Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Principal Securities, Inc. | 6,319 | $2.86M | 0.04% | −518−7.6% | Reduced |
| Resources Investment Advisors, LLC. | 6,392 | $2.90M | 0.03% | +4,898+327.8% | Added |
| South Dakota Investment Council | 6,400 | $2.90M | 0.06% | −480−7.0% | Reduced |
| Boomfish Wealth Group, LLC | 6,410 | $2.91M | 1.55% | −237−3.6% | Reduced |
| Camden Capital, LLC | 6,439 | $2.92M | 0.18% | +941+17.1% | Added |
| Canada Post Corp Registered Pension Plan | 6,474 | $2.94M | 0.11% | +2,420+59.7% | Added |
| Condor Capital Management | 6,487 | $2.94M | 0.24% | −20−0.3% | Reduced |
| Baird Financial Group, Inc. | 6,511 | $2.95M | 0.00% | −659−9.2% | Reduced |
| Atomi Financial Group, Inc. | 6,541 | $2.97M | 0.09% | +4,157+174.4% | Added |
| Vision Capital Management, Inc. | 6,595 | $2.99M | 0.36% | +29+0.4% | Added |
| Channel Wealth LLC | 6,606 | $2.99M | 0.76% | −3,953−37.4% | Reduced |
| Leavell Investment Management, Inc. | 6,645 | $3.01M | 0.13% | −340−4.9% | Reduced |
| Kinneret Advisory, LLC | 6,681 | $3.03M | 0.26% | −183−2.7% | Reduced |
| Thompson Siegel & Walmsley LLC | 6,698 | $3.04M | 0.05% | −105−1.5% | Reduced |
| Edgestream Partners, L.P. | 6,703 | $3.04M | 0.09% | −1,043−13.5% | Reduced |
| Kentucky Retirement Systems Insurance Trust Fund | 6,768 | $3.07M | 0.20% | 00.0% | Unchanged |
| Wahed Invest LLC | 6,771 | $3.07M | 0.40% | −29−0.4% | Reduced |
| MUFG Securities Americas Inc. | 6,835 | $3.10M | 0.19% | −79−1.1% | Reduced |
| RDA Financial Network | 6,839 | $3.10M | 0.75% | +130+1.9% | Added |
| North Star Asset Management Inc | 6,859 | $3.11M | 0.13% | −24−0.3% | Reduced |
| Securian Asset Management, Inc | 6,899 | $3.13M | 0.12% | −5,417−44.0% | Reduced |
| Diversify Advisory Services, LLC | 7,127 | $3.15M | 0.10% | −183−2.5% | Reduced |
| Associated Banc-Corp | 6,947 | $3.15M | 0.08% | −171−2.4% | Reduced |
| Delaney Dennis R | 6,969 | $3.16M | 1.59% | −79−1.1% | Reduced |
| Commerce Bank | 6,999 | $3.17M | 0.02% | +67+1.0% | Added |
| Glenview Trust Co | 7,005 | $3.18M | 0.05% | +24+0.3% | Added |
| RSM US Wealth Management LLC | 7,008 | $3.18M | 0.04% | +1,154+19.7% | Added |
| Elefante Mark B | 7,015 | $3.18M | 1.95% | +352+5.3% | Added |
| Dempze Nancy E | 7,058 | $3.20M | 1.67% | −194−2.7% | Reduced |
| CIBC Private Wealth Group, LLC | 7,087 | $3.21M | 0.01% | +289+4.3% | Added |
| BNP Paribas | 7,139 | $3.24M | 0.09% | +1,798+33.7% | Added |
| Hantz Financial Services, Inc. | 7,191 | $3.26M | 0.05% | +961+15.4% | Added |
| Freemont Management S.A. | 7,200 | $3.26M | 0.64% | +4,800+200.0% | Added |
| SummitTX Capital, L.P. | 7,231 | $3.28M | 0.10% | −724−9.1% | Reduced |
| Codex Capital Asset Management L.L.C. | 7,320 | $3.32M | 1.21% | +70+1.0% | Added |
| Stenger Family Office, LLC | 7,323 | $3.32M | 0.69% | −3,398−31.7% | Reduced |
| CWM, LLC | 7,343 | $3.33M | 0.01% | +1,401+23.6% | Added |
| Central Trust Co | 7,363 | $3.34M | 0.07% | −1,030−12.3% | Reduced |
| EagleClaw Capital Managment, LLC | 7,385 | $3.35M | 0.48% | 00.0% | Unchanged |
| Marex Group plc | 7,442 | $3.37M | 0.04% | −298−3.9% | Reduced |
| Graphene Investments SAS | 7,500 | $3.40M | 2.13% | −800−9.6% | Reduced |
| Cresset Asset Management, LLC | 7,555 | $3.43M | 0.01% | −37−0.5% | Reduced |
| Transamerica Financial Advisors, Inc. | 7,584 | $3.44M | 0.29% | −131−1.7% | Reduced |
| Bessemer Group Inc | 7,592 | $3.44M | 0.01% | −867−10.2% | Reduced |
| Johnson Investment Counsel Inc | 7,726 | $3.50M | 0.03% | −4−0.1% | Reduced |
| Brown Advisory Inc | 7,774 | $3.52M | 0.00% | −320−4.0% | Reduced |
| Vestmark Advisory Solutions, Inc. | 7,822 | $3.55M | 0.05% | −1,606−17.0% | Reduced |
| Baldwin Brothers Inc | 7,824 | $3.55M | 0.23% | −120−1.5% | Reduced |
| Notis-McConarty Edward | 7,854 | $3.56M | 1.65% | +50+0.6% | Added |
| J.P. Marvel Investment Advisors, LLC | 7,855 | $3.56M | 0.49% | 00.0% | Unchanged |
