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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,523
−12 vs. Q2 2025
Shares held
232.3M
−4.81M (−2.0%) vs. Q2 2025
Total value
$90.8B
−$14.7B (−14.0%) vs. Q2 2025
New holders
143
553 more added
Sold out
155
617 more reduced

28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 1,523 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ3 2025: $90.8B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.

Institutions holding VRTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Knollwood Investment Advisory, LLC4,988$1.95M0.18%00.0%Unchanged
Central Pacific Bank - Trust Division5,002$1.96M0.24%−557−10.0%Reduced
De Burlo Group Inc5,025$1.97M0.24%−43,740−89.7%Reduced
Meiji Yasuda Life Insurance Co5,038$1.97M0.06%−17−0.3%Reduced
Strategic Wealth Partners, Ltd.5,043$1.98M0.15%+23+0.5%Added
Parallel Advisors, LLC5,055$1.98M0.04%−211−4.0%Reduced
Ballentine Partners, LLC5,090$1.99M0.03%−338−6.2%Reduced
D.A. Davidson & Co.5,097$2.00M0.01%+241+5.0%Added
Signaturefd, LLC5,103$2.00M0.03%−197−3.7%Reduced
Wealthcare Advisory Partners LLC5,129$2.01M0.04%+1,967+62.2%Added
Future Fund LLC5,187$2.03M0.72%+1,184+29.6%Added
Bamco Inc5,200$2.04M0.01%−3,800−42.2%Reduced
AlphaCore Capital LLC5,255$2.06M0.07%+224+4.5%Added
Hager Investment Management Services, LLC5,272$2.06M1.12%−73−1.4%Reduced
Tiaa Trust, National Association5,282$2.07M0.01%−121−2.2%Reduced
RMR Wealth Builders5,323$2.08M0.17%+223+4.4%Added
BNP Paribas5,341$2.09M0.06%−235−4.2%Reduced
Mirabella Financial Services LLP5,377$2.10M0.18%+3,078+133.9%Added
Torrey Growth & Income Advisors5,400$2.11M0.62%+5,400New
Nwam LLC5,077$2.12M0.12%−10−0.2%Reduced
Trexquant Investment LP5,416$2.12M0.02%+5,416New
Ostrum Asset Management5,419$2.12M0.10%−475−8.1%Reduced
Wimmer Associates 1, LLC5,455$2.14M1.03%−137−2.4%Reduced
Wetherby Asset Management Inc5,470$2.14M0.09%−202−3.6%Reduced
Summit Trail Advisors, LLC5,484$2.15M0.03%−387−6.6%Reduced
Camden Capital, LLC5,498$2.15M0.15%+2,189+66.2%Added
APG Asset Management US Inc.5,334$2.16M0.02%00.0%Unchanged
MASTERINVEST Kapitalanlage GmbH5,544$2.17M0.21%−240−4.1%Reduced
Quadrant Capital Group LLC5,675$2.22M0.07%+570+11.2%Added
Highview Capital Management LLC5,703$2.23M0.82%−282−4.7%Reduced
Te Ahumairangi Investment Management Ltd5,725$2.24M0.38%−260−4.3%Reduced
GTS Securities LLC5,734$2.25M0.09%+4,086+247.9%Added
Nemes Rush Group LLC5,750$2.25M0.22%+27+0.5%Added
TD Waterhouse Canada Inc.5,597$2.26M0.01%−8,505−60.3%Reduced
Venturi Wealth Management, LLC5,788$2.27M0.11%−83−1.4%Reduced
Freedom Day Solutions, LLC5,814$2.28M0.62%+100+1.8%Added
Illumine Investment Management, LLC5,826$2.28M1.63%−49−0.8%Reduced
RSM US Wealth Management LLC5,854$2.29M0.03%−499−7.9%Reduced
Paradigm Financial Partners, LLC5,877$2.30M0.24%−1,685−22.3%Reduced
Meeder Advisory Services, Inc.5,912$2.32M0.11%−264−4.3%Reduced
Scotia Capital Inc.5,921$2.32M0.01%−563−8.7%Reduced
CWM, LLC5,942$2.33M0.01%−966−14.0%Reduced
Hall Laurie J Trustee5,950$2.33M0.76%+385+6.9%Added
Plato Investment Management Ltd6,026$2.34M0.16%+197+3.4%Added
Cohen Klingenstein LLC6,000$2.35M0.07%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.6,004$2.35M0.09%−752−11.1%Reduced
