Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −13 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 156
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Private Trust Co NA | 532 | $208.4K | 0.02% | −454−46.0% | Reduced |
| Acropolis Investment Management, LLC | 469 | $208.8K | 0.01% | −13−2.7% | Reduced |
| Hanson & Doremus Investment Management | 534 | $209.0K | 0.03% | −36−6.3% | Reduced |
| Tillman Hartley LLC | 536 | $209.9K | 0.05% | 00.0% | Unchanged |
| Sound Income Strategies, LLC | 506 | $209.9K | 0.01% | +36+7.7% | Added |
| Regent Peak Wealth Advisors LLC | 536 | $209.9K | 0.04% | +536 | New |
| Focus Financial Network, Inc. | 539 | $211.1K | 0.01% | −67−11.1% | Reduced |
| Brookstone Capital Management | 539 | $211.1K | 0.00% | +539 | New |
| Blackhawk Capital Partners LLC. | 547 | $214.2K | 0.08% | +547 | New |
| Tritonpoint Wealth, LLC | 548 | $214.6K | 0.02% | −53−8.8% | Reduced |
| Nvest Financial, LLC | 549 | $215.0K | 0.12% | +36+7.0% | Added |
| Custom Index Systems, LLC | 550 | $215.4K | 0.06% | 00.0% | Unchanged |
| Columbia Asset Management | 553 | $216.6K | 0.04% | +55+11.0% | Added |
| Kesler, Norman & Wride, LLC | 538 | $216.7K | 0.04% | +538 | New |
| Relyea Zuckerberg Hanson LLC | 554 | $217.0K | 0.02% | −83−13.0% | Reduced |
| Monetary Management Group Inc | 555 | $217.4K | 0.05% | 00.0% | Unchanged |
| Park Place Capital Corp | 555 | $217.4K | 0.05% | +279+101.1% | Added |
| StoneX Group Inc. | 555 | $217.4K | 0.01% | +555 | New |
| BCJ Capital Management, LLC | 556 | $217.8K | 0.01% | +20+3.7% | Added |
| Warren Street Wealth Advisors, LLC | 559 | $218.9K | 0.07% | −50−8.2% | Reduced |
| Kingsview Wealth Management, LLC | 561 | $219.7K | 0.00% | +62+12.4% | Added |
| Sageworth Trust Co | 561 | $219.7K | 0.01% | +561 | New |
| Chesley Taft & Associates LLC | 563 | $220.5K | 0.01% | −33−5.5% | Reduced |
| Asset Allocation & Management Company, LLC | 567 | $222.0K | 0.09% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 568 | $222.5K | 0.00% | −24−4.1% | Reduced |
| Gsa Capital Partners LLP | 569 | $223.0K | 0.02% | −1,002−63.8% | Reduced |
| Clark Capital Management Group, Inc. | 572 | $224.0K | 0.00% | +91+18.9% | Added |
| Putney Financial Group LLC | 574 | $224.8K | 0.22% | −145−20.2% | Reduced |
| International Assets Investment Management, LLC | 498 | $225.2K | 0.02% | 00.0% | Unchanged |
| Western Wealth Management, LLC | 576 | $225.7K | 0.01% | −45−7.2% | Reduced |
| Kelly Lawrence W & Associates Inc | 585 | $229.1K | 0.06% | −20−3.3% | Reduced |
| Centurion Wealth Management LLC | 585 | $229.1K | 0.05% | +84+16.8% | Added |
| JGP Global Gestao de Recursos Ltda. | 586 | $229.5K | 0.13% | +5+0.9% | Added |
| Global Trust Asset Management, LLC | 586 | $229.5K | 0.10% | +18+3.2% | Added |
| Fort Point Capital Partners LLC | 587 | $229.9K | 0.03% | −121−17.1% | Reduced |
| Empower Advisory Group, LLC | 587 | $229.9K | 0.00% | +38+6.9% | Added |
| Costello Asset Management, INC | 589 | $230.7K | 0.08% | −100−14.5% | Reduced |
| Icapital Wealth LLC | 591 | $231.5K | 0.13% | 00.0% | Unchanged |
| BKD Wealth Advisors, LLC | 592 | $231.9K | 0.00% | −1,008−63.0% | Reduced |
| William Blair Investment Management, LLC | 596 | $233.4K | 0.00% | −22,012−97.4% | Reduced |
| Coastline Trust Co | 597 | $233.8K | 0.03% | −3,145−84.0% | Reduced |
| Berman McAleer LLC | 597 | $233.8K | 0.03% | +597 | New |
| Bartlett & Co. Wealth Management LLC | 600 | $235.0K | 0.00% | +13+2.2% | Added |
| Aries Wealth Management | 605 | $236.9K | 0.06% | 00.0% | Unchanged |
| Sanibel Captiva Trust Company, Inc. | 607 | $237.7K | 0.01% | −10−1.6% | Reduced |
| Investment Advisory Group, LLC | 609 | $238.5K | 0.06% | −103−14.5% | Reduced |
| Main Street Financial Solutions, LLC | 609 | $238.5K | 0.02% | +609 | New |
| Diversified Trust Co | 611 | $239.3K | 0.00% | −2−0.3% | Reduced |
