Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Shepherd Street Advisors LLC | 2,995 | $1.36M | 1.30% | +2,995 | New |
| J. Safra Sarasin Holding AG | 3,000 | $1.36M | 0.02% | −827−21.6% | Reduced |
| United Asset Strategies, Inc. | 3,010 | $1.36M | 0.11% | +66+2.2% | Added |
| Hilltop Holdings Inc. | 3,015 | $1.37M | 0.08% | −1,919−38.9% | Reduced |
| WP Advisors, LLC | 3,018 | $1.37M | 0.34% | −190−5.9% | Reduced |
| AustralianSuper Pty Ltd | 3,032 | $1.37M | 0.01% | 00.0% | Unchanged |
| Patriot Financial Group Insurance Agency, LLC | 3,034 | $1.38M | 0.16% | −226−6.9% | Reduced |
| Aviso Financial Inc. | 3,052 | $1.38M | 0.05% | −113−3.6% | Reduced |
| Boston Private Wealth LLC | 3,061 | $1.39M | 0.08% | −4,354−58.7% | Reduced |
| Hartford Funds Management Co LLC | 3,073 | $1.39M | 0.11% | +1,512+96.9% | Added |
| IFP Advisors, Inc | 3,082 | $1.40M | 0.03% | +797+34.9% | Added |
| Arrow Financial Corp | 3,085 | $1.40M | 0.14% | −152−4.7% | Reduced |
| Stephens Inc | 3,094 | $1.40M | 0.02% | −470−13.2% | Reduced |
| Baker Tilly Wealth Management, LLC | 3,109 | $1.41M | 0.35% | +28+0.9% | Added |
| Pure Financial Advisors, Inc. | 3,110 | $1.41M | 0.02% | −220−6.6% | Reduced |
| Community Bank, N.A. | 3,127 | $1.42M | 0.17% | +265+9.3% | Added |
| Milestone Asset Management, LLC | 3,139 | $1.42M | 0.27% | +561+21.8% | Added |
| FRG Family Wealth Advisors LLC | 3,150 | $1.43M | 0.22% | −30−0.9% | Reduced |
| MN Wealth Advisors, LLC | 3,150 | $1.43M | 0.72% | +266+9.2% | Added |
| Sandro Wealth Management LLC | 3,167 | $1.44M | 1.19% | +3,167 | New |
| Murphy & Mullick Capital Management Corp | 3,186 | $1.44M | 1.04% | −38−1.2% | Reduced |
| Strategy Asset Managers LLC | 3,191 | $1.45M | 0.24% | +198+6.6% | Added |
| Procyon Private Wealth Partners, LLC | 3,206 | $1.45M | 0.07% | −139−4.2% | Reduced |
| Syon Capital LLC | 3,208 | $1.45M | 0.07% | +369+13.0% | Added |
| Institute for Wealth Management, LLC. | 3,215 | $1.46M | 0.15% | −8−0.2% | Reduced |
| MWA Asset Management | 3,216 | $1.46M | 0.81% | +18+0.6% | Added |
| ISAM Funds (UK) Ltd | 3,221 | $1.46M | 0.53% | +1,971+157.7% | Added |
| Ingalls & Snyder LLC | 3,227 | $1.46M | 0.05% | +12+0.4% | Added |
| Capstone Investment Advisors, LLC | 3,239 | $1.47M | 0.01% | −2,784−46.2% | Reduced |
| Hohimer Wealth Management, LLC | 3,251 | $1.47M | 0.20% | −18−0.6% | Reduced |
| DSG Capital Advisors, LLC | 3,380 | $1.48M | 0.23% | −185−5.2% | Reduced |
| Grange Capital, LLC | 3,279 | $1.49M | 1.43% | −275−7.7% | Reduced |
| Frank, Rimerman Advisors LLC | 3,282 | $1.49M | 0.09% | +162+5.2% | Added |
| Stratos Wealth Partners, LTD. | 3,299 | $1.50M | 0.02% | +207+6.7% | Added |
| Independent Advisor Alliance | 3,300 | $1.50M | 0.04% | +74+2.3% | Added |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 3,302 | $1.50M | 0.05% | +164+5.2% | Added |
| Sculati Wealth Management, LLC | 3,360 | $1.52M | 0.54% | +32+1.0% | Added |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 3,364 | $1.53M | 0.22% | +3,364 | New |
| Richard Bernstein Advisors LLC | 3,367 | $1.53M | 0.04% | −325−8.8% | Reduced |
| Norden Group LLC | 3,368 | $1.53M | 0.15% | +1,016+43.2% | Added |
| Berkshire Asset Management LLC | 3,379 | $1.53M | 0.07% | +9+0.3% | Added |
| Ifrah Financial Services, Inc. | 3,397 | $1.54M | 0.40% | −79−2.3% | Reduced |
| Savant Capital, LLC | 3,407 | $1.54M | 0.01% | +481+16.4% | Added |
| Wedmont Private Capital | 3,218 | $1.56M | 0.05% | −81−2.5% | Reduced |
| Triglav Skladi, D.O.O. | 3,450 | $1.56M | 0.10% | 00.0% | Unchanged |
| National Asset Management, Inc. | 3,455 | $1.57M | 0.07% | −270−7.2% | Reduced |
| Tealwood Asset Management Inc | 3,462 | $1.57M | 0.70% | −21−0.6% | Reduced |
| Intrust Bank NA | 3,473 | $1.57M | 0.13% | +211+6.5% | Added |
| Mutual Advisors, LLC | 3,476 | $1.58M | 0.03% | −346−9.1% | Reduced |