NewEdge Wealth, LLC5,648$2.36M0.03%−1,970−25.9%Reduced
Capstone Investment Advisors, LLC6,023$2.36M0.02%+3,664+155.3%Added
B&L Asset Management LLC6,049$2.37M1.21%−24−0.4%Reduced
Merit Financial Group, LLC6,087$2.38M0.02%−173−2.8%Reduced
Perigon Wealth Management, LLC6,108$2.39M0.05%+104+1.7%Added
Crossmark Global Holdings, Inc.6,143$2.41M0.04%−78−1.3%Reduced
Wedbush Securities Inc6,150$2.41M0.08%−472−7.1%Reduced
First National Bank of Mount Dora, Trust Investment Services6,175$2.42M0.54%−1,116−15.3%Reduced
Griffin Asset Management, Inc.6,220$2.44M0.27%−188−2.9%Reduced
Hantz Financial Services, Inc.6,230$2.44M0.04%+4,864+356.1%Added
BLI - Banque de Luxembourg Investments6,200$2.45M0.07%−300−4.6%Reduced
Coldstream Capital Management Inc6,406$2.51M0.03%+532+9.1%Added
Ieq Capital, LLC6,451$2.53M0.01%−9,768−60.2%Reduced
Harbour Capital Advisors, LLC6,181$2.54M0.52%−186−2.9%Reduced
Condor Capital Management6,507$2.55M0.21%+5+0.1%Added
Vision Capital Management, Inc.6,566$2.57M0.32%−306−4.5%Reduced
Ascent Group, LLC6,619$2.59M0.09%−2,033−23.5%Reduced
Burney Co6,631$2.60M0.08%−32,500−83.1%Reduced
Boomfish Wealth Group, LLC6,647$2.60M1.40%+1,404+26.8%Added
Elefante Mark B6,663$2.61M1.67%+831+14.2%Added
Shell Asset Management Co6,666$2.61M0.26%−10,515−61.2%Reduced
RDA Financial Network6,709$2.63M0.65%+1,858+38.3%Added
Sand Hill Global Advisors, LLC6,726$2.63M0.09%−594−8.1%Reduced
Kentucky Retirement Systems Insurance Trust Fund6,768$2.65M0.18%−266−3.8%Reduced
CIBC Private Wealth Group, LLC6,798$2.66M0.00%−231−3.3%Reduced
Wahed Invest LLC6,800$2.66M0.36%+6,800New
Thompson Siegel & Walmsley LLC6,803$2.66M0.04%−67−1.0%Reduced
Principal Securities, Inc.6,837$2.68M0.04%+237+3.6%Added
Kinneret Advisory, LLC6,864$2.69M0.23%−31−0.4%Reduced
South Dakota Investment Council6,880$2.69M0.05%−8,743−56.0%Reduced
North Star Asset Management Inc6,883$2.70M0.11%00.0%Unchanged
Nikko Asset Management Americas, Inc.6,902$2.70M0.03%+375+5.7%Added
MUFG Securities Americas Inc.6,914$2.71M0.17%+1,223+21.5%Added
Commerce Bank6,932$2.71M0.02%−558−7.4%Reduced
Glenview Trust Co6,981$2.73M0.04%−95−1.3%Reduced
Leavell Investment Management, Inc.6,985$2.74M0.12%−1,104−13.6%Reduced
ADAR1 Capital Management, LLC7,000$2.74M0.27%+7,000New
Jones Financial Companies LLLP7,124$2.75M0.00%+1,108+18.4%Added
Leonteq Securities AG7,028$2.75M0.15%+2,473+54.3%Added
Bokf, NA7,038$2.76M0.04%−1,216−14.7%Reduced
Delaney Dennis R7,048$2.76M1.38%−295−4.0%Reduced
Sumitomo Life Insurance Co7,093$2.78M0.09%−143−2.0%Reduced
Atom Investors LP7,109$2.78M0.21%+6,139+632.9%Added
Associated Banc-Corp7,118$2.79M0.07%−465−6.1%Reduced
Cavalier Investments, LLC7,807$2.79M1.12%+372+5.0%Added
Baird Financial Group, Inc.7,170$2.81M0.00%−9,222−56.3%Reduced
Codex Capital Asset Management L.L.C.7,250$2.84M1.07%−4,500−38.3%Reduced
Dempze Nancy E7,252$2.84M1.56%+72+1.0%Added
Neo Ivy Capital Management7,256$2.84M0.69%+7,256New
Private Advisor Group, LLC7,364$2.88M0.01%+160+2.2%Added
Univest Financial Corp7,364$2.88M0.16%+1,388+23.2%Added
EagleClaw Capital Managment, LLC7,385$2.89M0.40%−200−2.6%Reduced
Boston Private Wealth LLC7,415$2.90M0.16%−92−1.2%Reduced
Level Four Advisory Services, LLC7,586$2.97M0.10%+135+1.8%Added