Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nations Financial Group Inc, | 4,288 | $1.94M | 0.10% | −20.0% | Reduced |
| Paradigm Financial Partners, LLC | 4,295 | $1.95M | 0.20% | −1,582−26.9% | Reduced |
| Skopos Labs, Inc. | 4,239 | $1.95M | 0.09% | +1,462+52.6% | Added |
| GKV Capital Management Co., Inc. | 4,305 | $1.95M | 0.73% | +100+2.4% | Added |
| Portside Wealth Group, LLC | 4,314 | $1.96M | 0.26% | +571+15.3% | Added |
| Signature Wealth Management Group | 4,324 | $1.96M | 0.80% | +213+5.2% | Added |
| Global Retirement Partners, LLC | 4,345 | $1.97M | 0.03% | +2,012+86.2% | Added |
| Harrell Investment Partners, LLC | 4,377 | $1.98M | 0.47% | +12+0.3% | Added |
| Ritholtz Wealth Management | 4,412 | $2.00M | 0.04% | +759+20.8% | Added |
| Farther Finance Advisors, LLC | 4,421 | $2.00M | 0.02% | +1,028+30.3% | Added |
| Mather Group, LLC. | 4,425 | $2.01M | 0.02% | +86+2.0% | Added |
| Decatur Capital Management, Inc. | 4,426 | $2.01M | 0.82% | −238−5.1% | Reduced |
| Private Harbour Investment Management & Counsel, LLC | 4,436 | $2.01M | 2.10% | −13−0.3% | Reduced |
| McGuire Investment Group, LLC | 4,453 | $2.02M | 0.22% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 4,518 | $2.05M | 0.01% | +1,399+44.9% | Added |
| LGT Group Foundation | 4,522 | $2.05M | 0.02% | −98−2.1% | Reduced |
| Strategic Wealth Partners, Ltd. | 4,560 | $2.07M | 0.14% | −483−9.6% | Reduced |
| Bangor Savings Bank | 4,576 | $2.07M | 0.17% | −323−6.6% | Reduced |
| Cambria Investment Management, L.P. | 4,585 | $2.08M | 0.12% | +404+9.7% | Added |
| Impax Asset Management Group plc | 4,622 | $2.10M | 0.01% | 00.0% | Unchanged |
| AlphaCentric Advisors LLC | 4,663 | $2.11M | 2.11% | +4,663 | New |
| Engineers Gate Manager LP | 4,664 | $2.11M | 0.03% | −10,179−68.6% | Reduced |
| Hedeker Wealth, LLC | 4,665 | $2.11M | 0.44% | −2,996−39.1% | Reduced |
| Oak Associates, Ltd | 4,677 | $2.12M | 0.13% | −94−2.0% | Reduced |
| Valeo Financial Advisors, LLC | 4,682 | $2.12M | 0.05% | −74−1.6% | Reduced |
| Torrey Growth & Income Advisors | 4,719 | $2.14M | 0.74% | −681−12.6% | Reduced |
| Integrated Wealth Concepts LLC | 4,721 | $2.14M | 0.03% | +147+3.2% | Added |
| Greenleaf Trust | 4,742 | $2.15M | 0.02% | +39+0.8% | Added |
| GLOBALT Investments LLC | 4,743 | $2.15M | 0.08% | −29−0.6% | Reduced |
| Cito Capital Group, LLC | 4,756 | $2.16M | 0.63% | +2,700+131.3% | Added |
| Trustmark National Bank Trust Department | 4,763 | $2.16M | 0.14% | −68−1.4% | Reduced |
| De Burlo Group Inc | 4,785 | $2.17M | 0.26% | −240−4.8% | Reduced |
| Oarsman Capital, Inc. | 4,790 | $2.17M | 0.28% | +74+1.6% | Added |
| Evergreen Capital Management LLC | 4,801 | $2.18M | 0.05% | +2,304+92.3% | Added |
| Future Fund LLC | 4,803 | $2.18M | 0.77% | −384−7.4% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 4,812 | $2.18M | 0.08% | −1,192−19.9% | Reduced |
| Fiduciary Alliance LLC | 4,828 | $2.19M | 0.14% | +4,828 | New |
| Quadrant Capital Group LLC | 4,850 | $2.20M | 0.07% | −825−14.5% | Reduced |
| AlphaCore Capital LLC | 4,880 | $2.21M | 0.05% | −375−7.1% | Reduced |
| Aaron Wealth Advisors | 4,925 | $2.23M | 0.12% | +1,003+25.6% | Added |
| Knollwood Investment Advisory, LLC | 4,988 | $2.26M | 0.21% | 00.0% | Unchanged |
| Meiji Yasuda Life Insurance Co | 5,005 | $2.27M | 0.07% | −33−0.7% | Reduced |
| Advisory Services Network, LLC | 5,009 | $2.27M | 0.03% | +162+3.3% | Added |
| Leonteq Securities AG | 5,026 | $2.28M | 0.12% | −2,002−28.5% | Reduced |
| Central Pacific Bank - Trust Division | 5,026 | $2.28M | 0.28% | +24+0.5% | Added |
| TFR Capital, LLC. | 5,026 | $2.28M | 0.75% | +91+1.8% | Added |
| Legacy Capital Wealth Management, LLC | 5,043 | $2.29M | 1.38% | +5,043 | New |
| Summit Trail Advisors, LLC | 5,057 | $2.29M | 0.04% | −427−7.8% | Reduced |
| Machina Capital S.A.S. | 5,064 | $2.30M | 0.44% | −6,103−54.7% | Reduced |
