Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Cresset Asset Management, LLC | 7,592 | $2.97M | 0.01% | −4,635−37.9% | Reduced |
| Hedeker Wealth, LLC | 7,661 | $3.00M | 0.62% | −1,130−12.9% | Reduced |
| Entropy Technologies, LP | 7,693 | $3.01M | 0.23% | +7,693 | New |
| Transamerica Financial Advisors, Inc. | 7,715 | $3.02M | 0.25% | +84+1.1% | Added |
| Sectoral Asset Management Inc | 7,715 | $3.02M | 1.86% | +770+11.1% | Added |
| Johnson Investment Counsel Inc | 7,730 | $3.03M | 0.03% | −18−0.2% | Reduced |
| Agf Management Ltd | 7,735 | $3.03M | 0.01% | −9,150−54.2% | Reduced |
| Marex Group plc | 7,740 | $3.03M | 0.04% | +1,037+15.5% | Added |
| Edgestream Partners, L.P. | 7,746 | $3.03M | 0.09% | +1,331+20.7% | Added |
| Notis-McConarty Edward | 7,804 | $3.06M | 1.42% | +423+5.7% | Added |
| J.P. Marvel Investment Advisors, LLC | 7,855 | $3.08M | 0.45% | 00.0% | Unchanged |
| Peloton Wealth Strategists | 7,875 | $3.08M | 1.21% | −275−3.4% | Reduced |
| Baldwin Brothers Inc | 7,944 | $3.11M | 0.20% | −50−0.6% | Reduced |
| Diversify Advisory Services, LLC | 7,310 | $3.11M | 0.10% | +19+0.3% | Added |
| SummitTX Capital, L.P. | 7,955 | $3.12M | 0.13% | +7,955 | New |
| Brown Advisory Inc | 8,094 | $3.17M | 0.00% | +1,236+18.0% | Added |
| Northwestern Mutual Investment Management Company, LLC | 8,171 | $3.20M | 0.05% | −22−0.3% | Reduced |
| CIBC World Markets Inc. | 8,236 | $3.23M | 0.01% | −22,558−73.3% | Reduced |
| Ashford Capital Management Inc | 8,245 | $3.23M | 0.36% | +538+7.0% | Added |
| Privium Fund Management B.V. | 8,300 | $3.25M | 0.58% | 00.0% | Unchanged |
| Graphene Investments SAS | 8,300 | $3.25M | 2.06% | +1,500+22.1% | Added |
| Northwestern Mutual Wealth Management Co | 8,307 | $3.25M | 0.00% | −3,225−28.0% | Reduced |
| Central Trust Co | 8,393 | $3.29M | 0.07% | −623−6.9% | Reduced |
| Linden Thomas Advisory Services, LLC | 8,419 | $3.30M | 0.33% | +258+3.2% | Added |
| Bessemer Group Inc | 8,459 | $3.31M | 0.01% | +994+13.3% | Added |
| Commerzbank Aktiengesellschaft | 8,575 | $3.36M | 0.07% | −1,275−12.9% | Reduced |
| Mediolanum International Funds Ltd | 8,544 | $3.38M | 0.04% | +3,050+55.5% | Added |
| HB Wealth Management, LLC | 8,680 | $3.40M | 0.02% | −1,903−18.0% | Reduced |
| FIL Ltd | 8,706 | $3.41M | 0.00% | −12,408−58.8% | Reduced |
| Vinva Investment Management Ltd | 8,635 | $3.41M | 0.07% | −1,710−16.5% | Reduced |
| Davidson Capital Management Inc. | 8,795 | $3.44M | 0.77% | +1,571+21.7% | Added |
| Bensler, LLC | 8,836 | $3.46M | 0.36% | +41+0.5% | Added |
| Strategic Advisors LLC | 8,854 | $3.47M | 0.56% | +4,272+93.2% | Added |
| Banque Pictet & Cie SA | 8,858 | $3.47M | 0.03% | −8,079−47.7% | Reduced |
| Group One Trading, L.P. | 8,889 | $3.48M | 0.10% | +3,037+51.9% | Added |
| Howard Capital Management Inc. | 8,914 | $3.49M | 0.05% | −40.0% | Reduced |
| Tokio Marine Asset Management Co Ltd | 8,956 | $3.51M | 0.12% | +215+2.5% | Added |
| Sepio Capital, LP | 9,063 | $3.55M | 0.21% | +716+8.6% | Added |
| Miracle Mile Advisors, LLC | 9,075 | $3.55M | 0.05% | +1,040+12.9% | Added |
| Bulltick Wealth Management, LLC | 9,102 | $3.56M | 0.84% | +7+0.1% | Added |
| Crestwood Advisors Group LLC | 9,151 | $3.58M | 0.06% | −892−8.9% | Reduced |
| Horizon Investments, LLC | 9,194 | $3.60M | 0.05% | +1,352+17.2% | Added |
| Allstate Corp | 9,292 | $3.64M | 0.08% | +9,292 | New |
| Howe & Rusling Inc | 9,350 | $3.66M | 0.25% | −94−1.0% | Reduced |
| Vestmark Advisory Solutions, Inc. | 9,428 | $3.69M | 0.07% | +665+7.6% | Added |
| Empirical Finance, LLC | 9,493 | $3.72M | 0.18% | +487+5.4% | Added |
| Meiji Yasuda Asset Management Co Ltd. | 9,500 | $3.72M | 0.18% | −133−1.4% | Reduced |
| Zions Bancorporation, National Association | 9,638 | $3.77M | 0.19% | +9,452+5,081.7% | Added |
| Tema ETFs LLC | 9,651 | $3.78M | 0.31% | +1,583+19.6% | Added |
| XTX Topco Ltd | 9,690 | $3.79M | 0.20% | +5,165+114.1% | Added |
| Pinnacle Financial Partners Inc | 9,719 | $3.81M | 0.09% | +102+1.1% | Added |
