Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Kemnay Advisory Services Inc. | 101 | $45.8K | 0.01% | +101 | New |
| Geneos Wealth Management Inc. | 102 | $46.2K | 0.00% | −15−12.8% | Reduced |
| Lodestone Wealth Management LLC | 108 | $49.0K | 0.02% | +108 | New |
| Atlas Capital Advisors LLC | 110 | $49.9K | 0.01% | +110 | New |
| Strive Financial Group ,LLC | 113 | $51.2K | 0.03% | +113 | New |
| Oakworth Capital, Inc. | 114 | $51.7K | 0.00% | −108−48.6% | Reduced |
| JFS Wealth Advisors, LLC | 114 | $51.7K | 0.00% | +25+28.1% | Added |
| Capital Analysts, LLC | 116 | $52.0K | 0.00% | 00.0% | Unchanged |
| Cape Investment Advisory, Inc. | 115 | $52.1K | 0.02% | +55+91.7% | Added |
| Triumph Capital Management | 116 | $52.6K | 0.01% | +116 | New |
| MTM Investment Management, LLC | 117 | $53.0K | 0.02% | 00.0% | Unchanged |
| Kilter Group LLC | 118 | $53.5K | 0.02% | +9+8.3% | Added |
| Salomon & Ludwin, LLC | 121 | $54.3K | 0.00% | −12−9.0% | Reduced |
| Raleigh Capital Management Inc. | 120 | $54.4K | 0.02% | −6−4.8% | Reduced |
| Smallwood Wealth Investment Management, LLC | 121 | $54.9K | 0.03% | 00.0% | Unchanged |
| Gables Capital Management Inc. | 121 | $54.9K | 0.02% | 00.0% | Unchanged |
| Core Alternative Capital | 123 | $55.8K | 0.02% | −8−6.1% | Reduced |
| Financial Avengers, Inc. | 125 | $56.7K | 0.02% | 00.0% | Unchanged |
| Atlantic Edge Private Wealth Management, LLC | 125 | $56.7K | 0.01% | 00.0% | Unchanged |
| GHP Investment Advisors, Inc. | 125 | $56.8K | 0.00% | +20+19.0% | Added |
| Antipodes Partners Ltd | 127 | $57.6K | 0.00% | +127 | New |
| Cornerstone Planning Group LLC | 124 | $59.3K | 0.01% | +7+6.0% | Added |
| MidFirst Bank | 131 | $59.4K | 0.00% | +131 | New |
| Bell Investment Advisors, Inc | 132 | $59.8K | 0.01% | +27+25.7% | Added |
| Itau Unibanco Holding S.A. | 138 | $62.6K | 0.00% | +47+51.6% | Added |
| GW&K Investment Management, LLC | 151 | $68.0K | 0.00% | +8+5.6% | Added |
| Chelsea Counsel Co | 150 | $68.0K | 0.03% | 00.0% | Unchanged |
| PFS Partners, LLC | 158 | $71.6K | 0.03% | 00.0% | Unchanged |
| State of Wyoming | 159 | $72.1K | 0.01% | −157−49.7% | Reduced |
| Boreal Capital Management LLC | 159 | $72.1K | 0.05% | 00.0% | Unchanged |
| City State Bank | 160 | $72.5K | 0.02% | 00.0% | Unchanged |
| St Germain D J Co Inc | 161 | $73.0K | 0.00% | +16+11.0% | Added |
| Atlantic Trust, LLC | 161 | $73.0K | 0.01% | +29+22.0% | Added |
| Truvestments Capital LLC | 164 | $74.4K | 0.01% | −5−3.0% | Reduced |
| Ameriflex Group, Inc. | 166 | $75.3K | 0.04% | −26−13.5% | Reduced |
| Steigerwald, Gordon & Koch Inc. | 167 | $75.7K | 0.01% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 170 | $77.1K | 0.00% | +4+2.4% | Added |
| Colonial Trust Advisors | 173 | $78.4K | 0.01% | −50−22.4% | Reduced |
| Plante Moran Financial Advisors, LLC | 174 | $78.9K | 0.00% | −45−20.5% | Reduced |
| Greenline Wealth Management LLC | 176 | $79.7K | 0.08% | +176 | New |
| 1620 Investment Advisors, Inc. | 178 | $80.8K | 0.05% | 00.0% | Unchanged |
| Westside Investment Management, Inc. | 179 | $80.9K | 0.01% | +3+1.7% | Added |
| REAP Financial Group, LLC | 182 | $82.5K | 0.02% | +29+19.0% | Added |
| Cornerstone Financial Management LLC | 182 | $82.5K | 0.08% | +182 | New |
| Valley National Advisers Inc | 185 | $83.0K | 0.01% | 00.0% | Unchanged |
| Rosenberg Matthew Hamilton | 184 | $83.4K | 0.02% | +11+6.4% | Added |
| MV Capital Management, Inc. | 189 | $85.7K | 0.01% | +3+1.6% | Added |
| Edmond de Rothschild Holding S.A. | 191 | $86.6K | 0.00% | 00.0% | Unchanged |
| ORG Partners LLC | 193 | $87.5K | 0.02% | −53−21.5% | Reduced |
| Vestor Capital, LLC | 146 | $89.0K | 0.01% | −200−57.8% | Reduced |
