Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JustInvest LLC | 39,165 | $17.8M | 0.17% | +2,165+5.9% | Added |
| Police & Firemen's Retirement System of New Jersey | 39,473 | $17.9M | 0.15% | −1,903−4.6% | Reduced |
| William Blair Investment Management, LLC | 39,735 | $18.0M | 0.05% | +39,139+6,566.9% | Added |
| Segall Bryant & Hamill, LLC | 39,819 | $18.1M | 0.24% | −1,152−2.8% | Reduced |
| Osmosis Investment Management UK Ltd | 40,294 | $18.3M | 0.46% | +40,294 | New |
| Teachers Retirement System of the State of Kentucky | 40,323 | $18.3M | 0.14% | −2,258−5.3% | Reduced |
| Varma Mutual Pension Insurance Co | 40,626 | $18.4M | 0.11% | +5,700+16.3% | Added |
| Utah Retirement Systems | 42,490 | $19.3M | 0.18% | −90.0% | Reduced |
| Wealthfront Advisers LLC | 43,169 | $19.6M | 0.04% | +5,796+15.5% | Added |
| Martingale Asset Management L P | 43,221 | $19.6M | 0.50% | +6,699+18.3% | Added |
| Citizens Financial Group Inc | 43,403 | $19.7M | 0.26% | +522+1.2% | Added |
| Gradient Investments LLC | 43,595 | $19.8M | 0.31% | +2,618+6.4% | Added |
| Advisor Group Holdings, Inc. | 43,752 | $19.8M | 0.03% | −40,498−48.1% | Reduced |
| Calamos Advisors LLC | 43,969 | $19.9M | 0.08% | −1,784−3.9% | Reduced |
| W.G. Shaheen & Associates DBA Whitney & Co | 44,164 | $20.0M | 1.59% | +608+1.4% | Added |
| Macquarie Group Ltd | 44,736 | $20.3M | 0.09% | −178,820−80.0% | Reduced |
| USS Investment Management Ltd | 45,393 | $20.6M | 0.10% | +1,294+2.9% | Added |
| British Columbia Investment Management Corp | 45,496 | $20.6M | 0.11% | −86,351−65.5% | Reduced |
| Pathstone Holdings, LLC | 45,604 | $20.7M | 0.08% | +7,725+20.4% | Added |
| Trexquant Investment LP | 46,053 | $20.9M | 0.19% | +40,637+750.3% | Added |
| C WorldWide Group Holding A/S | 46,057 | $20.9M | 0.36% | 00.0% | Unchanged |
| Oddo BHF Asset Management SAS | 46,633 | $21.1M | 0.79% | +13,355+40.1% | Added |
| Illinois Municipal Retirement Fund | 46,786 | $21.2M | 0.27% | −6,015−11.4% | Reduced |
| Credit Agricole S A | 46,894 | $21.3M | 0.06% | −15,493−24.8% | Reduced |
| O'Shaughnessy Asset Management, LLC | 47,245 | $21.4M | 0.12% | +11,564+32.4% | Added |
| HighTower Advisors, LLC | 47,559 | $21.6M | 0.02% | +3,544+8.1% | Added |
| CIBC World Markets Corp | 47,710 | $21.6M | 0.11% | +47,710 | New |
| Rakuten Investment Management, Inc. | 47,185 | $21.7M | 0.07% | −195,277−80.5% | Reduced |
| Nomura Holdings Inc | 47,862 | $21.7M | 0.06% | −20,392−29.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 48,047 | $21.8M | 1.67% | +2,933+6.5% | Added |
| Zurich Insurance Group Ltd | 48,699 | $22.1M | 0.15% | +48,699 | New |
| Lido Advisors, LLC | 53,597 | $22.1M | 0.09% | −98−0.2% | Reduced |
| PensionDanmark Pensionsforsikringsaktieselskab | 49,381 | $22.4M | 0.20% | +49,381 | New |