| Baker Chad R | 9,740 | $3.81M | 0.66% | 00.0% | Unchanged |
| Cumberland Partners Ltd | 9,744 | $3.82M | 0.25% | −36,826−79.1% | Reduced |
| Little House Capital LLC | 9,760 | $3.82M | 0.88% | +3,930+67.4% | Added |
| F/M Investments LLC | 9,764 | $3.82M | 0.15% | −19,534−66.7% | Reduced |
| Parsons Capital Management Inc | 9,886 | $3.87M | 0.22% | −542−5.2% | Reduced |
| Keybank National Association | 10,039 | $3.93M | 0.01% | −639−6.0% | Reduced |
| Fayez Sarofim & Co | 10,058 | $3.94M | 0.01% | −300−2.9% | Reduced |
| Banque Cantonale Vaudoise | 10,122 | $3.96M | 0.15% | −407−3.9% | Reduced |
| Sigma Investment Counselors Inc | 10,139 | $3.97M | 0.21% | +840+9.0% | Added |
| Exchange Traded Concepts, LLC | 10,151 | $3.98M | 0.04% | +7,565+292.5% | Added |
| Synovus Financial Corp | 10,162 | $3.98M | 0.05% | +385+3.9% | Added |
| Jump Financial, LLC | 10,183 | $3.99M | 0.05% | −3,109−23.4% | Reduced |
| Kestra Private Wealth Services, LLC | 10,254 | $4.02M | 0.05% | +4,127+67.4% | Added |
| Morse Asset Management, Inc | 10,305 | $4.04M | 0.81% | +18+0.2% | Added |
| Brinker Capital Investments, LLC | 10,348 | $4.05M | 0.03% | −993−8.8% | Reduced |
| Joseph Group Capital Management | 10,368 | $4.06M | 1.15% | +2,608+33.6% | Added |
| Shorepoint Capital Partners LLC | 10,405 | $4.07M | 0.81% | +10,405 | New |
| Landscape Capital Management, L.L.C. | 10,484 | $4.11M | 0.26% | +7,405+240.5% | Added |
| Generali Investments CEE, investicni spolecnost, a.s. | 10,491 | $4.11M | 0.31% | 00.0% | Unchanged |
| Benjamin Edwards Inc | 10,496 | $4.11M | 0.05% | +862+8.9% | Added |
| E. Ohman J:or Asset Management AB | 10,520 | $4.12M | 0.10% | 00.0% | Unchanged |
| Channel Wealth LLC | 10,559 | $4.14M | 1.11% | −3,318−23.9% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 10,602 | $4.15M | 0.04% | −3,075−22.5% | Reduced |
| Siemens Fonds Invest GmbH | 10,742 | $4.21M | 0.23% | −173−1.6% | Reduced |
| Mark Sheptoff Financial Planning, LLC | 10,771 | $4.22M | 2.02% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 10,817 | $4.24M | 0.02% | +2,779+34.6% | Added |
| Voleon Capital Management LP | 10,830 | $4.24M | 0.10% | +8,137+302.2% | Added |
| Ci Investments Inc. | 10,991 | $4.30M | 0.02% | −2,137−16.3% | Reduced |
| GAM Holding AG | 11,015 | $4.31M | 0.27% | +462+4.4% | Added |
| AG2R la Mondiale Gestion D'Actifs | 9,788 | $4.36M | 0.22% | 00.0% | Unchanged |
| Machina Capital S.A.S. | 11,167 | $4.37M | 0.77% | +11,167 | New |
| Callan Family Office, LLC | 11,205 | $4.39M | 0.14% | −5,510−33.0% | Reduced |
| Slow Capital, Inc. | 11,300 | $4.43M | 0.52% | −514−4.4% | Reduced |
| PKO Investment Management Joint-Stock Co | 11,500 | $4.50M | 0.38% | −2,000−14.8% | Reduced |
| Two Sigma Advisers, LP | 11,500 | $4.50M | 0.01% | +10,600+1,177.8% | Added |
| Stenger Family Office, LLC | 10,721 | $4.50M | 0.95% | +10,721 | New |
| United Capital Financial Advisers, LLC | 11,512 | $4.51M | 0.03% | −1,610−12.3% | Reduced |
| Verition Fund Management LLC | 11,544 | $4.52M | 0.03% | −11,698−50.3% | Reduced |
| New Mexico Educational Retirement Board | 11,600 | $4.54M | 0.14% | −400−3.3% | Reduced |
| Kayne Anderson Rudnick Investment Management LLC | 11,619 | $4.55M | 0.01% | −394−3.3% | Reduced |
| GWM Advisors LLC | 11,718 | $4.59M | 0.02% | −211−1.8% | Reduced |
| Traynor Capital Management, Inc. | 11,965 | $4.69M | 0.27% | +290+2.5% | Added |
| ING Groep NV | 11,989 | $4.70M | 0.03% | +11,989 | New |
| Captrust Financial Advisors | 12,074 | $4.73M | 0.01% | −1,238−9.3% | Reduced |
| Covenant Asset Management, LLC | 12,104 | $4.74M | 0.90% | −51−0.4% | Reduced |
| Dai-Ichi Life Insurance Company, Ltd | 12,138 | $4.75M | 0.12% | −12,898−51.5% | Reduced |
| Northwest Bancshares, Inc. | 12,138 | $4.75M | 0.79% | +935+8.3% | Added |
| Kidder Stephen W | 12,298 | $4.82M | 1.38% | +168+1.4% | Added |
| Morningstar Investment Management LLC | 12,305 | $4.82M | 0.18% | +11,075+900.4% | Added |