc | 2,983 | $1.35M | 1.01% | +2,983 | New |
| ZWJ Investment Counsel Inc | 2,987 | $1.35M | 0.05% | −804−21.2% | Reduced |