Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Victory Capital Management Inc | 2,247,566 | $787.3M | 0.49% | +92,402+4.3% | Added |
| Invesco Ltd. | 2,096,797 | $821.2M | 0.13% | +112,751+5.7% | Added |
| Janus Henderson Group PLC | 2,119,107 | $829.9M | 0.38% | −500,427−19.1% | Reduced |
| Ameriprise Financial Inc | 2,276,927 | $891.7M | 0.21% | +95,565+4.4% | Added |
| Northern Trust Corp | 2,627,887 | $1.03B | 0.13% | −30,694−1.2% | Reduced |
| Clearbridge Investments, LLC | 2,645,764 | $1.04B | 0.78% | +1,117,900+73.2% | Added |
| Bank of America Corp | 2,840,424 | $1.11B | 0.08% | +32,807+1.2% | Added |
| UBS Asset Management Americas Inc | 2,887,117 | $1.13B | 0.25% | −180,356−5.9% | Reduced |
| Price T Rowe Associates Inc | 3,043,805 | $1.19B | 0.13% | −116,065−3.7% | Reduced |
| Morgan Stanley | 3,108,405 | $1.22B | 0.07% | −223,034−6.7% | Reduced |
| FMR LLC | 3,303,768 | $1.29B | 0.07% | −3,102,604−48.4% | Reduced |
| Jennison Associates LLC | 3,454,947 | $1.35B | 0.79% | −2,696,558−43.8% | Reduced |
| Loomis Sayles & Co L P | 4,122,128 | $1.61B | 1.92% | +308,750+8.1% | Added |
| Alliancebernstein L.P. | 4,522,586 | $1.77B | 0.56% | +144,266+3.3% | Added |
| Capital International Investors | 4,689,059 | $1.84B | 0.30% | +2,053,156+77.9% | Added |
| Wellington Management Group LLP | 4,772,042 | $1.87B | 0.33% | −41,344−0.9% | Reduced |
| Geode Capital Management, LLC | 5,973,745 | $2.33B | 0.15% | +44,998+0.8% | Added |
| JPMorgan Chase & Co | 6,434,778 | $2.52B | 0.16% | +565,417+9.6% | Added |
| State Street Corp | 11,606,000 | $4.55B | 0.16% | −169,227−1.4% | Reduced |
| Capital Research Global Investors | 16,553,281 | $6.48B | 1.22% | +444,990+2.8% | Added |
| BlackRock, Inc. | 22,253,047 | $8.72B | 0.15% | +381,102+1.7% | Added |
| Vanguard Group Inc | 24,216,865 | $9.48B | 0.14% | +243,088+1.0% | Added |
| Capital World Investors | 25,910,587 | $10.1B | 1.39% | −2,821,556−9.8% | Reduced |
| Artisan Partners Limited Partnership | 0 | $0 | 0.00% | −650,259−100.0% | Sold out |
| OrbiMed Advisors LLC | 0 | $0 | 0.00% | −210,287−100.0% | Sold out |
| AXA S.A. | 0 | $0 | 0.00% | −171,270−100.0% | Sold out |
| Westwood Holdings Group Inc. | 0 | $0 | 0.00% | −154,217−100.0% | Sold out |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −87,500−100.0% | Sold out |
| Capitolis Liquid Global Markets LLC | 0 | $0 | 0.00% | −71,000−100.0% | Sold out |
| Zurich Insurance Group Ltd | 0 | $0 | 0.00% | −52,372−100.0% | Sold out |
| Steel Peak Wealth Management LLC | 0 | $0 | 0.00% | −22,594−100.0% | Sold out |
| Bleakley Financial Group, LLC | 0 | $0 | 0.00% | −13,931−100.0% | Sold out |
| BTC Capital Management, Inc. | 0 | $0 | 0.00% | −11,928−100.0% | Sold out |
| Lockheed Martin Investment Management Co | 0 | $0 | 0.00% | −10,860−100.0% | Sold out |
| Diadema Partners LP | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Coppell Advisory Solutions LLC | 0 | $0 | 0.00% | −6,686−100.0% | Sold out |
| Draper Asset Management, LLC | 0 | $0 | 0.00% | −6,500−100.0% | Sold out |
| Broadleaf Partners, LLC | 0 | $0 | 0.00% | −6,018−100.0% | Sold out |
| V-Square Quantitative Management LLC | 0 | $0 | 0.00% | −5,970−100.0% | Sold out |
| Segment Wealth Management, LLC | 0 | $0 | 0.00% | −5,843−100.0% | Sold out |
| Tower View Investment Management & Research LLC | 0 | $0 | 0.00% | −5,193−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −5,141−100.0% | Sold out |
| Genus Capital Management Inc. | 0 | $0 | 0.00% | −4,370−100.0% | Sold out |
| Eqis Capital Management, Inc. | 0 | $0 | 0.00% | −4,110−100.0% | Sold out |
| Laffer Tengler Investments | 0 | $0 | 0.00% | −3,926−100.0% | Sold out |
| Abc Arbitrage SA | 0 | $0 | 0.00% | −3,221−100.0% | Sold out |
| L & S Advisors Inc | 0 | $0 | 0.00% | −3,146−100.0% | Sold out |