| Moors & Cabot, Inc. | 3,479 | $1.58M | 0.07% | −100−2.8% | Reduced |
| Panagora Asset Management Inc | 3,485 | $1.58M | 0.01% | +77+2.3% | Added |
| Simplex Trading, LLC | 3,511 | $1.59M | 0.04% | +1,908+119.0% | Added |
| Midwest Professional Planners, LTD. | 3,524 | $1.60M | 0.38% | +28+0.8% | Added |
| Clearstead Advisors, LLC | 3,527 | $1.60M | 0.02% | 00.0% | Unchanged |
| Phoenix Holdings Ltd. | 3,533 | $1.60M | 0.02% | −308−8.0% | Reduced |
| Sagespring Wealth Partners, LLC | 3,587 | $1.63M | 0.03% | +657+22.4% | Added |
| Advisory Resource Group | 3,619 | $1.64M | 0.29% | +335+10.2% | Added |
| F&V Capital Management, LLC | 3,645 | $1.65M | 0.35% | +3,645 | New |
| Quantitative Investment Management, LLC | 3,657 | $1.66M | 0.16% | +1,985+118.7% | Added |
| Founders Financial Securities LLC | 3,664 | $1.66M | 0.10% | +722+24.5% | Added |
| Dynamic Advisor Solutions LLC | 3,668 | $1.66M | 0.05% | −110−2.9% | Reduced |
| Mattern Capital Management, LLC | 3,689 | $1.67M | 0.20% | +377+11.4% | Added |
| Roberts Glore & Co Inc | 3,690 | $1.67M | 0.45% | −25−0.7% | Reduced |
| Lighthouse Financial LLC | 3,730 | $1.69M | 1.11% | 00.0% | Unchanged |
| Icon Wealth Advisors, LLC | 3,743 | $1.70M | 0.11% | +176+4.9% | Added |
| Jump Financial, LLC | 3,762 | $1.71M | 0.02% | −6,421−63.1% | Reduced |
| Nilsine Partners, LLC | 3,781 | $1.71M | 0.15% | +229+6.4% | Added |
| Alaethes Wealth LLC | 3,787 | $1.72M | 0.48% | −167−4.2% | Reduced |
| CWA Asset Management Group, LLC | 3,789 | $1.72M | 0.06% | +320+9.2% | Added |
| Sound View Wealth Advisors Group, LLC | 3,870 | $1.75M | 0.12% | +241+6.6% | Added |
| Snowden Capital Advisors LLC | 3,918 | $1.78M | 0.05% | +87+2.3% | Added |
| MBM Wealth Consultants, LLC | 3,925 | $1.78M | 0.42% | +275+7.5% | Added |
| Waterloo Capital, L.P. | 3,929 | $1.78M | 0.13% | +3,929 | New |
| Arkadios Wealth Advisors | 3,965 | $1.80M | 0.04% | +1,631+69.9% | Added |
| Choate Investment Advisors | 3,976 | $1.80M | 0.04% | −15−0.4% | Reduced |
| TCW Group Inc | 3,988 | $1.81M | 0.01% | +3,988 | New |
| Smartleaf Asset Management LLC | 3,985 | $1.81M | 0.07% | +752+23.3% | Added |
| Lipe & Dalton | 3,996 | $1.81M | 0.90% | −250−5.9% | Reduced |
| Jones Kertz & Associates, Inc. | 4,004 | $1.82M | 0.93% | +4,004 | New |
| Woodstock Corp | 4,005 | $1.82M | 0.16% | 00.0% | Unchanged |
| Clal Insurance Enterprises Holdings Ltd | 4,023 | $1.82M | 0.01% | −3−0.1% | Reduced |
| Mission Wealth Management, LP | 4,056 | $1.84M | 0.04% | +89+2.2% | Added |
| ICICI Prudential Asset Management Co Ltd | 4,071 | $1.85M | 0.22% | +134+3.4% | Added |
| Mattson Financial Services, LLC | 4,085 | $1.85M | 0.43% | +39+1.0% | Added |
| JT Stratford LLC | 4,094 | $1.86M | 0.24% | +119+3.0% | Added |
| S&CO Inc | 4,103 | $1.86M | 0.12% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 4,155 | $1.88M | 0.00% | +4,155 | New |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 3,978 | $1.89M | 0.02% | +28+0.7% | Added |
| SFMG, LLC | 4,162 | $1.89M | 0.13% | −393−8.6% | Reduced |
| Belpointe Asset Management LLC | 4,180 | $1.90M | 0.07% | −55−1.3% | Reduced |
| Waldron Private Wealth LLC | 4,184 | $1.90M | 0.07% | −116−2.7% | Reduced |
| 3Chopt Investment Partners, LLC | 4,186 | $1.90M | 0.43% | −247−5.6% | Reduced |
| Dymon Asia Capital (Singapore) Pte. Ltd. | 4,200 | $1.90M | 0.42% | +4,200 | New |
| Summit Global Investments | 4,204 | $1.91M | 0.11% | −770−15.5% | Reduced |
| Meiji Yasuda America Inc | 4,216 | $1.91M | 0.44% | +4,216 | New |
| Pallas Capital Advisors LLC | 4,241 | $1.92M | 0.06% | +1,353+46.8% | Added |
| Ostrum Asset Management | 4,249 | $1.93M | 0.09% | −1,170−21.6% | Reduced |
| Texas Yale Capital Corp. | 4,269 | $1.94M | 0.06% | +181+4.4% | Added |
| Oppenheimer & Co Inc | 4,272 | $1.94M | 0.03% | +668+18.5% | Added |
| Everence Capital Management Inc | 4,274 | $1.94M | 0.11% | 00.0% | Unchanged |