Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Beirne Wealth Consulting Services, LLC | 1,048 | $410.4K | 0.10% | +1,048 | New |
| Guardian Wealth Advisors, LLC | 1,051 | $411.4K | 0.03% | −1−0.1% | Reduced |
| Sage Capital Advisors,llc | 1,051 | $411.5K | 0.10% | +336+47.0% | Added |
| RMB Capital Management, LLC | 1,070 | $419.1K | 0.01% | −186−14.8% | Reduced |
| Optimize Financial Inc | 1,072 | $419.8K | 0.22% | +1,072 | New |
| Willner & Heller, LLC | 1,075 | $421.0K | 0.32% | −141−11.6% | Reduced |
| Chicago Partners Investment Group LLC | 1,007 | $425.3K | 0.01% | −117−10.4% | Reduced |
| Koss-Olinger Consulting, LLC | 957 | $426.0K | 0.04% | 00.0% | Unchanged |
| Invesco, LLC | 1,091 | $427.3K | 0.14% | 00.0% | Unchanged |
| Pekin Hardy Strauss, Inc. | 1,106 | $433.2K | 0.04% | +1,106 | New |
| Albion Financial Group | 1,109 | $434.3K | 0.03% | −4−0.4% | Reduced |
| Redhawk Wealth Advisors, Inc. | 1,110 | $434.7K | 0.05% | −4,158−78.9% | Reduced |
| Catalyst Financial Partners LLC | 1,114 | $436.3K | 0.05% | −56−4.8% | Reduced |
| Second Line Capital, LLC | 1,115 | $436.7K | 0.09% | +1,115 | New |
| Keel Point, LLC | 1,131 | $442.9K | 0.03% | −157−12.2% | Reduced |
| Williams Jones Wealth Management, LLC. | 1,134 | $444.1K | 0.01% | 00.0% | Unchanged |
| First Commonwealth Financial Corp | 1,135 | $444.4K | 0.07% | −67−5.6% | Reduced |
| Bridgewater Advisors Inc. | 1,069 | $444.9K | 0.03% | −28−2.6% | Reduced |
| PDS Planning, Inc | 1,143 | $447.6K | 0.03% | −100−8.0% | Reduced |
| LCM Capital Management Inc | 1,145 | $448.4K | 0.22% | −3−0.3% | Reduced |
| Kovack Advisors, Inc. | 1,147 | $449.2K | 0.04% | −133−10.4% | Reduced |
| Harbor Investment Advisory, LLC | 1,153 | $451.6K | 0.04% | −321−21.8% | Reduced |
| Keynote Financial Services LLC | 1,154 | $452.0K | 0.27% | +9+0.8% | Added |
| Modern Wealth Management, LLC | 1,166 | $456.5K | 0.01% | +105+9.9% | Added |
| Moneta Group Investment Advisors LLC | 1,177 | $460.8K | 0.00% | −69−5.5% | Reduced |
| Pitcairn Co | 1,178 | $461.4K | 0.04% | −279−19.1% | Reduced |
| Wrapmanager Inc | 1,179 | $461.7K | 0.14% | −595−33.5% | Reduced |
| Personal Cfo Solutions, LLC | 1,179 | $461.7K | 0.08% | +42+3.7% | Added |
| Towarzystwo Funduszy Inwestycyjnych Pzu SA | 1,189 | $465.7K | 0.11% | −805−40.4% | Reduced |
| Independent Financial Group, LLC | 1,191 | $466.4K | 0.01% | −155−11.5% | Reduced |
| Blueshift Asset Management, LLC | 1,213 | $475.1K | 0.15% | +1,213 | New |
| Gibbs Wealth Management | 1,216 | $476.2K | 0.11% | −217−15.1% | Reduced |
| Simplify Asset Management Inc. | 1,225 | $479.8K | 0.01% | +144+13.3% | Added |