| IFM Investors Pty Ltd | 49,780 | $22.6M | 0.19% | +296+0.6% | Added |
| Sanctuary Advisors, LLC | 49,804 | $22.6M | 0.12% | +3,551+7.7% | Added |
| Ci Investments Inc. | 49,891 | $22.6M | 0.10% | +38,900+353.9% | Added |
| Hallmark Capital Management Inc | 50,951 | $23.1M | 1.48% | +1,132+2.3% | Added |
| Hemenway Trust Co LLC | 51,017 | $23.1M | 1.77% | −4,108−7.5% | Reduced |
| Cullinan Associates Inc | 51,312 | $23.3M | 1.58% | −100−0.2% | Reduced |
| Smith Group Asset Management, LLC | 52,051 | $23.6M | 1.25% | +3,194+6.5% | Added |
| Forsta Ap-Fonden | 53,480 | $24.2M | 0.14% | −1,520−2.8% | Reduced |
| Harvest Fund Management Co., Ltd | 54,198 | $24.4M | 0.92% | +3,527+7.0% | Added |
| Reynders McVeigh Capital Management, LLC | 53,905 | $24.4M | 1.15% | −1,445−2.6% | Reduced |
| Retirement Systems of Alabama | 53,976 | $24.5M | 0.08% | −717−1.3% | Reduced |
| Commonwealth Equity Services, LLC | 54,143 | $24.5M | 0.03% | −4,142−7.1% | Reduced |
| Edgemoor Investment Advisors, Inc. | 54,839 | $24.9M | 1.93% | −355−0.6% | Reduced |
| Moody Lynn & Lieberson, LLC | 54,992 | $24.9M | 1.32% | −1,567−2.8% | Reduced |
| Amalgamated Bank | 55,120 | $25.0M | 0.18% | −1,394−2.5% | Reduced |
| Atwood & Palmer Inc | 55,392 | $25.1M | 1.43% | +95+0.2% | Added |
| Nisa Investment Advisors, LLC | 56,594 | $25.7M | 0.08% | +816+1.5% | Added |
| Zacks Investment Management | 56,626 | $25.7M | 0.20% | −1,400−2.4% | Reduced |
| Foster Dykema Cabot & Partners, LLC | 58,344 | $26.5M | 1.63% | −2,345−3.9% | Reduced |
| Ofi Invest Asset Management | 69,124 | $26.7M | 0.38% | +68,832+23,572.6% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 59,016 | $26.8M | 0.14% | −2,553−4.1% | Reduced |
| Motley Fool Wealth Management, LLC | 59,537 | $27.0M | 2.09% | −11,812−16.6% | Reduced |
| Natixis | 60,218 | $27.3M | 0.11% | +30,412+102.0% | Added |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 62,761 | $28.5M | 0.22% | +7,767+14.1% | Added |
| Trillium Asset Management, LLC | 62,693 | $28.6M | 0.87% | −5,692−8.3% | Reduced |
| Mackenzie Financial Corp | 63,299 | $28.7M | 0.03% | +8,956+16.5% | Added |
| Hardman Johnston Global Advisors LLC | 63,806 | $28.9M | 1.38% | −15,346−19.4% | Reduced |
| Davidson Investment Advisors | 64,227 | $29.1M | 1.21% | +1,806+2.9% | Added |
| GF Fund Management Co. Ltd. | 65,411 | $29.7M | 0.51% | +2,620+4.2% | Added |
| Xponance, Inc. | 65,773 | $29.8M | 0.22% | +3,282+5.3% | Added |
| Gateway Investment Advisers LLC | 66,108 | $30.0M | 0.28% | +182+0.3% | Added |
| Czech National Bank | 66,902 | $30.3M | 0.20% | +1,784+2.7% | Added |
| La Banque Postale Asset Management SA | 67,197 | $30.5M | 0.35% | +22,918+51.8% | Added |
| Comerica Bank | 67,686 | $30.7M | 0.12% | −339−0.5% | Reduced |
