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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Paces Ferry Wealth Advisors, LLC1,291$574.8K0.26%−61−4.5%Reduced
Koshinski Asset Management, Inc.1,300$578.8K0.04%+2+0.2%Added
Souders Financial Advisors1,309$582.8K0.07%+222+20.4%Added
American Trust1,311$583.7K0.05%+9+0.7%Added
Perennial Investment Advisors, LLC1,323$589.0K0.06%+80+6.4%Added
Whalen Wealth Management Inc.1,324$589.4K0.37%+1,324New
Insigneo Advisory Services, LLC1,325$589.9K0.05%+238+21.9%Added
Advisors Capital Management, LLC1,326$590.5K0.01%+55+4.3%Added
BankPlus Trust Department1,341$597.0K0.18%−15−1.1%Reduced
Pine Valley Investments Ltd Liability Co1,341$597.0K0.04%00.0%Unchanged
Independent Financial Group, LLC1,346$599.2K0.02%−993−42.5%Reduced
Nabity-Jensen Investment Management Inc1,348$600.1K0.44%00.0%Unchanged
PDT Partners, LLC1,353$602.4K0.03%−6,763−83.3%Reduced
Hancock Whitney Corp1,362$606.4K0.01%+19+1.4%Added
Hantz Financial Services, Inc.1,366$608.0K0.01%−18−1.3%Reduced
Kessler Investment Group, LLC1,373$611.3K0.25%00.0%Unchanged
Reuter James Wealth Management, LLC1,379$613.9K0.10%−188−12.0%Reduced
Sage Mountain Advisors LLC1,405$625.4K0.04%+163+13.1%Added
Mayflower Financial Advisors, LLC1,413$629.1K0.09%−78−5.2%Reduced
Legacy Wealth Asset Management, LLC1,416$630.4K0.16%−13−0.9%Reduced
Arete Wealth Advisors, LLC1,417$631.0K0.04%−29−2.0%Reduced
NorthCrest Asset Manangement, LLC1,380$634.2K0.02%−9−0.6%Reduced
Gibbs Wealth Management1,433$638.0K0.12%+435+43.6%Added
Baxter Bros Inc1,441$641.5K0.08%+213+17.3%Added
CoreCap Advisors, LLC1,442$642.0K0.03%+641+80.0%Added
Sovran Advisors, LLC1,385$645.9K0.07%−4,104−74.8%Reduced
Pitcairn Co1,457$648.7K0.04%−328−18.4%Reduced
First Pacific Financial1,465$652.2K0.10%−116−7.3%Reduced
Harbor Investment Advisory, LLC1,474$656.2K0.06%00.0%Unchanged
Private Wealth Partners, LLC1,485$661.1K0.05%00.0%Unchanged
SBI Securities Co., Ltd.1,488$662.5K0.02%+9+0.6%Added
Avantax Planning Partners, Inc.1,489$662.9K0.02%+295+24.7%Added
Arcataur Capital Management LLC1,496$666.0K0.21%00.0%Unchanged
Holderness Investments Co1,497$666.5K0.14%+133+9.8%Added
Moloney Securities Asset Management, LLC1,498$666.9K0.08%−300−16.7%Reduced
Kensington Investment Counsel, LLC1,503$669.1K0.29%+7+0.5%Added
Scott Marsh Financial, LLC1,504$669.6K0.25%+1,504New
Spinnaker Trust1,505$670.0K0.04%+260+20.9%Added
Global Assets Advisory, LLC1,484$671.0K0.26%−1,124−43.1%Reduced
Renaissance Group LLC1,519$676.3K0.03%−195−11.4%Reduced
Conning Inc.1,544$687.4K0.02%−42−2.6%Reduced
IHT Wealth Management, LLC1,547$688.7K0.02%+5+0.3%Added
Lantern Wealth Advisors, LLC1,550$690.1K0.41%+1,550New
Destination Wealth Management1,553$691.4K0.02%−1,724−52.6%Reduced
Resonant Capital Advisors, LLC1,558$693.6K0.04%+108+7.4%Added
Exencial Wealth Advisors, LLC1,560$694.5K0.02%−76−4.6%Reduced
LOM Asset Management Ltd1,565$697.0K0.24%+1,565New
Sava Infond d.o.o.1,570$699.0K0.11%00.0%Unchanged
Gsa Capital Partners LLP1,571$699.0K0.05%+837+114.0%Added
