Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| AG2R la Mondiale Gestion D'Actifs | 10,375 | $4.70M | 0.21% | +587+6.0% | Added |
| MUFG Securities EMEA plc | 10,401 | $4.72M | 0.05% | +5,494+112.0% | Added |
| Fideuram Asset Management (Ireland) dac | 9,876 | $4.72M | 0.38% | +9,876 | New |
| Morse Asset Management, Inc | 10,423 | $4.73M | 0.94% | +118+1.1% | Added |
| Kestra Private Wealth Services, LLC | 10,438 | $4.73M | 0.06% | +184+1.8% | Added |
| Joseph Group Capital Management | 10,489 | $4.76M | 1.25% | +121+1.2% | Added |
| Generali Investments CEE, investicni spolecnost, a.s. | 10,491 | $4.76M | 0.34% | 00.0% | Unchanged |
| BI Asset Management Fondsmaeglerselskab A/S | 10,526 | $4.77M | 0.04% | −76−0.7% | Reduced |
| Winton Group Ltd | 10,623 | $4.82M | 0.17% | +10,623 | New |
| Northwest Bancshares, Inc. | 10,636 | $4.82M | 0.93% | −1,502−12.4% | Reduced |
| Cornerstone Advisors, LLC | 10,700 | $4.85M | 0.16% | −25,400−70.4% | Reduced |
| Vinva Investment Management Ltd | 10,938 | $4.96M | 0.06% | +2,303+26.7% | Added |
| Banque Cantonale Vaudoise | 11,076 | $5.02M | 0.18% | +954+9.4% | Added |
| Benjamin Edwards Inc | 11,093 | $5.03M | 0.06% | +597+5.7% | Added |
| Northwest & Ethical Investments L.P. | 11,104 | $5.03M | 0.11% | −4,211−27.5% | Reduced |
| PKO Investment Management Joint-Stock Co | 11,200 | $5.08M | 0.41% | −300−2.6% | Reduced |
| Siemens Fonds Invest GmbH | 11,212 | $5.09M | 0.27% | +470+4.4% | Added |
| Jane Street Group, LLC | 11,246 | $5.10M | 0.01% | −237,021−95.5% | Reduced |
| Slow Capital, Inc. | 11,344 | $5.14M | 0.61% | +44+0.4% | Added |
| Horizon Investments, LLC | 11,375 | $5.16M | 0.07% | +2,181+23.7% | Added |
| Kayne Anderson Rudnick Investment Management LLC | 11,645 | $5.28M | 0.01% | +26+0.2% | Added |
| Lombard Odier Asset Management (Switzerland) SA | 11,692 | $5.30M | 0.23% | +11,692 | New |
| New Mexico Educational Retirement Board | 11,700 | $5.30M | 0.16% | +100+0.9% | Added |
| Diversify Wealth Management, LLC | 11,690 | $5.32M | 0.25% | −524−4.3% | Reduced |
| Laird Norton Trust Company, LLC | 11,757 | $5.33M | 0.11% | +11,757 | New |
| Traynor Capital Management, Inc. | 11,767 | $5.33M | 0.29% | −198−1.7% | Reduced |
| Covenant Asset Management, LLC | 11,889 | $5.39M | 1.04% | −215−1.8% | Reduced |
| Exchange Traded Concepts, LLC | 12,025 | $5.45M | 0.05% | +1,874+18.5% | Added |
| United Capital Financial Advisers, LLC | 12,077 | $5.48M | 0.03% | +565+4.9% | Added |
| Chicago Capital, LLC | 12,145 | $5.51M | 0.14% | −679−5.3% | Reduced |
| Brinker Capital Investments, LLC | 12,151 | $5.51M | 0.04% | +1,803+17.4% | Added |
| First Horizon Corp | 12,155 | $5.51M | 0.25% | −1,966−13.9% | Reduced |
