Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Blackhawk Capital Partners LLC. | 541 | $245.3K | 0.09% | −6−1.1% | Reduced |
| Beacon Financial Advisory LLC | 542 | $245.7K | 0.06% | +542 | New |
| Cladis Investment Advisory, LLC | 542 | $245.7K | 0.13% | +542 | New |
| SG Trading Solutions, LLC | 544 | $247.0K | 0.06% | +544 | New |
| Confluence Wealth Services, Inc. | 545 | $247.1K | 0.01% | +21+4.0% | Added |
| Fort Point Capital Partners LLC | 566 | $248.4K | 0.03% | −21−3.6% | Reduced |
| Custom Index Systems, LLC | 550 | $249.3K | 0.11% | 00.0% | Unchanged |
| KC Investment Advisors, LLC | 552 | $250.3K | 0.06% | −78−12.4% | Reduced |
| Hanson & Doremus Investment Management | 554 | $251.0K | 0.03% | +20+3.7% | Added |
| Nvest Financial, LLC | 554 | $251.2K | 0.10% | +5+0.9% | Added |
| Monetary Management Group Inc | 555 | $251.6K | 0.06% | 00.0% | Unchanged |
| Berman McAleer LLC | 557 | $252.5K | 0.03% | −40−6.7% | Reduced |
| Quent Capital, LLC | 557 | $252.5K | 0.02% | +56+11.2% | Added |
| Empower Advisory Group, LLC | 558 | $253.0K | 0.00% | −29−4.9% | Reduced |
| Catalyst Funds Management Pty Ltd | 560 | $253.9K | 0.06% | +560 | New |
| Opal Wealth Advisors, LLC | 561 | $254.3K | 0.07% | +561 | New |
| Axxcess Wealth Management, LLC | 565 | $256.1K | 0.00% | +565 | New |
| Asset Allocation & Management Company, LLC | 567 | $257.0K | 0.10% | 00.0% | Unchanged |
| Regent Peak Wealth Advisors LLC | 567 | $257.1K | 0.05% | +31+5.8% | Added |
| Elyxium Wealth, LLC | 568 | $257.4K | 0.07% | +46+8.8% | Added |
| Agf Management Ltd | 568 | $257.5K | 0.00% | −7,167−92.7% | Reduced |
| McAdam, LLC | 569 | $258.0K | 0.01% | −171−23.1% | Reduced |
| Anchyra Partners LLC | 569 | $258.0K | 0.08% | +569 | New |
| Whittier Trust Co of Nevada Inc | 553 | $259.0K | 0.01% | −104−15.8% | Reduced |
| Kingsview Wealth Management, LLC | 574 | $260.2K | 0.00% | +13+2.3% | Added |
| Meyer Handelman Co | 575 | $260.7K | 0.01% | +575 | New |
| 180 Wealth Advisors, LLC | 575 | $260.7K | 0.03% | +575 | New |
| Relyea Zuckerberg Hanson LLC | 576 | $261.1K | 0.03% | +22+4.0% | Added |
| Cambient Family Office, LLC | 582 | $263.8K | 0.04% | +582 | New |
| Capital Asset Advisory Services LLC | 565 | $264.6K | 0.01% | +565 | New |
| MBL Wealth, LLC | 584 | $264.9K | 0.02% | +584 | New |
| Kelly Lawrence W & Associates Inc | 585 | $265.2K | 0.06% | 00.0% | Unchanged |
| Signet Private Wealth LLC | 589 | $267.0K | 0.26% | +589 | New |
| Cullen/Frost Bankers, Inc. | 590 | $267.5K | 0.00% | +85+16.8% | Added |
| Icapital Wealth LLC | 591 | $268.0K | 0.13% | 00.0% | Unchanged |
| Aprio Wealth Management, LLC | 592 | $268.4K | 0.02% | +592 | New |
| TBH Global Asset Management, LLC | 592 | $268.5K | 0.05% | +592 | New |
| BCJ Capital Management, LLC | 593 | $268.8K | 0.02% | +37+6.7% | Added |
| Cary Street Partner Investment Advisory LLC | 595 | $269.7K | 0.07% | +203+51.8% | Added |
| Midwest Trust Co | 596 | $270.2K | 0.00% | −24−3.9% | Reduced |
| Coastline Trust Co | 597 | $270.7K | 0.03% | 00.0% | Unchanged |
| Strategic Blueprint, LLC | 600 | $272.0K | 0.02% | −1,164−66.0% | Reduced |
| Bartlett & Co. Wealth Management LLC | 601 | $272.5K | 0.00% | +1+0.2% | Added |
| Costello Asset Management, INC | 601 | $272.5K | 0.09% | +12+2.0% | Added |
| Centurion Wealth Management LLC | 603 | $273.4K | 0.06% | +18+3.1% | Added |
| Aries Wealth Management | 605 | $274.3K | 0.06% | 00.0% | Unchanged |
| Kraematon Investment Advisors, Inc | 608 | $275.5K | 0.22% | −140−18.7% | Reduced |
| Tannin Capital LLC | 609 | $276.1K | 0.25% | +609 | New |
| Keudell/Morrison Wealth Management | 612 | $277.5K | 0.06% | +612 | New |
| KPP Advisory Services LLC | 613 | $277.9K | 0.04% | −13−2.1% | Reduced |