| Gabelli Funds LLC | 7,984 | $3.62M | 0.02% | −7,018−46.8% | Reduced |
| Jones Financial Companies LLLP | 7,995 | $3.62M | 0.00% | +871+12.2% | Added |
| Crestwood Advisors Group LLC | 8,003 | $3.63M | 0.06% | −1,148−12.5% | Reduced |
| Sectoral Asset Management Inc | 8,005 | $3.63M | 2.91% | +290+3.8% | Added |
| Commerzbank Aktiengesellschaft | 8,091 | $3.67M | 0.07% | −484−5.6% | Reduced |
| SageGuard Financial Group, LLC | 8,103 | $3.67M | 0.58% | +8,103 | New |
| Northwestern Mutual Investment Management Company, LLC | 8,107 | $3.68M | 0.04% | −64−0.8% | Reduced |
| Sumitomo Life Insurance Co | 8,126 | $3.68M | 0.10% | +1,033+14.6% | Added |
| CIBC World Markets Inc. | 8,133 | $3.69M | 0.01% | −103−1.3% | Reduced |
| Ashford Capital Management Inc | 8,245 | $3.74M | 0.42% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 8,300 | $3.76M | 0.00% | −7−0.1% | Reduced |
| NewEdge Wealth, LLC | 8,402 | $3.81M | 0.04% | +2,754+48.8% | Added |
| Linden Thomas Advisory Services, LLC | 8,405 | $3.81M | 0.39% | −14−0.2% | Reduced |
| Verition Fund Management LLC | 8,406 | $3.81M | 0.02% | −3,138−27.2% | Reduced |
| Private Advisor Group, LLC | 8,694 | $3.94M | 0.02% | +1,330+18.1% | Added |
| Empirical Finance, LLC | 8,711 | $3.95M | 0.19% | −782−8.2% | Reduced |
| Bensler, LLC | 8,746 | $3.96M | 0.40% | −90−1.0% | Reduced |
| Davidson Capital Management Inc. | 8,759 | $3.97M | 0.86% | −36−0.4% | Reduced |
| Strategic Advisors LLC | 8,775 | $3.98M | 0.62% | −79−0.9% | Reduced |
| North Dakota State Investment Board | 8,821 | $4.00M | 0.15% | +8,821 | New |
| Sepio Capital, LP | 8,865 | $4.02M | 0.22% | −198−2.2% | Reduced |
| Little House Capital LLC | 8,939 | $4.05M | 1.02% | −821−8.4% | Reduced |
| EP Wealth Advisors, LLC | 8,946 | $4.06M | 0.02% | +8,946 | New |
| Merit Financial Group, LLC | 8,967 | $4.07M | 0.03% | +2,880+47.3% | Added |
| Lighthouse Investment Partners, LLC | 9,000 | $4.08M | 0.14% | +6,500+260.0% | Added |
| E. Ohman J:or Asset Management AB | 9,023 | $4.09M | 0.10% | −1,497−14.2% | Reduced |
| Peloton Wealth Strategists | 9,040 | $4.10M | 1.59% | +1,165+14.8% | Added |
| Meiji Yasuda Asset Management Co Ltd. | 9,221 | $4.18M | 0.20% | −279−2.9% | Reduced |
| Howard Capital Management Inc. | 9,274 | $4.20M | 0.05% | +360+4.0% | Added |
| Tokio Marine Asset Management Co Ltd | 9,324 | $4.23M | 0.15% | +368+4.1% | Added |
| Privium Fund Management B.V. | 9,355 | $4.24M | 0.78% | +1,055+12.7% | Added |
| HB Wealth Management, LLC | 9,472 | $4.29M | 0.03% | +792+9.1% | Added |
| F/M Investments LLC | 9,484 | $4.30M | 0.16% | −280−2.9% | Reduced |
| Parsons Capital Management Inc | 9,491 | $4.30M | 0.24% | −395−4.0% | Reduced |
| Howe & Rusling Inc | 9,518 | $4.31M | 0.29% | +168+1.8% | Added |
| GAM Holding AG | 9,552 | $4.33M | 0.28% | −1,463−13.3% | Reduced |
| Level Four Advisory Services, LLC | 9,553 | $4.33M | 0.14% | +1,967+25.9% | Added |
| Cumberland Partners Ltd | 9,607 | $4.36M | 0.27% | −137−1.4% | Reduced |
| Tema ETFs LLC | 9,612 | $4.36M | 0.34% | −39−0.4% | Reduced |
| Concurrent Investment Advisors, LLC | 9,734 | $4.41M | 0.05% | +6,895+242.9% | Added |
| FIL Ltd | 9,803 | $4.44M | 0.00% | +1,097+12.6% | Added |
| Miracle Mile Advisors, LLC | 9,834 | $4.46M | 0.06% | +759+8.4% | Added |
| Campbell & CO Investment Adviser LLC | 9,858 | $4.47M | 0.21% | +7,835+387.3% | Added |
| Journey Retirement Planning & Investment Management LLC | 9,892 | $4.48M | 0.92% | +9,892 | New |
| Fayez Sarofim & Co | 10,000 | $4.53M | 0.01% | −58−0.6% | Reduced |
| Diadema Partners LP | 10,000 | $4.53M | 2.70% | +10,000 | New |
| DKRT Investments Corp. | 10,000 | $4.53M | 1.28% | +10,000 | New |
| Sigma Investment Counselors Inc | 10,021 | $4.54M | 0.23% | −118−1.2% | Reduced |
| Keybank National Association | 10,130 | $4.59M | 0.02% | +91+0.9% | Added |
| Mark Sheptoff Financial Planning, LLC | 10,246 | $4.65M | 2.21% | −525−4.9% | Reduced |