| Total Clarity Wealth Management, Inc. | 1,232 | $482.5K | 0.13% | −30−2.4% | Reduced |
| Platform Technology Partners | 1,234 | $483.3K | 0.12% | 00.0% | Unchanged |
| Private Wealth Partners, LLC | 1,235 | $483.7K | 0.03% | −250−16.8% | Reduced |
| Paladin Wealth, LLC | 1,237 | $484.5K | 0.35% | −3−0.2% | Reduced |
| Accurate Wealth Management, LLC | 1,179 | $485.7K | 0.06% | +135+12.9% | Added |
| Rathbone Brothers plc | 1,244 | $487.2K | 0.00% | −7−0.6% | Reduced |
| Green Harvest Asset Management LLC | 1,248 | $488.8K | 0.01% | +28+2.3% | Added |
| Merrion Investment Management Co, LLC | 1,250 | $489.6K | 0.28% | 00.0% | Unchanged |
| ISAM Funds (UK) Ltd | 1,250 | $489.6K | 0.10% | +1,250 | New |
| Mayflower Financial Advisors, LLC | 1,253 | $490.7K | 0.06% | −160−11.3% | Reduced |
| Avidian Wealth Solutions, LLC | 1,257 | $492.3K | 0.02% | +65+5.5% | Added |
| Wealth Alliance | 1,259 | $493.1K | 0.05% | +1,259 | New |
| Perennial Investment Advisors, LLC | 1,263 | $494.6K | 0.04% | −60−4.5% | Reduced |
| Alta Advisers Ltd | 1,271 | $497.8K | 0.15% | 00.0% | Unchanged |
| Wakefield Asset Management LLLP | 1,276 | $499.7K | 0.14% | 00.0% | Unchanged |
| BOK Financial Private Wealth, Inc. | 1,279 | $500.9K | 0.03% | +21+1.7% | Added |
| 1248 Management, LLC | 1,281 | $501.7K | 0.28% | −514−28.6% | Reduced |
| Insigneo Advisory Services, LLC | 1,292 | $506.0K | 0.04% | −33−2.5% | Reduced |
| Fragasso Group Inc. | 1,257 | $506.9K | 0.03% | +3+0.2% | Added |
| Paces Ferry Wealth Advisors, LLC | 1,307 | $511.9K | 0.21% | +16+1.2% | Added |
| American Trust | 1,322 | $517.7K | 0.04% | +11+0.8% | Added |
| BankPlus Trust Department | 1,323 | $518.1K | 0.14% | −18−1.3% | Reduced |
| Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors | 1,330 | $520.9K | 0.06% | +90+7.3% | Added |
| Quadcap Wealth Management, LLC | 1,337 | $523.6K | 0.06% | +1,337 | New |
| Koshinski Asset Management, Inc. | 1,339 | $524.4K | 0.04% | +39+3.0% | Added |
| Hancock Whitney Corp | 1,339 | $524.4K | 0.01% | −23−1.7% | Reduced |
| Nabity-Jensen Investment Management Inc | 1,348 | $527.9K | 0.37% | 00.0% | Unchanged |
| Pine Valley Investments Ltd Liability Co | 1,350 | $528.7K | 0.03% | +9+0.7% | Added |
| Groesbeck Investment Management Corp | 1,359 | $532.0K | 1.04% | −500−26.9% | Reduced |
| Arete Wealth Advisors, LLC | 1,371 | $537.0K | 0.03% | −46−3.2% | Reduced |
| Great Diamond Partners, LLC | 1,372 | $537.3K | 0.10% | −404−22.7% | Reduced |
| Kessler Investment Group, LLC | 1,373 | $537.7K | 0.23% | 00.0% | Unchanged |
| Blue Chip Partners, Inc. | 1,375 | $538.5K | 0.04% | +269+24.3% | Added |
| Pinnacle Wealth Planning Services, Inc. | 1,380 | $540.3K | 0.06% | +512+59.0% | Added |
