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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,523
−12 vs. Q2 2025
Shares held
232.3M
−4.81M (−2.0%) vs. Q2 2025
Total value
$90.8B
−$14.7B (−14.0%) vs. Q2 2025
New holders
143
553 more added
Sold out
155
617 more reduced

28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 1,523 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ3 2025: $90.8B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.

Institutions holding VRTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
IFC Advisors LLC0$00.00%−555−100.0%Sold out
Fielder Capital Group LLC0$00.00%−553−100.0%Sold out
PFW Advisors LLC0$00.00%−545−100.0%Sold out
MBL Wealth, LLC0$00.00%−542−100.0%Sold out
Stonebrook Private Inc.0$00.00%−532−100.0%Sold out
Marshall Financial Group LLC0$00.00%−512−100.0%Sold out
Carr Financial Group Corp0$00.00%−528−100.0%Sold out
Integral Investment Advisors, Inc.0$00.00%−525−100.0%Sold out
Five Oceans Advisors0$00.00%−523−100.0%Sold out
Abel Hall, LLC0$00.00%−521−100.0%Sold out
VisionPoint Advisory Group, LLC0$00.00%−520−100.0%Sold out
Teamwork Financial Advisors, LLC0$00.00%−519−100.0%Sold out
MBB Public Markets I LLC0$00.00%−510−100.0%Sold out
US Asset Management LLC0$00.00%−507−100.0%Sold out
Diversified Enterprises, LLC0$00.00%−505−100.0%Sold out
Mengis Capital Management, Inc.0$00.00%−500−100.0%Sold out
Arlington Financial Advisors, LLC0$00.00%−500−100.0%Sold out
McHugh Group, LLC0$00.00%−500−100.0%Sold out
GM Advisory Group, Inc.0$00.00%−499−100.0%Sold out
Beaumont Financial Advisors, LLC0$00.00%−496−100.0%Sold out
Lewis Asset Management, LLC0$00.00%−495−100.0%Sold out
Waters Parkerson & Co., LLC0$00.00%−489−100.0%Sold out
Boston Trust Walden Corp0$00.00%−485−100.0%Sold out
Loudon Investment Management, LLC0$00.00%−485−100.0%Sold out
Roberts Capital Advisors, LLC0$00.00%−485−100.0%Sold out
Axq Capital, LP0$00.00%−484−100.0%Sold out
Farmers & Merchants Trust Co of Long Beach0$00.00%−484−100.0%Sold out
Ignite Planners, LLC0$00.00%−462−100.0%Sold out
SeaCrest Wealth Management, LLC0$00.00%−474−100.0%Sold out
Eagle Wealth Strategies LLC0$00.00%−473−100.0%Sold out
Sage Capital Management, LLC0$00.00%−472−100.0%Sold out
Blue Barn Wealth, LLC0$00.00%−470−100.0%Sold out
PFG Advisors0$00.00%−466−100.0%Sold out
Klingman & Associates, LLC0$00.00%−466−100.0%Sold out
PKS Advisory Services, LLC0$00.00%−465−100.0%Sold out
Haverford Trust Co0$00.00%−463−100.0%Sold out
Aprio Wealth Management, LLC0$00.00%−463−100.0%Sold out
Commonwealth Financial Services, LLC0$00.00%−462−100.0%Sold out
Foster Group, Inc.0$00.00%−462−100.0%Sold out
Mainsail Asset Management, LLC0$00.00%−462−100.0%Sold out
Joel Isaacson & Co., LLC0$00.00%−454−100.0%Sold out
Stratos Wealth Advisors, LLC0$00.00%−454−100.0%Sold out
Foster & Motley Inc0$00.00%−451−100.0%Sold out
Park Square Financial Group, LLC0$00.00%−398−100.0%Sold out
Silver Oak Securities, Inc0$00.00%−381−100.0%Sold out
T. Rowe Price Investment Management, Inc.0$00.00%−297−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−306−100.0%Sold out
Barnes Dennig Private Wealth Management LLC0$00.00%−251−100.0%Sold out
Antipodes Partners Ltd0$00.00%−241−100.0%Sold out
Opal Wealth Advisors, LLC0$00.00%−164−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−160−100.0%Sold out
Beacon Capital Management, LLC0$00.00%−150−100.0%Sold out
Sierra Ocean, LLC0$00.00%−146−100.0%Sold out
Atticus Wealth Management, LLC0$00.00%−143−100.0%Sold out
Transce3nd, LLC0$00.00%−117−100.0%Sold out
NewSquare Capital LLC0$00.00%−115−100.0%Sold out
Total Investment Management Inc0$00.00%−75−100.0%Sold out
Bank of Jackson Hole Trust0$00.00%−53−100.0%Sold out
DAGCO, Inc.0$00.00%−47−100.0%Sold out
Banque de Luxembourg S.A.0$00.00%−40−100.0%Sold out
VSM Wealth Advisory, LLC0$00.00%−38−100.0%Sold out
Bellwether Advisors, LLC0$00.00%−37−100.0%Sold out
Armstrong Advisory Group, Inc0$00.00%−32−100.0%Sold out
GFG Capital, LLC0$00.00%−31−100.0%Sold out
Pineridge Advisors LLC0$00.00%−27−100.0%Sold out
WealthTrak Capital Management LLC0$00.00%−16−100.0%Sold out
Newbridge Financial Services Group, Inc.0$00.00%−14−100.0%Sold out
Eq Wealth Advisors, LLC0$00.00%−12−100.0%Sold out
Traub Capital Management LLC0$00.00%−8−100.0%Sold out
Stephens Consulting, LLC0$00.00%−7−100.0%Sold out
Bank of New Hampshire0$00.00%−7−100.0%Sold out
Garde Capital, Inc.0$00.00%−5−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−4−100.0%Sold out
Tobam0$00.00%−3−100.0%Sold out
Wood Tarver Financial Group, LLC0$00.00%−4−100.0%Sold out
Medallion Wealth Advisors, LLC0$00.00%−2−100.0%Sold out
IMA Wealth, Inc.0$00.00%−2−100.0%Sold out
Proathlete Wealth Management LLC0$00.00%−2−100.0%Sold out
Norges Bank––––Not filed
MEAG MUNICH ERGO, Kapitalanlagegesellschaft mbH––––Not filed
CIBC World Markets Corp––––Not filed
Congress Wealth Management LLC––––Not filed
Churchill Management Corp––––Not filed
First Horizon Advisors, Inc.––––Not filed
NBW Capital LLC––––Not filed
Avantax Advisory Services, Inc.––––Not filed
Forte Capital LLC––––Not filed
EP Wealth Advisors, LLC––––Not filed
E Fund Management Co., Ltd.––––Not filed
Northeast Financial Consultants Inc––––Not filed
Atria Wealth Solutions, Inc.––––Not filed
Graypoint LLC––––Not filed
My Legacy Advisors, LLC––––Not filed
Scott Marsh Financial, LLC––––Not filed
Breed's Hill Capital LLC––––Not filed
Capital Market Strategies LLC––––Not filed
Keudell/Morrison Wealth Management––––Not filed
Centricity Wealth Management, LLC––––Not filed
Atlas Capital Advisors LLC––––Not filed
PrairieView Partners, LLC––––Not filed