| Greenwood Capital Associates LLC | 12,322 | $5.59M | 0.61% | −490−3.8% | Reduced |
| Andrew Hill Investment Advisors, Inc. | 12,408 | $5.63M | 4.28% | +8,699+234.5% | Added |
| Kidder Stephen W | 12,459 | $5.65M | 1.59% | +161+1.3% | Added |
| New Age Alpha Advisors, LLC | 12,622 | $5.72M | 0.25% | −1,317−9.4% | Reduced |
| Compagnie Lombard Odier SCmA | 12,665 | $5.74M | 0.06% | +100+0.8% | Added |
| Metis Global Partners, LLC | 12,666 | $5.74M | 0.14% | −758−5.6% | Reduced |
| Capitolis Liquid Global Markets LLC | 12,815 | $5.81M | 0.03% | +12,815 | New |
| Maryland State Retirement & Pension System | 12,846 | $5.82M | 0.12% | 00.0% | Unchanged |
| Gulf International Bank (UK) Ltd | 12,916 | $5.86M | 0.19% | +37+0.3% | Added |
| Fisher Funds Management LTD | 12,898 | $5.86M | 0.15% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 13,016 | $5.90M | 0.02% | +2,199+20.3% | Added |
| Princeton Global Asset Management LLC | 13,159 | $5.97M | 0.97% | −200−1.5% | Reduced |
| Walleye Trading LLC | 13,339 | $6.05M | 0.10% | +13,339 | New |
| Beacon Pointe Advisors, LLC | 13,502 | $6.12M | 0.04% | +218+1.6% | Added |
| Tower Research Capital LLC (TRC) | 13,579 | $6.16M | 0.15% | −443−3.2% | Reduced |
| Sequoia Financial Advisors, LLC | 13,596 | $6.16M | 0.03% | −384−2.7% | Reduced |
| Baader Bank INC | 13,604 | $6.16M | 0.51% | +13,604 | New |
| Vident Advisory, LLC | 13,685 | $6.20M | 0.06% | +463+3.5% | Added |
| ADAR1 Capital Management, LLC | 13,716 | $6.22M | 0.47% | +6,716+95.9% | Added |
| Zions Bancorporation, National Association | 13,758 | $6.24M | 0.29% | +4,120+42.7% | Added |
| Sivik Global Healthcare LLC | 13,770 | $6.24M | 3.05% | −230−1.6% | Reduced |
| Captrust Financial Advisors | 13,804 | $6.26M | 0.01% | +1,730+14.3% | Added |
| Park Avenue Securities LLC | 13,807 | $6.26M | 0.05% | −1,236−8.2% | Reduced |
| Allworth Financial LP | 14,036 | $6.36M | 0.03% | +11,306+414.1% | Added |
| Knuff & Co LLC | 14,197 | $6.44M | 1.90% | +13+0.1% | Added |
| Hamilton Capital Partners Inc. | 14,220 | $6.45M | 0.24% | +1,891+15.3% | Added |
| Atlantic Union Bankshares Corp | 14,233 | $6.45M | 0.12% | −455−3.1% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 14,357 | $6.51M | 0.02% | +240+1.7% | Added |
| Kestra Advisory Services, LLC | 14,431 | $6.54M | 0.03% | +40+0.3% | Added |
| Callan Family Office, LLC | 14,440 | $6.55M | 0.14% | +3,235+28.9% | Added |
| Princeton Capital Management LLC | 14,509 | $6.58M | 1.70% | +71+0.5% | Added |
| Dai-Ichi Life Insurance Company, Ltd | 14,538 | $6.59M | 0.17% | +2,400+19.8% | Added |
| Hartford Investment Management Co | 14,662 | $6.65M | 0.20% | −360−2.4% | Reduced |
| M&T Bank Corp | 14,732 | $6.68M | 0.02% | +2,408+19.5% | Added |
