Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 1 sale; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Quantinno Capital Management LP | 55,641 | $21.8M | 0.06% | +9,319+20.1% | Added |
| Harvest Fund Management Co., Ltd | 50,671 | $21.8M | 0.92% | +1,156+2.3% | Added |
| Nisa Investment Advisors, LLC | 55,778 | $21.8M | 0.08% | −9,639−14.7% | Reduced |
| AIA Group Ltd | 56,054 | $22.0M | 0.39% | +11,570+26.0% | Added |
| Amalgamated Bank | 56,514 | $22.1M | 0.16% | +779+1.4% | Added |
| Moody Lynn & Lieberson, LLC | 56,559 | $22.2M | 1.19% | −1,518−2.6% | Reduced |
| Zacks Investment Management | 58,026 | $22.7M | 0.18% | +3,710+6.8% | Added |
| Commonwealth Equity Services, LLC | 58,285 | $22.8M | 0.03% | −1,113−1.9% | Reduced |
| SG Americas Securities, LLC | 60,062 | $23.5M | 0.09% | −55,578−48.1% | Reduced |
| Foster Dykema Cabot & Partners, LLC | 60,689 | $23.8M | 1.56% | −234−0.4% | Reduced |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 61,569 | $24.1M | 0.12% | −1,412−2.2% | Reduced |
| Rakuten Investment Management, Inc. | 242,462 | $24.1M | 0.09% | +242,462 | New |
| Credit Agricole S A | 62,387 | $24.4M | 0.08% | +62,387 | New |
| Davidson Investment Advisors | 62,421 | $24.4M | 1.04% | −1,268−2.0% | Reduced |
| AMF Pensionsforsakring AB | 62,462 | $24.5M | 0.16% | −2,243−3.5% | Reduced |
| Xponance, Inc. | 62,491 | $24.5M | 0.19% | −109−0.2% | Reduced |
| GF Fund Management Co. Ltd. | 62,791 | $24.6M | 0.45% | +474+0.8% | Added |
| Swiss Life Asset Management Ltd | 63,945 | $25.0M | 0.13% | +6,045+10.4% | Added |
| Czech National Bank | 65,118 | $25.5M | 0.18% | +2,348+3.7% | Added |
| Jupiter Asset Management Ltd | 65,619 | $25.7M | 0.22% | +65,619 | New |
| Gateway Investment Advisers LLC | 65,926 | $25.8M | 0.25% | +132+0.2% | Added |
| Pacer Advisors, Inc. | 66,501 | $26.0M | 0.07% | +26,543+66.4% | Added |
| Nissay Asset Management Corp | 66,657 | $26.1M | 0.14% | +1,019+1.6% | Added |
| Daiwa Securities Group Inc. | 67,227 | $26.3M | 0.09% | −8,605−11.3% | Reduced |
| Susquehanna International Group, LLP | 67,683 | $26.5M | 0.04% | +5,474+8.8% | Added |
| Comerica Bank | 68,025 | $26.6M | 0.10% | +3,350+5.2% | Added |
| Erste Asset Management GmbH | 67,517 | $26.7M | 0.26% | −6,386−8.6% | Reduced |
| Nomura Holdings Inc | 68,254 | $26.7M | 0.12% | +66,650+4,155.2% | Added |
| Trillium Asset Management, LLC | 68,385 | $26.8M | 0.71% | +6,911+11.2% | Added |
| The PNC Financial Services Group, Inc. | 69,772 | $27.3M | 0.02% | −6,384−8.4% | Reduced |
| Motley Fool Wealth Management, LLC | 71,349 | $27.9M | 1.89% | +17,436+32.3% | Added |
| State of Michigan Retirement System | 72,023 | $28.2M | 0.14% | −500−0.7% | Reduced |
| Arizona State Retirement System | 74,994 | $29.4M | 0.16% | −100−0.1% | Reduced |
| Migdal Insurance & Financial Holdings Ltd. | 75,000 | $29.4M | 0.32% | +75,000 | New |
| MetLife Investment Management | 75,807 | $29.7M | 0.14% | −1,341−1.7% | Reduced |
| Beacon Investment Advisory Services, Inc. | 76,142 | $29.8M | 1.25% | −889−1.2% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 73,469 | $30.1M | 0.05% | −9,172−11.1% | Reduced |
| Janney Montgomery Scott LLC | 77,456 | $30.3M | 0.07% | +5,566+7.7% | Added |
| Cetera Investment Advisers | 77,714 | $30.4M | 0.04% | +17,518+29.1% | Added |
| Thrivent Financial for Lutherans | 78,270 | $30.7M | 0.06% | −9,932−11.3% | Reduced |
| Hardman Johnston Global Advisors LLC | 79,152 | $31.0M | 1.52% | −29,073−26.9% | Reduced |
| Banco Santander, S.A. | 79,406 | $31.1M | 0.28% | +9,218+13.1% | Added |
| Tang Capital Management LLC | 80,000 | $31.3M | 1.21% | +70,000+700.0% | Added |
| Kovitz Investment Group Partners, LLC | 80,587 | $31.6M | 0.12% | +48,544+151.5% | Added |
| STRS Ohio | 80,625 | $31.6M | 0.12% | −32,133−28.5% | Reduced |
| CIBC Asset Management Inc | 81,005 | $31.7M | 0.09% | +190.0% | Added |
| Rafferty Asset Management, LLC | 81,128 | $31.8M | 0.10% | +6,020+8.0% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 83,846 | $32.8M | 0.06% | −14,715−14.9% | Reduced |
| Advisor Group Holdings, Inc. | 84,250 | $33.0M | 0.05% | +33,922+67.4% | Added |
| Bank of Nova Scotia | 86,252 | $33.8M | 0.06% | +36,643+73.9% | Added |