| Moisand Fitzgerald Tamayo, LLC | 200 | $90.7K | 0.01% | 00.0% | Unchanged |
| Crews Bank & Trust | 212 | $96.1K | 0.01% | 00.0% | Unchanged |
| Toth Financial Advisory Corp | 230 | $104.3K | 0.01% | 00.0% | Unchanged |
| Trust Co of Toledo NA | 244 | $110.6K | 0.01% | 00.0% | Unchanged |
| WPG Advisers, LLC | 245 | $111.1K | 0.08% | +9+3.8% | Added |
| Trust Co of Vermont | 245 | $111.1K | 0.00% | +14+6.1% | Added |
| NBC Securities, Inc. | 246 | $111.5K | 0.01% | +58+30.9% | Added |
| Golden State Wealth Management, LLC | 250 | $113.3K | 0.01% | −15−5.7% | Reduced |
| QVR LLC | 253 | $114.7K | 0.08% | +253 | New |
| Acumen Wealth Advisors, LLC | 253 | $114.7K | 0.03% | +253 | New |
| MCF Advisors LLC | 254 | $115.2K | 0.01% | +71+38.8% | Added |
| Sankala Group LLC | 233 | $115.8K | 0.09% | +233 | New |
| Rossby Financial, LCC | 256 | $116.1K | 0.04% | −7−2.7% | Reduced |
| Kempen Capital Management N.V. | 257 | $116.5K | 0.00% | +16+6.6% | Added |
| Root Financial Partners, LLC | 269 | $122.0K | 0.01% | +46+20.6% | Added |
| PEAK6 LLC | 272 | $123.3K | 0.00% | −24,144−98.9% | Reduced |
| Hilltop National Bank | 272 | $123.3K | 0.03% | 00.0% | Unchanged |
| Roble, Belko & Company, Inc | 279 | $126.0K | 0.02% | 00.0% | Unchanged |
| Garton & Associates Financial Advisors LLC | 278 | $126.0K | 0.07% | +278 | New |
| Ritter Daniher Financial Advisory LLC | 282 | $127.8K | 0.02% | 00.0% | Unchanged |
| Reflection Asset Management | 288 | $130.6K | 0.09% | +288 | New |
| Tripletail Wealth Management, LLC | 290 | $131.5K | 0.17% | −20−6.5% | Reduced |
| Key Financial Inc | 290 | $131.5K | 0.02% | 00.0% | Unchanged |
| Asset Dedication, LLC | 294 | $133.3K | 0.01% | 00.0% | Unchanged |
| GPS Wealth Strategies Group, LLC | 297 | $134.6K | 0.11% | −599−66.9% | Reduced |
| McMillan Office, Inc. | 300 | $136.0K | 0.02% | +300 | New |
| TFC Financial Management | 307 | $139.2K | 0.02% | −1−0.3% | Reduced |
| Eastern Bank | 322 | $146.0K | 0.00% | −316−49.5% | Reduced |
| Clean Yield Group | 322 | $146.0K | 0.04% | 00.0% | Unchanged |
| Addison Advisors LLC | 326 | $147.8K | 0.03% | −6−1.8% | Reduced |
| Paradigm Asset Management Co LLC | 350 | $158.7K | 0.04% | 00.0% | Unchanged |
| Bard Associates Inc | 350 | $158.7K | 0.04% | +350 | New |
| DV Equities, LLC | 358 | $162.3K | 0.03% | +358 | New |
| Wealth Enhancement Trust Services, Inc. | 360 | $163.2K | 0.02% | +360 | New |
| Keating Financial Advisory Services, Inc. | 367 | $166.4K | 0.02% | +367 | New |
| Johnson Financial Group, Inc. | 367 | $166.4K | 0.01% | −281−43.4% | Reduced |
| LRI Investments, LLC | 374 | $169.4K | 0.01% | +5+1.4% | Added |
| Goodman Advisory Group, LLC | 379 | $171.8K | 0.04% | 00.0% | Unchanged |
| Rothschild Investment LLC | 387 | $175.4K | 0.01% | +41+11.8% | Added |
| CVA Family Office, LLC | 393 | $178.2K | 0.02% | +5+1.3% | Added |
| Deseret Mutual Benefit Administrators | 396 | $179.5K | 0.08% | +18+4.8% | Added |
| Private Wealth Asset Management, LLC | 402 | $182.3K | 0.02% | 00.0% | Unchanged |
| Manchester Capital Management LLC | 405 | $183.6K | 0.02% | +141+53.4% | Added |
| International Assets Investment Management, LLC | 410 | $185.9K | 0.01% | −88−17.7% | Reduced |
| Global Trust Asset Management, LLC | 430 | $194.9K | 0.08% | −156−26.6% | Reduced |
| Blalock Williams, LLC | 444 | $201.5K | 0.16% | +444 | New |
| Fox Run Management, L.L.C. | 449 | $203.6K | 0.03% | −167−27.1% | Reduced |
| Cornerstone Planning, LLC | 450 | $204.0K | 0.05% | +450 | New |
| Paragon Private Wealth Management, LLC | 450 | $204.0K | 0.06% | +450 | New |
| PFW Advisors LLC | 450 | $204.0K | 0.06% | +450 | New |