| Empowered Funds, LLC | 14,806 | $6.71M | 0.11% | +1,223+9.0% | Added |
| Walleye Capital LLC | 14,974 | $6.79M | 0.04% | +12,512+508.2% | Added |
| Liontrust Investment Partners LLP | 15,046 | $6.82M | 0.10% | −15,254−50.3% | Reduced |
| NLB Skladi, upravljanje premozenja, d.o.o. | 15,151 | $6.87M | 0.31% | +15,151 | New |
| Ameritas Investment Partners, Inc. | 15,181 | $6.88M | 0.21% | +350+2.4% | Added |
| Puzo Michael J | 15,371 | $6.97M | 1.90% | −130−0.8% | Reduced |
| Torray LLC | 15,466 | $7.01M | 1.00% | −789−4.9% | Reduced |
| Omers Administration Corp | 15,479 | $7.02M | 0.05% | +1,725+12.5% | Added |
| Janney Capital Management LLC | 15,542 | $7.05M | 0.44% | −165−1.1% | Reduced |
| Baldwin Investment Management, LLC | 15,554 | $7.05M | 0.80% | −194−1.2% | Reduced |
| Bleakley Financial Group, LLC | 15,594 | $7.07M | 0.12% | +15,594 | New |
| Prevail Innovative Wealth Advisors, LLC | 15,613 | $7.08M | 1.27% | +413+2.7% | Added |
| Third View Private Wealth, LLC | 15,717 | $7.13M | 0.96% | +15,717 | New |
| Anderson Hoagland & Co | 15,734 | $7.13M | 0.61% | −33−0.2% | Reduced |
| Prudential PLC | 15,771 | $7.15M | 0.06% | −797−4.8% | Reduced |
| Ethic Inc. | 15,983 | $7.25M | 0.11% | +2,012+14.4% | Added |
| Silvercrest Asset Management Group LLC | 16,028 | $7.27M | 0.05% | −931−5.5% | Reduced |
| Boston Common Asset Management, LLC | 16,081 | $7.29M | 0.44% | −24,818−60.7% | Reduced |
| Blair William & Co | 16,090 | $7.29M | 0.02% | −1,900−10.6% | Reduced |
| Kentucky Retirement Systems | 16,147 | $7.32M | 0.20% | 00.0% | Unchanged |
| Leuthold Group, LLC | 16,407 | $7.44M | 0.80% | +3,564+27.8% | Added |
| Madison Asset Management, LLC | 16,435 | $7.45M | 0.09% | +234+1.4% | Added |
| Aptus Capital Advisors, LLC | 16,442 | $7.45M | 0.06% | +687+4.4% | Added |
| LMR Partners LLP | 16,468 | $7.47M | 0.07% | +367+2.3% | Added |
| Envestnet Portfolio Solutions, Inc. | 16,469 | $7.47M | 0.03% | −1,752−9.6% | Reduced |
| Trifecta Capital Advisors, LLC | 16,497 | $7.48M | 1.11% | +664+4.2% | Added |
| Fulcrum Capital LLC | 16,616 | $7.53M | 1.51% | +360+2.2% | Added |
| Oppenheimer Asset Management Inc. | 16,720 | $7.58M | 0.09% | −8,740−34.3% | Reduced |
| Toroso Investments, LLC | 16,838 | $7.63M | 0.03% | +2,206+15.1% | Added |
| Broderick Brian C | 17,202 | $7.80M | 1.47% | −49−0.3% | Reduced |
| GWM Advisors LLC | 17,335 | $7.86M | 0.03% | +5,617+47.9% | Added |
| Steward Partners Investment Advisory, LLC | 17,364 | $7.87M | 0.04% | −9,997−36.5% | Reduced |
| Jacobs Levy Equity Management, Inc | 17,416 | $7.90M | 0.03% | −7,533−30.2% | Reduced |
| Simplify Asset Management Inc. | 17,492 | $7.93M | 0.13% | +16,267+1,327.9% | Added |