Lord, Abbett & Co. LLC1,572$700.0K0.00%−1,375−46.7%Reduced
J.W. Cole Advisors, Inc.1,584$705.2K0.01%−169−9.6%Reduced
First Manhattan Co1,585$705.6K0.00%+30+1.9%Added
Fukoku Mutual Life Insurance Co1,589$707.4K0.05%−226−12.5%Reduced
Peapack Gladstone Financial Corp1,596$711.0K0.01%−181−10.2%Reduced
Perfromance Wealth Partners, LLC1,600$712.3K0.02%−3−0.2%Reduced
BKD Wealth Advisors, LLC1,600$712.3K0.02%+152+10.5%Added
First Citizens Bank & Trust Co1,603$713.7K0.01%−2,594−61.8%Reduced
Journey Strategic Wealth LLC1,603$713.7K0.02%+809+101.9%Added
Nomura Holdings Inc1,604$714.1K0.01%−3,130−66.1%Reduced
Vista Investment Management1,614$718.6K0.27%−40−2.4%Reduced
Frisch Financial Group, Inc.1,614$719.0K0.18%+1,614New
Resources Investment Advisors, LLC.1,615$719.2K0.01%−140−8.0%Reduced
Anchor Investment Management, LLC1,617$719.9K0.06%+2+0.1%Added
Lee Johnson Capital Management, LLC1,619$720.8K0.25%+1,619New
Flagship Harbor Advisors, LLC1,620$721.2K0.03%+85+5.5%Added
KRS Capital Management, LLC1,622$722.1K0.48%−115−6.6%Reduced
Clarius Group, LLC1,625$723.5K0.04%−193−10.6%Reduced
Campbell Newman Asset Management Inc1,626$723.9K0.06%−5−0.3%Reduced
Eastern Bank1,635$727.9K0.01%+25+1.6%Added
GTS Securities LLC1,648$733.7K0.03%−418−20.2%Reduced
Oxler Private Wealth LLC1,674$745.3K0.23%00.0%Unchanged
AdvisorNet Financial, Inc1,674$745.3K0.05%+201+13.6%Added
Kornitzer Capital Management Inc1,700$756.8K0.02%+1,032+154.5%Added
Raab & Moskowitz Asset Management LLC1,701$757.3K0.18%00.0%Unchanged
Advisory Alpha, LLC1,701$757.3K0.02%+187+12.4%Added
Rehmann Capital Advisory Group1,708$760.4K0.05%+144+9.2%Added
Alpha Family Trust1,720$765.7K0.38%00.0%Unchanged
Great Lakes Retirement, Inc.1,724$767.5K0.09%−5−0.3%Reduced
Triangle Securities Wealth Management1,728$769.3K0.19%+10+0.6%Added
Fortis Capital Advisors, LLC1,735$772.4K0.14%−19−1.1%Reduced
Prudent Man Advisors, LLC1,735$772.4K0.25%+376+27.7%Added
Continuum Advisory, LLC1,739$774.2K0.09%+74+4.4%Added
Transcend Wealth Collective, LLC1,744$776.3K0.06%−1,522−46.6%Reduced
CX Institutional1,754$781.0K0.03%−33−1.8%Reduced
Hartford Funds Management Co LLC1,754$781.9K0.07%+394+29.0%Added
Catalytic Wealth RIA, LLC1,765$785.8K0.06%+1,314+291.4%Added
Altfest L J & Co Inc1,766$786.2K0.09%+120+7.3%Added
Strategic Investment Advisors1,774$788.4K0.08%+39+2.2%Added
Wrapmanager Inc1,774$789.8K0.19%−69−3.7%Reduced
Great Diamond Partners, LLC1,776$790.7K0.17%+423+31.3%Added
Howland Capital Management LLC1,776$790.7K0.03%−199−10.1%Reduced
Brookwood Investment Group LLC1,779$792.0K0.13%+11+0.6%Added
Alta Wealth Advisors LLC1,792$797.8K0.38%00.0%Unchanged
Checchi Capital Advisers, LLC1,794$798.7K0.06%−41−2.2%Reduced
1248 Management, LLC1,795$799.1K0.30%00.0%Unchanged
IFP Advisors, Inc1,590$800.1K0.02%−1,074−40.3%Reduced
Acima Private Wealth, LLC1,806$804.0K0.27%00.0%Unchanged
Strategic Blueprint, LLC1,807$804.5K0.04%+309+20.6%Added
Appleton Partners Inc1,808$805.0K0.06%+15+0.8%Added
Oak Ridge Investments LLC1,816$808.5K0.06%−17−0.9%Reduced