| State of Tennessee, Treasury Department | 86,761 | $34.0M | 0.11% | −18,998−18.0% | Reduced |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 89,622 | $35.1M | 0.30% | −1,466−1.6% | Reduced |
| Assetmark, Inc | 89,850 | $35.2M | 0.08% | −2,541−2.8% | Reduced |
| State of New Jersey Common Pension Fund D | 90,129 | $35.3M | 0.13% | +3,400+3.9% | Added |
| Resona Asset Management Co.,Ltd. | 92,098 | $36.1M | 0.17% | −4,351−4.5% | Reduced |
| KLP Kapitalforvaltning AS | 92,641 | $36.3M | 0.14% | −200−0.2% | Reduced |
| Rockefeller Capital Management L.P. | 92,814 | $36.3M | 0.07% | −6,924−6.9% | Reduced |
| Creative Planning | 94,864 | $37.2M | 0.03% | +7,690+8.8% | Added |
| DnB Asset Management AS | 95,414 | $37.4M | 0.14% | +8,483+9.8% | Added |
| Banco Bilbao Vizcaya Argentaria, S.A. | 98,153 | $38.4M | 0.29% | +4,464+4.8% | Added |
| Country Trust Bank | 98,532 | $38.6M | 0.84% | +8,396+9.3% | Added |
| CI Private Wealth, LLC | 101,731 | $39.9M | 0.06% | −1,085−1.1% | Reduced |
| Public Employees Retirement System of Ohio | 102,732 | $40.2M | 0.13% | −3,323−3.1% | Reduced |
| Guggenheim Capital LLC | 103,125 | $40.4M | 0.30% | +1,905+1.9% | Added |
| Toronto Dominion Bank | 104,878 | $41.1M | 0.08% | −13,748−11.6% | Reduced |
| Voloridge Investment Management, LLC | 105,502 | $41.3M | 0.14% | +105,502 | New |
| Allianz Asset Management GmbH | 110,161 | $43.1M | 0.05% | −6,036−5.2% | Reduced |
| Mariner, LLC | 110,251 | $43.2M | 0.06% | −8,872−7.4% | Reduced |
| Freestone Grove Partners LP | 110,283 | $43.2M | 0.32% | +110,283 | New |
| Vontobel Holding Ltd. | 110,642 | $43.3M | 0.14% | +38,844+54.1% | Added |
| Storebrand Asset Management AS | 111,868 | $43.8M | 0.12% | +3,585+3.3% | Added |
| Nomura Asset Management Co Ltd | 112,333 | $44.0M | 0.11% | −46,583−29.3% | Reduced |
| NEOS Investment Management LLC | 113,533 | $44.5M | 0.33% | +37,296+48.9% | Added |
| Raiffeisen Bank International AG | 112,591 | $44.5M | 0.59% | −1,336−1.2% | Reduced |
| Treasurer of the State of North Carolina | 115,629 | $45.3M | 0.14% | −4,505−3.7% | Reduced |
| Sofinnova Investments, Inc. | 117,875 | $46.2M | 2.83% | +117,875 | New |
| Teacher Retirement System of Texas | 118,648 | $46.5M | 0.19% | −3,725−3.0% | Reduced |
| Capital International Ltd | 121,287 | $47.5M | 1.72% | −6,320−5.0% | Reduced |
| Schroder Investment Management Group | 121,587 | $48.1M | 0.04% | −13,380−9.9% | Reduced |
| Bowen Hanes & Co Inc | 124,434 | $48.7M | 1.22% | −56,365−31.2% | Reduced |
| Abn Amro Investment Solutions | 125,960 | $49.3M | 1.01% | −4,331−3.3% | Reduced |
| Allspring Global Investments Holdings, LLC | 126,863 | $51.3M | 0.08% | +323+0.3% | Added |
| British Columbia Investment Management Corp | 131,847 | $51.6M | 0.30% | −34,603−20.8% | Reduced |
| KBC Group NV | 133,602 | $52.3M | 0.13% | +937+0.7% | Added |
| Colony Group, LLC | 139,215 | $54.5M | 0.09% | −3,894−2.7% | Reduced |
| Intermede Investment Partners Ltd | 140,023 | $54.8M | 2.25% | −53,892−27.8% | Reduced |
| ABN AMRO Bank N.V. | 141,871 | $55.4M | 0.54% | +8,799+6.6% | Added |
| Stifel Financial Corp | 142,529 | $55.8M | 0.05% | +40,984+40.4% | Added |
| Truist Financial Corp | 143,864 | $56.3M | 0.08% | −66,225−31.5% | Reduced |
| Lansforsakringar Fondforvaltning AB (publ) | 146,563 | $57.4M | 0.30% | +5,273+3.7% | Added |
| Asset Management One Co.,Ltd. | 146,864 | $57.5M | 0.17% | +5,303+3.7% | Added |
| State of Wisconsin Investment Board | 148,349 | $58.1M | 0.13% | +5,411+3.8% | Added |
| Van Eck Associates Corp | 149,056 | $58.4M | 0.05% | +8,355+5.9% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 149,855 | $58.7M | 0.13% | −498−0.3% | Reduced |
| Quadrature Capital Ltd | 149,908 | $58.7M | 0.69% | +131,995+736.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 151,056 | $59.2M | 0.19% | +6,468+4.5% | Added |
| Woodline Partners LP | 153,272 | $60.0M | 0.28% | +61,608+67.2% | Added |
| Provident Investment Management, Inc. | 153,406 | $60.1M | 5.30% | −5,301−3.3% | Reduced |
| Birch Hill Investment Advisors LLC | 153,602 | $60.2M | 2.54% | +5,288+3.6% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 154,248 | $60.4M | 0.24% | −22,356−12.7% | Reduced |