| Rafferty Asset Management, LLC | 68,082 | $30.9M | 0.11% | −13,046−16.1% | Reduced |
| Erste Asset Management GmbH | 67,363 | $31.0M | 0.26% | −154−0.2% | Reduced |
| State of Michigan Retirement System | 69,223 | $31.4M | 0.15% | −2,800−3.9% | Reduced |
| The PNC Financial Services Group, Inc. | 69,425 | $31.5M | 0.02% | −347−0.5% | Reduced |
| Nissay Asset Management Corp | 69,627 | $31.6M | 0.16% | +2,970+4.5% | Added |
| Janney Montgomery Scott LLC | 70,353 | $31.9M | 0.07% | −7,103−9.2% | Reduced |
| Daiwa Securities Group Inc. | 70,595 | $32.0M | 0.10% | +3,368+5.0% | Added |
| Arizona State Retirement System | 72,293 | $32.8M | 0.18% | −2,701−3.6% | Reduced |
| Swiss Life Asset Management Ltd | 73,018 | $33.1M | 0.17% | +9,073+14.2% | Added |
| MetLife Investment Management | 73,281 | $33.2M | 0.16% | −2,526−3.3% | Reduced |
| Beacon Investment Advisory Services, Inc. | 74,093 | $33.6M | 1.37% | −2,049−2.7% | Reduced |
| Cetera Investment Advisers | 75,013 | $34.0M | 0.04% | −2,701−3.5% | Reduced |
| Pacer Advisors, Inc. | 76,142 | $34.5M | 0.09% | +9,641+14.5% | Added |
| Thrivent Financial for Lutherans | 76,687 | $34.8M | 0.06% | −1,583−2.0% | Reduced |
| Iron Triangle Partners LP | 76,910 | $34.9M | 3.99% | +76,910 | New |
| Eurizon Capital SGR S.p.A. | 77,394 | $35.1M | 0.11% | +77,394 | New |
| Federated Hermes, Inc. | 77,661 | $35.2M | 0.06% | −108,908−58.4% | Reduced |
| STRS Ohio | 78,278 | $35.5M | 0.13% | −2,347−2.9% | Reduced |
| Tang Capital Management LLC | 80,000 | $36.3M | 1.79% | 00.0% | Unchanged |
| ING Groep NV | 81,129 | $36.8M | 0.22% | +69,140+576.7% | Added |
| State of Tennessee, Treasury Department | 80,373 | $37.8M | 0.12% | −6,388−7.4% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 81,246 | $38.1M | 0.05% | +7,777+10.6% | Added |
| Susquehanna International Group, LLP | 84,096 | $38.1M | 0.05% | +16,413+24.2% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 87,728 | $39.8M | 0.07% | +3,882+4.6% | Added |
| State of New Jersey Common Pension Fund D | 87,835 | $39.8M | 0.14% | −2,294−2.5% | Reduced |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 89,062 | $40.4M | 0.34% | −560−0.6% | Reduced |
| Resona Asset Management Co.,Ltd. | 89,399 | $40.6M | 0.20% | −2,699−2.9% | Reduced |
| Assetmark, Inc | 90,483 | $41.0M | 0.08% | +633+0.7% | Added |
| Toronto Dominion Bank | 91,288 | $41.4M | 0.07% | −13,590−13.0% | Reduced |
| Lansforsakringar Fondforvaltning AB (publ) | 91,826 | $41.6M | 0.21% | −54,737−37.3% | Reduced |
| Quantinno Capital Management LP | 92,284 | $41.8M | 0.08% | +36,643+65.9% | Added |
| KLP Kapitalforvaltning AS | 92,901 | $42.1M | 0.16% | +260+0.3% | Added |
| Banco Bilbao Vizcaya Argentaria, S.A. | 93,837 | $42.6M | 0.30% | −4,316−4.4% | Reduced |