| Westerkirk Capital Inc. | 5,071 | $2.30M | 0.22% | +429+9.2% | Added |
| Hager Investment Management Services, LLC | 5,084 | $2.30M | 1.26% | −188−3.6% | Reduced |
| Tiaa Trust, National Association | 5,129 | $2.33M | 0.01% | −153−2.9% | Reduced |
| Te Ahumairangi Investment Management Ltd | 5,135 | $2.33M | 0.42% | −590−10.3% | Reduced |
| Scotia Capital Inc. | 5,165 | $2.34M | 0.01% | −756−12.8% | Reduced |
| Sand Hill Global Advisors, LLC | 5,176 | $2.35M | 0.08% | −1,550−23.0% | Reduced |
| Parallel Advisors, LLC | 5,189 | $2.35M | 0.04% | +134+2.7% | Added |
| Bamco Inc | 5,200 | $2.36M | 0.01% | 00.0% | Unchanged |
| D.A. Davidson & Co. | 5,251 | $2.38M | 0.01% | +154+3.0% | Added |
| Wealthcare Advisory Partners LLC | 5,259 | $2.38M | 0.05% | +130+2.5% | Added |
| Vise Technologies, Inc. | 5,259 | $2.38M | 0.05% | +1,036+24.5% | Added |
| Nwam LLC | 5,038 | $2.40M | 0.13% | −39−0.8% | Reduced |
| Ballentine Partners, LLC | 5,290 | $2.40M | 0.03% | +200+3.9% | Added |
| Signaturefd, LLC | 5,305 | $2.41M | 0.04% | +202+4.0% | Added |
| Glenmede Trust Co NA | 5,339 | $2.42M | 0.01% | +5,339 | New |
| Cooper Financial Group | 5,341 | $2.42M | 0.26% | +3,021+130.2% | Added |
| Highview Capital Management LLC | 5,409 | $2.45M | 0.87% | −294−5.2% | Reduced |
| Burney Co | 5,468 | $2.48M | 0.08% | −1,163−17.5% | Reduced |
| Mediolanum International Funds Ltd | 5,487 | $2.49M | 0.02% | −3,057−35.8% | Reduced |
| Ascent Group, LLC | 5,495 | $2.49M | 0.09% | −1,124−17.0% | Reduced |
| BLI - Banque de Luxembourg Investments | 5,500 | $2.50M | 0.07% | −700−11.3% | Reduced |
| Wimmer Associates 1, LLC | 5,526 | $2.51M | 1.16% | +71+1.3% | Added |
| MASTERINVEST Kapitalanlage GmbH | 5,544 | $2.52M | 0.24% | 00.0% | Unchanged |
| Wedbush Securities Inc | 5,561 | $2.52M | 0.07% | −589−9.6% | Reduced |
| V-Square Quantitative Management LLC | 5,624 | $2.55M | 0.27% | +5,624 | New |
| Venturi Wealth Management, LLC | 5,630 | $2.55M | 0.11% | −158−2.7% | Reduced |
| Tudor Investment Corp Et Al | 5,641 | $2.56M | 0.01% | −45,733−89.0% | Reduced |
| GAMMA Investing LLC | 5,714 | $2.59M | 0.13% | +1,082+23.4% | Added |
| TD Waterhouse Canada Inc. | 5,731 | $2.60M | 0.02% | +134+2.4% | Added |
| Nemes Rush Group LLC | 5,737 | $2.60M | 0.24% | −13−0.2% | Reduced |
| RMR Wealth Builders | 5,789 | $2.62M | 0.21% | +466+8.8% | Added |
| Illumine Investment Management, LLC | 5,820 | $2.64M | 1.92% | −6−0.1% | Reduced |
| Bokf, NA | 5,867 | $2.66M | 0.04% | −1,171−16.6% | Reduced |
| Harbour Capital Advisors, LLC | 5,933 | $2.68M | 0.55% | −248−4.0% | Reduced |
| Plato Investment Management Ltd | 5,935 | $2.70M | 0.18% | −91−1.5% | Reduced |
| Cohen Klingenstein LLC | 6,000 | $2.72M | 0.08% | 00.0% | Unchanged |
| DCF Advisers, LLC | 6,000 | $2.72M | 0.90% | +6,000 | New |
| Coldstream Capital Management Inc | 6,002 | $2.72M | 0.04% | −404−6.3% | Reduced |
| Freedom Day Solutions, LLC | 6,027 | $2.73M | 0.74% | +213+3.7% | Added |
| Hall Laurie J Trustee | 6,030 | $2.73M | 0.91% | +80+1.3% | Added |
| Perigon Wealth Management, LLC | 6,044 | $2.74M | 0.05% | −64−1.0% | Reduced |
| Meeder Advisory Services, Inc. | 6,065 | $2.75M | 0.12% | +153+2.6% | Added |
| HighPoint Advisor Group LLC | 6,089 | $2.76M | 0.06% | +1,585+35.2% | Added |
| Univest Financial Corp | 6,097 | $2.76M | 0.15% | −1,267−17.2% | Reduced |
| Aureus Asset Management, LLC | 6,142 | $2.78M | 0.18% | +4,324+237.8% | Added |
| Kovack Advisors, Inc. | 6,191 | $2.81M | 0.13% | +5,044+439.8% | Added |
| Griffin Asset Management, Inc. | 6,195 | $2.81M | 0.30% | −25−0.4% | Reduced |
| First National Bank of Mount Dora, Trust Investment Services | 6,212 | $2.82M | 0.62% | +37+0.6% | Added |
| B&L Asset Management LLC | 6,237 | $2.83M | 1.27% | +188+3.1% | Added |
| Westview Management dba Westview Investment Advisors | 6,284 | $2.85M | 1.36% | +6,284 | New |
| Nikko Asset Management Americas, Inc. | 6,314 | $2.86M | 0.03% | −588−8.5% | Reduced |