| Dana Investment Advisors, Inc. | 0 | $0 | 0.00% | −2,507−100.0% | Sold out |
| Baader Bank INC | 0 | $0 | 0.00% | −2,357−100.0% | Sold out |
| Legacy Bridge, LLC | 0 | $0 | 0.00% | −2,332−100.0% | Sold out |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −2,303−100.0% | Sold out |
| Advisors Preferred, LLC | 0 | $0 | 0.00% | −2,200−100.0% | Sold out |
| Veracity Capital LLC | 0 | $0 | 0.00% | −1,994−100.0% | Sold out |
| Holt Capital Advisors, L.L.C. dba Holt Capital Partners, L.P. | 0 | $0 | 0.00% | −1,977−100.0% | Sold out |
| Prossimo Advisors, LLC | 0 | $0 | 0.00% | −1,975−100.0% | Sold out |
| Bryce Point Capital, LLC | 0 | $0 | 0.00% | −1,956−100.0% | Sold out |
| Proficio Capital Partners LLC | 0 | $0 | 0.00% | −1,955−100.0% | Sold out |
| Menard Financial Group LLC | 0 | $0 | 0.00% | −1,951−100.0% | Sold out |
| Legal Advantage Investments, Inc. | 0 | $0 | 0.00% | −1,848−100.0% | Sold out |
| Capital Advisors Wealth Management, LLC | 0 | $0 | 0.00% | −1,821−100.0% | Sold out |
| Lee Johnson Capital Management, LLC | 0 | $0 | 0.00% | −1,619−100.0% | Sold out |
| Frisch Financial Group, Inc. | 0 | $0 | 0.00% | −1,614−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −1,572−100.0% | Sold out |
| Holderness Investments Co | 0 | $0 | 0.00% | −1,497−100.0% | Sold out |
| Avantax Planning Partners, Inc. | 0 | $0 | 0.00% | −1,489−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −1,353−100.0% | Sold out |
| Whalen Wealth Management Inc. | 0 | $0 | 0.00% | −1,324−100.0% | Sold out |
| TrueWealth Advisors, LLC | 0 | $0 | 0.00% | −1,223−100.0% | Sold out |
| Holocene Advisors, LP | 0 | $0 | 0.00% | −1,216−100.0% | Sold out |
| Orrstown Financial Services Inc | 0 | $0 | 0.00% | −1,137−100.0% | Sold out |
| Parallax Volatility Advisers, L.P. | 0 | $0 | 0.00% | −1,046−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −1,045−100.0% | Sold out |
| TFB Advisors LLC | 0 | $0 | 0.00% | −1,039−100.0% | Sold out |
| Investment House LLC | 0 | $0 | 0.00% | −969−100.0% | Sold out |
| MQS Management LLC | 0 | $0 | 0.00% | −950−100.0% | Sold out |
| Dohj, LLC | 0 | $0 | 0.00% | −857−100.0% | Sold out |
| J2 Capital Management Inc | 0 | $0 | 0.00% | −928−100.0% | Sold out |
| Severin Investments, LLC | 0 | $0 | 0.00% | −867−100.0% | Sold out |
| WSFS Capital Management, LLC | 0 | $0 | 0.00% | −826−100.0% | Sold out |
| Zhang Financial LLC | 0 | $0 | 0.00% | −792−100.0% | Sold out |
| ICONIQ Capital, LLC | 0 | $0 | 0.00% | −790−100.0% | Sold out |
| Norris Financial Group, LLC | 0 | $0 | 0.00% | −736−100.0% | Sold out |
| Bourgeon Capital Management LLC | 0 | $0 | 0.00% | −735−100.0% | Sold out |
| Wedgewood Investors Inc | 0 | $0 | 0.00% | −720−100.0% | Sold out |
| Ewa, LLC | 0 | $0 | 0.00% | −681−100.0% | Sold out |
| Guerra Pan Advisors, LLC | 0 | $0 | 0.00% | −680−100.0% | Sold out |
| Perpetual Ltd | 0 | $0 | 0.00% | −679−100.0% | Sold out |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −677−100.0% | Sold out |
| Stanley-Laman Group, Ltd. | 0 | $0 | 0.00% | −668−100.0% | Sold out |
| Syverson Strege & Co | 0 | $0 | 0.00% | −635−100.0% | Sold out |
| ASB Consultores, LLC | 0 | $0 | 0.00% | −608−100.0% | Sold out |
| Resurgent Financial Advisors LLC | 0 | $0 | 0.00% | −607−100.0% | Sold out |
| Corient IA LLC | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Whipplewood Advisors, LLC | 0 | $0 | 0.00% | −589−100.0% | Sold out |
| RFG Advisory, LLC | 0 | $0 | 0.00% | −571−100.0% | Sold out |
| TBH Global Asset Management, LLC | 0 | $0 | 0.00% | −569−100.0% | Sold out |
| Green Alpha Advisors, LLC | 0 | $0 | 0.00% | −565−100.0% | Sold out |
| Pinebridge Investments, L.P. | 0 | $0 | 0.00% | −562−100.0% | Sold out |
| Kingswood Wealth Advisors, LLC | 0 | $0 | 0.00% | −557−100.0% | Sold out |
| FSM Wealth Advisors, LLC | 0 | $0 | 0.00% | −538−100.0% | Sold out |