Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Securian Asset Management, Inc | 12,316 | $4.82M | 0.13% | −1,126−8.4% | Reduced |
| M&T Bank Corp | 12,324 | $4.83M | 0.02% | −5,359−30.3% | Reduced |
| Hamilton Capital Partners Inc. | 12,329 | $4.83M | 0.20% | +2,813+29.6% | Added |
| Compagnie Lombard Odier SCmA | 12,565 | $4.92M | 0.05% | 00.0% | Unchanged |
| Thematics Asset Management | 12,629 | $4.95M | 0.22% | +2,031+19.2% | Added |
| Greenwood Capital Associates LLC | 12,812 | $5.02M | 0.58% | +2,514+24.4% | Added |
| Chicago Capital, LLC | 12,824 | $5.02M | 0.12% | −51−0.4% | Reduced |
| Leuthold Group, LLC | 12,843 | $5.03M | 0.55% | +12,843 | New |
| Maryland State Retirement & Pension System | 12,846 | $5.03M | 0.11% | +346+2.8% | Added |
| Gulf International Bank (UK) Ltd | 12,879 | $5.04M | 0.17% | −255−1.9% | Reduced |
| Fisher Funds Management LTD | 12,898 | $5.05M | 0.13% | 00.0% | Unchanged |
| Ossiam | 12,940 | $5.07M | 0.07% | +8,340+181.3% | Added |
| Vident Advisory, LLC | 13,222 | $5.18M | 0.05% | −5,278−28.5% | Reduced |
| Beacon Pointe Advisors, LLC | 13,284 | $5.20M | 0.04% | −2,745−17.1% | Reduced |
| Diversify Wealth Management, LLC | 12,214 | $5.20M | 0.30% | −774−6.0% | Reduced |
| Princeton Global Asset Management LLC | 13,359 | $5.23M | 0.87% | −1,666−11.1% | Reduced |
| Metis Global Partners, LLC | 13,424 | $5.26M | 0.12% | −694−4.9% | Reduced |
| Empowered Funds, LLC | 13,583 | $5.32M | 0.05% | +3,761+38.3% | Added |
| Omers Administration Corp | 13,754 | $5.39M | 0.04% | 00.0% | Unchanged |
| New Age Alpha Advisors, LLC | 13,939 | $5.46M | 0.23% | −1,761−11.2% | Reduced |
| Ethic Inc. | 13,971 | $5.47M | 0.09% | +2,476+21.5% | Added |
| Sequoia Financial Advisors, LLC | 13,980 | $5.48M | 0.03% | −393−2.7% | Reduced |
| Sivik Global Healthcare LLC | 14,000 | $5.48M | 2.88% | +14,000 | New |
| Tower Research Capital LLC (TRC) | 14,022 | $5.49M | 0.15% | −9,456−40.3% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 14,117 | $5.53M | 0.02% | −3,212−18.5% | Reduced |
| First Horizon Corp | 14,121 | $5.53M | 0.26% | +14,121 | New |
| Knuff & Co LLC | 14,184 | $5.56M | 1.61% | +188+1.3% | Added |
| Kestra Advisory Services, LLC | 14,391 | $5.64M | 0.03% | +33+0.2% | Added |
| Princeton Capital Management LLC | 14,438 | $5.65M | 1.52% | −37−0.3% | Reduced |
| Toroso Investments, LLC | 14,632 | $5.73M | 0.02% | +367+2.6% | Added |
| Atlantic Union Bankshares Corp | 14,688 | $5.75M | 0.11% | +5,741+64.2% | Added |
| Ameritas Investment Partners, Inc. | 14,831 | $5.81M | 0.18% | −78−0.5% | Reduced |
| Engineers Gate Manager LP | 14,843 | $5.81M | 0.07% | +14,843 | New |
| Gabelli Funds LLC | 15,002 | $5.88M | 0.04% | −1,327−8.1% | Reduced |
| Hartford Investment Management Co | 15,022 | $5.88M | 0.18% | −476−3.1% | Reduced |
| Park Avenue Securities LLC | 15,043 | $5.89M | 0.05% | −319−2.1% | Reduced |
| Prevail Innovative Wealth Advisors, LLC | 15,200 | $5.95M | 1.16% | +15,200 | New |
| Investment Management Corp of Ontario | 15,235 | $5.97M | 0.09% | +3,560+30.5% | Added |
| Northwest & Ethical Investments L.P. | 15,315 | $6.00M | 0.14% | +226+1.5% | Added |
| Puzo Michael J | 15,501 | $6.07M | 1.66% | +161+1.0% | Added |
| Janney Capital Management LLC | 15,707 | $6.15M | 0.38% | −524−3.2% | Reduced |
| Baldwin Investment Management, LLC | 15,748 | $6.17M | 0.71% | +1,207+8.3% | Added |
| Aptus Capital Advisors, LLC | 15,755 | $6.17M | 0.06% | +1,868+13.5% | Added |
| Anderson Hoagland & Co | 15,767 | $6.17M | 0.55% | −3,880−19.7% | Reduced |
| Trifecta Capital Advisors, LLC | 15,833 | $6.20M | 0.94% | +493+3.2% | Added |
| QRG Capital Management, Inc. | 15,833 | $6.20M | 0.08% | −3,203−16.8% | Reduced |
| Nia Impact Advisors, LLC | 15,933 | $6.24M | 2.03% | +46+0.3% | Added |
| Jefferies Financial Group Inc. | 16,000 | $6.27M | 0.06% | −18,615−53.8% | Reduced |
| LMR Partners LLP | 16,101 | $6.31M | 0.08% | +16,101 | New |
| Kentucky Retirement Systems | 16,147 | $6.32M | 0.17% | −427−2.6% | Reduced |