| Brookwood Investment Group LLC | 1,404 | $549.9K | 0.07% | −375−21.1% | Reduced |
| Savvy Advisors, Inc. | 1,419 | $555.7K | 0.03% | +512+56.4% | Added |
| Sovran Advisors, LLC | 1,328 | $557.6K | 0.05% | −57−4.1% | Reduced |
| NorthCrest Asset Manangement, LLC | 1,366 | $560.4K | 0.01% | −14−1.0% | Reduced |
| Pensionmark Financial Group, LLC | 1,431 | $560.5K | 0.01% | +178+14.2% | Added |
| Arcataur Capital Management LLC | 1,439 | $563.6K | 0.17% | −57−3.8% | Reduced |
| Legacy Wealth Asset Management, LLC | 1,442 | $564.7K | 0.14% | +26+1.8% | Added |
| SBI Securities Co., Ltd. | 1,446 | $566.3K | 0.01% | −42−2.8% | Reduced |
| Drive Wealth Management, LLC | 1,450 | $567.9K | 0.12% | +201+16.1% | Added |
| First Pacific Financial | 1,451 | $568.3K | 0.08% | −14−1.0% | Reduced |
| Checchi Capital Advisers, LLC | 1,461 | $572.2K | 0.04% | −333−18.6% | Reduced |
| Moloney Securities Asset Management, LLC | 1,461 | $572.2K | 0.07% | −37−2.5% | Reduced |
| Resonant Capital Advisors, LLC | 1,464 | $573.4K | 0.03% | −94−6.0% | Reduced |
| Renaissance Group LLC | 1,468 | $574.7K | 0.02% | −51−3.4% | Reduced |
| Alpha Family Trust | 1,485 | $581.6K | 0.27% | −235−13.7% | Reduced |
| J.W. Cole Advisors, Inc. | 1,487 | $582.4K | 0.01% | −97−6.1% | Reduced |
| Resources Investment Advisors, LLC. | 1,494 | $585.1K | 0.01% | −121−7.5% | Reduced |
| Exencial Wealth Advisors, LLC | 1,500 | $587.4K | 0.02% | −60−3.8% | Reduced |
| Legacy Capital Wealth Partners, LLC | 1,503 | $588.6K | 0.13% | +503+50.3% | Added |
| Spinnaker Trust | 1,505 | $589.4K | 0.03% | 00.0% | Unchanged |
| Ausdal Financial Partners, Inc. | 1,513 | $592.5K | 0.03% | +743+96.5% | Added |
| Fullerton Fund Management Co Ltd. | 1,522 | $596.1K | 0.02% | +1,522 | New |
| Kensington Investment Counsel, LLC | 1,526 | $597.6K | 0.24% | +23+1.5% | Added |
| Weatherly Asset Management L. P. | 1,531 | $599.6K | 0.05% | +1,531 | New |
| New England Research & Management, Inc. | 1,535 | $601.2K | 0.28% | +475+44.8% | Added |
| IHT Wealth Management, LLC | 1,542 | $604.0K | 0.02% | −5−0.3% | Reduced |
| Conning Inc. | 1,544 | $604.7K | 0.02% | 00.0% | Unchanged |
| Continuum Advisory, LLC | 1,546 | $605.5K | 0.06% | −193−11.1% | Reduced |
| Baxter Bros Inc | 1,549 | $606.6K | 0.07% | +108+7.5% | Added |
| Lantern Wealth Advisors, LLC | 1,550 | $607.0K | 0.32% | 00.0% | Unchanged |
| Prudent Man Advisors, LLC | 1,551 | $607.4K | 0.22% | −184−10.6% | Reduced |
| Advisors Capital Management, LLC | 1,552 | $607.9K | 0.01% | +226+17.0% | Added |
| Hartford Funds Management Co LLC | 1,561 | $612.0K | 0.05% | −193−11.0% | Reduced |