| First American Bank | 614 | $278.4K | 0.02% | 00.0% | Unchanged |
| Nicolet Bankshares Inc | 617 | $279.7K | 0.04% | 00.0% | Unchanged |
| Interchange Capital Partners, LLC | 620 | $281.1K | 0.05% | −164−20.9% | Reduced |
| Fox Hill Wealth Management | 625 | $283.4K | 0.13% | −24−3.7% | Reduced |
| Park Place Capital Corp | 625 | $283.4K | 0.06% | +70+12.6% | Added |
| Meeder Asset Management Inc | 625 | $283.4K | 0.02% | +569+1,016.1% | Added |
| Green Alpha Advisors, LLC | 625 | $283.4K | 0.26% | +625 | New |
| Financiere des Professionnels - Fonds d,investissement inc. | 625 | $283.4K | 0.02% | +625 | New |
| Fairfield, Bush & Co. | 626 | $283.8K | 0.15% | −45−6.7% | Reduced |
| Urban Wealth Management, LLC | 626 | $283.8K | 0.26% | +626 | New |
| Western Wealth Management, LLC | 628 | $284.7K | 0.01% | +52+9.0% | Added |
| Cim, LLC | 629 | $285.2K | 0.04% | −2−0.3% | Reduced |
| Bryn Mawr Trust Co | 629 | $285.2K | 0.01% | 00.0% | Unchanged |
| Essex Savings Bank | 634 | $287.4K | 0.06% | −78−11.0% | Reduced |
| Spectrum Asset Management, Inc. (NB/CA) | 634 | $287.4K | 0.10% | +634 | New |
| Grimes & Company, Inc. | 636 | $288.5K | 0.01% | +15+2.4% | Added |
| Sentry Investment Management LLC | 640 | $290.0K | 0.19% | 00.0% | Unchanged |
| One Capital Management, LLC | 641 | $290.6K | 0.01% | −15−2.3% | Reduced |
| Clarity Financial LLC | 645 | $292.4K | 0.03% | 00.0% | Unchanged |
| Calamos Wealth Management LLC | 648 | $293.8K | 0.01% | +648 | New |
| Sittner & Nelson, LLC | 615 | $293.9K | 0.10% | 00.0% | Unchanged |
| Capital Performance Advisors LLP | 650 | $294.6K | 0.02% | +21+3.3% | Added |
| Financial Engines Advisors L.L.C. | 653 | $296.0K | 0.00% | +25+4.0% | Added |
| Kestra Investment Management, LLC | 658 | $298.3K | 0.01% | −87−11.7% | Reduced |
| Zullo Investment Group, Inc. | 659 | $298.8K | 0.11% | −20−2.9% | Reduced |
| Koss-Olinger Consulting, LLC | 659 | $299.0K | 0.02% | −298−31.1% | Reduced |
| Diversified Trust Co | 661 | $299.7K | 0.01% | +50+8.2% | Added |
| Quest Partners LLC | 661 | $299.7K | 0.02% | −355−34.9% | Reduced |
| Abundance Wealth Counselors | 663 | $300.6K | 0.05% | +1+0.2% | Added |
| Cromwell Holdings LLC | 663 | $300.6K | 0.16% | 00.0% | Unchanged |
| ICW Investment Advisors LLC | 664 | $301.0K | 0.11% | +32+5.1% | Added |
| Mason & Associates Inc | 665 | $301.5K | 0.06% | +10+1.5% | Added |
| May Hill Capital, LLC | 666 | $301.9K | 0.08% | +26+4.1% | Added |
| TRUE Private Wealth Advisors | 676 | $306.3K | 0.03% | −164−19.5% | Reduced |
| Center For Asset Management LLC | 677 | $306.9K | 0.16% | +677 | New |
| Sivia Capital Partners, LLC | 678 | $307.4K | 0.06% | −2−0.3% | Reduced |
| Alvarez & Marsal Private Wealth Partners, LLC | 678 | $307.4K | 0.06% | +678 | New |
| William Mack & Associates, Inc. | 682 | $309.2K | 0.15% | 00.0% | Unchanged |
| EFG International AG | 687 | $311.5K | 0.01% | +687 | New |
| Stock Yards Bank & Trust Co | 691 | $313.3K | 0.01% | −98−12.4% | Reduced |
| Ignite Planners, LLC | 667 | $313.4K | 0.05% | +667 | New |
| Versant Capital Management, Inc | 696 | $315.5K | 0.04% | +478+219.3% | Added |
| Daymark Wealth Partners, LLC | 697 | $316.0K | 0.01% | −2−0.3% | Reduced |
| Dark Forest Capital Management LP | 706 | $320.1K | 0.01% | −1,304−64.9% | Reduced |
| Alpha Zero LLC | 708 | $321.0K | 0.18% | −27−3.7% | Reduced |
| Quantbot Technologies LP | 709 | $321.4K | 0.01% | −3,018−81.0% | Reduced |
| Nautilus Advisors LLC | 710 | $321.9K | 0.21% | +50+7.6% | Added |
| UMA Financial Services, Inc. | 712 | $322.8K | 0.04% | +14+2.0% | Added |
| Eagle Wealth Advisors LLC | 716 | $324.6K | 0.28% | +716 | New |
| Wedgewood Investors Inc | 720 | $326.4K | 0.37% | +720 | New |