| Madison Asset Management, LLC | 16,201 | $6.34M | 0.07% | +2,009+14.2% | Added |
| Torray LLC | 16,255 | $6.37M | 0.86% | −624−3.7% | Reduced |
| Fulcrum Capital LLC | 16,256 | $6.37M | 1.31% | +458+2.9% | Added |
| Prudential PLC | 16,568 | $6.49M | 0.05% | −2,957−15.1% | Reduced |
| Silvercrest Asset Management Group LLC | 16,959 | $6.64M | 0.04% | +60.0% | Added |
| Broderick Brian C | 17,251 | $6.76M | 1.28% | −420−2.4% | Reduced |
| Sterling Capital Management LLC | 17,478 | $6.85M | 0.10% | −2,966−14.5% | Reduced |
| Motley Fool Asset Management LLC | 17,698 | $6.93M | 0.29% | +1,904+12.1% | Added |
| Blair William & Co | 17,990 | $7.05M | 0.02% | −8,087−31.0% | Reduced |
| Envestnet Portfolio Solutions, Inc. | 18,221 | $7.14M | 0.03% | +927+5.4% | Added |
| Mizuho Securities USA LLC | 18,674 | $7.30M | 0.15% | +924+5.2% | Added |
| Bridger Management, LLC | 18,778 | $7.35M | 3.96% | 00.0% | Unchanged |
| Mercer Global Advisors Inc | 18,784 | $7.36M | 0.01% | +261+1.4% | Added |
| HealthInvest Partners AB | 17,766 | $7.39M | 2.74% | −6,562−27.0% | Reduced |
| Grandfield & Dodd, LLC | 19,820 | $7.76M | 0.44% | +1,533+8.4% | Added |
| Heirloom Wealth Management | 19,966 | $7.82M | 1.89% | +333+1.7% | Added |
| Warren Averett Asset Management, LLC | 20,248 | $7.93M | 0.08% | +103+0.5% | Added |
| Azimuth Capital Investment Management LLC | 20,348 | $7.97M | 0.29% | −684−3.3% | Reduced |
| AIMZ Investment Advisors, LLC | 20,361 | $7.97M | 2.50% | −365−1.8% | Reduced |
| UniSuper Management Pty Ltd | 20,495 | $8.03M | 0.05% | +3,847+23.1% | Added |
| Prosight Management, LP | 20,500 | $8.03M | 1.93% | +20,500 | New |
| Wolverine Trading, LLC | 20,449 | $8.08M | 0.16% | +2,854+16.2% | Added |
| Wiley Bros.-Aintree Capital, LLC | 27,949 | $8.16M | 0.05% | +2,809+11.2% | Added |
| Camden National Bank | 20,892 | $8.18M | 1.14% | +430+2.1% | Added |
| Telos Capital Management, Inc. | 21,188 | $8.30M | 0.80% | +1,946+10.1% | Added |
| Modera Wealth Management, LLC | 21,853 | $8.56M | 0.10% | −1,252−5.4% | Reduced |
| Gotham Asset Management, LLC | 21,888 | $8.57M | 0.04% | +532+2.5% | Added |
| Fiduciary Trust Co | 21,921 | $8.59M | 0.10% | +4,402+25.1% | Added |
| EULAV Asset Management | 22,000 | $8.62M | 0.20% | −700−3.1% | Reduced |
| Norinchukin Bank, The | 22,026 | $8.63M | 0.12% | +90+0.4% | Added |
| Kennedy Capital Management, Inc. | 22,180 | $8.69M | 0.19% | +2,770+14.3% | Added |
| Fifth Third Bancorp | 22,223 | $8.70M | 0.03% | −2,001−8.3% | Reduced |
| Public Sector Pension Investment Board | 22,418 | $8.78M | 0.03% | +2,744+13.9% | Added |
| Somerville Kurt F | 22,643 | $8.87M | 1.47% | −543−2.3% | Reduced |
| GW Henssler & Associates Ltd | 22,791 | $8.93M | 0.45% | +28+0.1% | Added |
| Cary Street Partners Financial LLC | 22,923 | $8.98M | 0.23% | −586−2.5% | Reduced |
| Generali Asset Management SPA SGR | 23,569 | $9.23M | 0.20% | +6,942+41.8% | Added |
| Allianz SE | 23,921 | $9.37M | 0.20% | −14−0.1% | Reduced |
| PEAK6 LLC | 24,416 | $9.56M | 0.24% | −6,040−19.8% | Reduced |
| Americana Partners, LLC | 24,468 | $9.58M | 0.29% | +12,134+98.4% | Added |
| Capital Group Private Client Services, Inc. | 24,874 | $9.74M | 0.16% | −79,663−76.2% | Reduced |
| Jacobs Levy Equity Management, Inc | 24,949 | $9.77M | 0.04% | −26,007−51.0% | Reduced |
| Biondo Investment Advisors, LLC | 25,075 | $9.82M | 1.23% | +146+0.6% | Added |
| CAPROCK Group, Inc. | 25,216 | $9.86M | 0.24% | +25,216 | New |
| Pinnacle Associates Ltd | 25,367 | $9.93M | 0.13% | +259+1.0% | Added |
| Oppenheimer Asset Management Inc. | 25,460 | $9.97M | 0.11% | +3,972+18.5% | Added |
| Yousif Capital Management, LLC | 25,662 | $10.1M | 0.11% | −455−1.7% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 25,665 | $10.1M | 0.06% | +1,602+6.7% | Added |
| Generate Investment Management Ltd | 25,734 | $10.1M | 0.51% | +25,734 | New |
| LVM Capital Management Ltd | 25,840 | $10.1M | 0.97% | −4,230−14.1% | Reduced |