| Boothbay Fund Management, LLC | 611 | $239.3K | 0.01% | +81+15.3% | Added |
| Banque Transatlantique SA | 614 | $240.3K | 0.01% | −162−20.9% | Reduced |
| First American Bank | 614 | $240.5K | 0.02% | 00.0% | Unchanged |
| Sittner & Nelson, LLC | 615 | $240.9K | 0.09% | 00.0% | Unchanged |
| Fox Run Management, L.L.C. | 616 | $241.3K | 0.04% | +616 | New |
| Nicolet Bankshares Inc | 617 | $241.6K | 0.04% | 00.0% | Unchanged |
| Inscription Capital, LLC | 620 | $242.8K | 0.03% | −21−3.3% | Reduced |
| Midwest Trust Co | 620 | $242.8K | 0.00% | +49+8.6% | Added |
| Grimes & Company, Inc. | 621 | $243.3K | 0.01% | −87−12.3% | Reduced |
| KPP Advisory Services LLC | 626 | $245.2K | 0.04% | +626 | New |
| Financial Engines Advisors L.L.C. | 628 | $245.9K | 0.00% | +3+0.5% | Added |
| Moss Adams Wealth Advisors LLC | 628 | $246.1K | 0.02% | −123−16.4% | Reduced |
| Capital Performance Advisors LLP | 629 | $246.3K | 0.04% | +28+4.7% | Added |
| Bryn Mawr Trust Co | 629 | $246.3K | 0.01% | −3,035−82.8% | Reduced |
| Cim, LLC | 631 | $247.1K | 0.03% | −2−0.3% | Reduced |
| ICW Investment Advisors LLC | 632 | $247.4K | 0.09% | +28+4.6% | Added |
| Epoch Investment Partners, Inc. | 634 | $248.3K | 0.00% | −60,392−99.0% | Reduced |
| Eastern Bank | 638 | $249.9K | 0.00% | −997−61.0% | Reduced |
| May Hill Capital, LLC | 640 | $250.7K | 0.07% | −33−4.9% | Reduced |
| Clarity Financial LLC | 645 | $252.6K | 0.03% | +645 | New |
| Regions Financial Corp | 647 | $253.4K | 0.00% | −90−12.2% | Reduced |
| Johnson Financial Group, Inc. | 648 | $253.8K | 0.01% | +224+52.8% | Added |
| Fox Hill Wealth Management | 649 | $254.2K | 0.12% | −34−5.0% | Reduced |
| Lombard Odier Asset Management (USA) Corp | 651 | $255.0K | 0.06% | +651 | New |
| Turtle Creek Wealth Advisors, LLC | 653 | $255.7K | 0.02% | −124−16.0% | Reduced |
| Mason & Associates Inc | 655 | $256.5K | 0.05% | +655 | New |
| One Capital Management, LLC | 656 | $256.9K | 0.01% | −110−14.4% | Reduced |
| Nautilus Advisors LLC | 660 | $258.5K | 0.17% | −41−5.8% | Reduced |
| Abundance Wealth Counselors | 662 | $259.3K | 0.04% | −84−11.3% | Reduced |
| Cromwell Holdings LLC | 663 | $259.7K | 0.14% | +7+1.1% | Added |
| Symphony Financial, Ltd. Co. | 672 | $260.7K | 0.03% | −1,681−71.4% | Reduced |
| Fairfield, Bush & Co. | 671 | $262.8K | 0.13% | −20−2.9% | Reduced |
| Opinicus Capital, Inc. | 673 | $263.6K | 0.18% | −149−18.1% | Reduced |
| Whittier Trust Co of Nevada Inc | 657 | $265.0K | 0.01% | +113+20.8% | Added |
| Lion Street Advisors, LLC | 1,435 | $265.4K | 0.09% | +843+142.4% | Added |
| KC Investment Advisors, LLC | 630 | $265.5K | 0.07% | −42−6.3% | Reduced |
| Mesirow Financial Investment Management, Inc. | 679 | $265.9K | 0.00% | +55+8.8% | Added |
| Zullo Investment Group, Inc. | 679 | $265.9K | 0.10% | +2+0.3% | Added |
| Sivia Capital Partners, LLC | 680 | $266.3K | 0.08% | +23+3.5% | Added |
| William Mack & Associates, Inc. | 682 | $267.1K | 0.14% | 00.0% | Unchanged |
| Sentry Investment Management LLC | 640 | $270.0K | 0.18% | −181−22.0% | Reduced |
| Facet Wealth, Inc. | 691 | $270.6K | 0.01% | +158+29.6% | Added |
| HBK Sorce Advisory LLC | 664 | $271.0K | 0.01% | −26−3.8% | Reduced |
| Parkside Financial Bank & Trust | 694 | $271.8K | 0.02% | −190−21.5% | Reduced |
| Onefund, LLC | 695 | $272.2K | 0.18% | +27+4.0% | Added |
| UMA Financial Services, Inc. | 698 | $273.4K | 0.04% | +157+29.0% | Added |
| Daymark Wealth Partners, LLC | 699 | $273.8K | 0.01% | +247+54.6% | Added |
| Childress Capital Advisors, LLC | 708 | $277.3K | 0.05% | −52−6.8% | Reduced |
| Meridian Wealth Management, LLC | 709 | $277.7K | 0.01% | +2+0.3% | Added |
| Qsemble Capital Management, LP | 709 | $277.7K | 0.03% | +709 | New |
| Essex Savings Bank | 712 | $278.8K | 0.06% | +8+1.1% | Added |
| Leeward Financial Partners, LLC | 716 | $280.4K | 0.08% | 00.0% | Unchanged |